Lacidipine remodels protein folding and Ca2+ homeostasis in Gaucher's disease fibroblasts: A mechanism to rescue mutant glucocerebrosidase

Chemistry and Biology

Volumn 18, Issue 6, 2011, Pages 766-776

  Wang, Fan ^a   Chou, Ann ^b   Segatori, Laura ^a,b  

^a Rice University   (United States)

^b RICE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL L TYPE; DIHYDROPYRIDINE DERIVATIVE; GLUCOSYLCERAMIDASE; HEAT SHOCK PROTEIN; LACIDIPINE; MOLECULAR CHAPERONE GRP78;

ARTICLE; CELL CULTURE; CHEMISTRY; DRUG EFFECT; ENZYMOLOGY; FIBROBLAST; GAUCHER DISEASE; GENETICS; HUMAN; METABOLISM; MUTATION; PROTEIN FOLDING; UNFOLDED PROTEIN RESPONSE;

CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, L-TYPE; CELLS, CULTURED; DIHYDROPYRIDINES; FIBROBLASTS; GAUCHER DISEASE; GLUCOSYLCERAMIDASE; HEAT-SHOCK PROTEINS; HUMANS; MUTATION; PROTEIN FOLDING; UNFOLDED PROTEIN RESPONSE;

EID: 79959515821     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2011.04.008     Document Type: Article

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