Repression of apurinic/apyrimidinic endonuclease by p53-dependent apoptosis in hydronephrosis-induced rat kidney

Free Radical Research

Volumn 45, Issue 6, 2011, Pages 728-734

  Chang, In Youb ^a,b   Kim, Jin Nam ^c   Jun, Jae Yeoul ^a,d   You, Ho Jin ^a,b   Jeon, Young Jin ^a,b   Park, Kyeong Soo ^e   Yoon, Sang Pil ^a,f  

^a Korean DNA Repair Research Center   (South Korea)

^b Chosun University   (South Korea)

^c Inje University College of Medicine   (South Korea)

^d Department of Physiology ^*  (South Korea)

^e Seonam University   (South Korea)

^f Jeju National University School of Medicine   (South Korea)

Author keywords

APE; apoptosis; hydronephrosis; p53

Indexed keywords

CASPASE 3; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; HISTONE H2AX; PROTEIN BAX; PROTEIN P53;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOARCHITECTURE; DNA DAMAGE; EXCISION REPAIR; HYDRONEPHROSIS; IMMUNOLOCALIZATION; IMMUNOREACTIVITY; KIDNEY; MALE; NONHUMAN; RAT; URETER LIGATION; URETER OBSTRUCTION; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CASPASE 3; DEOXYGUANOSINE; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; ENZYME REPRESSION; HYDRONEPHROSIS; KIDNEY; MALE; OXIDATION-REDUCTION; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA; RATTUS;

EID: 79959460603     PISSN: 10715762     EISSN: 10292470     Source Type: Journal    
DOI: 10.3109/10715762.2011.574289     Document Type: Article

References (27)

1. Chevalier RL. Pathogenesis of renal injury in obstructive uropathy. Curr Opin Pediatr 2006;18:153-160.
2. Docherty NG, O' S ullivan OE, Healy DA, Fitzpatrick JM, Watson WG. Evidence that inhibition of tubular cell apoptosis protects against renal damage and development of fibrosis following ureteric obstruction. Am J Physiol Renal Physiol 2006;290:F4-F13.
3. Chevalier RL, Thornhill BA, Wolstenholme JT, Kim A. Unilateral ureteral obstruction in early development alters renal growth: dependence on the duration of obstruction. J Urol 1999;161:309-313. (Pubitemid 29422353)
4. Hauser P, Kainz A, Perco P, Bergmeister H, Mitterbauer C, Schwarz C, Regele HM, Mayer B, Meyer TW, Oberbauer R. Transcriptional response in the unaffected kidney after contralateral hydronephrosis or nephrectomy. Kidney Int 2005; 68:2497-2507. (Pubitemid 43250996)
5. Cachat F, Lange-Sperandio B, Chang AY, Kiley SC, Thornhill BA, Forbes MS, Chevalier RL. Ureteral obstruction in neonatal mice elicits segment-specifi c tubular cell responses leading to nephron loss. Kidney Int 2003;63:564-575. (Pubitemid 36126802)
6. Thornhill BA, Forbes MS, Marcinko ES, Chevalier RL. Glomerulotubular disconnection in neonatal mice after relief of partial ureteral obstruction. Kidney Int 2007;72:1103-1112. (Pubitemid 47609049)
7. Sunami R, Sugiyama H, Wang DH, Kobayashi M, Maeshima Y, Yamasaki Y, Masuoka N, Ogawa N, Kira S, Makino H. Acatalasemia sensitizes renal tubular epithelial cells to apoptosis and exacerbates renal fibrosis after unilateral ureteral obstruction. Am J Physiol Renal Physiol 2004;286: F1030-F1038. (Pubitemid 38656356)
8. Yang T, Kong C, Watters D, Johnson DW, Gobe G. Activation of ERK in renal fibrosis after unilateral ureteral obstruction: modulation by antioxidants. Kidney Int 2005; 67:931-943. (Pubitemid 41623317)
9. Power RE, Doyle BT, Higgins D, Brady HR, Fitzpatrick JM, Watson RW. Mechanical deformation induced apoptosis in human proximal renal tubular epithelial cells is caspase dependent. J Urol 2004;171:457-461. (Pubitemid 37549211)
10. Bernstein C, Bernstein H, Payne CM, Garewal H. DNA repair/pro-apoptotic dual role proteins in fibe major DNA repair pathways: fail-sale protection against carcinogenesis. Mutat Res 2002;511:145-178. (Pubitemid 34621252)
11. Moon C, Moon HY, Kim CS. The expressions of p53, β-H2AX and Ku70/Ku80 that was caused by hydronephrosis in the kidney of rats. Korean J Urol 2007;48:976-983. (Pubitemid 47496991)
12. Sharma S, Choudhary B, Raghavan SC. Effi ciency of nonhomologous DNA end joining varies among somatic tissues, despite similarity in mechanism. Cell Mol Life Sci 2011;68:661-676.
13. Tell G, Quadrifoglio F, Tiribelli C, Kelley MR. The many functions of APE1/Ref-1: not only a DNA repair enzyme. Antioxid Redox Signal 2009;11:601-620.
14. Fuchs S, Philippe J, Corvol P, Pinet F. Implication of Ref-1 in the repression of rennin gene transcription by intracellular calcium. J Hypertens 2003;21:327-335. (Pubitemid 36269704)
15. Xiong JJ, Zhang Y, Wang JL, Bao GD, Zhang Y, Zhu ZY. Silencing of Ref-1 expression by retrovirus-mediated shRNA sensitizes HEK293 cells to hydrogen peroxide-induced apoptosis. Biosci Biotechnol Biochem 2008;72:3206-3210.
16. Tan Y, Nakagawa Y, Akiyama K, Wakabayashi H, Sarker AH, Seki S. cDNA cloning of rat major AP endonuclease (APEX nuclease) and analyses of its mRNA expression in rat tissues. Acta Med Okayama 1996;50:53-60. (Pubitemid 126445521)
17. Chevalier RL, Cachat R. Role of angiotensin II in chronic ureteral obstruction. In: Wolf G, editor. The renin-angiotensin system and progression of renal diseases, edn 1. Basel: Karger; 2001. p 250-260.
18. Lane DP. p53, guardian of the genome. Nature 1992;358: 15-16.
19. Chipuk JE, Bouchier-Hayes L, Kuwana T, Newmeyer DD, Green DR. PUMA couples the nuclear and cytoplasmic proapoptotic function of p53. Science 2005;309:1732-1735. (Pubitemid 41285944)
20. Zaky A, Busso C, Izumi T, Chattopadhyay R, Bassiouny A, Mitra S, Bhakat KK. Regulation of the human APendonuclease (APE/Ref-1) expression by the tumor suppressor p53 in response to DNA damage. Nucleic Acids Res 2008;36:1555-1566. (Pubitemid 351426108)
21. R adovic N, Cuzic S, Knotek M. Effect of unilateral ureteral obstruction and anti-angiotensin II treatment on renal tubule and interstitial cell apoptosis in rats. Croat Med J 2008;49: 600-607.
22. Tsuruya K, Furuichi M, Tominaga Y, Shinozaki M, Tokumoto M, Yoshimitsu T, Fukuda K, Kanai H, Hirakata H, Iida M, Nakabeppu Y. Accumulation of 8-oxoguanine in the cellular DNA and the alteration of the OGG1 expression during ischemia-reperfusion injury in the rat kidney. DNA Repair (Amst) 2003;2:211-219.
23. Simone S, Gorin Y, Velagapudi C, Abbound HE, Habib SL. Mechanism of oxidative DNA damage in diabetes: tuberin inactivation and downregulation of DNA repair enzyme 8-oxo-7,8-dihydro-2 ' -deoxyguanosine-DNA glycosylase. Diabetes 2008;57:2626-2636.
24. Habib SL, Simone S, Barnes JJ, Abboud HE. Tuberin haploinsuffi ciency is associated with the loss of OGG1 in rat kidney tumors. Mol Cancer 2008;7:10.
25. Jones DA, Shahed J, Shoskes DA. Modulation of apoptotic and inflammatory genes by bioflavonoids and angiotensin II inhibition in ureteral obstruction. Urology 2000; 56:346-351. (Pubitemid 30495609)
26. Satoh M, Kahihara N, Yamasaki Y, Maruyama K, Okamoto K, Maeshima Y, Sugiyama H, Sugaya T, Murakami K, Makino H. Renal interstitial fibrosis is reduced in angiotensin II type 1a receptor-defi cient mice. J Am Soc Nephrol 2001;12:317-325. (Pubitemid 32116373)
27. Chen CO, Park MH, Forbes MS, Thornhill BA, Kiley SC, Yoo KH, Chevalier RL. Angiotensin-converting enzyme inhibition aggravates renal intersticial injury resulting from partial unilateral ureteral obstruction in the neonatal rat. Am J Physiol Renal Physiol 2007;292:F946-F955. (Pubitemid 46393420)