Neurotoxic factors released by stimulated human monocytes and THP-1 cells

Brain Research

Volumn 1400, Issue , 2011, Pages 99-111

  Lee, Moonhee ^a   Suk, Kyoungho ^c   Kang, Yunhee ^b   McGeer, Edith ^a   McGeer, Patrick L ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c Kyungpook National University School of Medicine   (South Korea)

Author keywords

Cyclooxygenase; Cytokine; Cytotoxicity; Glutamate; NADPH oxidase; Nitric oxide

Indexed keywords

ACETYLSALICYLIC ACID; DIPHENYLIODONIUM SALT; FREE RADICAL; GAMMA INTERFERON; GLUTAMATE DECARBOXYLASE; GLUTAMIC ACID; IBUPROFEN; INTERLEUKIN 1BETA; INTERLEUKIN 6; LACTATE DEHYDROGENASE; NITRIC OXIDE; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; PROSTAGLANDIN SYNTHASE INHIBITOR; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL CULTURE; CYTOKINE RELEASE; CYTOTOXICITY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MACROPHAGE; MONOCYTE; NEUROTOXICITY; PRIORITY JOURNAL; WESTERN BLOTTING;

ANALYSIS OF VARIANCE; ANTIBODIES; CELL LINE, TRANSFORMED; CELL LINE, TUMOR; CYCLIC N-OXIDES; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYTOKINES; DINOPROSTONE; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTAMATE DECARBOXYLASE; GLUTAMIC ACID; HUMANS; IMIDAZOLES; INTERFERON-GAMMA; L-LACTATE DEHYDROGENASE; LEUKEMIA, MONOCYTIC, ACUTE; LIPOPOLYSACCHARIDES; MOLECULAR WEIGHT; MONOCYTES; NADPH OXIDASE; NEUROTOXINS; NITRIC OXIDE SYNTHASE TYPE I; NITRITES; PYRROLES; RNA, MESSENGER; TERATOCARCINOMA;

EID: 79959373065     PISSN: 00068993     EISSN: 00068993     Source Type: Journal    
DOI: 10.1016/j.brainres.2011.05.021     Document Type: Article

References (54)

1. H. Akiyama, S. Barger, S. Barnum, B. Bradt, J. Bauer, G.M. Cole, N.R. Cooper, P. Eikelenboom, M. Emmerling, B.L. Fiebich, C.E. Finch, S. Frautschy, W.S. Griffin, H. Hampel, M. Hull, G. Landreth, L. Lue, R. Mrak, I.R. Mackenzie, P.L. McGeer, M.K. O'Banion, J. Pachter, G. Pasinetti, C. Plata-Salaman, J. Rogers, R. Rydel, Y. Shen, W. Streit, R. Strohmeyer, I. Tooyoma, F.L. Van Muiswinkel, R. Veerhuis, D. Walker, S. Webster, B. Wegrzyniak, G. Wenk, and T. Wyss-Coray Inflammation and Alzheimer's disease Neurobiol. Aging 21 3 2000 383 421 (Pubitemid 30349107)
2. P.W. Andrews, I. Damjanov, D. Simon, G.S. Banting, C. Carlin, N.C. Dracopoli, and J. Fogh Pluripotent embryonal carcinoma clones derived from the human teratocarcinoma cell line Tera-2. Differentiation in vivo and in vitro Lab. Invest. 50 2 1984 147 162 (Pubitemid 14199076)
3. R.B. Banati, J. Gehrmann, P. Schubert, and G.W. Kreutzberg Cytotoxicity of microglia Glia 7 1 1993 111 118
4. C. Bate, S. Kempster, and A. Williams Prostaglandin D2 mediates neuronal damage by amyloid-beta or prions which activates microglial cells Neuropharmacology 50 2 2006 229 237 (Pubitemid 43100008)
5. H.-O. Beutler, and G. Michal l-glutamate determination with glutamate dehydrogenase, diaphorase, and tetrazolium salts H.U. Bergmeyer, K. Gawehn, Meth. Enzym. Anal. 4 1974 Academic Press New York, NY 1708 1713
6. M.A. Brach, N.A. Cicco, D. Riedel, T. Hirano, T. Kishimoto, R.H. Mertelsmann, and F. Herrmann Mechanisms of differential regulation of interleukin-6 mRNA accumulation by tumor necrosis factor alpha and lymphotoxin during monocytic differentiation FEBS Lett. 263 2 1990 349 354 Apr 24 (Pubitemid 20143025)
7. V. Calabrese, D. Boyd-Kimball, G. Scapagnini, and D.A. Butterfield Nitric oxide and cellular stress response in brain aging and neurodegenerative disorders: the role of vitagenes Vivo 18 3 2004 245 267
8. B.J. Cao, and M.E. Reith Nitric oxide scavenger carboxy-PTIO potentiates the inhibition of dopamine uptake by nitric oxide donors Eur. J. Pharmacol. 448 1 2002 27 30 (Pubitemid 34786718)
9. C.A. Colton Heterogeneity of microglial activation in the innate immune response in the brain J. Neuroimmune Pharmacol. 4 4 2009 399 418
10. C.A. Colton, and D.L. Gilbert Production of superoxide anions by a CNS macrophage, the microglia FEBS Lett. 223 2 1987 284 288
11. F. Fang, L.F. Lue, S. Yan, H. Xu, J.S. Luddy, D. Chen, D.G. Walker, D.M. Stern, S. Yan, A.M. Schmidt, J.X. Chen, and S.S. Yan RAGE-dependent signaling in microglia contributes to neuroinflammation, Abeta accumulation, and impaired learning/memory in a mouse model of Alzheimer's disease FASEB J. 24 4 2010 1043 1055
12. M.P. Flavin, G. Zhao, and L.T. Ho Microglial tissue plasminogen activator (tPA) triggers neuronal apoptosis in vitro Glia 29 4 2000 347 354 (Pubitemid 30121424)
13. L. Gan, S. Ye, A. Chu, K. Anton, S. Yi, V.A. Vincent, D. von Schack, D. Chin, J. Murray, S. Lohr, L. Patthy, M. Gonzalez-Zulueta, K. Nikolich, and R. Urfer Identification of cathepsin B as a mediator of neuronal death induced by Abeta-activated microglial cells using a functional genomics approach J. Biol. Chem. 279 7 2004 5565 5572 (Pubitemid 38220582)
14. P.J. Gebicke-Haerter Microglia in neurodegeneration: molecular aspects Microsc. Res. Tech. 54 1 2001 47 58 (Pubitemid 32537334)
15. F. Geissmann, M.G. Manz, S. Jung, M.H. Sieweke, M. Merad, and K. Ley Development of monocytes, macrophages, and dendritic cells Science 327 5966 2010 656 661
16. D. Giulian, L.J. Haverkamp, J. Li, W.L. Karshin, J. Yu, D. Tom, X. Li, and J.B. Kirkpatrick Senile plaques stimulate microglia to release a neurotoxin found in Alzheimer brain Neurochem. Int. 27 1 1995 119 137
17. K.K. Griendling, C.A. Minieri, J.D. Ollerenshaw, and R.W. Alexander Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells Circ. Res. 74 6 1994 1141 1148 (Pubitemid 24176909)
18. B. Halliwell, and J.M. Gutteridge Biologically relevant metal ion-dependent hydroxyl radical generation. An update FEBS Lett. 307 1 1992 108 112
19. S.A. Jones, J.D. Wood, M.J. Coffey, and O.T. Jones The functional expression of p47-phox and p67-phox may contribute to the generation of superoxide by an NADPH oxidase-like system in human fibroblasts FEBS Lett. 355 2 1994 178 182
20. J.M. Kahlenberg, and G.R. Dubyak Differing caspase-1 activation states in monocyte versus macrophage models of IL-1beta processing and release J. Leukoc. Biol. 76 3 2004 676 684 (Pubitemid 39129101)
21. M. Katsuyama NOX/NADPH oxidase, the superoxide-generating enzyme: its transcriptional regulation and physiological roles J. Pharmacol. Sci. 114 2 2010 134 146
22. Y.S. Kim, S.S. Kim, J.J. Cho, D.H. Choi, O. Hwang, D.H. Shin, H.S. Chun, M.F. Beal, and T.H. Joh Matrix metalloproteinase-3: a novel signaling proteinase from apoptotic neuronal cells that activates microglia J. Neurosci. 25 14 2005 3701 3711
23. P.J. Kingham, and J.M. Pocock Microglial secreted cathepsin B induces neuronal apoptosis J. Neurochem. 76 5 2001 1475 1484 (Pubitemid 32198252)
24. A. Klegeris, and P.L. McGeer Beta-amyloid protein enhances macrophage production of oxygen free radicals and glutamate J. Neurosci. Res. 49 2 1997 229 235 (Pubitemid 27332721)
25. A. Klegeris, and P.L. McGeer Cyclooxygenase and 5-lipoxygenase inhibitors protect against mononuclear phagocyte neurotoxicity Neurobiol. Aging 23 5 2002 787 794 (Pubitemid 35217703)
26. A. Klegeris, and P.L. McGeer Non-steroidal anti-inflammatory drugs (NSAIDs) and other anti-inflammatory agents in the treatment of neurodegenerative disease Curr. Alzheimer Res. 2 3 2005 355 365 (Pubitemid 40980194)
27. A. Klegeris, and P.L. McGeer Chymotrypsin-like proteases contribute to human monocytic THP-1 cell as well as human microglial neurotoxicity Glia 51 1 2005 56 64 (Pubitemid 41059158)
28. A. Klegeris, D.G. Walker, and P.L. McGeer Regulation of glutamate in cultures of human monocytic THP-1 astyrocytoma U373 MG cells J. Neuroimmol. 78 1997 152 161 (Pubitemid 27394437)
29. A. Klegeris, D.G. Walker, and P.L. McGeer Toxicity of human THP-1 monocytic cells towards neuron-like cells is reduced by non-steroidal anti-inflammatory drugs (NSAIDs) Neuropharmacology 38 7 1999 1017 1025 (Pubitemid 29240618)
30. A. Klegeris, E.G. McGeer, and P.L. McGeer Therapeutic approaches to inflammation in neurodegenerative disease Curr. Opin. Neurol. 20 3 2007 351 357 (Pubitemid 46743120)
31. A. Klegeris, J. Li, T.K. Bammler, J. Jin, D. Zhu, D.T. Kashima, S. Pan, S. Hashioka, J. Maguire, P.L. McGeer, and J. Zhang Prolyl endopeptidase is revealed following SILAC analysis to be a novel mediator of human microglial and THP-1 cell neurotoxicity Glia 56 6 2008 675 685
32. A. Langlois, and D. Duval Differentiation of the human NT2 cells into neurons and glia Meth. Cell Sci. 19 1997 213 219 (Pubitemid 28142462)
33. M. Lee, C. Schwab, S. Yu, E. McGeer, and P.L. McGeer Astrocytes produce the antiinflammatory and neuroprotective agent hydrogen sulfide Neurobiol. Aging 30 10 2009 1523 1534
34. M. Lee, A. Sparatore, P. Del Soldato, E. McGeer, and P.L. McGeer Hydrogen sulfide-releasing NSAIDs attenuate neuroinflammation induced by microglial and astrocytic activation Glia 58 1 2010 103 113
35. I.D. Manger, and D.A. Relman How the host 'sees' pathogens: global gene expression responses to infection Curr. Opin. Immunol. 12 2 2000 215 218 (Pubitemid 30133114)
36. P.L. McGeer, and E.G. McGeer The inflammatory response system of brain: implications for therapy of alzheimer and other neurodegenerative diseases Brain Res. Rev. 21 1995 195 218 (Pubitemid 26061873)
37. E.G. McGeer, and P.L. McGeer The role of the immune system in neurodegenerative disorders Mov. Disord. 12 6 1997 855 858 (Pubitemid 27496759)
38. P.L. McGeer, and E.G. McGeer Glial reactions in Parkinson's disease Mov. Disord. 23 4 2008 474 483
39. E.G. McGeer, and P.L. McGeer Neuroinflammation in Alzheimer's disease and mild cognitive impairment: a field in its infancy J. Alzheimers Dis. 19 1 2010 355 361
40. D.M. Meisler, T. Koeck, J.T. Connor, K.S. Aulak, B.H. Jeng, J.G. Hollyfield, D.J. Stuehr, and K.G. Shadrach Inhibition of nitric oxide synthesis in corneas in storage media Exp. Eye Res. 78 4 2004 891 894 (Pubitemid 38252964)
41. L. Minghetti Cyclooxygenase-2 (COX-2) in inflammatory and degenerative brain diseases J. Neuropathol. Exp. Neurol. 63 9 2004 901 910 (Pubitemid 39202493)
42. R.A. Mufson Preparation of quiescent human monocytes for studies of colony-stimulating factor responsiveness J. Tiss. Cult. Meth. 14 1992 37 38
43. R.K. Nuttall, C. Silva, W. Hader, A. Bar-Or, K.D. Patel, D.R. Edwards, and V.W. Yong Metalloproteinases are enriched in microglia compared with leukocytes and they regulate cytokine levels in activated microglia Glia 55 5 2007 516 526 (Pubitemid 46383181)
44. I.M. Paino, J.C. Miranda, C.M. Marzocchi-Machado, E.J. Cesarino, F.A. de Castro, and A.M. de Souza Phagocytosis, oxidative burst, and produced reactive species are affected by iron deficiency anemia and anemia of chronic diseases in elderly Biol. Trace Elem. Res. 129 1-3 2009 116 125
45. F. Paquet-Durand, S. Tan, and G. Bicker Turning teratocarcinoma cells into neurons: rapid differentiation of NT-2 cells in floating spheres Brain Res. Dev. Brain Res. 142 2 2003 161 167 (Pubitemid 36593159)
46. - in the macrophage-induced glutamate-dependent cytotoxicity to neurons J. Immunol. 152 1994 3578 3585
47. G.A. Rosenberg Matrix metalloproteinases and their multiple roles in neurodegenerative diseases Lancet Neurol. 8 2 2009 205 216
48. J. Sancéau, R. Falcoff, F. Beranger, D.B. Carter, and J. Wietzerbin Secretion of interleukin-6 (IL-6) by human monocytes stimulated by muramyl dipeptide and tumour necrosis factor alpha Immunology 69 1 1990 52 56 (Pubitemid 20032153)
49. S. Tsuchiya, M. Yamabe, Y. Yamaguchi, Y. Kobayashi, T. Konno, and K. Tada Establishment and characterization of a human acute monocytic leukemia cell line (THP-1) Int. J. Cancer 26 2 1980 171 176 (Pubitemid 10086416)
50. P.S. Whitton Inflammation as a causative factor in the aetiology of Parkinson's disease Br. J. Pharmacol. 150 8 2007 963 976 (Pubitemid 46628616)
51. H.C. Williams, and K.K. Griendling NADPH oxidase inhibitors: new antihypertensive agents? J. Cardiovasc. Pharmacol. 50 1 2007 9 16 (Pubitemid 47220441)
52. K.J. Woollard, and F. Geissmann Monocytes in atherosclerosis: subsets and functions Nat. Rev. Cardiol. 7 2 2010 77 86
53. Z.M. Xin, L.M. Cao, Q.Z. Xie, Y. Sun, Y.C. Su, and Y.H. Guo Effects of the copper intrauterine device on the expression of cyclooxygenase-1 and -2 in the endometrium Int. J. Gynaecol. Obstet. 105 2 2009 166 168
54. S. Yona, and S. Jung Monocytes: subsets, origins, fates and functions Curr. Opin. Hematol. 17 1 2010 53 59