Rescue of aberrant gating by a genetically encoded PAS (Per-Arnt-Sim) domain in several long QT syndrome mutant human ether-á-go-go-related gene potassium channels

Journal of Biological Chemistry

Volumn 286, Issue 25, 2011, Pages 22160-22169

  Gianulis, Elena C ^a   Trudeau, Matthew C ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE BIOTINYLATION; CHANNEL GATING; DEACTIVATION KINETICS; FUNCTIONAL CHANNELS; FUNCTIONAL DEFECTS; HEK293 CELLS; IN-CHANNELS; LONG QT SYNDROME; MAMMALIAN CELLS; MUTANT HUMAN; N-TERMINALS; POTASSIUM CHANNELS; RAMP VOLTAGE; WHOLE CELL PATCH CLAMP;

CELL MEMBRANES; ELECTROPHYSIOLOGY; ETHERS; KINETICS; MAMMALS; ORGANIC COMPOUNDS; POTASSIUM;

GENES;

POTASSIUM CHANNEL HERG;

ARTICLE; BIOTINYLATION; CELL MEMBRANE; CHANNEL GATING; CONTROLLED STUDY; ENZYME INACTIVATION; HUMAN; HUMAN CELL; LONG QT SYNDROME; MUTATION; PAS DOMAIN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STRUCTURE;

ANIMALS; ELECTRIC CONDUCTIVITY; ETHER-A-GO-GO POTASSIUM CHANNELS; HEK293 CELLS; HUMANS; ION CHANNEL GATING; LONG QT SYNDROME; MODELS, MOLECULAR; MUTATION; PROTEIN STRUCTURE, TERTIARY;

MAMMALIA;

EID: 79959344863     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.205948     Document Type: Article

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