Hepatoprotective effect of stem of Musa sapientum Linn in rats intoxicated with carbon tetrachloride

Annals of Hepatology

Volumn 10, Issue 3, 2011, Pages 333-339

  Dikshit, Piyush ^a   Tyagi, Mool Kumar ^a   Shukla, Kirtikar ^a   Sharma, Sonal ^a   Gambhir, Jasvindar Kaur ^a   Shukla, Rimi ^a  

^a UNIVERSITY COLLEGE OF MEDICAL SCIENCES   (India)

Author keywords

Antioxidant property; Aqueous extract; Hepatic functions; Histomorphology; Silymarin

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; CARBON TETRACHLORIDE; GLUTATHIONE; LIVER PROTECTIVE AGENT; MALONALDEHYDE; MUSA SAPIENTUM EXTRACT; PLANT EXTRACT; SILYMARIN; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BANANA; CONTROLLED STUDY; DRUG DOSE COMPARISON; HISTOPATHOLOGY; LIPID PEROXIDATION; LIVER PROTECTION; LIVER TOXICITY; MALE; MUSA SAPIENTUM; NONHUMAN; OXIDATIVE STRESS; PLANT STEM; RAT;

EID: 79959427558     PISSN: 16652681     EISSN: None     Source Type: Journal    
DOI: 10.1016/s1665-2681(19)31546-7     Document Type: Article

References (35)

1. Luper SND. A review of plants used in the treatment of liver disease: Part 1. Alt Med Rev 1998; 3: 410-21.
2. Ram VJ. Herbal preparations as a source of hepatotoprotective agents. Drug News Perspec 2001; 14: 353-63.
3. Thyagarajan S, Jayaram S, Gopalkrishnan V, Hari R, Jeya KP, Sripathi M. Herbal medicines for liver diseases in India. J Gastroenterol Hepatol 2002; 3: 370-6.
4. Bisset NG (eds.). Herbal drugs and phytopharmaceuticals. A handbook for practice on a specific basis. Sttutgart: Medpharm Scientific; 1994, p. 302-14.
5. Smitha K, Sujatha KS, George S. Hypolipidemic and antioxidant effects of fruits of Musa AAA (Chenkadali) in alloxan induced diabetic rats. Ind J Exp Biol 2010; 48: 165-73.
6. Mallick C, Malti R, Gosh D. Antidiabetogenic effects of separate and composite extract of seed of Jamuna (Euglena jambolana) and root of "kadali" (Musa paradisiaca) in streptozotocin-induced diabetic male albino rats. Int J Pharmacol (PAK) 2006; 5: 492-53.
7. Kailash P, Bharathi K, Srinivasan K. Evaluation of Musa (paradisiaca Linn. Cultivar) "Puttubale" stem aqueous extract for antilithiatic activity in albino rats. Ind J Physiol Pharmacol 1993; 37: 337-41.
8. Ross IA. World medicinal plants & chemical constituents and medicinal uses. New Jersy: Humana Press; 2000, p. 319-26.
9. Borges MH, Alves DLF, Raslan DS, Veleso PS, Rodrigues VM, Brandeburgo MIH, Limad ME. Neutralizing properties of Musa paradisiaca L (musacae) aqueous extract on phospholipase A2 and lethal activities of crotalidae venoms. J Ethnopharmacol 2005; 98: 21-9.
10. Ingale SP, Ingale PL, Joshi AM. To study analgesic activity of stem of Musa sapientum linn. J Pharm Res 2009; 2: 1381-2.
11. Waalkes TP, Sjoerdsma A, Creveling CR, Weissbach H, Udenfriend S. Serotonin, Norepinephrine and related compounds in banana. Science 1958; 127: 648-53.
12. Pari L, Uma MJ. Hypoglycemic effect of Musa sapientum L. in alloxan induced diabetic rats. J Ethanopharmacol 1999; 68: 321-5.
13. Knapp FF, Nicholas HJ. The sterols and triterpenes of banana pulp. J Food Sci 1969; 34: 584-6.
14. Krishna MG, Pallavi E, Ravi KB, Ramesh M, Venkatesh S. Hepatoprotective activity of Ficus carica (Linn) leaf extract against carbon tetrachloride-induced hepato-toxicity in rats. DARU 2007; 15: 162-7.
15. Harborne JB. Phytochemical methods. London: Chapman and Hall; 1973, p. 49-188.
16. McDonald S, Prenzler PD, Autolovich M, Robards K. Phenolic content and antioxidant activity of olive extracts. Food Chem 2001; 73: 73-84.
17. Thirupathi K, Satish KS, Govardhan P, Ravi KB, RamaKrishna D, Krishna MG. Protective effect of Momordica dioica, against hepatic damage caused by carbon tetrachloride in rats. Act Pharm Sci 2006; 48: 213-2.
18. Satoh K. Serum lipid peroxide in cerebrospinal disorder by a new colorimetric method. Clin Chim Act 1978; 90: 37-43.
19. Beutler E, Duron D, Kelly BM. Improved method for the determination of blood glutathione. In: Dacie JV, Lewis SM (eds.). Practical Hematology. 1974, p. 501-3.
20. Nandi A, Chatterjee IB. Assay of superoxide dismutase activity in animal tissue. J Biol Sci 1988; 13: 305-15.
21. Balderas RI, Camacho CMR, Carranza RP, Lozano GHG, Castillo ND, Alvarez M. Hepatoprotective effect of Leucophyllum frutescens on wistar albino rats intoxicated with carbon tetrachloride. Ann Hepatol 2007; 6: 251-4.
22. Lutz WD, Meinrad B, Andrease S. Hepatotoxicity and mechanism of action of haloalkanes: Carbon tetrachloride as a toxicological model. Crit Rev Toxicol 2003; 33: 105-36.
23. Reynolds ES. Liver parenchymal cell injury. Initial alteration of the cell following poisoning with carbon tetrachloride. J Cell Biol 1963; 19: 139-57.
24. Omolola AA, Ebenezer OF. Hepatoprotective effects of Vernonia amygdalina (astereaceae) in rats treated with carbon tetrachloride. Exp Toxicol Pathol 2010; 62: 197-206.
25. Hui ML, Hsien CT, Chau W, Jin L, Chia L, Fen PC. Hepatoprotective effects of Solanum nigrum Linn extract against CCl4-induced oxidative damage in rats. Chem Biol Interactions 2008; 171: 283-93.
26. Recknagel RO. Carbon tetrachloride hepatotoxicity: status quo and future prospects. Trends Pharmacol Sci 1983; 4: 129-31.
27. Recknagel RO, Glende EA, Dolak JA, Waller RL. Mechanism of carbon tetrachloride toxicity. Pharmacol Ther 1989; 43: 139-54.
28. Houzi D, Lekehal M, Moreau A, Moulis C, Feldmann G, Robin MA, et al. Cytochrome P450-generated reactive metabolite cause mitochondrial permeability transition, caspase activation and apoptosis in rat. Hepatology 2000; 32: 303-11.
29. Nicotera P, Bellomo G, Orrenius S. Calcium- mediated mechanism in chemically induced cell death. Annu Rev Pharmacol Toxicol 1992; 32: 449-70.
30. Neetu S, Sangeeta S. Hepatoprotective potential of aqueous extract of Butea monosperma against CCl4 induced damage rats. Exp Toxicol Pathol 2010. Doi: 10.1016/ j.etp.2010.05.009.
31. Pramod K, Deval RG, Lakshmayy A, Ramachandra SS. Antioxidant and hepatoprotective activity of tubers of Momordica tuberosa against CCl4 induced liver injury in rats. Indian J Exp Biol 2008; 46: 510-3.
32. Basosio E, Benelli C, Pirola O. Effect of the flavanolignans of Silybum marianum L on lipid peroxidation in rat liver microsomes and freshly isolated hepatocytes. Pharmacol Res 1992; 25: 147-54.
33. Oh H, Kim DH, Cho JH, Kim YC. Hepatoprotective and free radical scavenging activities of phenolic petrosins and flavonoids isolated from Equisetum arvense. J Ethnopharmacol 2004; 95: 421-4.
34. Yoshikawa M, Morikawa T, Kashima Y, Ninomiya K, Matsuda H. Structure of new dammarane-type triterpene saponins from the flower buds of Panax notoginseng and hepatoprotective effects of principal ginseng sap saponin. J Nat Prod 2003; 66: 922-34.
35. Shukla R, Gupta S, Gambhir JK, Murthy PS. Antioxidant effect of aqueous extract of the bark of Ficus bengalensis in hypercholesterolemic rabbits. J Ethnopharmacol 2004; 92: 47-51.