No difference in stem cell somatic mutation between the background mucosa of right- and left-sided sporadic colorectal carcinomas

Journal of Pathology

Volumn 186, Issue 1, 1998, Pages 31-35

  Campbell, Fiona ^a   Appleton, Mark A C ^a   Shields, Clive J ^a   Williams, Geraint T ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Colorectal cancer; O acetylation; Sialic acid; Somatic mutation; Tumour site

Indexed keywords

ADULT; AGED; ARTICLE; ASCENDING COLON; CANCER GRADING; CLINICAL ARTICLE; COLON MUCOSA; COLON RESECTION; COLORECTAL CARCINOMA; FEMALE; GENE MUTATION; HISTOPATHOLOGY; HUMAN; MALE; PRIORITY JOURNAL; STEM CELL;

ACETYLTRANSFERASES; AGED; AGED, 80 AND OVER; COLONIC NEOPLASMS; FEMALE; HUMANS; INTESTINAL MUCOSA; MALE; MIDDLE AGED; MUTATION; PROSPECTIVE STUDIES; RECTAL NEOPLASMS; SIGMOID NEOPLASMS; TUMOR STEM CELLS;

EID: 0031702639     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9896(199809)186:1<31::AID-PATH146>3.0.CO;2-F     Document Type: Article

References (28)

1. Morson BC, Dawson IMP, Day DW, Jass JR, Price AB, Williams GT. Morson and Dawson's Gastrointestinal Pathology. 3rd edn. Oxford: Blackwell Scientific Publications, 1990.
2. Beart RW, Melton LJ, Maruta M, et al. Trends in right and left-sided colon cancer. Dis. Colon Rectum 1983; 26: 393-398.
3. Kee F, Wilson RH, Gilliland R, et al. Changing site distribution of colorectal cancer. Br Med J 1992; 305: 158.
4. Delattre O, Law DJ, Remvikos Y, et al. Multiple genetic alterations in distal and proximal colorectal cancer. Lancet 1989; ii: 353-356.
5. Thibodeau SN, Bren G, Schaid D. Microsatellite instability in cancer of the proximal colon. Science 1993; 260: 816-819.
6. Kim HG, Jen J, Vogelstein B, Hamilton SR. Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences. Am J Pathol 1994; 145: 148-156.
7. Lanza G Jr, Maestri I, Ballotta RB, Dubini A, Cavazzini L. Relationship of nuclear DNA content to clinicopathologic features in colorectal cancer. Mod Pathol 1994; 7: 161-165.
8. Watatani M, Yoshida T, Kuroda K, Ieda S, Yasutomi M. Allelic loss of chromosome 17p, mutation of the p53 gene, and microsatellite instability in right- and left-sided colorectal cancer. Cancer 1996; 77: 1688-1693.
9. Kern SE, Fearon ER, Tersmette KWF, et al. Allelic loss in colorectal carcinoma. J Am Med Assoc 1989; 261: 3099-3103.
10. Sunter JP, Appleton DR, de Rodriguez MSB, Wright NA, Watson AJ. A comparison of cell proliferation at different sites within the large bowel of the mouse. J Anat 1979; 129: 833-842.
11. Potten CS, Kellett M, Roberts SA, et al. Measurement of in vivo proliferation in human colorectal mucosa using bromodeoxyuridine. Gut 1992; 33: 71-78.
12. Green SE, Burt AD, Appleton DR, Varma JS. Variations in cell kinetics at different sites in the human large bowel. J Pathol 1995; 175 (Suppl): 102A.
13. Park HS, Hodgson HJF, Wright NA. Crypt fission, cell proliferation and crypt population size in the normal human colon. Cell Prolif 1995; 28: 200.
14. Autrup H, Harris CC, Stoner GD, Jesudason ML, Trump BF. Binding of chemical carcinogens to macromolecules in cultures of human colon. J Natl Cancer Inst 1977; 59: 351-354.
15. Peters WHM, Kremers PG. Cytochromes P-450 in the intestinal mucosa of man. Biochem Pharmacol 1989; 38: 1535-1538.
16. Tobi M Darmon E, Rozen P, et al. Large-bowel mucosal transformation activity in persons at high risk for colorectal cancer. Scand J Gastroenterol 1995; 28: 958-962.
17. Griffiths DFR, Davies SJ, Williams D, Williams GT, Williams ED. Demonstration of somatic mutation and colonic crypt colonality by X-linked enzyme histochemistry. Nature 1988; 333: 461-163.
18. Williams ED, Lowes AP, Williams D, Williams GT. A stem cell niche theory of intestinal crypt maintenance based on a study of somatic mutation in colonic mucosa. Am J Pathol 1992, 141: 773-776.
19. Novelli MR, Williamson JA, Tomlinson IPM, et al. Polyclonal origin of colonic adenomas in an XO/XY patient with FAP. Science 1996; 272: 1187-1190.
20. Potten CS, Clonogenic, stem and carcinogen-target cells in small intestine. Scand J Gastroenterol 1984; 19 (Suppl 104): 3-14.
21. Campbell F, Appleton MAC, Fuller CE, et al. Racial variation in the O-acetylation phenotype of human colonic mucosa. J Pathol 1994; 174: 169-174.
22. Campbell F, Fuller CE, Williams GT, Williams ED. Human colonic stem cell mutation frequency with and without irradiation. J Pathol 1994; 174: 175-182.
23. Campbell F. A histochemical marker of in vivo somatic mutation within the human colon. MD thesis, University of Liverpool, 1995.
24. Fuller CE, Davies RP, Williams GT, Williams ED. Crypt restricted heterogeneity of goblet cell mucus glycoprotein in histologically normal colonic mucosa: a potential marker of somatic mutation. Br J Cancer 1990; 61: 382-384.
25. Campbell F, Williams GT, Appleton MAC, Dixon MF, Harris M, Williams ED. Post-irradiation somatic mutation and clonal stabilisation time in the human colon. Gut 1996; 39: 569-573.
26. Williams GT, Geraghty JM, Campbell F, Appleton MAC, Williams ED. Normal colonic mucosa in hereditary non-polyposis colorectal cancer shows no generalised increase in somatic mutation. Br J Cancer 1995; 71: 1077-1080.
27. Veh RW, Meessen D, Kuntz HD, May B. A new method for histo-chemical demonstration of side chain substituted sialic acids. In: Malt RA. Williamson RCN. eds. Colonic Carcinogenesis, Lancaster: MTP. 1982; 355-365.
28. Park HS, Goodlad RA, Wright NA. Crypt fission in the small intestine and colon. A mechanism for the emergence of G6PD locus-mutated crypts after treatment with mutagens. Am J Pathol 1995; 147: 1416-1427.