Seasonal distribution of anti-malarial drug resistance alleles on the island of Sumba, Indonesia

Malaria Journal

Volumn 8, Issue 1, 2009, Pages

  Asih, Puji Bs ^a   Rogers, William O ^b   Susanti, Agustina I ^b   Rahmat, Agus ^b   Rozi, Ismail E ^a   Kusumaningtyas, Mariska A ^a   Krisin, ^b   Sekartuti, ^c   Dewi, Rita M ^c   Coutrier, Farah N ^a   Sutamihardja, Awalludin ^b   Ven, Andre ^d   Sauerwein, Robert W ^d   Syafruddin, Din ^a,e  

^a EIJKMAN INSTITUTE FOR MOLECULAR BIOLOGY   (Indonesia)

^b US Naval Medical Research Unit No 2 Jakarta   (Indonesia)

^c NATIONAL INSTITUTE OF HEALTH RESEARCH AND DEVELOPMENT   (Indonesia)

^d RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^e HASANUDDIN UNIVERSITY   (Indonesia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL AGENT; DIHYDROFOLATE REDUCTASE; DIHYDROPTEROATE SYNTHASE; CHLOROQUINE; PROTOZOAL DNA; PROTOZOAL PROTEIN; PYRIMETHAMINE; PYRIMETHAMINE PLUS SULFADOXINE; SULFADOXINE; SULFADOXINE-PYRIMETHAMINE;

ALLELE; ARTICLE; GENE; GENE AMPLIFICATION; GENE DOSAGE; GENE MUTATION; GENETIC POLYMORPHISM; HAPLOTYPE; INDONESIA; MALARIA; NONHUMAN; PLASMODIUM FALCIPARUM; PLASMODIUM FALCIPARUM CHLOROQUINE RESISTANCE GENE; PLASMODIUM FALCIPARUM MULTIDRUG RESISTANCE 1 GENE; PROTOZOAL GENETICS; SEASONAL VARIATION; ANIMAL; DRUG COMBINATION; DRUG EFFECT; DRUG RESISTANCE; GENE FREQUENCY; GENETICS; HUMAN; METHODOLOGY; POLYMERASE CHAIN REACTION; SEASON;

ANIMALS; ANTIMALARIALS; CHLOROQUINE; DNA, PROTOZOAN; DRUG COMBINATIONS; DRUG RESISTANCE; GENE FREQUENCY; HUMANS; INDONESIA; PLASMODIUM FALCIPARUM; POLYMERASE CHAIN REACTION; PROTOZOAN PROTEINS; PYRIMETHAMINE; SEASONS; SULFADOXINE;

EID: 79959341093     PISSN: None     EISSN: 14752875     Source Type: Journal    
DOI: 10.1186/1475-2875-8-222     Document Type: Article

References (25)

1. Assessment and monitoring of antimalarial drug efficacy for the treatment of uncomplicated falciparum malaria. WHO, (WHO/HTM/RBM/200350) World Health Organization, Geneva 2003
2. A molecular marker fore chloroquine-resistant falciparum malaria. Djimde A, Doumbo OK, Cortese JF, Kayentao K, Diourte Y, Doumbo S, Dicko A, Su XZ, Nomura T, Fidock DA, Wellems TE, Plowe CV, Coulibaly D, N Engl J Med 2001 344 257 263 10.1056/NEJM200101253440403 11172152 (Pubitemid 32108530)
3. Plasmodium falciparum: detection of polymorphisms in the dihydrofolate reductase and dihydropteroate synthetase genes by PCR and restriction digestion. Duraisingh MT, Curtis J, Warhurst DC, Exp Parasitol 1998 89 1 8 10.1006/expr.1998.4274 9603482 (Pubitemid 28377366)
4. Mefloquine resistance in Plasmodium falciparum and increased pfmdr 1 gene copy number. Price RN, Uhlemann AC, Brockman A, McGready R, Ashley E, Phaipun L, Patel R, Laing K, Looareesuwan S, White NJ, Nosten F, Krishna S, Lancet 2004 364 438 447 10.1016/S0140-6736(04)16767-6 15288742 (Pubitemid 39036891)
5. Choroquine-resistant falciparum malaria from west Irian and East Kalimantan. Ebisawa I, Fukuyama T, Ann Trop Med Parasitol 1975 69 275 282 1098587
6. [Evaluation of antimalarial drugs in Indonesia 1981-1995]. Tjitra E, Gunawan S, Laihad F, Sulaksono S, Arjono S, Richie TL, Manurung N, Buletin Penelitian Kesehatan (in Indonesian) 1997 25 27 58
7. Molecular basis of antimalarial drug resistance in Indonesia. Syafruddin D, Asih PB, Siregar JE, Tjitra E, Adv Exp Med Biol 2003 531 103 115 12916784 (Pubitemid 37034442)
8. Frequency distribution of antimalarial drug resistant alleles among the isolates of Plasmodium falciparum in Purworejo District, Central Java Province. Syafruddin D, Asih PBS, Aggarwal SL, Shankar AH, Am J Trop Med Hyg 2003 33 325 330
9. Molecular epidemiology of Plasmodium falciparum resistance to antimalarial drugs in Indonesia. Syafruddin D, Asih PBS, Casey GJ, Maguire J, Baird JK, Nagesha HS, Cowman AF, Reeder JC, Am J Trop Med Hyg 2005 73 174 181 16014854 (Pubitemid 41278902)
10. Efficacy of artemisinin- based combination therapy for treatment of persons with uncomplicated Plasmodium falciparum malaria in West Sumba District, East Nusa Tenggara Province, Indonesia, and genotypic profiles of parasites. Asih PBS, Dewi RM, Tuti S, Sadikin M, Sumarto W, Sinaga B, Ven van der AJAM, Sauerwein, Syafruddin D, Am J Trop Med Hyg 2009 80 914 918 19478248
11. Seasonal prevalence of malaria in West Sumba district, Indonesia. Syafruddin D, Krisin, Asih P, Sekartuti, Dewi RM, Coutrier FN, Rozi IS, Susanti AI, Elyazar IR, Sutamiharja A, Rahmat A, Kinzer M, Rogers WO, Malar J 2009 8 8 10.1186/1475-2875-8-8 19134197
12. PCR and strain identification in Plasmodium falciparum. Wooden J, Kyes S, Sibley CH, Parasitol Today 1993 9 303 305 10.1016/0169-4758(93)90131-X 15463789 (Pubitemid 23217730)
13. Chloroquine-Resistant malaria. Wellems TE, Plowe CV, J Infect Dis 2001 184 770 776 10.1086/322858 11517439 (Pubitemid 32826429)
14. Several alleles of the multidrug-resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum. Foote SJ, Kyle DE, Martin RK, Oduola AM, Forsyth K, Kemp DJ, Cowman AF, Nature 1990 345 255 258 10.1038/345255a0 2185424 (Pubitemid 20163056)
15. Point mutations in the dihydrofolate reductase and dihydropteroate synthase genes and in vitro susceptibility to pyrimethamine and cycloguanil of Plasmodium falciparum isolates from Papua New Guinea. Reeder JC, Rieckmann KH, Genton B, Lorry K, Wines B, Cowman AF, Am J Trop Med Hyg 1996 55 209 213 8780462 (Pubitemid 26299208)
16. Real-time quantitative PCR with SYBR Green I detection for estimating copy numbers of nine drug resistance candidate genes in Plasmodium falciparum. Ferreira ID, Rosario VE, Cravo PV, Malar J 2006 5 1 10.1186/1475-2875-5-1 16420686
17. Selection of Plasmodium falciparum pfmdr1 Alleles following therapy with artemether-lumefantrine in an area of Uganda where malaria is highly endemic. Dokomajilar C, Nsobya SL, Greenhouse B, Rosenthal PJ, Dorsey G, Antimicrob Agents Chemother 2006 50 1893 1895 10.1128/AAC.50.5.1893-1895.2006 16641472
18. Failure of artesunate-mefloquine combination therapy for uncomplicated Plasmodium falciparum malaria in southern Cambodia. Rogers WO, Sem R, Tero T, Chim P, Lim P, Muth S, Socheat D, Ariey F, Wongsrichanalai C, Malar J 2009 8 10 10.1186/1475-2875-8-10 19138388
19. High-level chloroquine resistance in Sudanese isolates of Plasmodium falciparum is associated with mutations in the chloroquine resistance transporter gene, pfcrt and the multidrug resistance gene pfmdr1. Babiker HA, Pringle SJ, Abdel-Muchsin A, Mackinnon M, Hunt P, Walliker D, J Infect Dis 2001 183 1535 1538 10.1086/320195 11319692 (Pubitemid 32417707)
20. Amodiaquine resistant Plasmodium falciparum malaria in vivo is associated with selection of pfcrt 76T and pfmdr1 86Y. Holmgren G, Gil JP, Ferreira PM, Veiga MI, Obonyo CO, Bjorkman A, Infect Genet Evol 2006 6 309 314 10.1016/j.meegid.2005.09.001 16271310 (Pubitemid 43785813)
21. Selection of pfmdr1 mutations after amodiaquine monotheraphy and amodiaquine plus artemisinin combination therapy in East Africa. Holmgren G, Hamrin J, Svard J, Martesson A, Gil JP, Bjorkman A, Infect Genet Evol 2007 5 562 569 10.1016/j.meegid.2007.03.005 (Pubitemid 47338282)
22. Amodiaquine and Artemether-Lumefantrine Select Distict Alleles of the Plasmodium falciparum mdr1 Gene in Tanzanian Children Treated for Uncomplicated Malaria. Humphreys GS, Merinopoulos, Ahmed J, Whitty CJM, Mutabingwa TK, Sutherlands CJ, Hallett RL, Antimicrob Agents Chemother 2007 51 991 997 10.1128/AAC.00875-06 17194834 (Pubitemid 46355285)
23. Short report: association between chloroquine and amodiaquine resistance and allelic variation in the Plasmodium falciparum multiple drug resistance 1 gene and the chloroquine resistance transporter gene in isolates from the upper Nile in southern Sudan. Ochong EO, Broek van den IV, Keus K, Nzila A, Am J Trop Med Hyg 2003 69 184 187 13677373
24. Characterization of segmental amplification of chromosome 5 associated with multidrug resistance in Plasmodium falciparum. Nair S, Nash D, Sudimack D, Nosten F, Anderson T, Am J Trop Med Hyg 2005 93 197
25. High Prevalence of quintuple mutant dhps/dhfr genes in Plasmodium falciparum infections seven years after introduction of sulfadoxine and pyrimethamine as first line treatment in Malawi. Bwijo B, Kaneko A, Takechi M, Zungu IL, Moriyama Y, Lum JK, Tsukahara T, Mita T, Takahashi N, Bergqvist Y, Bjorkman A, Kobayakawa T, Acta Trop 2003 85 363 373 10.1016/S0001-706X(02)00264- 4 12659974 (Pubitemid 36355874)