메뉴 건너뛰기




Volumn 152, Issue 7, 2011, Pages 2580-2588

Gastrin treatment stimulates β-cell regeneration and improves glucose tolerance in 95% pancreatectomized rats

Author keywords

[No Author keywords available]

Indexed keywords

GASTRIN 17; GASTRIN RECEPTOR; TRANSCRIPTION FACTOR PDX 1;

EID: 79959407993     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2011-0066     Document Type: Article
Times cited : (41)

References (51)
  • 1
    • 0037219411 scopus 로고    scopus 로고
    • β-cell deficit and increased β-cell apoptosis in humans with type 2 diabetes
    • DOI 10.2337/diabetes.52.1.102
    • Butler AE, Janson J, Bonner-Weir S, Ritzel R, Rizza RA, Butler PC 2003 β-Cell deficit and increased β-cell apoptosis in humans with type 2 diabetes. Diabetes 52:102-110 (Pubitemid 36042113)
    • (2003) Diabetes , vol.52 , Issue.1 , pp. 102-110
    • Butler, A.E.1    Janson, J.2    Bonner-Weir, S.3    Ritzel, R.4    Rizza, R.A.5    Butler, P.C.6
  • 3
    • 4644225789 scopus 로고    scopus 로고
    • Islet- And stem-cell-based tissue engineering in diabetes
    • DOI 10.1016/j.copbio.2004.08.011, PII S095816690400117X
    • Montanya E 2004 Islet- and stem-cell-based tissue engineering in diabetes. Curr Opin Biotechnol 15:435-440 (Pubitemid 39304040)
    • (2004) Current Opinion in Biotechnology , vol.15 , Issue.5 , pp. 435-440
    • Montanya, E.1
  • 5
    • 0026533924 scopus 로고
    • Pharmacological and biochemical characterization of cholecystokinin/ gastrin receptors in developing rat pancreas. Age-related expression of distinct receptor glycoforms
    • Hadjiivanova C, Dufresne M, Poirot S, Sozzani P, Vaysse N, Moroder L, Fourmy D 1992 Pharmacological and biochemical characterization of cholecystokinin/gastrin receptors in developing rat pancreas. Age-related expression of distinct receptor glycoforms. Eur J Biochem 204:273-279
    • (1992) Eur J Biochem , vol.204 , pp. 273-279
    • Hadjiivanova, C.1    Dufresne, M.2    Poirot, S.3    Sozzani, P.4    Vaysse, N.5    Moroder, L.6    Fourmy, D.7
  • 6
    • 0029944459 scopus 로고    scopus 로고
    • Islet cell neogenesis in the pancreas
    • Bouwens L, Klöppel G 1996 Islet cell neogenesis in the pancreas. Virchows Arch 427:553-560 (Pubitemid 26109205)
    • (1996) Virchows Archiv , vol.427 , Issue.6 , pp. 553-560
    • Bouwens, L.1    Kloppel, G.2
  • 7
    • 58149357117 scopus 로고    scopus 로고
    • Combination therapy with glucagon-like peptide-1 and gastrin restores normoglycemia in diabetic NOD mice
    • Suarez-Pinzon WL, Power RF, Yan Y, Wasserfall C, Atkinson M, Rabinovitch A 2008 Combination therapy with glucagon-like peptide-1 and gastrin restores normoglycemia in diabetic NOD mice. Diabetes 57:3281-3288
    • (2008) Diabetes , vol.57 , pp. 3281-3288
    • Suarez-Pinzon, W.L.1    Power, R.F.2    Yan, Y.3    Wasserfall, C.4    Atkinson, M.5    Rabinovitch, A.6
  • 8
    • 24144446405 scopus 로고    scopus 로고
    • Combination therapy with epidermal growth factor and gastrin increases β-cell mass and reverses hyperglycemia in diabetic NOD mice
    • DOI 10.2337/diabetes.54.9.2596
    • Suarez-Pinzon WL, Yan Y, Power R, Brand SJ, Rabinovitch A 2005 Combination therapy with epidermal growth factor and gastrin increases β-cell mass and reverses hyperglycemia in diabetic NOD mice. Diabetes 54:2596-2601 (Pubitemid 41233580)
    • (2005) Diabetes , vol.54 , Issue.9 , pp. 2596-2601
    • Suarez-Pinzon, W.L.1    Yan, Y.2    Power, R.3    Brand, S.J.4    Rabinovitch, A.5
  • 9
    • 21244441973 scopus 로고    scopus 로고
    • Combination therapy with epidermal growth factor and gastrin induces neogenesis of human islet β-cells from pancreatic duct cells and an increase in functional β-cell mass
    • DOI 10.1210/jc.2004-0761
    • Suarez-Pinzon WL, Lakey JR, Brand SJ, Rabinovitch A 2005 Combination therapy with epidermal growth factor and gastrin induces neogenesis of human islet β-cells from pancreatic duct cells and an increase in functional β-cell mass. J Clin Endocrinol Metab 90:3401-3409 (Pubitemid 41014304)
    • (2005) Journal of Clinical Endocrinology and Metabolism , vol.90 , Issue.6 , pp. 3401-3409
    • Suarez-Pinzon, W.L.1    Lakey, J.R.T.2    Brand, S.J.3    Rabinovitch, A.4
  • 10
    • 1542284736 scopus 로고    scopus 로고
    • Combined gastrin and epidermal growth factor treatment induces islet regeneration and restores normoglycaemia in C57BI6/J mice treated with alloxan
    • DOI 10.1007/s00125-003-1287-1
    • Rooman I, Bouwens L 2004 Combined gastrin and epidermal growth factor treatment induces islet regeneration and restores normoglycaemia in C57Bl6/J mice treated with alloxan. Diabetologia 47:259-265 (Pubitemid 38315362)
    • (2004) Diabetologia , vol.47 , Issue.2 , pp. 259-265
    • Rooman, I.1    Bouwens, L.2
  • 11
    • 0036310118 scopus 로고    scopus 로고
    • Gastrin stimulates β-cell neogenesis and increases islet mass from transdifferentiated but not from normal exocrine pancreas tissue
    • Rooman I, Lardon J, Bouwens L 2002 Gastrin stimulates β-cell neogenesis and increases islet mass from transdifferentiated but not from normal exocrine pancreas tissue. Diabetes 51:686-690 (Pubitemid 34760176)
    • (2002) Diabetes , vol.51 , Issue.3 , pp. 686-690
    • Rooman, I.1    Lardon, J.2    Bouwens, L.3
  • 12
    • 53749089728 scopus 로고    scopus 로고
    • Combination therapy with glucagon-like peptide-1 and gastrin induces β-cell neogenesis from pancreatic duct cells in human islets transplanted in immunodeficient diabetic mice
    • Suarez-Pinzon WL, Lakey JR, Rabinovitch A 2008 Combination therapy with glucagon-like peptide-1 and gastrin induces β-cell neogenesis from pancreatic duct cells in human islets transplanted in immunodeficient diabetic mice. Cell Transplant 17:631-640
    • (2008) Cell Transplant , vol.17 , pp. 631-640
    • Suarez-Pinzon, W.L.1    Lakey, J.R.2    Rabinovitch, A.3
  • 13
    • 0028330011 scopus 로고
    • Transplanted β-cell response to increased metabolic demand. Changes in β-cell replication and mass
    • Montaña E, Bonner-Weir S, Weir GC 1994 Transplanted β-cell response to increased metabolic demand. Changes in β-cell replication and mass. J Clin Invest 93:1577-1582
    • (1994) J Clin Invest , vol.93 , pp. 1577-1582
    • Montaña, E.1    Bonner-Weir, S.2    Weir, G.C.3
  • 14
    • 73349120953 scopus 로고    scopus 로고
    • Pancreatic remodeling: β-cell apoptosis, proliferation and neogenesis, and the measurement of β-cell mass and of individual β-cell size
    • Montanya E, Téllez N 2009 Pancreatic remodeling: β-cell apoptosis, proliferation and neogenesis, and the measurement of β-cell mass and of individual β-cell size. Methods Mol Biol 560:137-158
    • (2009) Methods Mol Biol , vol.560 , pp. 137-158
    • Montanya, E.1    Téllez, N.2
  • 17
    • 0034775035 scopus 로고    scopus 로고
    • Pancreatic duodenal homeobox-1, PDX-1, a major regulator of beta cell identity and function
    • DOI 10.1007/s001250100628
    • McKinnon CM, Docherty K 2001 Pancreatic duodenal homeobox-1, PDX-1, a major regulator of β cell identity and function. Diabetologia 44:1203-1214 (Pubitemid 33010496)
    • (2001) Diabetologia , vol.44 , Issue.10 , pp. 1203-1214
    • McKinnon, C.M.1    Docherty, K.2
  • 18
    • 33847691583 scopus 로고    scopus 로고
    • Expression of transcription factors and precursor cell markers during regeneration of β cells in pancreata of rats treated with streptozotocin
    • DOI 10.1007/s00428-006-0349-4
    • Tiemann K, Panienka R, Klöppel G 2007 Expression of transcription factors and precursor cell markers during regeneration of β cells in pancreata of rats treated with streptozotocin. Virchows Arch 450:261-266 (Pubitemid 46376556)
    • (2007) Virchows Archiv , vol.450 , Issue.3 , pp. 261-266
    • Tiemann, K.1    Panienka, R.2    Kloppel, G.3
  • 19
    • 0033911990 scopus 로고    scopus 로고
    • Modulation of rat pancreatic acinoductal transdifferentiation and expression of PDX-1 in vitro
    • Rooman I, Heremans Y, Heimberg H, Bouwens L 2000 Modulation of rat pancreatic acinoductal transdifferentiation and expression of PDX-1 in vitro. Diabetologia 43:907-914 (Pubitemid 30463171)
    • (2000) Diabetologia , vol.43 , Issue.7 , pp. 907-914
    • Rooman, I.1    Heremans, Y.2    Heimberg, H.3    Bouwens, L.4
  • 21
    • 33846826610 scopus 로고    scopus 로고
    • Adenoviral overproduction of interleukin-1 receptor antagonist increases beta cell replication and mass in syngeneically transplanted islets, and improves metabolic outcome
    • DOI 10.1007/s00125-006-0548-1
    • Téllez N, Montolio M, Estil-les E, Escoriza J, Soler J, Montanya E 2007 Adenoviral overproduction of interleukin-1 receptor antagonist increases β-cell replication and mass in syngeneically transplanted islets, and improves metabolic outcome. Diabetologia 50:602-611 (Pubitemid 46215504)
    • (2007) Diabetologia , vol.50 , Issue.3 , pp. 602-611
    • Tellez, N.1    Montolio, M.2    Estilles, E.3    Escoriza, J.4    Soler, J.5    Montanya, E.6
  • 22
    • 0029907967 scopus 로고    scopus 로고
    • β-Cell growth and mass are preserved in long-term syngeneic islet transplantation in streptozocin-induced diabetic Lewis rats
    • Nácher V, Raurell M, Merino JF, Aranda O, Soler J, Montana E 1996 β-Cell growth and mass are preserved in long-term syngeneic islet transplantation in streptozocin-induced diabetic Lewis rats. Diabetes 45:1541-1546 (Pubitemid 26357547)
    • (1996) Diabetes , vol.45 , Issue.11 , pp. 1541-1546
    • Nacher, V.1    Raurell, M.2    Merino, J.F.3    Aranda, O.4    Soler, J.5    Montana, E.6
  • 23
    • 0036097472 scopus 로고    scopus 로고
    • β-cell death and mass in syngeneically transplanted islets exposed to short- And long-term hyperglycemia
    • Biarnés M, Montolio M, Nacher V, Raurell M, Soler J, Montanya E 2002 β-Cell death and mass in syngeneically transplanted islets exposed to short- and long-term hyperglycemia. Diabetes 51:66-72 (Pubitemid 34517981)
    • (2002) Diabetes , vol.51 , Issue.1 , pp. 66-72
    • Biarnes, M.1    Montolio, M.2    Nacher, V.3    Raurell, M.4    Soler, J.5    Montanya, E.6
  • 24
    • 0037931407 scopus 로고    scopus 로고
    • Differentiation and proliferation of endocrine cells in the regenerating rat pancreas after 90% pancreatectomy
    • DOI 10.1679/aohc.66.163
    • Hayashi KY, Tamaki H, Handa K, Takahashi T, Kakita A, Yamashina S 2003 Differentiation and proliferation of endocrine cells in the regenerating rat pancreas after 90% pancreatectomy. Arch Histol Cytol 66:163-174 (Pubitemid 36834425)
    • (2003) Archives of Histology and Cytology , vol.66 , Issue.2 , pp. 163-174
    • Hayashi, K.Y.1    Tamaki, H.2    Handa, K.3    Takahashi, T.4    Kakita, A.5    Yamashina, S.6
  • 25
    • 0020636495 scopus 로고
    • Partial pancreatectomy in the rat and subsequent defect in glucose-induced insulin release
    • Bonner-Weir S, Trent DF, Weir GC 1983 Partial pancreatectomy in the rat and subsequent defect in glucose-induced insulin release. J Clin Invest 71:1544-1553 (Pubitemid 13056759)
    • (1983) Journal of Clinical Investigation , vol.71 , Issue.6 , pp. 1544-1553
    • Bonner, W.S.1    Trent, D.F.2    Weir, G.C.3
  • 26
    • 0027449197 scopus 로고
    • A second pathway for regeneration of adult exocrine and endocrine pancreas. A possible recapitulation of embryonic development
    • Bonner-Weir S, Baxter LA, Schuppin GT, Smith FE 1993 A second pathway for regeneration of adult exocrine and endocrine pancreas. A possible recapitulation of embryonic development. Diabetes 42:1715-1720
    • (1993) Diabetes , vol.42 , pp. 1715-1720
    • Bonner-Weir, S.1    Baxter, L.A.2    Schuppin, G.T.3    Smith, F.E.4
  • 27
    • 0023887393 scopus 로고
    • Differential gastrin gene expression in rat gastrointestinal tract and pancreas during neonatal development
    • Brand SJ, Fuller PJ 1988 Differential gastrin gene expression in rat gastrointestinal tract and pancreas during neonatal development. J Biol Chem 263:5341-5347
    • (1988) J Biol Chem , vol.263 , pp. 5341-5347
    • Brand, S.J.1    Fuller, P.J.2
  • 32
    • 84961017335 scopus 로고
    • Primary peptic ulcerations of the jejunum associated with islet cell tumors of the pancreas
    • discussion, 724-728
    • Zollinger RM, Ellison EH 1955 Primary peptic ulcerations of the jejunum associated with islet cell tumors of the pancreas. Ann Surg 142:709-723; discussion, 724-728
    • (1955) Ann Surg , vol.142 , pp. 709-723
    • Zollinger, R.M.1    Ellison, E.H.2
  • 33
    • 0016442930 scopus 로고
    • Pathomorphologic, biochemical, and diagnostic aspects of gastrinomas (Zollinger-Ellison syndrome)
    • Creutzfeldt W, Arnold R, Creutzfeldt C, Track NS 1975 Pathomorphologic, biochemical, and diagnostic aspects of gastrinomas (Zollinger-Ellison syndrome). Hum Pathol 6:47-76
    • (1975) Hum Pathol , vol.6 , pp. 47-76
    • Creutzfeldt, W.1    Arnold, R.2    Creutzfeldt, C.3    Track, N.S.4
  • 34
    • 33749428116 scopus 로고    scopus 로고
    • Increased islet beta cell replication adjacent to intrapancreatic gastrinomas in humans
    • DOI 10.1007/s00125-006-0410-5
    • Meier JJ, Butler AE, Galasso R, Rizza RA, Butler PC 2006 Increased islet β cell replication adjacent to intrapancreatic gastrinomas in humans. Diabetologia 49:2689-2696 (Pubitemid 44510793)
    • (2006) Diabetologia , vol.49 , Issue.11 , pp. 2689-2696
    • Meier, J.J.1    Butler, A.E.2    Galasso, R.3    Rizza, R.A.4    Butler, P.C.5
  • 35
    • 66649084335 scopus 로고    scopus 로고
    • Age-dependent decline in β-cell proliferation restricts the capacity of β-cell regeneration in mice
    • Tschen SI, Dhawan S, Gurlo T, Bhushan A 2009 Age-dependent decline in β-cell proliferation restricts the capacity of β-cell regeneration in mice. Diabetes 58:1312-1320
    • (2009) Diabetes , vol.58 , pp. 1312-1320
    • Tschen, S.I.1    Dhawan, S.2    Gurlo, T.3    Bhushan, A.4
  • 36
    • 0033867213 scopus 로고    scopus 로고
    • Linear correlation between β-cell mass and body weight throughout the lifespan in Lewis rats. Role of β-cell hyperplasia and hypertrophy
    • Montanya E, Nacher V, Biarnés M, Soler J 2000 Linear correlation between β-cell mass and body weight throughout the lifespan in Lewis rats: role of β-cell hyperplasia and hypertrophy. Diabetes 49:1341-1346 (Pubitemid 30624235)
    • (2000) Diabetes , vol.49 , Issue.8 , pp. 1341-1346
    • Montanya, E.1    Nacher, V.2    Biarnes, M.3    Soler, J.4
  • 37
    • 66649128739 scopus 로고    scopus 로고
    • Adaptive β-cell proliferation is severely restricted with advanced age
    • Rankin MM, Kushner JA 2009 Adaptive β-cell proliferation is severely restricted with advanced age. Diabetes 58:1365-1372
    • (2009) Diabetes , vol.58 , pp. 1365-1372
    • Rankin, M.M.1    Kushner, J.A.2
  • 40
  • 41
    • 33644841711 scopus 로고    scopus 로고
    • Cholecystokinin and gastrin receptors
    • DOI 10.1152/physrev.00014.2005
    • Dufresne M, Seva C, Fourmy D 2006 Cholecystokinin and gastrin receptors. Physiol Rev 86:805-847 (Pubitemid 44033383)
    • (2006) Physiological Reviews , vol.86 , Issue.3 , pp. 805-847
    • Dufresne, M.1    Seva, C.2    Fourmy, D.3
  • 42
    • 0034100823 scopus 로고    scopus 로고
    • Reversal of insulin-dependent diabetes using islets generated in vitro from pancreatic stem cells
    • DOI 10.1038/73128
    • Ramiya VK, Maraist M, Arfors KE, Schatz DA, Peck AB, Cornelius JG 2000 Reversal of insulin-dependent diabetes using islets generated in vitro from pancreatic stem cells. Nat Med 6:278-282 (Pubitemid 30148619)
    • (2000) Nature Medicine , vol.6 , Issue.3 , pp. 278-282
    • Ramiya, V.K.1    Maraist, M.2    Arfors, K.E.3    Schatz, D.A.4    Peck, A.B.5    Cornelius, J.G.6
  • 43
    • 34347384162 scopus 로고    scopus 로고
    • Differentiation of affinity-purified human pancreatic duct cells to β-cells
    • DOI 10.2337/db06-1670
    • Yatoh S, Dodge R, Akashi T, Omer A, Sharma A, Weir GC, Bonner-Weir S 2007 Differentiation of affinity-purified human pancreatic duct cells to β-cells. Diabetes 56:1802-1809 (Pubitemid 47025448)
    • (2007) Diabetes , vol.56 , Issue.7 , pp. 1802-1809
    • Yatoh, S.1    Dodge, R.2    Akashi, T.3    Omer, A.4    Sharma, A.5    Weir, G.C.6    Bonner-Weir, S.7
  • 44
    • 0031841517 scopus 로고    scopus 로고
    • Extra-insular beta cells associated with ductules are frequent in adult human pancreas
    • DOI 10.1007/s001250050960
    • Bouwens L, Pipeleers DG 1998 Extra-insular β cells associated with ductules are frequent in adult human pancreas. Diabetologia 41:629-633 (Pubitemid 28261395)
    • (1998) Diabetologia , vol.41 , Issue.6 , pp. 629-633
    • Bouwens, L.1    Pipeleers, D.G.2
  • 45
    • 0034793740 scopus 로고    scopus 로고
    • Mitogenic effect of gastrin and expression of gastrin receptors in duct-like cells of rat pancreas
    • Rooman I, Lardon J, Flamez D, Schuit F, Bouwens L 2001 Mitogenic effect of gastrin and expression of gastrin receptors in duct-like cells of rat pancreas. Gastroenterology 121:940-949 (Pubitemid 32959403)
    • (2001) Gastroenterology , vol.121 , Issue.4 , pp. 940-949
    • Rooman, I.1    Lardon, J.2    Flamez, D.3    Schuit, F.4    Bouwens, L.5
  • 47
  • 48
    • 0036968693 scopus 로고    scopus 로고
    • Pharmacological treatment of chronic diabetes by stimulating pancreatic β-cell regeneration with systemic co-administration of EGF and gastrin
    • DOI 10.1034/j.1600-0773.2002.910621.x
    • Brand SJ, Tagerud S, Lambert P, Magil SG, Tatarkiewicz K, Doiron K, Yan Y 2002 Pharmacological treatment of chronic diabetes by stimulating pancreatic β-cell regeneration with systemic co-administration of EGF and gastrin. Pharmacol Toxicol 91:414-420 (Pubitemid 36132447)
    • (2002) Pharmacology and Toxicology , vol.91 , Issue.6 , pp. 414-420
    • Brand, S.J.1    Tagerud, S.2    Lambert, P.3    Magil, S.G.4    Tatarkiewicz, K.5    Doiron, K.6    Yan, Y.7
  • 50
    • 0027043237 scopus 로고
    • Novel expression of gastrin (cholecystokinin-B) receptors in azaserine- Induced rat pancreatic carcinoma: Receptor determination and characterization
    • Zhou W, Povoski SP, Longnecker DS, Bell Jr RH 1992 Novel expression of gastrin (cholecystokinin-B) receptors in azaserine-induced rat pancreatic carcinoma: receptor determination and characterization. Cancer Res 52:6905-6911 (Pubitemid 23006297)
    • (1992) Cancer Research , vol.52 , Issue.24 , pp. 6905-6911
    • Zhou, W.1    Povoski, S.P.2    Longnecker, D.S.3    Bell Jr., R.H.4
  • 51
    • 0028065003 scopus 로고
    • Stimulation of in vivo pancreatic growth in the rat is mediated specifically by way of cholecystokinin-A receptors
    • Povoski SP, Zhou W, Longnecker DS, Jensen RT, Mantey SA, Bell Jr RH 1994 Stimulation of in vivo pancreatic growth in the rat is mediated specifically by way of cholecystokinin-A receptors. Gastroenterology 107:1135-1146 (Pubitemid 24294577)
    • (1994) Gastroenterology , vol.107 , Issue.4 , pp. 1135-1146
    • Povoski, S.P.1    Zhou, W.2    Longnecker, D.S.3    Jensen, R.T.4    Mantey, S.A.5    Bell Jr., R.H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.