메뉴 건너뛰기




Volumn 35, Issue 2, 2007, Pages 199-207

The rat mammary gland: Morphologic changes as an indicator of systemic hormonal perturbations induced by xenobiotics

Author keywords

Endocrine disrupters; Mammary gland; Preclinical safety assessment risk management; Rat pathology; Reproductive system; Toxicologic pathology; Xenobiotics

Indexed keywords

ANDROGEN; DOPAMINE RECEPTOR BLOCKING AGENT; ESTRADIOL; ESTROGEN DERIVATIVE; FLUTAMIDE; FULVESTRANT; GROWTH HORMONE; METOCLOPRAMIDE; MIFEPRISTONE; PROGESTERONE; PROLACTIN; RECOMBINANT GROWTH HORMONE; TAMOXIFEN; TESTOSTERONE; XENOBIOTIC AGENT;

EID: 33847786009     PISSN: 01926233     EISSN: 15331601     Source Type: Journal    
DOI: 10.1080/01926230601156260     Document Type: Review
Times cited : (58)

References (67)
  • 1
    • 33847769491 scopus 로고
    • The development of the mammary gland in normal and castrated male rats after the age of 21 days
    • Ahren, K., and Etieinne, M. (1957). The development of the mammary gland in normal and castrated male rats after the age of 21 days. Acta Physiol Scand 41(2-3), 283-300.
    • (1957) Acta Physiol Scand , vol.41 , Issue.2-3 , pp. 283-300
    • Ahren, K.1    Etieinne, M.2
  • 2
    • 0012231171 scopus 로고
    • Development of the mammary gland of the rat
    • Astwood, E. B., Geschickter, C. F., and Rausch, E. O. (1937). Development of the mammary gland of the rat. Amer J Anat 61, 373-405.
    • (1937) Amer J Anat , vol.61 , pp. 373-405
    • Astwood, E.B.1    Geschickter, C.F.2    Rausch, E.O.3
  • 3
    • 0033791461 scopus 로고    scopus 로고
    • Progesterone induces side-branching of the ductal epithelium in the mammary glands of peripubertal mice
    • Atwood, C. S., Hovey, R. C., Glover, J. P., Chepko, G., Ginsburg, E., Robison, W. G., and Vonderhaar, B. K. (2000). Progesterone induces side-branching of the ductal epithelium in the mammary glands of peripubertal mice. J Endocrinol 167(1), 39-52.
    • (2000) J Endocrinol , vol.167 , Issue.1 , pp. 39-52
    • Atwood, C.S.1    Hovey, R.C.2    Glover, J.P.3    Chepko, G.4    Ginsburg, E.5    Robison, W.G.6    Vonderhaar, B.K.7
  • 4
    • 0030451788 scopus 로고    scopus 로고
    • Extrapituitary prolactin: Distribution, regulation, functions and clinical aspects
    • Ben-Jonathon, N., Mershon, J. L., Allen, D. L., and Steinmetz, R. W. (1996). Extrapituitary prolactin: distribution, regulation, functions and clinical aspects. Endocr Rev 17, 639-69.
    • (1996) Endocr Rev , vol.17 , pp. 639-669
    • Ben-Jonathon, N.1    Mershon, J.L.2    Allen, D.L.3    Steinmetz, R.W.4
  • 5
    • 0031694202 scopus 로고    scopus 로고
    • Effects of 17 beta-estradiol on serum hormone concentrations and estrous cycle in female Crl:CD BR rats: Effects on parental and first generation rats
    • Biegel, L. B., Cook, L. C., Hurtt, M. E., and O'Connor, J. C. (1998). Effects of 17 beta-estradiol on serum hormone concentrations and estrous cycle in female Crl:CD BR rats: effects on parental and first generation rats. Toxicol Sci 44, 143-54.
    • (1998) Toxicol Sci , vol.44 , pp. 143-154
    • Biegel, L.B.1    Cook, L.C.2    Hurtt, M.E.3    O'Connor, J.C.4
  • 8
    • 0025796717 scopus 로고
    • Sexual dimorphism of the normal rat mammary gland
    • Cardy, R. H. (1991). Sexual dimorphism of the normal rat mammary gland. Vet Pathol 28(2), 139-45.
    • (1991) Vet Pathol , vol.28 , Issue.2 , pp. 139-145
    • Cardy, R.H.1
  • 9
    • 85047682437 scopus 로고    scopus 로고
    • Synergistic action of prolactin (PRL) and androgen on PRL-inducible protein gene expression in human breast cancer cells: A unique model for functional cooperation between signal transducer and activator of transcription-5 and androgen receptor
    • Carsol, J. L., Gingras, S., and Simard, J. (2002). Synergistic action of prolactin (PRL) and androgen on PRL-inducible protein gene expression in human breast cancer cells: a unique model for functional cooperation between signal transducer and activator of transcription-5 and androgen receptor. Mol Endocrinol 16(7), 1696-710.
    • (2002) Mol Endocrinol , vol.16 , Issue.7 , pp. 1696-1710
    • Carsol, J.L.1    Gingras, S.2    Simard, J.3
  • 10
    • 0014769905 scopus 로고
    • Fetal mammary gland differentiation in vitro in response to hormones. II. Biochemical findings
    • Ceriani, R. L. (1970). Fetal mammary gland differentiation in vitro in response to hormones. II. Biochemical findings. Develop Biol 21(4), 530-46.
    • (1970) Develop Biol , vol.21 , Issue.4 , pp. 530-546
    • Ceriani, R.L.1
  • 12
    • 0031667327 scopus 로고    scopus 로고
    • Effects of dietary 17b-estradiol exposure on serum hormone concentrations and testicular parameters in male Crl:CD BR rats
    • Cook, J. C., Johnson, L., O'Connor, J. C., Biegel, L. B., Krams, C. H., Frame, S. R., and Hurtt, M. E. (1998). Effects of dietary 17b-estradiol exposure on serum hormone concentrations and testicular parameters in male Crl:CD BR rats. Toxicol Sci 44, 155-68.
    • (1998) Toxicol Sci , vol.44 , pp. 155-168
    • Cook, J.C.1    Johnson, L.2    O'Connor, J.C.3    Biegel, L.B.4    Krams, C.H.5    Frame, S.R.6    Hurtt, M.E.7
  • 14
    • 0001954766 scopus 로고
    • Postnatal development of the rodent mammary gland
    • M. C. Neville and C. W. Daniel, eds, pp, Plenum Press, New York
    • Daniel, C.W., and Silberstein G. B. (1987). Postnatal development of the rodent mammary gland. In: The Mammary Gland: Development, Regulation and Function (M. C. Neville and C. W. Daniel, eds.), pp 1-36, Plenum Press, New York.
    • (1987) The Mammary Gland: Development, Regulation and Function , pp. 1-36
    • Daniel, C.W.1    Silberstein, G.B.2
  • 15
    • 0027424393 scopus 로고
    • Evidence that the growth hormone receptor mediates differentiation and development of the mammary gland
    • Feldman, M., Ruan, W., Cunningham, B. C., Wells, J. A., and Kleinberg, D. L. (1993). Evidence that the growth hormone receptor mediates differentiation and development of the mammary gland. Endocrinology 133(4), 1602-8.
    • (1993) Endocrinology , vol.133 , Issue.4 , pp. 1602-1608
    • Feldman, M.1    Ruan, W.2    Cunningham, B.C.3    Wells, J.A.4    Kleinberg, D.L.5
  • 17
    • 0017818331 scopus 로고
    • Progesterone and glucocorticoid in relation to the growth and differentiation of mammary epithelium
    • Freeman, C. S., and Topper, Y. J. (1978). Progesterone and glucocorticoid in relation to the growth and differentiation of mammary epithelium. J Toxicol Environ Health 4(2-3), 269-82.
    • (1978) J Toxicol Environ Health , vol.4 , Issue.2-3 , pp. 269-282
    • Freeman, C.S.1    Topper, Y.J.2
  • 18
    • 0035162210 scopus 로고    scopus 로고
    • Prolactin, growth hormone, and epidermal growth factor activate Stat5 in different compartments of mammary tissue and exert different and overlapping developmental effects
    • Gallego, M. I., Binart, N., Robinson, G. W., Okagaki, R., Coschigano, K. T., Perry, J., Kopchick, J .J., Oka, T., Kelly, P. A., and Hennighausen, L. (2001). Prolactin, growth hormone, and epidermal growth factor activate Stat5 in different compartments of mammary tissue and exert different and overlapping developmental effects. Develop Biol 229(1), 163-75.
    • (2001) Develop Biol , vol.229 , Issue.1 , pp. 163-175
    • Gallego, M.I.1    Binart, N.2    Robinson, G.W.3    Okagaki, R.4    Coschigano, K.T.5    Perry, J.6    Kopchick, J.J.7    Oka, T.8    Kelly, P.A.9    Hennighausen, L.10
  • 19
    • 0017054809 scopus 로고
    • Role of testosterone and its metabolites in the differentiation of the mammary gland in rats
    • Goldman, A. S., Shapiro, B., and Neumann, F. (1976). Role of testosterone and its metabolites in the differentiation of the mammary gland in rats. Endocrinology 99(6), 1490-5.
    • (1976) Endocrinology , vol.99 , Issue.6 , pp. 1490-1495
    • Goldman, A.S.1    Shapiro, B.2    Neumann, F.3
  • 20
    • 0027201501 scopus 로고
    • Two-year carcinogenicity study of tamoxifen in Alderley Park Wistar-derived rats
    • Greaves, P., Goonetilleke, R., Nunn, G., Topham, J., and Orton, T. (1993). Two-year carcinogenicity study of tamoxifen in Alderley Park Wistar-derived rats. Cancer Res. 53(17), 3919-24.
    • (1993) Cancer Res , vol.53 , Issue.17 , pp. 3919-3924
    • Greaves, P.1    Goonetilleke, R.2    Nunn, G.3    Topham, J.4    Orton, T.5
  • 21
    • 4944237307 scopus 로고    scopus 로고
    • Prolactin and the prolactin receptor: New targets of an old hormone
    • Harris, J., Stanford, P. M., Oakes, S. R., and Ormandy, C. J. (2004). Prolactin and the prolactin receptor: new targets of an old hormone. Ann Med. 36(6), 414-25.
    • (2004) Ann Med , vol.36 , Issue.6 , pp. 414-425
    • Harris, J.1    Stanford, P.M.2    Oakes, S.R.3    Ormandy, C.J.4
  • 22
    • 0032601757 scopus 로고    scopus 로고
    • Regulation of mammary gland growth and morphogenesis by the mammary fat pad: A species comparison
    • Hovey, R. C., McFadden, T. B., and Akers, R. M. (1999). Regulation of mammary gland growth and morphogenesis by the mammary fat pad: a species comparison. J Mamm Gland Biol Neoplasia 4(1), 53-68.
    • (1999) J Mamm Gland Biol Neoplasia , vol.4 , Issue.1 , pp. 53-68
    • Hovey, R.C.1    McFadden, T.B.2    Akers, R.M.3
  • 23
    • 0036129964 scopus 로고    scopus 로고
    • Hormone/ growth factor interactions mediating epithelial/stromal communication in mammary gland development and carcinogenesis
    • Imagawa, W., Pedchenko, V. K., Helber, J., and Zhang, H. (2002). Hormone/ growth factor interactions mediating epithelial/stromal communication in mammary gland development and carcinogenesis. J Ster Biochem Mol Biol 80(2), 213-30.
    • (2002) J Ster Biochem Mol Biol , vol.80 , Issue.2 , pp. 213-230
    • Imagawa, W.1    Pedchenko, V.K.2    Helber, J.3    Zhang, H.4
  • 25
    • 0031724569 scopus 로고    scopus 로고
    • Quantitative studies of ductal versus alveolar differentiation from rat mammary clonogens
    • Kamiya, K., Gould, M. N., and Clifton, K. H. (1998). Quantitative studies of ductal versus alveolar differentiation from rat mammary clonogens. Proc Soc Exper Biol & Med 219(3), 217-25.
    • (1998) Proc Soc Exper Biol & Med , vol.219 , Issue.3 , pp. 217-225
    • Kamiya, K.1    Gould, M.N.2    Clifton, K.H.3
  • 27
    • 0141924527 scopus 로고    scopus 로고
    • Tamoxifen: 28-day oral toxicity study in the rat based on the enhanced OECD test guideline 407 to detect endocrine effects
    • Kennel, P., Pallen, C., Barale-Thomas, E., Espuna, G., and Bars, R. (2003). Tamoxifen: 28-day oral toxicity study in the rat based on the enhanced OECD test guideline 407 to detect endocrine effects. Arch Toxicol 77, 487-99.
    • (2003) Arch Toxicol , vol.77 , pp. 487-499
    • Kennel, P.1    Pallen, C.2    Barale-Thomas, E.3    Espuna, G.4    Bars, R.5
  • 28
    • 0030621577 scopus 로고    scopus 로고
    • Early mammary development: Growth hormone and IGF-1
    • Kleinberg, D. L. (1997). Early mammary development: growth hormone and IGF-1. J Mamm Gland Biol Neoplasia 2(1), 49-57.
    • (1997) J Mamm Gland Biol Neoplasia , vol.2 , Issue.1 , pp. 49-57
    • Kleinberg, D.L.1
  • 29
    • 0025323966 scopus 로고
    • Non-lactogenic effects of growth hormone on growth and insulinlike growth factor-I messenger ribonucleic acid of rat mammary gland
    • Kleinberg D. L., Ruan, W., Catanese, V., Newman, C. B., and Feldman, M. (1990). Non-lactogenic effects of growth hormone on growth and insulinlike growth factor-I messenger ribonucleic acid of rat mammary gland. Endocrinology 126(6), 3274-6.
    • (1990) Endocrinology , vol.126 , Issue.6 , pp. 3274-3276
    • Kleinberg, D.L.1    Ruan, W.2    Catanese, V.3    Newman, C.B.4    Feldman, M.5
  • 30
    • 0020267629 scopus 로고
    • Development of the mammary gland
    • Knight, C. H., and Peaker, M. (1982). Development of the mammary gland. J Reproduct Fertil 65(2), 521-36.
    • (1982) J Reproduct Fertil , vol.65 , Issue.2 , pp. 521-536
    • Knight, C.H.1    Peaker, M.2
  • 31
    • 84995948078 scopus 로고
    • Effects of testosterone propionate in immature and adult female rats
    • Laqueur, G. L., and Fluhmann, C. F. (1942). Effects of testosterone propionate in immature and adult female rats. Endocrinology 30, 93-101.
    • (1942) Endocrinology , vol.30 , pp. 93-101
    • Laqueur, G.L.1    Fluhmann, C.F.2
  • 32
    • 84995938221 scopus 로고
    • Mammary gland development with mammogen I in the castrated and the hypophysectomized rat
    • Lewis, A. A., Gomez, E. T., and Turner, C.W. (1942). Mammary gland development with mammogen I in the castrated and the hypophysectomized rat. Endocrinology 30, 34-47.
    • (1942) Endocrinology , vol.30 , pp. 34-47
    • Lewis, A.A.1    Gomez, E.T.2    Turner, C.W.3
  • 33
    • 0031016122 scopus 로고    scopus 로고
    • Rat prolactin synthesis by lactating mammary epithelial cells
    • Lkhider, M., Delpal, S., Le Provost, F., and Ollivier-Bousquet, M. (1997). Rat prolactin synthesis by lactating mammary epithelial cells. FEBS Lett 401(2-3), 117-22.
    • (1997) FEBS Lett , vol.401 , Issue.2-3 , pp. 117-122
    • Lkhider, M.1    Delpal, S.2    Le Provost, F.3    Ollivier-Bousquet, M.4
  • 34
    • 0017851258 scopus 로고
    • Correlation between the effects of neuroleptics on prolactin release, mammary stimulation and the vaginal cycle in rats
    • Lotz,W., and Krause, R. (1978). Correlation between the effects of neuroleptics on prolactin release, mammary stimulation and the vaginal cycle in rats. J Endocr 76, 507-15.
    • (1978) J Endocr , vol.76 , pp. 507-515
    • Lotz, W.1    Krause, R.2
  • 36
    • 0942274434 scopus 로고
    • Studies of the mammary gland II. The fetal development of the mammary gland in the female albino rat
    • Myers, J. A. (1917). Studies of the mammary gland II. The fetal development of the mammary gland in the female albino rat. Amer J Anat 22, 195-223.
    • (1917) Amer J Anat , vol.22 , pp. 195-223
    • Myers, J.A.1
  • 38
    • 26844497292 scopus 로고    scopus 로고
    • An in vivo battery for identifying endocrine modulators that are estrogenic or dopamine regulators
    • O'Connor, J. C., Cook, J. C., Craven, S. C., Van Pelt, C. S., and Obourn, J. D. (1996). An in vivo battery for identifying endocrine modulators that are estrogenic or dopamine regulators. Fund Appl Toxicol 33, 182-95.
    • (1996) Fund Appl Toxicol , vol.33 , pp. 182-195
    • O'Connor, J.C.1    Cook, J.C.2    Craven, S.C.3    Van Pelt, C.S.4    Obourn, J.D.5
  • 39
    • 0034071059 scopus 로고    scopus 로고
    • Evaluation of a Tier 1 screening battery for detecting endocrine-active compounds (EACs) using the positive controls testosterone, coumestrol, progesterone, and RU486
    • O'Connor, J. C., Davis, L. G., Frame, S. R., and Cook, J. C. (2000). Evaluation of a Tier 1 screening battery for detecting endocrine-active compounds (EACs) using the positive controls testosterone, coumestrol, progesterone, and RU486. Toxicol Sci 54, 338-54.
    • (2000) Toxicol Sci , vol.54 , pp. 338-354
    • O'Connor, J.C.1    Davis, L.G.2    Frame, S.R.3    Cook, J.C.4
  • 40
    • 0031719944 scopus 로고    scopus 로고
    • Sensitivity of a Tier I screening battery compared to an in utero exposure for detecting the estrogen receptor agonist 17 beta-estradiol
    • O'Connor, J. C., Frame, S. R., Biegel, L. B., Cook, J. C., and Davis, L. G. (1998). Sensitivity of a Tier I screening battery compared to an in utero exposure for detecting the estrogen receptor agonist 17 beta-estradiol. Toxicol Sci 44, 169-84.
    • (1998) Toxicol Sci , vol.44 , pp. 169-184
    • O'Connor, J.C.1    Frame, S.R.2    Biegel, L.B.3    Cook, J.C.4    Davis, L.G.5
  • 41
    • 0036738776 scopus 로고    scopus 로고
    • Evaluation of a 15-day screening assay using intact male rats for identifying steroid biosynthesis inhibitors and thyroid modulators
    • O'Connor, J. C., Frame, S. R., and Ladics, G. S. (2002). Evaluation of a 15-day screening assay using intact male rats for identifying steroid biosynthesis inhibitors and thyroid modulators. Toxicol Sci 69, 79-91.
    • (2002) Toxicol Sci , vol.69 , pp. 79-91
    • O'Connor, J.C.1    Frame, S.R.2    Ladics, G.S.3
  • 42
    • 0036740127 scopus 로고    scopus 로고
    • Evaluation of a 15-day screening assay using intact male rats identifying antiandrogens
    • O'Connor, J. C., Frame, S. R., and Ladics G. S. (2002). Evaluation of a 15-day screening assay using intact male rats identifying antiandrogens. Toxicol Sci 69, 92-108.
    • (2002) Toxicol Sci , vol.69 , pp. 92-108
    • O'Connor, J.C.1    Frame, S.R.2    Ladics, G.S.3
  • 43
    • 0015375692 scopus 로고
    • Is prolactin mitogenic for mammary epithelium?
    • Oka, T., and Topper, Y. J. (1972). Is prolactin mitogenic for mammary epithelium? Proc Natl Acad Sci USA 69(7), 1693-6.
    • (1972) Proc Natl Acad Sci USA , vol.69 , Issue.7 , pp. 1693-1696
    • Oka, T.1    Topper, Y.J.2
  • 44
    • 0014296372 scopus 로고
    • Prolactin activity of homogenous primate growth hormone preparations
    • Peckham,W. D., Hotchkiss, J., Knobil, E., and Nicoll, C. S. (1968). Prolactin activity of homogenous primate growth hormone preparations. Endocrinology 82, 1247.
    • (1968) Endocrinology , vol.82 , pp. 1247
    • Peckham, W.D.1    Hotchkiss, J.2    Knobil, E.3    Nicoll, C.S.4
  • 45
    • 0001252270 scopus 로고
    • Mammary gland development in the hypophysectomized albino rat
    • Reece, R. P., Turner, C.W., and Hill, R. T. (1936). Mammary gland development in the hypophysectomized albino rat. Proc Soc Exp Biol Med 34, 204-17.
    • (1936) Proc Soc Exp Biol Med , vol.34 , pp. 204-217
    • Reece, R.P.1    Turner, C.W.2    Hill, R.T.3
  • 46
    • 0032922633 scopus 로고    scopus 로고
    • The insulin-like growth factors (IGF) and IGF type I receptor during postnatal growth of the murine mammary gland: Sites of messenger ribonucleic acid expression and potential functions
    • Richert, M. M., andWood,T. L. (1999).The insulin-like growth factors (IGF) and IGF type I receptor during postnatal growth of the murine mammary gland: sites of messenger ribonucleic acid expression and potential functions. Endocrinology 140(1), 454-61.
    • (1999) Endocrinology , vol.140 , Issue.1 , pp. 454-461
    • Richert, M.M.1    andWood, T.L.2
  • 47
    • 0033303817 scopus 로고    scopus 로고
    • Insulin-like growth factor I is essential for terminal end bud formation and ductal morphogenesis during mammary development
    • Ruan,W., and Kleinberg, D. L. (1999). Insulin-like growth factor I is essential for terminal end bud formation and ductal morphogenesis during mammary development. Endocrinology 140(11), 5075-81.
    • (1999) Endocrinology , vol.140 , Issue.11 , pp. 5075-5081
    • Ruan, W.1    Kleinberg, D.L.2
  • 48
    • 14244261958 scopus 로고    scopus 로고
    • Progesterone stimulates mammary gland ductal morphogenesis by synergizing with and enhancing insulin-like growth factor-I action
    • Ruan,W., Monaco, M. E., and Kleinberg, D. L. (2005). Progesterone stimulates mammary gland ductal morphogenesis by synergizing with and enhancing insulin-like growth factor-I action. Endocrinology 146(3), 1170-8.
    • (2005) Endocrinology , vol.146 , Issue.3 , pp. 1170-1178
    • Ruan, W.1    Monaco, M.E.2    Kleinberg, D.L.3
  • 49
    • 0026472377 scopus 로고
    • Intact and aminoterminally shortened forms of insulin-like growth factor I induce mammary gland differentiation and development
    • Ruan, W., Newman, C. B, and Kleinberg, D. L. (1992). Intact and aminoterminally shortened forms of insulin-like growth factor I induce mammary gland differentiation and development. Proc Natl Acad Sci USA 89(22), 10872-6.
    • (1992) Proc Natl Acad Sci USA , vol.89 , Issue.22 , pp. 10872-10876
    • Ruan, W.1    Newman, C.B.2    Kleinberg, D.L.3
  • 50
    • 0028799676 scopus 로고
    • Estradiol enhances the stimulatory effect of insulin-like growth factor-I (IGF-I) on mammary development and growth hormone-induced IGF-I messenger ribonucleic acid
    • Ruan, W., Catanese, V., Wieczorek, R., Feldman, M., and Kleinberg, D. L. (1995). Estradiol enhances the stimulatory effect of insulin-like growth factor-I (IGF-I) on mammary development and growth hormone-induced IGF-I messenger ribonucleic acid. Endocrinology 136(3), 1296-302.
    • (1995) Endocrinology , vol.136 , Issue.3 , pp. 1296-1302
    • Ruan, W.1    Catanese, V.2    Wieczorek, R.3    Feldman, M.4    Kleinberg, D.L.5
  • 51
    • 0029911998 scopus 로고    scopus 로고
    • RU486-treated rats show endocrine and morphologic responses to therapies analogous to responses of women with polycystic ovary syndrome treated with similar therapies
    • Ruiz, A., Aguilar, R., Tebar, M., Gaytan, F., and Sanchez-Criado, J. E. (1996). RU486-treated rats show endocrine and morphologic responses to therapies analogous to responses of women with polycystic ovary syndrome treated with similar therapies. Biol Reprod 55, 1284-91.
    • (1996) Biol Reprod , vol.55 , pp. 1284-1291
    • Ruiz, A.1    Aguilar, R.2    Tebar, M.3    Gaytan, F.4    Sanchez-Criado, J.E.5
  • 52
    • 31544453619 scopus 로고    scopus 로고
    • Androgen dependent mammary gland virilism in rats given the selective estrogen receptor modulator LY2066948 hydrochloride
    • Rudmann, D. G., Cohen, I. R., Robbins, M. R., Coutant, D. E., and Henck, J. W. (2005). Androgen dependent mammary gland virilism in rats given the selective estrogen receptor modulator LY2066948 hydrochloride. Toxicol Pathol 33(6), 711-19.
    • (2005) Toxicol Pathol , vol.33 , Issue.6 , pp. 711-719
    • Rudmann, D.G.1    Cohen, I.R.2    Robbins, M.R.3    Coutant, D.E.4    Henck, J.W.5
  • 53
    • 33847792932 scopus 로고
    • Asynchronous development of the rat mammary glands: A determining factor in carcinogenesis
    • Russo, I. H., Pokorzynski, T., and Russo, J. (1986). Asynchronous development of the rat mammary glands: a determining factor in carcinogenesis. Breast Cancer Res Treat 8, 118a.
    • (1986) Breast Cancer Res Treat , vol.8
    • Russo, I.H.1    Pokorzynski, T.2    Russo, J.3
  • 54
    • 0024550327 scopus 로고
    • Effect of medoxyprogesterone acetate on the response of the rat mammary gland to carcinogenesis
    • Russo, I. H., Gimotty, P., Dupuis, M., and Russo, J. (1989a). Effect of medoxyprogesterone acetate on the response of the rat mammary gland to carcinogenesis. Brit J Canc 59(2), 210-16.
    • (1989) Brit J Canc , vol.59 , Issue.2 , pp. 210-216
    • Russo, I.H.1    Gimotty, P.2    Dupuis, M.3    Russo, J.4
  • 55
    • 0000026239 scopus 로고
    • Endocrine Influences on the Mammary Gland
    • T. C. Jones, U. Mohr, and R. D. Hunt, eds, p, Springer-Verlag, Berlin
    • Russo, I. H., Medado, J., and Russo, J. (1989b). Endocrine Influences on the Mammary Gland. In: Monographs on Pathology of Laboratory Animals (T. C. Jones, U. Mohr, and R. D. Hunt, eds), p. 33, Springer-Verlag, Berlin.
    • (1989) Monographs on Pathology of Laboratory Animals , pp. 33
    • Russo, I.H.1    Medado, J.2    Russo, J.3
  • 56
    • 0000026239 scopus 로고
    • Morphology and development of the rat mammary gland
    • T. C. Jones, U. Mohr, and R. D. Hunt, eds, p, Springer-Verlag, Berlin
    • Russo, I. H., Tewari, M., and Russo, J. (1989c). Morphology and development of the rat mammary gland. In: Monographs on Pathology of Laboratory Animals (T. C. Jones, U. Mohr, and R. D. Hunt, eds.), p. 233, Springer-Verlag, Berlin.
    • (1989) Monographs on Pathology of Laboratory Animals , pp. 233
    • Russo, I.H.1    Tewari, M.2    Russo, J.3
  • 58
    • 0032617256 scopus 로고    scopus 로고
    • Progesterone signaling and mammary gland morphogenesis
    • Shyamala, G. (1999). Progesterone signaling and mammary gland morphogenesis. J Mamm Gland Biol Neoplasia 4(1), 89-104.
    • (1999) J Mamm Gland Biol Neoplasia , vol.4 , Issue.1 , pp. 89-104
    • Shyamala, G.1
  • 59
    • 0032737330 scopus 로고    scopus 로고
    • The progesterone receptor and its isoforms in mammary development
    • Shyamala, G., Louie, S. G., Camarillo, I. G., and Talamantes, F. (1999). The progesterone receptor and its isoforms in mammary development. Mol Genet Metabol 68(2), 182-90.
    • (1999) Mol Genet Metabol , vol.68 , Issue.2 , pp. 182-190
    • Shyamala, G.1    Louie, S.G.2    Camarillo, I.G.3    Talamantes, F.4
  • 60
    • 0035863007 scopus 로고    scopus 로고
    • Postnatal mammary gland morphogenesis
    • Silberstein, G. B. (2001). Postnatal mammary gland morphogenesis. Microsc Res Techn 52(2), 155-62.
    • (2001) Microsc Res Techn , vol.52 , Issue.2 , pp. 155-162
    • Silberstein, G.B.1
  • 61
    • 0031765774 scopus 로고    scopus 로고
    • Almost exclusive androgenic action of dehydroepiandrosterone in the rat mammary gland
    • Sourla, A., Martel, C., Labrie, C., and Labrie, F. (1998). Almost exclusive androgenic action of dehydroepiandrosterone in the rat mammary gland. Endocrinology 139(2), 753-64.
    • (1998) Endocrinology , vol.139 , Issue.2 , pp. 753-764
    • Sourla, A.1    Martel, C.2    Labrie, C.3    Labrie, F.4
  • 62
    • 0032146528 scopus 로고    scopus 로고
    • Effect of dehydroepiandrosterone on vaginal and uterine histomorphology in the rat
    • Sourla, A., Flamand, M., Belanger, A., and Labrie, F. (1998). Effect of dehydroepiandrosterone on vaginal and uterine histomorphology in the rat. J Steroid Biochem Mol Biol 66(3), 137-49.
    • (1998) J Steroid Biochem Mol Biol , vol.66 , Issue.3 , pp. 137-149
    • Sourla, A.1    Flamand, M.2    Belanger, A.3    Labrie, F.4
  • 63
    • 0019074917 scopus 로고
    • Multiple hormone interactions in the developmental biology of the mammary gland
    • Topper, Y. J., and Freeman, C. S. (1980). Multiple hormone interactions in the developmental biology of the mammary gland. Physiol Rev 60(4), 1049-106.
    • (1980) Physiol Rev , vol.60 , Issue.4 , pp. 1049-1106
    • Topper, Y.J.1    Freeman, C.S.2
  • 64
    • 0015420944 scopus 로고
    • Some aspects of mouse mammary gland development from maturity to early pregnancy
    • Topper, Y. J., Oka, T., Owens, I. S., and Vonderhaar, B. K. (1972). Some aspects of mouse mammary gland development from maturity to early pregnancy. In Vitro 8(3), 228-36.
    • (1972) In Vitro , vol.8 , Issue.3 , pp. 228-236
    • Topper, Y.J.1    Oka, T.2    Owens, I.S.3    Vonderhaar, B.K.4
  • 65
    • 0034075395 scopus 로고    scopus 로고
    • Repeated dose (28 days) oral toxicity study of flutamide in rats, based on the draft protocol for the 'Enhanced OECD Test Guideline 407' for screening endocrine-disrupting chemicals
    • Toyoda, K., Shibutani, M., Tamura, T., Koujitani, T., Uneyama, C., and Hirose, M. (2000). Repeated dose (28 days) oral toxicity study of flutamide in rats, based on the draft protocol for the 'Enhanced OECD Test Guideline 407' for screening endocrine-disrupting chemicals. Arch Toxicol 74, 127-32.
    • (2000) Arch Toxicol , vol.74 , pp. 127-132
    • Toyoda, K.1    Shibutani, M.2    Tamura, T.3    Koujitani, T.4    Uneyama, C.5    Hirose, M.6
  • 66
    • 0023628955 scopus 로고
    • Effects of the progesterone antagonist RU486 on ovarian activity in the rat
    • Van Der Schoot, P., Bakker, G. H., and Klijn, J. G. M. (1987). Effects of the progesterone antagonist RU486 on ovarian activity in the rat. Endocrinology 121, 1375-82.
    • (1987) Endocrinology , vol.121 , pp. 1375-1382
    • Van Der Schoot, P.1    Bakker, G.H.2    Klijn, J.G.M.3
  • 67
    • 33645889363 scopus 로고    scopus 로고
    • Altered mammary gland development in male rats exposed to genistein and methoxychlor
    • Wang, X. J., Bartolucci-Page, E., Fenton, S. E., and You, L. (2005). Altered mammary gland development in male rats exposed to genistein and methoxychlor. Toxicol Sci 91, 93-103.
    • (2005) Toxicol Sci , vol.91 , pp. 93-103
    • Wang, X.J.1    Bartolucci-Page, E.2    Fenton, S.E.3    You, L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.