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Volumn 12, Issue 8, 2011, Pages 1166-1186

Multifunctional mesoporous silica nanoparticles for combined therapeutic, diagnostic and targeted action in cancer treatment

Author keywords

Drug delivery systems; Gene delivery; Mesoporous silica nanoparticles (MSNs); Multidrug resistance; Multimodal imaging; Photodynamic therapy; Targeted cancer therapy; Theragnostic agents

Indexed keywords

1 (3 DIMETHYLAMINOPROPYL) 3 ETHYLCARBODIIMIDE; CETRIMIDE; CYTOCHROME C; DRUG VEHICLE; GOLD; GREEN FLUORESCENT PROTEIN; IRON OXIDE; ITRACONAZOLE; LYSOZYME; MACROGOL; NANOPARTICLE; PAPAIN; PHOSPHATE BUFFERED SALINE; PHOTOSENSITIZING AGENT; PLATINUM; POLIDOCANOL; POLOXAMER; POLY(N ISOPROPYLACRYLAMIDE); POLYGLACTIN; QUANTUM DOT; SILICON DIOXIDE; SMALL MOLECULE TRANSPORT AGENT; SODIUM CHLORIDE; SUPERPARAMAGNETIC IRON OXIDE; TRYPSIN;

EID: 79959313919     PISSN: 13894501     EISSN: 18735592     Source Type: Journal    
DOI: 10.2174/138945011795906624     Document Type: Review
Times cited : (151)

References (168)
  • 2
    • 33947225700 scopus 로고    scopus 로고
    • The present and future of nanotechnology in human health care
    • Sahoo SK, Parveen S, Panda JJ. The present and future of nanotechnology in human health care. Nanomed Nanotech Biol Med 2007; 3: 20-31.
    • (2007) Nanomed Nanotech Biol Med , vol.3 , pp. 20-31
    • Sahoo, S.K.1    Parveen, S.2    Panda, J.J.3
  • 3
    • 25444449268 scopus 로고    scopus 로고
    • Ordered mesoporous materials for bioadsorption and biocatalysis
    • Hartmann M. Ordered mesoporous materials for bioadsorption and biocatalysis. Chem Mater 2005; 17: 4577-93.
    • (2005) Chem Mater , vol.17 , pp. 4577-4593
    • Hartmann, M.1
  • 5
    • 33644860341 scopus 로고    scopus 로고
    • Recent bio-applications of sol-gel materials
    • Avnir D, Coradin T, Lev O, Livage, J. Recent bio-applications of sol-gel materials. J Mater Chem 2006; 16: 1013-30.
    • (2006) J Mater Chem , vol.16 , pp. 1013-1030
    • Avnir, D.1    Coradin, T.2    Lev, O.3    Livage, J.4
  • 6
    • 34547587931 scopus 로고    scopus 로고
    • Mesoporous silica nanoparticle based controlled release, drug delivery, and biosensor systems
    • Trewyn BG, Giri S, Slowing II, Lin, VSY. Mesoporous silica nanoparticle based controlled release, drug delivery, and biosensor systems. Chem Commun 2007; 3236-45.
    • (2007) Chem Commun , pp. 3236-3245
    • Trewyn, B.G.1    Giri, S.2    Slowing, I.I.3    Lin, V.S.Y.4
  • 7
    • 34249779229 scopus 로고    scopus 로고
    • Mesoporous silica nanomaterialbased biotechnological and biomedical delivery systems
    • Giri S, Trewyn BG, Lin VSY. Mesoporous silica nanomaterialbased biotechnological and biomedical delivery systems. Nanomedicine 2007; 2: 99-111.
    • (2007) Nanomedicine , vol.2 , pp. 99-111
    • Giri, S.1    Trewyn, B.G.2    Lin, V.S.Y.3
  • 8
    • 34249780352 scopus 로고    scopus 로고
    • Mesoporous silica nanoparticles for drug delivery and biosensing applications
    • Slowing, II, Trewyn, BG.; Giri, S, Lin VSY. Mesoporous silica nanoparticles for drug delivery and biosensing applications. Adv Funct Mater 2007; 17: 1225-36.
    • (2007) Adv Funct Mater , vol.17 , pp. 1225-1236
    • Slowing, I.I.1    Trewyn, B.G.2    Giri, S.3    Lin, V.S.Y.4
  • 9
    • 35348983485 scopus 로고    scopus 로고
    • Synthesis and functionalization of a mesoporous silica nanoparticle based on the sol-gel process and applications in controlled release
    • Trewyn, BG, Slowing, II, Giri S, Chen HT, Lin VSY. Synthesis and functionalization of a mesoporous silica nanoparticle based on the sol-gel process and applications in controlled release. Acc Chem Res 2007; 40: 846-53.
    • (2007) Acc Chem Res , vol.40 , pp. 846-853
    • Trewyn, B.G.1    Slowing, I.I.2    Giri, S.3    Chen, H.T.4    Lin, V.S.Y.5
  • 10
    • 46749123819 scopus 로고    scopus 로고
    • Mesoporous silica nanoparticles as controlled release drug delivery and gene transfection carriers
    • Slowing II, Vivero-Escoto L, Wu CW, Lin VSY. Mesoporous silica nanoparticles as controlled release drug delivery and gene transfection carriers. Adv Drug Deliv Rev 2008; 60: 1278-88.
    • (2008) Adv Drug Deliv Rev , vol.60 , pp. 1278-1288
    • Slowing, I.I.1    Vivero-Escoto, L.2    Wu, C.W.3    Lin, V.S.Y.4
  • 11
    • 38949095285 scopus 로고    scopus 로고
    • Mesoporous silicate materials as substrates for molecular machines and drug delivery
    • Angelos S, Liong M, Choi E, Zink, JI. Mesoporous silicate materials as substrates for molecular machines and drug delivery. Chem Eng J 2008; 137: 4-13.
    • (2008) Chem Eng J , vol.137 , pp. 4-13
    • Angelos, S.1    Liong, M.2    Choi, E.3    Zink, J.I.4
  • 12
  • 13
    • 70349402267 scopus 로고    scopus 로고
    • Recent development, applications, and perspectives of mesoporous silica particles in medicine and biotechnology
    • Pasqua L, Cundari S, Ceresa C, Cavaletti G. Recent development, applications, and perspectives of mesoporous silica particles in medicine and biotechnology. Curr Med Chem 2009; 16: 3054-63.
    • (2009) Curr Med Chem , vol.16 , pp. 3054-3063
    • Pasqua, L.1    Cundari, S.2    Ceresa, C.3    Cavaletti, G.4
  • 14
    • 55749096749 scopus 로고    scopus 로고
    • Ordered mesoporous materials for drug delivery
    • Wang SB. Ordered mesoporous materials for drug delivery. Microporous Mesoporous Mater 2009; 117: 1-7.
    • (2009) Microporous Mesoporous Mater , vol.117 , pp. 1-7
    • Wang, S.B.1
  • 15
    • 77950118834 scopus 로고    scopus 로고
    • Cancer-cell targeting and cellspecific delivery by mesoporous silica nanoparticles
    • Rosenholm J, Sahlgren C, Lindén M. Cancer-cell targeting and cellspecific delivery by mesoporous silica nanoparticles. J Mater Chem 2010; 20: 2707-13.
    • (2010) J Mater Chem , vol.20 , pp. 2707-2713
    • Rosenholm, J.1    Sahlgren, C.2    Lindén, M.3
  • 16
    • 0026931265 scopus 로고
    • Ordered mesoporous molecular-sieves synthesized by a liquid-crystal template mechanism
    • Kresge CT, Leonowicz ME, Roth WJ, Vartuli JC. Ordered mesoporous molecular-sieves synthesized by a liquid-crystal template mechanism. Nature 1992; 359: 710-2.
    • (1992) Nature , vol.359 , pp. 710-712
    • Kresge, C.T.1    Leonowicz, M.E.2    Roth, W.J.3    Vartuli, J.C.4
  • 17
    • 0012247651 scopus 로고
    • A new family of mesoporous molecular-sieves prepared with liquid-crystal templates
    • Beck JS, Vartuli JC, Roth WJ, et al. A new family of mesoporous molecular-sieves prepared with liquid-crystal templates. J Am Chem Soc 1992; 114: 10834-43.
    • (1992) J Am Chem Soc , vol.114 , pp. 10834-10843
    • Beck, J.S.1    Vartuli, J.C.2    Roth, W.J.3
  • 18
    • 0025168065 scopus 로고
    • The preparation of alkyltrimethylammonium-kanemite complexes and their conversion to microporous materials
    • Yanagisawa T, Shimizu T, Kuroda K, Kato C. The preparation of alkyltrimethylammonium-kanemite complexes and their conversion to microporous materials. Bull Chem Soc Jpn 1990; 63: 988-92.
    • (1990) Bull Chem Soc Jpn , vol.63 , pp. 988-992
    • Yanagisawa, T.1    Shimizu, T.2    Kuroda, K.3    Kato, C.4
  • 19
    • 69249105277 scopus 로고    scopus 로고
    • For examples of MSN synthesis, see for instance, and references therein
    • For examples of MSN synthesis, see for instance: Urata C, Aoyama Y, Tonegawa A, Yamauchia Y, Kuroda K. Chem Commun 2009; 5094-6, and references therein.
    • (2009) Chem Commun , pp. 5094-5096
    • Urata, C.1    Aoyama, Y.2    Tonegawa, A.3    Yamauchia, Y.4    Kuroda, K.5
  • 20
    • 35148847927 scopus 로고    scopus 로고
    • Synthesis of stable colloidal suspensions of ordered mesostructured silica from sodium metasilicate using pluronic P123 and mildly acidic conditions
    • Berggren A, Holmberg K, Palmqvist AEC. Synthesis of stable colloidal suspensions of ordered mesostructured silica from sodium metasilicate using pluronic P123 and mildly acidic conditions. Stud Surf Sci Catal 2007; 165: 53-6.
    • (2007) Stud Surf Sci Catal , vol.165 , pp. 53-56
    • Berggren, A.1    Holmberg, K.2    Palmqvist, A.E.C.3
  • 22
    • 54049086916 scopus 로고    scopus 로고
    • Environmental friendly rapid mass production synthetic process of highly ordered nanometer sized mesoporous silica using a combination of acid-base and evaporation approach
    • Kapoor MP, Fujii W, Yanagi M, et al. Environmental friendly rapid mass production synthetic process of highly ordered nanometer sized mesoporous silica using a combination of acid-base and evaporation approach. Microporous Mesoporous Mater 2008; 116: 370-7.
    • (2008) Microporous Mesoporous Mater , vol.116 , pp. 370-377
    • Kapoor, M.P.1    Fujii, W.2    Yanagi, M.3
  • 23
    • 9644263927 scopus 로고    scopus 로고
    • Core-shell synthesis of a novel, spherical, mesoporous silica/platinum nanocomposite: Pt/PVP@MCM-41
    • Lin KJ, Chen LJ, Prasad MR, Cheng CY. Core-shell synthesis of a novel, spherical, mesoporous silica/platinum nanocomposite: Pt/PVP@MCM-41. Adv Mater 2004; 16: 1845-9.
    • (2004) Adv Mater , vol.16 , pp. 1845-1849
    • Lin, K.J.1    Chen, L.J.2    Prasad, M.R.3    Cheng, C.Y.4
  • 24
    • 58849122636 scopus 로고    scopus 로고
    • Thermally stable Pt/mesoporous silica core-shell nanocatalysts for high-temperature reactions
    • Joo SH, Park JY, Tsung CK, Yamada Y, Yang P, Somorjai GA. Thermally stable Pt/mesoporous silica core-shell nanocatalysts for high-temperature reactions. Nature Mater 2009; 8: 126-31.
    • (2009) Nature Mater , vol.8 , pp. 126-131
    • Joo, S.H.1    Park, J.Y.2    Tsung, C.K.3    Yamada, Y.4    Yang, P.5    Somorjai, G.A.6
  • 25
    • 0037018438 scopus 로고    scopus 로고
    • Selfassembled highly ordered spherical mesoporous silica/gold nanocomposites
    • Nooney RI, Dhanasekaran, T, Chen Y, Josephs R, Ostafin AE. Selfassembled highly ordered spherical mesoporous silica/gold nanocomposites. Adv Mater 2002; 14: 529-32.
    • (2002) Adv Mater , vol.14 , pp. 529-532
    • Nooney, R.I.1    Dhanasekaran, T.2    Chen, Y.3    Josephs, R.4    Ostafin, A.E.5
  • 27
    • 38749132806 scopus 로고    scopus 로고
    • Single-step coating of mesoporous silica on cetyltrimethyl ammonium bromide-capped nanoparticles
    • Gorelikov I, Matsuura N. Single-step coating of mesoporous silica on cetyltrimethyl ammonium bromide-capped nanoparticles. Nano Lett 2008; 8: 369-73.
    • (2008) Nano Lett , vol.8 , pp. 369-373
    • Gorelikov, I.1    Matsuura, N.2
  • 28
    • 33744926944 scopus 로고    scopus 로고
    • Ordered nanocrystal/ silica particles self-assembled from nanocrystal micelles and silicate
    • Fan H, Gabaldon J, Brinker CJ, Jiang YB. Ordered nanocrystal/ silica particles self-assembled from nanocrystal micelles and silicate. Chem Commun 2006; 2323-5.
    • (2006) Chem Commun , pp. 2323-2325
    • Fan, H.1    Gabaldon, J.2    Brinker, C.J.3    Jiang, Y.B.4
  • 29
    • 34247630558 scopus 로고    scopus 로고
    • Single gold nanoparticles encapsulated in monodispersed regular spheres of mesostructured silica produced by pseudomorphic transformation
    • Botella P, Corma A, Navarro MT. Single gold nanoparticles encapsulated in monodispersed regular spheres of mesostructured silica produced by pseudomorphic transformation. Chem Mater 2007; 19: 1979-83.
    • (2007) Chem Mater , vol.19 , pp. 1979-1983
    • Botella, P.1    Corma, A.2    Navarro, M.T.3
  • 30
    • 33646042910 scopus 로고    scopus 로고
    • Aerosol-assisted self-assembly of singlecrystal core/nanoporous shell particles as model controlled release capsules
    • Jiang X, Brinker CJ. Aerosol-assisted self-assembly of singlecrystal core/nanoporous shell particles as model controlled release capsules. J Am Chem Soc 2006; 128: 4512-3.
    • (2006) J Am Chem Soc , vol.128 , pp. 4512-4513
    • Jiang, X.1    Brinker, C.J.2
  • 31
    • 31444433942 scopus 로고    scopus 로고
    • Magnetic fluorescent delivery vehicle using uniform mesoporous silica spheres embedded with monodisperse magnetic and semiconductor nanocrystals
    • Kim J, Lee JE, Lee J, et al. Magnetic fluorescent delivery vehicle using uniform mesoporous silica spheres embedded with monodisperse magnetic and semiconductor nanocrystals. J Am Chem Soc 2006; 128: 688-9.
    • (2006) J Am Chem Soc , vol.128 , pp. 688-689
    • Kim, J.1    Lee, J.E.2    Lee, J.3
  • 32
    • 66149092675 scopus 로고    scopus 로고
    • Antimicrobial activity of silver nanocrystals encapsulated in mesoporous silica nanoparticles
    • Liong M, France B, Bradley KA, Zink JI. Antimicrobial Activity of Silver Nanocrystals Encapsulated in Mesoporous Silica Nanoparticles. Adv Mater 2009; 21: 1684-9.
    • (2009) Adv Mater , vol.21 , pp. 1684-1689
    • Liong, M.1    France, B.2    Bradley, K.A.3    Zink, J.I.4
  • 34
    • 54249135767 scopus 로고    scopus 로고
    • Multifunctional uniform nanoparticles composed of a magnetite nanocrystal core and a mesoporous silica shell for magnetic resonance and fluorescence imaging and for drug delivery
    • Kim J, Kim HS, Lee N, et al. Multifunctional uniform nanoparticles composed of a magnetite nanocrystal core and a mesoporous silica shell for magnetic resonance and fluorescence imaging and for drug delivery. Angew Chem Int Ed 2008; 47: 8438-41.
    • (2008) Angew Chem Int Ed , vol.47 , pp. 8438-8441
    • Kim, J.1    Kim, H.S.2    Lee, N.3
  • 35
    • 69849110521 scopus 로고    scopus 로고
    • Synthesis and characterization of biocompatible and size-tunable multifunctional porous silica nanoparticles
    • Lin YS, Haynes CL. Synthesis and characterization of biocompatible and size-tunable multifunctional porous silica nanoparticles. Chem Mater 2009; 21: 3979-86.
    • (2009) Chem Mater , vol.21 , pp. 3979-3986
    • Lin, Y.S.1    Haynes, C.L.2
  • 36
    • 2342628580 scopus 로고    scopus 로고
    • Template-assisted synthesis of mesoporous magnetic nanocomposite particles
    • Wu P, Zhu J, Xu Z. Template-assisted synthesis of mesoporous magnetic nanocomposite particles. Adv Funct Mater 2004; 14: 345-51.
    • (2004) Adv Funct Mater , vol.14 , pp. 345-351
    • Wu, P.1    Zhu, J.2    Xu, Z.3
  • 37
    • 21244467798 scopus 로고    scopus 로고
    • Fabrication of uniform magnetic nanocomposite spheres with a magnetic core/mesoporous silica shell structure
    • Zhao W, Gu J, Zhang L, Chen H, Shi J. Fabrication of uniform magnetic nanocomposite spheres with a magnetic core/mesoporous silica shell structure. J Am Chem Soc 2005; 127: 8916-7.
    • (2005) J Am Chem Soc , vol.127 , pp. 8916-8917
    • Zhao, W.1    Gu, J.2    Zhang, L.3    Chen, H.4    Shi, J.5
  • 39
    • 33846271420 scopus 로고    scopus 로고
    • Particle size, uniformity, and mesostructure control of magnetic core/mesoporous silica shell nanocomposite spheres
    • Zhao W, Shi J, Chen H, Zhang L. Particle size, uniformity, and mesostructure control of magnetic core/mesoporous silica shell nanocomposite spheres. J Mater Res 2006; 21: 3080-9.
    • (2006) J Mater Res , vol.21 , pp. 3080-3089
    • Zhao, W.1    Shi, J.2    Chen, H.3    Zhang, L.4
  • 40
    • 20444406055 scopus 로고
    • Controlled growth of monodisperse silica spheres in micron size range
    • Stöber W, Fink A, Bohn E. Controlled growth of monodisperse silica spheres in micron size range. J Colloid Interface Sci 1968; 26: 62-9.
    • (1968) J Colloid Interface Sci , vol.26 , pp. 62-69
    • Stöber, W.1    Fink, A.2    Bohn, E.3
  • 41
    • 0037154469 scopus 로고    scopus 로고
    • Metallodielectric colloidal core-shell particles for photonic applications
    • Graf C, van Blaaderen A. Metallodielectric colloidal core-shell particles for photonic applications. Langmuir 2002; 18: 524-32.
    • (2002) Langmuir , vol.18 , pp. 524-532
    • Graf, C.1    van Blaaderen, A.2
  • 42
    • 34250841672 scopus 로고    scopus 로고
    • Synthesis of monodisperse spherical silica particles with solid core and mesoporous shell: Mesopore channels perpendicular to the surface
    • Yoon SB, Kim JY, Kim JH, et al. Synthesis of monodisperse spherical silica particles with solid core and mesoporous shell: mesopore channels perpendicular to the surface. J Mater Chem 2007; 17: 1758-61.
    • (2007) J Mater Chem , vol.17 , pp. 1758-1761
    • Yoon, S.B.1    Kim, J.Y.2    Kim, J.H.3
  • 43
    • 37449013066 scopus 로고    scopus 로고
    • Synthesis of monodisperse silica spheres with solid core and mesoporous shell: Morphological control of mesopores
    • Kim JH, Yoon SB, Kim JY, Chae YB, Yu JS. Synthesis of monodisperse silica spheres with solid core and mesoporous shell: Morphological control of mesopores. Colloids Surf A Physicochem Eng Aspects 2008; 313-314: 77-81.
    • (2008) Colloids Surf a Physicochem Eng Aspects , vol.313-314 , pp. 77-81
    • Kim, J.H.1    Yoon, S.B.2    Kim, J.Y.3    Chae, Y.B.4    Yu, J.S.5
  • 44
    • 33847404403 scopus 로고    scopus 로고
    • Formation mechanism for monodispersed mesoporous silica spheres and its application to the synthesis of core/shell particles
    • Nakamura T, Mizutani M, Nozaki H, Suzuki N, Yano K. Formation mechanism for monodispersed mesoporous silica spheres and its application to the synthesis of core/shell particles. J Phys Chem C 2007; 111: 1093-100.
    • (2007) J Phys Chem C , vol.111 , pp. 1093-1100
    • Nakamura, T.1    Mizutani, M.2    Nozaki, H.3    Suzuki, N.4    Yano, K.5
  • 45
    • 67649387942 scopus 로고    scopus 로고
    • Functionalization of mesostructured inorganicorganic and porous inorganic materials
    • For a recent review, see for instance
    • For a recent review, see for instance: Athens GL, Shayib RM, Chmelka BF. Functionalization of mesostructured inorganicorganic and porous inorganic materials. Curr Opin Colloids Interface Sci 2009; 14: 281-92.
    • (2009) Curr Opin Colloids Interface Sci , vol.14 , pp. 281-292
    • Athens, G.L.1    Shayib, R.M.2    Chmelka, B.F.3
  • 46
    • 0344012966 scopus 로고    scopus 로고
    • A novel anionic surfactant templating route for synthesizing mesoporous silica with unique structure
    • Che S, Garcia-Bennett AE, Yokoi T, et al. A novel anionic surfactant templating route for synthesizing mesoporous silica with unique structure. Nat Mater 2003; 2: 801-5.
    • (2003) Nat Mater , vol.2 , pp. 801-805
    • Che, S.1    Garcia-Bennett, A.E.2    Yokoi, T.3
  • 47
    • 0033891996 scopus 로고    scopus 로고
    • Selective functionalization of mesoporous silica
    • de Juan F, Ruiz-Hitzky E. Selective functionalization of mesoporous silica. Adv Mater 2000; 12: 430-2.
    • (2000) Adv Mater , vol.12 , pp. 430-432
    • de Juan, F.1    Ruiz-Hitzky, E.2
  • 48
    • 39849086690 scopus 로고    scopus 로고
    • Hyperbranching surface polymerization as a tool for preferential functionalization of the outer surface of mesoporous silica
    • Rosenholm JM, Duchanoy A, Lindén M. Hyperbranching surface polymerization as a tool for preferential functionalization of the outer surface of mesoporous silica. Chem Mater 2008; 20: 1126-33.
    • (2008) Chem Mater , vol.20 , pp. 1126-1133
    • Rosenholm, J.M.1    Duchanoy, A.2    Lindén, M.3
  • 49
    • 57949115434 scopus 로고    scopus 로고
    • Selective functionalization of the outer and inner surfaces in mesoporous silica nanoparticles
    • Kecht J, Schlossbauer A, Bein T. Selective Functionalization of the Outer and Inner Surfaces in Mesoporous Silica Nanoparticles. Chem Mater 2008; 20: 7207-14.
    • (2008) Chem Mater , vol.20 , pp. 7207-7214
    • Kecht, J.1    Schlossbauer, A.2    Bein, T.3
  • 50
    • 72149112463 scopus 로고    scopus 로고
    • The effect of PEGylation of mesoporous silica nanoparticles on nonspecific binding of serum proteins and cellular responses
    • He Q, Zhang J, Shi J, et al. The effect of PEGylation of mesoporous silica nanoparticles on nonspecific binding of serum proteins and cellular responses. Biomaterials 2010; 31:1085-92.
    • (2010) Biomaterials , vol.31 , pp. 1085-1092
    • He, Q.1    Zhang, J.2    Shi, J.3
  • 51
    • 65349175964 scopus 로고    scopus 로고
    • Magnetic mesoporous silica spheres for drug targeting and controlled release
    • Huang S, Fan Y, Cheng Z, et al. Magnetic mesoporous silica spheres for drug targeting and controlled release. J Phys Chem C 2009; 113: 1775-84.
    • (2009) J Phys Chem C , vol.113 , pp. 1775-1784
    • Huang, S.1    Fan, Y.2    Cheng, Z.3
  • 52
    • 23944494146 scopus 로고    scopus 로고
    • Stimuli-responsive controlled drug release from a hollow mesoporous silica sphere/polyelectrolyte multilayer core-shell structure
    • Zhu Y, Shi J, Shen W, et al. Stimuli-responsive controlled drug release from a hollow mesoporous silica sphere/polyelectrolyte multilayer core-shell structure. Angew Chem Int Ed 2005; 44: 5083-7.
    • (2005) Angew Chem Int Ed , vol.44 , pp. 5083-5087
    • Zhu, Y.1    Shi, J.2    Shen, W.3
  • 53
    • 34249280959 scopus 로고    scopus 로고
    • A mesoporous core-shell structure for pH-controlled storage and release of water-soluble drug
    • Zhu Y, Shi J. A mesoporous core-shell structure for pH-controlled storage and release of water-soluble drug. Microporous Mesoporous Mater 2007; 103: 243-9.
    • (2007) Microporous Mesoporous Mater , vol.103 , pp. 243-249
    • Zhu, Y.1    Shi, J.2
  • 54
    • 45749101676 scopus 로고    scopus 로고
    • Temperaturecontrolled uptake and release in PNIPAM-modified porous silica nanoparticles
    • You YZ, Kalebaila KK, Brock SL, Oupický D. Temperaturecontrolled uptake and release in PNIPAM-modified porous silica nanoparticles. Chem Mater 2008; 20: 3354-9.
    • (2008) Chem Mater , vol.20 , pp. 3354-3359
    • You, Y.Z.1    Kalebaila, K.K.2    Brock, S.L.3    Oupický, D.4
  • 55
    • 36849034971 scopus 로고    scopus 로고
    • Control of drug release through the in situ assembly of stimuli-responsive ordered mesoporous silica with magnetic particles
    • Zhu S, Zhou Z, Zhang D. Control of drug release through the in situ assembly of stimuli-responsive ordered mesoporous silica with magnetic particles. ChemPhysChem 2007; 8: 2478-83.
    • (2007) ChemPhysChem , vol.8 , pp. 2478-2483
    • Zhu, S.1    Zhou, Z.2    Zhang, D.3
  • 56
    • 18644365075 scopus 로고    scopus 로고
    • Comparative studies of grafting and direct syntheses of inorganic-organic hybrid mesoporous materials
    • Lim MH, Stein A. Comparative studies of grafting and direct syntheses of inorganic-organic hybrid mesoporous materials. Chem Mater 1999; 11: 3285-95.
    • (1999) Chem Mater , vol.11 , pp. 3285-3295
    • Lim, M.H.1    Stein, A.2
  • 57
    • 0027910491 scopus 로고
    • Surface characterization of amorphous silica - a review of work from the former USSR
    • Zhuravlev LT. Surface characterization of amorphous silica - a review of work from the former USSR. Colloids Surf A Physicochem Eng Aspects 1993; 74: 71-90.
    • (1993) Colloids Surf a Physicochem Eng Aspects , vol.74 , pp. 71-90
    • Zhuravlev, L.T.1
  • 59
    • 43449127485 scopus 로고    scopus 로고
    • Towards establishing structure-activity relationships for mesoporous silica in drug delivery applications
    • Rosenholm JM, Lindén M. Towards establishing structure-activity relationships for mesoporous silica in drug delivery applications. J Control Release 2008; 128: 157-64.
    • (2008) J Control Release , vol.128 , pp. 157-164
    • Rosenholm, J.M.1    Lindén, M.2
  • 60
    • 33748109375 scopus 로고    scopus 로고
    • A study of carboxylic-modified mesoporous silica in controlled delivery for drug famotidine
    • Tang Q, Xua Y, Wua D, Sun Y. A study of carboxylic-modified mesoporous silica in controlled delivery for drug famotidine. J Solid State Chem 2006; 179: 1513-20.
    • (2006) J Solid State Chem , vol.179 , pp. 1513-1520
    • Tang, Q.1    Xua, Y.2    Wua, D.3    Sun, Y.4
  • 61
    • 25444449268 scopus 로고    scopus 로고
    • Ordered mesoporous materials for bioadsorption and biocatalysis
    • Hartmann M. Ordered mesoporous materials for bioadsorption and biocatalysis. Chem Mater 2005; 17: 4577-93.
    • (2005) Chem Mater , vol.17 , pp. 4577-4593
    • Hartmann, M.1
  • 63
    • 0030569494 scopus 로고    scopus 로고
    • Enzyme immobilization in MCM-41 molecular sieve
    • Diaz JF, Balkus KF Jr. Enzyme immobilization in MCM-41 molecular sieve. J Mol Catal B 1996; 2: 115-26.
    • (1996) J Mol Catal B , vol.2 , pp. 115-126
    • Diaz, J.F.1    Balkus Jr., K.F.2
  • 64
    • 0035820045 scopus 로고    scopus 로고
    • Adsorption and activity of cytochrome c on mesoporous silicates
    • Deere J, Magner E, Wall JG, Hodnett BK. Adsorption and activity of cytochrome c on mesoporous silicates. Chem Commun 2001; 465-6.
    • (2001) Chem Commun , pp. 465-466
    • Deere, J.1    Magner, E.2    Wall, J.G.3    Hodnett, B.K.4
  • 66
    • 3543073408 scopus 로고    scopus 로고
    • Adsorption of cytochrome c on mesoporous molecular sieves: Influence of ph, pore diameter, and aluminum incorporation
    • Vinu A, Murugesan V, Tangermann O, Hartmann M. Adsorption of cytochrome c on mesoporous molecular sieves: influence of ph, pore diameter, and aluminum incorporation. Chem Mater 2004; 16: 3056-65.
    • (2004) Chem Mater , vol.16 , pp. 3056-3065
    • Vinu, A.1    Murugesan, V.2    Tangermann, O.3    Hartmann, M.4
  • 67
    • 2942700166 scopus 로고    scopus 로고
    • Adsorption of lysozyme over mesoporous molecular sieves mcm-41 and sba-15: Influence of ph and aluminum incorporation
    • Vinu, A, Murugesan V, Tangermann O, Hartmann M. Adsorption of lysozyme over mesoporous molecular sieves mcm-41 and sba-15: influence of ph and aluminum incorporation. J Phys Chem B 2004; 108: 7323-30.
    • (2004) J Phys Chem B , vol.108 , pp. 7323-7330
    • Vinu, A.1    Murugesan, V.2    Tangermann, O.3    Hartmann, M.4
  • 68
    • 74349125200 scopus 로고    scopus 로고
    • Architecture and performance of mesoporous silica-lipase hybrids via non-covalent interfacial adsorption
    • Lu S, He J, Guo X. Architecture and performance of mesoporous silica-lipase hybrids via non-covalent interfacial adsorption. AICHE J 2010; 56: 506-14.
    • (2010) AICHE J , vol.56 , pp. 506-514
    • Lu, S.1    He, J.2    Guo, X.3
  • 69
    • 0033610438 scopus 로고    scopus 로고
    • Mesoporous silicate sequestration and release of proteins
    • Han Y-J, Stucky GD, Butler A. Mesoporous silicate sequestration and release of proteins. J Am Chem Soc 1999; 121: 9897-8.
    • (1999) J Am Chem Soc , vol.121 , pp. 9897-9898
    • Han, Y.-J.1    Stucky, G.D.2    Butler, A.3
  • 70
    • 34548434374 scopus 로고    scopus 로고
    • Mesoporous silica nanoparticles for intracellular delivery of membrane-impermeable proteins
    • Slowing II, Trewyn BG, Lin VS-Y. Mesoporous silica nanoparticles for intracellular delivery of membrane-impermeable proteins. J Am Chem Soc 2007; 129: 8845-9.
    • (2007) J Am Chem Soc , vol.129 , pp. 8845-8849
    • Slowing, I.I.1    Trewyn, B.G.2    Lin, V.S.-Y.3
  • 71
    • 33748273545 scopus 로고    scopus 로고
    • Adsorption of DNA into mesoporous silica
    • Solberg SM, Landry CC. Adsorption of DNA into mesoporous silica. J Phys Chem B 2006; 110: 15261-8.
    • (2006) J Phys Chem B , vol.110 , pp. 15261-15268
    • Solberg, S.M.1    Landry, C.C.2
  • 72
    • 70350639581 scopus 로고    scopus 로고
    • Polyethyleneimine coating enhances the cellular uptake of mesoporous silica nanoparticles and allows safe delivery of siRNA and DNA constructs
    • Xia T, Kovochich M, Liong M, et al. Polyethyleneimine coating enhances the cellular uptake of mesoporous silica nanoparticles and allows safe delivery of siRNA and DNA constructs. ACS Nano 2009; 3: 3273-86.
    • (2009) ACS Nano , vol.3 , pp. 3273-3286
    • Xia, T.1    Kovochich, M.2    Liong, M.3
  • 74
    • 6344261554 scopus 로고    scopus 로고
    • Influences of material characteristics on ibuprofen drug loading and release profiles from ordered micro- and mesoporous silica matrices
    • Andersson J, Rosenholm J, Areva S, Lindén M. Influences of material characteristics on ibuprofen drug loading and release profiles from ordered micro- and mesoporous silica matrices. Chem Mater 2004; 16: 4160-7.
    • (2004) Chem Mater , vol.16 , pp. 4160-4167
    • Andersson, J.1    Rosenholm, J.2    Areva, S.3    Lindén, M.4
  • 75
    • 0036942095 scopus 로고    scopus 로고
    • Mesoporous silicate as matrix for drug delivery systems of nonsteroidal antinflammatory drugs
    • Aiello R, Cavallaro G, Giammona G, Pasqua L, Pierro P, Testa F. Mesoporous silicate as matrix for drug delivery systems of nonsteroidal antinflammatory drugs. Stud Surf Sci Catal 2002; 142: 1165-72.
    • (2002) Stud Surf Sci Catal , vol.142 , pp. 1165-1172
    • Aiello, R.1    Cavallaro, G.2    Giammona, G.3    Pasqua, L.4    Pierro, P.5    Testa, F.6
  • 76
    • 0000144528 scopus 로고    scopus 로고
    • Adsorption of taxol into ordered mesoporous silicas with various pore diameters
    • Hata H, Saeki S, Kimura T, Sugahara Y, Kuroda K. Adsorption of taxol into ordered mesoporous silicas with various pore diameters. Chem Mater 1999; 11: 1110-9.
    • (1999) Chem Mater , vol.11 , pp. 1110-1119
    • Hata, H.1    Saeki, S.2    Kimura, T.3    Sugahara, Y.4    Kuroda, K.5
  • 77
    • 0037060084 scopus 로고    scopus 로고
    • Study of adsorption processes of model drugs at supercritical conditions using partial least squares regression
    • Domingo C, García-Carmona J, Fanovich MA, Saurina J. Study of adsorption processes of model drugs at supercritical conditions using partial least squares regression. Anal Chim Acta 2002; 452: 311-9.
    • (2002) Anal Chim Acta , vol.452 , pp. 311-319
    • Domingo, C.1    García-Carmona, J.2    Fanovich, M.A.3    Saurina, J.4
  • 78
    • 72149105048 scopus 로고    scopus 로고
    • Impregnation of vitamin E acetate on silica mesoporous phases using supercritical carbon dioxide
    • Belhadj-Ahmed F, Badens E, Llewellyn P, Denoyel R, Charbit G. Impregnation of vitamin E acetate on silica mesoporous phases using supercritical carbon dioxide. J Supercritical Fluids 2009; 51: 278-86.
    • (2009) J Supercritical Fluids , vol.51 , pp. 278-286
    • Belhadj-Ahmed, F.1    Badens, E.2    Llewellyn, P.3    Denoyel, R.4    Charbit, G.5
  • 79
    • 65949107070 scopus 로고    scopus 로고
    • Ibuprofen loading into mesostructured silica using liquid carbon dioxide as a solvent
    • Hillerström A, van Stam J, Andersson M. Ibuprofen loading into mesostructured silica using liquid carbon dioxide as a solvent. Green Chem 2009; 11: 662-7.
    • (2009) Green Chem , vol.11 , pp. 662-667
    • Hillerström, A.1    van Stam, J.2    Andersson, M.3
  • 80
    • 67650722965 scopus 로고    scopus 로고
    • Accessibility of amino groups in postsynthetically modified mesoporous silica
    • Ritter H, Brühwiler D. Accessibility of amino groups in postsynthetically modified mesoporous silica. J Phys Chem C 2009; 113: 10667-74.
    • (2009) J Phys Chem C , vol.113 , pp. 10667-10674
    • Ritter, H.1    Brühwiler, D.2
  • 81
    • 0142074279 scopus 로고    scopus 로고
    • Synthesis and characterisation of ibuprofen-anchored MCM-41 silica and silica gel
    • Tourné-Péteilh C, Brunel D, Bégu S, et al. Synthesis and characterisation of ibuprofen-anchored MCM-41 silica and silica gel. New J Chem 2003; 27: 1415-8.
    • (2003) New J Chem , vol.27 , pp. 1415-1418
    • Tourné-Péteilh, C.1    Brunel, D.2    Bégu, S.3
  • 82
    • 66449096268 scopus 로고    scopus 로고
    • Cell-induced intracellular controlled release of membrane impermeable cysteine from a mesoporous silica nanoparticle-based drug delivery system
    • Mortera R, Vivero-Escoto J, Slowing II, Garrone E, Onida B, Lin VS-Y. Cell-induced intracellular controlled release of membrane impermeable cysteine from a mesoporous silica nanoparticle-based drug delivery system. Chem Commun 2009; 3219-21.
    • (2009) Chem Commun , pp. 3219-3221
    • Mortera, R.1    Vivero-Escoto, J.2    Slowing, I.I.3    Garrone, E.4    Onida, B.5    Lin, V.S.-Y.6
  • 83
    • 77953165953 scopus 로고    scopus 로고
    • Cancer-cell-specific induction of apoptosis using mesoporous silica nanoparticles as drug-delivery vectors
    • Rosenholm JM, Peuhu E, Bate-Eya LT, Eriksson J-E, Sahlgren C, Lindén M. Cancer-cell-specific induction of apoptosis using mesoporous silica nanoparticles as drug-delivery vectors. Small 2010; 6: 1234-41.
    • (2010) Small , vol.6 , pp. 1234-1241
    • Rosenholm, J.M.1    Peuhu, E.2    Bate-Eya, L.T.3    Eriksson, J.-E.4    Sahlgren, C.5    Lindén, M.6
  • 84
    • 36248992978 scopus 로고    scopus 로고
    • Silica-based mesoporous materials as drug delivery system for methotrexate release
    • Carino IS, Pasqua L, Testa F, et al. Silica-based mesoporous materials as drug delivery system for methotrexate release. Drug Deliv 2007; 14: 491-5.
    • (2007) Drug Deliv , vol.14 , pp. 491-495
    • Carino, I.S.1    Pasqua, L.2    Testa, F.3
  • 85
    • 50849113733 scopus 로고    scopus 로고
    • Physical state of poorly water soluble therapeutic molecules loaded into sba-15 ordered mesoporous silica carriers: A case study with itraconazole and ibuprofen
    • Mellaerts R, Jammaer JAG, van Speybroeck M, et al. physical state of poorly water soluble therapeutic molecules loaded into sba-15 ordered mesoporous silica carriers: a case study with itraconazole and ibuprofen. Langmuir 2008; 24: 8651-9.
    • (2008) Langmuir , vol.24 , pp. 8651-8659
    • Mellaerts, R.1    Jammaer, J.A.G.2    van Speybroeck, M.3
  • 86
    • 70349968163 scopus 로고    scopus 로고
    • Targeted intracellular delivery of hydrophobic agents using mesoporous hybrid silica nanoparticles as carrier systems
    • Rosenholm JM, Peuhu E, Eriksson JE, Sahlgren C, Lindén M. Targeted intracellular delivery of hydrophobic agents using mesoporous hybrid silica nanoparticles as carrier systems. Nano Lett 2009; 9: 3308-11.
    • (2009) Nano Lett , vol.9 , pp. 3308-3311
    • Rosenholm, J.M.1    Peuhu, E.2    Eriksson, J.E.3    Sahlgren, C.4    Lindén, M.5
  • 87
    • 73349141177 scopus 로고    scopus 로고
    • Co-delivery of doxorubicin and Bcl-2 sirna by mesoporous silica nanoparticles enhances the efficacy of chemotherapy in multidrug-resistant cancer cells
    • Chen AM, Zhang M, Wei D, et al. Co-delivery of doxorubicin and Bcl-2 sirna by mesoporous silica nanoparticles enhances the efficacy of chemotherapy in multidrug-resistant cancer cells. Small 2009; 5: 2673-7.
    • (2009) Small , vol.5 , pp. 2673-2677
    • Chen, A.M.1    Zhang, M.2    Wei, D.3
  • 88
    • 67650521855 scopus 로고    scopus 로고
    • Mesoporous silica nanoparticle-based double drug delivery system for glucoseresponsive controlled release of insulin and cyclic AMP
    • Zhao Y, Trewyn BG, Slowing II, Lin VS-Y. Mesoporous silica nanoparticle-based double drug delivery system for glucoseresponsive controlled release of insulin and cyclic AMP. J Am Chem Soc 2009; 131: 8398-400.
    • (2009) J Am Chem Soc , vol.131 , pp. 8398-8400
    • Zhao, Y.1    Trewyn, B.G.2    Slowing, I.I.3    Lin, V.S.-Y.4
  • 89
    • 54549109154 scopus 로고    scopus 로고
    • Release and molecular transport of cationic and anionic fluorescent molecules in mesoporous silica spheres
    • Ng JBS, Kamali-Zare P, Brismar H, Bergström L. Release and molecular transport of cationic and anionic fluorescent molecules in mesoporous silica spheres. Langmuir 2008; 24: 11096-102.
    • (2008) Langmuir , vol.24 , pp. 11096-11102
    • Ng, J.B.S.1    Kamali-Zare, P.2    Brismar, H.3    Bergström, L.4
  • 90
    • 34547822614 scopus 로고    scopus 로고
    • Diffusion-based deprotection in mesoporous materials: A strategy for differential functionalization of porous silica particles
    • Cheng K, Landry CC. Diffusion-based deprotection in mesoporous materials: a strategy for differential functionalization of porous silica particles. J Am Chem Soc 2007; 129: 9674-85.
    • (2007) J Am Chem Soc , vol.129 , pp. 9674-9685
    • Cheng, K.1    Landry, C.C.2
  • 91
    • 68949107601 scopus 로고    scopus 로고
    • Nanostructured silica materials as drug-delivery systems for doxorubicin: Single molecule and cellular studies
    • Lebold T, Jung C, Michaelis J, Bräuchle C. Nanostructured silica materials as drug-delivery systems for doxorubicin: single molecule and cellular studies. ACS Nano 2009; 9: 2877-83.
    • (2009) ACS Nano , vol.9 , pp. 2877-2883
    • Lebold, T.1    Jung, C.2    Michaelis, J.3    Bräuchle, C.4
  • 92
    • 57649244880 scopus 로고    scopus 로고
    • Tuning drug uptake and release rates through different morphologies and pore diameters of confined mesoporous silica
    • Cauda V, Muhlstein L, Onida B, Bein T. Tuning drug uptake and release rates through different morphologies and pore diameters of confined mesoporous silica. Microporous Mesoporous Mater 2009; 118: 435-42.
    • (2009) Microporous Mesoporous Mater , vol.118 , pp. 435-442
    • Cauda, V.1    Muhlstein, L.2    Onida, B.3    Bein, T.4
  • 93
    • 77950340684 scopus 로고    scopus 로고
    • Bio-degradation study of colloidal mesoporous silica nanoparticles: Effect of surface functionalization with organo-silanes and poly(ethylene glycol)
    • Cauda C, Schlossbauer A, Bein T. Bio-degradation study of colloidal mesoporous silica nanoparticles: Effect of surface functionalization with organo-silanes and poly(ethylene glycol). Microporous Mesoporous Mater 2010; 132: 60-71.
    • (2010) Microporous Mesoporous Mater , vol.132 , pp. 60-71
    • Cauda, C.1    Schlossbauer, A.2    Bein, T.3
  • 94
    • 72049121849 scopus 로고    scopus 로고
    • Pores occlusion in MCM-41 spheres immersed in SBF and the effect on ibuprofen delivery kinetics: A quantitative model
    • Mortera R, Fiorilli S, Garrone E, Verné E, Onida B. Pores occlusion in MCM-41 spheres immersed in SBF and the effect on ibuprofen delivery kinetics: A quantitative model. Chem Eng J 2010; 156: 184-92.
    • (2010) Chem Eng J , vol.156 , pp. 184-192
    • Mortera, R.1    Fiorilli, S.2    Garrone, E.3    Verné, E.4    Onida, B.5
  • 95
    • 73649097538 scopus 로고    scopus 로고
    • Intraparticle transport and release of dextran in silica spheres with cylindrical mesopores
    • Ng JBS, Kamali-Zare P, Sörensen M, Brismar H, Hedin N, Bergström L. Intraparticle transport and release of dextran in silica spheres with cylindrical mesopores. Langmuir 2010; 26: 466-70.
    • (2010) Langmuir , vol.26 , pp. 466-470
    • Ng, J.B.S.1    Kamali-Zare, P.2    Sörensen, M.3    Brismar, H.4    Hedin, N.5    Bergström, L.6
  • 96
    • 57349102539 scopus 로고    scopus 로고
    • Large antibiotic molecule diffusion in confined mesoporous silica with controlled morphology
    • Cauda V, Onida B, Platschek B, Mühlstein L, Bein T. Large antibiotic molecule diffusion in confined mesoporous silica with controlled morphology. J Mater Chem 2008; 18: 5888-99.
    • (2008) J Mater Chem , vol.18 , pp. 5888-5899
    • Cauda, V.1    Onida, B.2    Platschek, B.3    Mühlstein, L.4    Bein, T.5
  • 97
    • 77950168305 scopus 로고    scopus 로고
    • Mechanised nanoparticles for drug delivery
    • Cotí KK, Belowich ME, Liong M, et al. Mechanised nanoparticles for drug delivery. Nanoscale 2009; 1: 16-39.
    • (2009) Nanoscale , vol.1 , pp. 16-39
    • Cotí, K.K.1    Belowich, M.E.2    Liong, M.3
  • 98
    • 67649199464 scopus 로고    scopus 로고
    • Controlled release using mesoporous materials containing gate-like scaffoldings
    • Aznar E, Martínez-Mañez R, Sancenón F. Controlled release using mesoporous materials containing gate-like scaffoldings. Exp Op Drug Deliv 2009; 6: 643-55.
    • (2009) Exp Op Drug Deliv , vol.6 , pp. 643-655
    • Aznar, E.1    Martínez-Mañez, R.2    Sancenón, F.3
  • 99
    • 3242684047 scopus 로고    scopus 로고
    • Toward the development of ionically controlled nanoscopic molecular gates
    • Casasús R, Marcos MD, Martínez-Máñez R, et al. Toward the development of ionically controlled nanoscopic molecular gates. J Am Chem Soc 2004; 126: 8612-3.
    • (2004) J Am Chem Soc , vol.126 , pp. 8612-8613
    • Casasús, R.1    Marcos, M.D.2    Martínez-Máñez, R.3
  • 100
    • 54049149690 scopus 로고    scopus 로고
    • Controlled release of vitamin B-2 using mesoporous materials functionalized with amine-bearing gate-like scaffoldings
    • Bernardos A, Aznar E, Coll C, et al. Controlled release of vitamin B-2 using mesoporous materials functionalized with amine-bearing gate-like scaffoldings. J Control Release 2008; 131: 181-9.
    • (2008) J Control Release , vol.131 , pp. 181-189
    • Bernardos, A.1    Aznar, E.2    Coll, C.3
  • 101
    • 38949163631 scopus 로고    scopus 로고
    • pH-controllable drug release using hydrogel encapsulated mesoporous silica
    • Song S-W, Hidajat K, Kawi S. pH-controllable drug release using hydrogel encapsulated mesoporous silica. Chem Commun 2007; 4396-8.
    • (2007) Chem Commun , pp. 4396-4398
    • Song, S.-W.1    Hidajat, K.2    Kawi, S.3
  • 102
    • 68049132947 scopus 로고    scopus 로고
    • pH-Responsive drug release from polymer-coated mesoporous silica spheres
    • Gao Q, Xu Y, Wu D, Sun Y, Li X. pH-Responsive drug release from polymer-coated mesoporous silica spheres. J Phys Chem C 2009; 113: 12753-8.
    • (2009) J Phys Chem C , vol.113 , pp. 12753-12758
    • Gao, Q.1    Xu, Y.2    Wu, D.3    Sun, Y.4    Li, X.5
  • 103
    • 77952340878 scopus 로고    scopus 로고
    • A mesoporous silica nanoparticle with charge-convertible pore walls for efficient intracellular protein delivery
    • Park HS, Kim CW, Lee HJ, et al. A mesoporous silica nanoparticle with charge-convertible pore walls for efficient intracellular protein delivery. Nanotechnology 2010; 21: 225101 (9 pp).
    • (2010) Nanotechnology , vol.21
    • Park, H.S.1    Kim, C.W.2    Lee, H.J.3
  • 104
    • 28944440584 scopus 로고    scopus 로고
    • pH-responsive carrier system based on carboxylic acid modified mesoporous silica and polyelectrolyte for drug delivery
    • Yang Q, Wang S, Fan P, et al. pH-responsive carrier system based on carboxylic acid modified mesoporous silica and polyelectrolyte for drug delivery. Chem Mater 2005; 17: 5999-6003.
    • (2005) Chem Mater , vol.17 , pp. 5999-6003
    • Yang, Q.1    Wang, S.2    Fan, P.3
  • 105
    • 62149114161 scopus 로고    scopus 로고
    • Chitosan hydrogel-capped porous sio2 as a ph responsive nano-valve for triggered release of insulin
    • Wu J, Sailor M. Chitosan hydrogel-capped porous sio2 as a ph responsive nano-valve for triggered release of insulin. Adv Funct Mater 2009; 19: 733-41.
    • (2009) Adv Funct Mater , vol.19 , pp. 733-741
    • Wu, J.1    Sailor, M.2
  • 106
    • 69949123719 scopus 로고    scopus 로고
    • pH-responsive mechanised nanoparticles gated by semirotaxanes
    • Khashab NM, Belowich ME, Trabolsi A, et al. pH-responsive mechanised nanoparticles gated by semirotaxanes. Chem Commun 2009; 5371-3.
    • (2009) Chem Commun , pp. 5371-5373
    • Khashab, N.M.1    Belowich, M.E.2    Trabolsi, A.3
  • 107
    • 76149084184 scopus 로고    scopus 로고
    • pH responsive nanogated ensemble based on gold-capped mesoporous silica through an acid-labile acetal linker
    • Liu R, Zhang Y, Zhao X, Agarwal A, Mueller LJ, Feng P. pHResponsive nanogated ensemble based on gold-capped mesoporous silica through an acid-labile acetal linker. J Am Chem Soc 2010; 132: 1500-1.
    • (2010) J Am Chem Soc , vol.132 , pp. 1500-1501
    • Liu, R.1    Zhang, Y.2    Zhao, X.3    Agarwal, A.4    Mueller, L.J.5    Feng, P.6
  • 108
    • 0037448920 scopus 로고    scopus 로고
    • A mesoporous silica nanosphere-based carrier system with chemically removable cds nanoparticle caps for stimuli-responsive controlled release of neurotransmitters and drug molecules
    • Lai C-Y, Trewyn BG, Jeftinija DM, et al. A mesoporous silica nanosphere-based carrier system with chemically removable cds nanoparticle caps for stimuli-responsive controlled release of neurotransmitters and drug molecules. J Am Chem Soc 2003; 125: 4451-9.
    • (2003) J Am Chem Soc , vol.125 , pp. 4451-4459
    • Lai, C.-Y.1    Trewyn, B.G.2    Jeftinija, D.M.3
  • 109
    • 34250001748 scopus 로고    scopus 로고
    • Mesoporous silica nanoparticles deliver DNA and chemicals into plants
    • Torney F, Trewyn BG, Lin VS-Y, Wang K. Mesoporous silica nanoparticles deliver DNA and chemicals into plants. Nature Nanotechnol 2007; 2: 295-300.
    • (2007) Nature Nanotechnol , vol.2 , pp. 295-300
    • Torney, F.1    Trewyn, B.G.2    Lin, V.S.-Y.3    Wang, K.4
  • 110
    • 67650529515 scopus 로고    scopus 로고
    • pH- and photoswitched release of guest molecules from mesoporous silica supports
    • Aznar E, Marcos MD, Martinez-Máñez R, et al. pH- and photoswitched release of guest molecules from mesoporous silica supports. J Am Chem Soc 2009; 131: 6833-43.
    • (2009) J Am Chem Soc , vol.131 , pp. 6833-6843
    • Aznar, E.1    Marcos, M.D.2    Martinez-Máñez, R.3
  • 111
    • 23944437359 scopus 로고    scopus 로고
    • Stimuli-responsive controlled-release delivery system based on mesoporous silica nanorods capped with magnetic nanoparticles
    • Giri S, Trewyn BG, Stellmaker MP, Lin VS-Y. Stimuli-responsive controlled-release delivery system based on mesoporous silica nanorods capped with magnetic nanoparticles. Angew Chem Int Ed 2005; 44: 5038-44.
    • (2005) Angew Chem Int Ed , vol.44 , pp. 5038-5044
    • Giri, S.1    Trewyn, B.G.2    Stellmaker, M.P.3    Lin, V.S.-Y.4
  • 112
    • 33750594700 scopus 로고    scopus 로고
    • Switching catalytic reaction conducted in pore void of mesoporous material by redox gate control
    • Fujiwara M, Terashima S, Endo Y, Shiokawa K, Ohue H. Switching catalytic reaction conducted in pore void of mesoporous material by redox gate control. Chem Commun 2006; 4635-7.
    • (2006) Chem Commun , pp. 4635-4637
    • Fujiwara, M.1    Terashima, S.2    Endo, Y.3    Shiokawa, K.4    Ohue, H.5
  • 113
    • 55549106158 scopus 로고    scopus 로고
    • Tunable redox-responsive hybrid nanogated ensembles
    • Liu R, Zhao X, Wu T, Feng P. Tunable redox-responsive hybrid nanogated ensembles. J Am Chem Soc 2008; 130: 14418-9.
    • (2008) J Am Chem Soc , vol.130 , pp. 14418-14419
    • Liu, R.1    Zhao, X.2    Wu, T.3    Feng, P.4
  • 114
    • 70350077671 scopus 로고    scopus 로고
    • An efficient cell-targeting and intracellular controlled-release drug delivery system based on MSN-PEM-aptamer conjugates
    • Zhu C-L, Song X-Y, Zhou W-H, Yang H-H, Wen Y-H, Wang X-R. An efficient cell-targeting and intracellular controlled-release drug delivery system based on MSN-PEM-aptamer conjugates. J Mater Chem 2009; 19; 7765-70.
    • (2009) J Mater Chem , vol.19 , pp. 7765-7770
    • Zhu, C.-L.1    Song, X.-Y.2    Zhou, W.-H.3    Yang, H.-H.4    Wen, Y.-H.5    Wang, X.-R.6
  • 115
    • 39749150344 scopus 로고    scopus 로고
    • Enzyme-responsive snap-top covered silica nanocontainers
    • Patel K, Angelos S, Dichtel WR, et al. Enzyme-responsive snap-top covered silica nanocontainers. J Am Chem Soc 2008; 130: 2382-3.
    • (2008) J Am Chem Soc , vol.130 , pp. 2382-2383
    • Patel, K.1    Angelos, S.2    Dichtel, W.R.3
  • 116
    • 70450177494 scopus 로고    scopus 로고
    • Enzyme responsive nanocontainers with cyclodextrin gatekeepers and synergistic effects in release of guests
    • Park C, Kim H, Kim S, Kim C. Enzyme responsive nanocontainers with cyclodextrin gatekeepers and synergistic effects in release of guests. J Am Chem Soc 2009; 131: 16614-5.
    • (2009) J Am Chem Soc , vol.131 , pp. 16614-16615
    • Park, C.1    Kim, H.2    Kim, S.3    Kim, C.4
  • 117
    • 70349784859 scopus 로고    scopus 로고
    • Biotin-avidin as a proteaseresponsive cap system for controlled guest release from colloidal mesoporous silica
    • Schlossbauer A, Kecht J, Bein T. Biotin-avidin as a proteaseresponsive cap system for controlled guest release from colloidal mesoporous silica. Angew Chem Int Ed 2009; 48: 3092-5.
    • (2009) Angew Chem Int Ed , vol.48 , pp. 3092-3095
    • Schlossbauer, A.1    Kecht, J.2    Bein, T.3
  • 118
    • 70349623186 scopus 로고    scopus 로고
    • Controlled delivery systems using antibody-capped mesoporous nanocontainers
    • Climent E, Bernardos A, Martinez-Manez R, et al. controlled delivery systems using antibody-capped mesoporous nanocontainers. J Am Chem Soc 2009; 131: 14075-80.
    • (2009) J Am Chem Soc , vol.131 , pp. 14075-14080
    • Climent, E.1    Bernardos, A.2    Martinez-Manez, R.3
  • 119
    • 67650523182 scopus 로고    scopus 로고
    • Electrostatically mediated liposome fusion and lipid exchange with a nanoparticle-supported bilayer for control of surface charge, drug containment, and delivery
    • Liu J, Jiang X, Ashley C, Brinker CJ. Electrostatically mediated liposome fusion and lipid exchange with a nanoparticle-supported bilayer for control of surface charge, drug containment, and delivery. J Am Chem Soc 2009; 131: 7567-9.
    • (2009) J Am Chem Soc , vol.131 , pp. 7567-7569
    • Liu, J.1    Jiang, X.2    Ashley, C.3    Brinker, C.J.4
  • 121
    • 6044238264 scopus 로고    scopus 로고
    • A polyamidoamine dendrimer-capped mesoporous silica nanospherebased gene transfection reagent
    • Radu DR, Lai CY, Jeftinija K, Rowe EW, Jeftinija S, Lin VS-Y. A polyamidoamine dendrimer-capped mesoporous silica nanospherebased gene transfection reagent. J Am Chem Soc 2004; 126: 13216-7.
    • (2004) J Am Chem Soc , vol.126 , pp. 13216-13217
    • Radu, D.R.1    Lai, C.Y.2    Jeftinija, K.3    Rowe, E.W.4    Jeftinija, S.5    Lin, V.S.-Y.6
  • 122
    • 44749086164 scopus 로고    scopus 로고
    • Mannosylated polyethylenimine coupled mesoporous silica nanoparticles for receptor-mediated gene delivery
    • Park IY, Kim IY, Yoo MK, Choi YJ, Cho M-H, Cho CS. Mannosylated polyethylenimine coupled mesoporous silica nanoparticles for receptor-mediated gene delivery. Int J Pharm 2008; 359: 280-7.
    • (2008) Int J Pharm , vol.359 , pp. 280-287
    • Park, I.Y.1    Kim, I.Y.2    Yoo, M.K.3    Choi, Y.J.4    Cho, M.-H.5    Cho, C.S.6
  • 123
    • 77953168018 scopus 로고    scopus 로고
    • Mesoporous silica nanoparticles facilitate delivery of siRNA to shutdown signaling pathways in mammalian cells
    • Hom C, Lu J, Liong M, et al. Mesoporous silica nanoparticles facilitate delivery of siRNA to shutdown signaling pathways in mammalian cells. Small 2010; 6: 1185-90.
    • (2010) Small , vol.6 , pp. 1185-1190
    • Hom, C.1    Lu, J.2    Liong, M.3
  • 124
    • 60649089264 scopus 로고    scopus 로고
    • Effect of surface functionality of magnetic silica nanoparticles on the cellular uptake by glioma cells in vitro
    • Yu J, Zhao H, Ye L, et al. Effect of surface functionality of magnetic silica nanoparticles on the cellular uptake by glioma cells in vitro. J Mater Chem 2009; 19: 1265-70.
    • (2009) J Mater Chem , vol.19 , pp. 1265-1270
    • Yu, J.1    Zhao, H.2    Ye, L.3
  • 125
    • 75949111354 scopus 로고    scopus 로고
    • Surface activation and targeting strategies of superparamagnetic iron oxide nanoparticles in cancer-oriented diagnosis and therapy
    • Lin MM, Kim H-H, Kim H, Dobson J, Kim DK. Surface activation and targeting strategies of superparamagnetic iron oxide nanoparticles in cancer-oriented diagnosis and therapy. Nanomedicine 2010; 5: 109-33.
    • (2010) Nanomedicine , vol.5 , pp. 109-133
    • Lin, M.M.1    Kim, H.-H.2    Kim, H.3    Dobson, J.4    Kim, D.K.5
  • 126
    • 33846892018 scopus 로고    scopus 로고
    • Bifunctional magnetic silica nanoparticles for highly efficient human stem cell labeling
    • Lu C-W, Hung Y, Hsiao J-K, et al. Bifunctional magnetic silica nanoparticles for highly efficient human stem cell labeling. Nano Lett 2007; 7: 149.
    • (2007) Nano Lett , vol.7 , pp. 149
    • Lu, C.-W.1    Hung, Y.2    Hsiao, J.-K.3
  • 127
    • 33751037289 scopus 로고    scopus 로고
    • Multifunctional composite nanoparticles: Magnetic, luminescent, and mesoporous
    • Lin Y-S, Wu S-H, Hung Y, et al. Multifunctional composite nanoparticles: magnetic, luminescent, and mesoporous. Chem Mater 2006; 18: 5170-2.
    • (2006) Chem Mater , vol.18 , pp. 5170-5172
    • Lin, Y.-S.1    Wu, S.-H.2    Hung, Y.3
  • 128
    • 44949136246 scopus 로고    scopus 로고
    • Mesoporous silica nanoparticles improve magnetic labeling efficiency in human stem cells
    • Liu H-M, Wu S-H, Lu C-W, et al. Mesoporous silica nanoparticles improve magnetic labeling efficiency in human stem cells. Small 2008; 4: 619-26.
    • (2008) Small , vol.4 , pp. 619-626
    • Liu, H.-M.1    Wu, S.-H.2    Lu, C.-W.3
  • 129
    • 38149038610 scopus 로고    scopus 로고
    • Multifunctional mesoporous silica nanoparticles for intracellular labeling and animal magnetic resonance imaging studies
    • Wu S-H, Lin Y-S, Hung Y, et al. Multifunctional mesoporous silica nanoparticles for intracellular labeling and animal magnetic resonance imaging studies. Chem Bio Chem 2008; 9: 53-7.
    • (2008) Chem Bio Chem , vol.9 , pp. 53-57
    • Wu, S.-H.1    Lin, Y.-S.2    Hung, Y.3
  • 130
    • 6444225194 scopus 로고    scopus 로고
    • Gadolinium(III)-incorporated nanosized mesoporous silica as potential magnetic resonance imaging contrast agents
    • Lin Y-S, Hung Y, Su J-K, et al. Gadolinium(III)-incorporated nanosized mesoporous silica as potential magnetic resonance imaging contrast agents. J Phys Chem B 2004; 108: 15608-11.
    • (2004) J Phys Chem B , vol.108 , pp. 15608-15611
    • Lin, Y.-S.1    Hung, Y.2    Su, J.-K.3
  • 131
    • 39549093573 scopus 로고    scopus 로고
    • Mesoporous silica nanospheres as highly efficient MRI contrast agents
    • Taylor K-M, Kim J-S, Reiter W-J, An H, Lin W, Lin W. Mesoporous silica nanospheres as highly efficient MRI contrast agents. J Am Chem Soc 2008; 130: 2154-5.
    • (2008) J Am Chem Soc , vol.130 , pp. 2154-2155
    • Taylor, K.-M.1    Kim, J.-S.2    Reiter, W.-J.3    An, H.4    Lin, W.5    Lin, W.6
  • 132
    • 52649172803 scopus 로고    scopus 로고
    • Mesoporous silica nanoparticles as a delivery system of gadolinium for effective human stem cell tracking
    • Hsiao J-K, Tsai C-P, Chung T-H, et al. Mesoporous silica nanoparticles as a delivery system of gadolinium for effective human stem cell tracking. Small 2008; 4: 1445-52.
    • (2008) Small , vol.4 , pp. 1445-1452
    • Hsiao, J.-K.1    Tsai, C.-P.2    Chung, T.-H.3
  • 134
    • 25444455633 scopus 로고    scopus 로고
    • Well-ordered mesoporous silica nanoparticles as cell markers
    • Lin Y-S, Tsai C-P, Huang H-Y, et al. Well-ordered mesoporous silica nanoparticles as cell markers. Chem Mater 2005; 17: 4570-3.
    • (2005) Chem Mater , vol.17 , pp. 4570-4573
    • Lin, Y.-S.1    Tsai, C.-P.2    Huang, H.-Y.3
  • 135
    • 28744459447 scopus 로고    scopus 로고
    • Highly efficient cellular labeling of mesoporous nanoparticles in human mesenchymal stem cells: Implication for stem cell tracking
    • Huang D-M, Hung Y, Ko B-S, et al. Highly efficient cellular labeling of mesoporous nanoparticles in human mesenchymal stem cells: implication for stem cell tracking. FASEB J 2005; 19: 2014-6.
    • (2005) FASEB J , vol.19 , pp. 2014-2016
    • Huang, D.-M.1    Hung, Y.2    Ko, B.-S.3
  • 136
    • 58949102416 scopus 로고    scopus 로고
    • Near-infrared mesoporous silica nanoparticles for optical imaging: Characterization and in vivo biodistribution
    • Lee C-H, Cheng S-H, Wang Y-J, et al. Near-infrared mesoporous silica nanoparticles for optical imaging: characterization and in vivo biodistribution. Adv Funct Mater 2009; 19: 215-22.
    • (2009) Adv Funct Mater , vol.19 , pp. 215-222
    • Lee, C.-H.1    Cheng, S.-H.2    Wang, Y.-J.3
  • 137
    • 45749083773 scopus 로고    scopus 로고
    • Multifunctional inorganic nanoparticles for imaging, targeting, and drug delivery
    • Liong M, Lu J, Kovochich M, et al. Multifunctional Inorganic Nanoparticles for Imaging, Targeting, and Drug Delivery. ACS Nano 2008; 2: 889-96.
    • (2008) ACS Nano , vol.2 , pp. 889-896
    • Liong, M.1    Lu, J.2    Kovochich, M.3
  • 138
    • 74949092822 scopus 로고    scopus 로고
    • Uniform mesoporous dye-doped silica nanoparticles decorated with multiple magnetite nanocrystals for simultaneous enhanced magnetic resonance imaging, fluorescence imaging, and drug delivery
    • Lee J-E, Lee N, Kim H, et al. Uniform mesoporous dye-doped silica nanoparticles decorated with multiple magnetite nanocrystals for simultaneous enhanced magnetic resonance imaging, fluorescence imaging, and drug delivery. J Am Chem Soc 2010; 132: 552-7.
    • (2010) J Am Chem Soc , vol.132 , pp. 552-557
    • Lee, J.-E.1    Lee, N.2    Kim, H.3
  • 139
    • 34147144905 scopus 로고    scopus 로고
    • The effect of surface charge on the uptake and biological function of mesoporous silica nanoparticles in 3T3-L1 cells and human mesenchymal stem cells
    • Chung T-H, Wu S-H, Yao M, et al. The effect of surface charge on the uptake and biological function of mesoporous silica nanoparticles in 3T3-L1 cells and human mesenchymal stem cells. Biomaterials 2007; 28: 2959-66.
    • (2007) Biomaterials , vol.28 , pp. 2959-2966
    • Chung, T.-H.1    Wu, S.-H.2    Yao, M.3
  • 140
    • 67650338048 scopus 로고    scopus 로고
    • Size effect on cell uptake in well-suspended, uniform mesoporous silica nanoparticles
    • Lu F, Wu S-H, Hung Y, Mou C-Y. Size effect on cell uptake in well-suspended, uniform mesoporous silica nanoparticles. Small 2009; 5: 1408-13.
    • (2009) Small , vol.5 , pp. 1408-1413
    • Lu, F.1    Wu, S.-H.2    Hung, Y.3    Mou, C.-Y.4
  • 142
    • 67349180163 scopus 로고    scopus 로고
    • Mesoporous silica nanoparticles enhance MTT formazan exocytosis in HeLa cells and astrocytes
    • Fisichella M, Dabboue H, Bhattacharyya S, et al. Mesoporous silica nanoparticles enhance MTT formazan exocytosis in HeLa cells and astrocytes. Toxicology in vitro 2009; 23: 697.
    • (2009) Toxicology in Vitro , vol.23 , pp. 697
    • Fisichella, M.1    Dabboue, H.2    Bhattacharyya, S.3
  • 143
    • 35348983485 scopus 로고    scopus 로고
    • Synthesis and functionalization of a mesoporous silica nanoparticle based on the sol-gel process and applications in controlled release
    • Trewyn B-G, Slowing I-I, Giri S, Chen H-T, Lin V S-Y. synthesis and functionalization of a mesoporous silica nanoparticle based on the sol-gel process and applications in controlled release. Acc Chem Res 2007; 40: 846-53.
    • (2007) Acc Chem Res , vol.40 , pp. 846-853
    • Trewyn, B.-G.1    Slowing, I.-I.2    Giri, S.3    Chen, H.-T.4    Lin, V.S.-Y.5
  • 144
    • 44649100271 scopus 로고    scopus 로고
    • Cytotoxicity of mesoporous silica nanomaterials
    • Di Pasqua A-J, Sharma K-K, Shi Y-L, et al. Cytotoxicity of mesoporous silica nanomaterials. J Inorg Biochem 2008; 102: 1416-23.
    • (2008) J Inorg Biochem , vol.102 , pp. 1416-1423
    • di Pasqua, A.-J.1    Sharma, K.-K.2    Shi, Y.-L.3
  • 145
    • 72749119676 scopus 로고    scopus 로고
    • Mesoporosity and functional group dependent endocytosis and cytotoxicity of silica nanomaterials
    • Tao Z, Toms BB, Goodisman J, Asefa T. Mesoporosity and Functional Group Dependent Endocytosis and Cytotoxicity of Silica Nanomaterials. Chem Res Toxicol 2009; 22: 1869-80.
    • (2009) Chem Res Toxicol , vol.22 , pp. 1869-1880
    • Tao, Z.1    Toms, B.B.2    Goodisman, J.3    Asefa, T.4
  • 146
    • 77957893294 scopus 로고    scopus 로고
    • Towards multifunctional, targeted drug delivery systems using mesoporous silica nanoparticles - opportunities & challenges
    • Rosenholm JM, Sahlgren C, Lindén M. Towards multifunctional, targeted drug delivery systems using mesoporous silica nanoparticles - opportunities & challenges. Nanoscale 2010; 2: 1870-83.
    • (2010) Nanoscale , vol.2 , pp. 1870-1883
    • Rosenholm, J.M.1    Sahlgren, C.2    Lindén, M.3
  • 148
    • 67650229580 scopus 로고    scopus 로고
    • The impact of size on tissue distribution and elimination by single intravenous injection of silica nanoparticles
    • Cho M, Cho WS, Choi M, et al. The impact of size on tissue distribution and elimination by single intravenous injection of silica nanoparticles. Toxicol Lett 2009; 189: 177-83.
    • (2009) Toxicol Lett , vol.189 , pp. 177-183
    • Cho, M.1    Cho, W.S.2    Choi, M.3
  • 149
    • 14644439267 scopus 로고    scopus 로고
    • Cancer nanotechnology: Opportunities and challenges
    • Ferrari M. Cancer nanotechnology: opportunities and challenges. Nat Rev Cancer 2005; 5: 161-71.
    • (2005) Nat Rev Cancer , vol.5 , pp. 161-171
    • Ferrari, M.1
  • 150
    • 51049090204 scopus 로고    scopus 로고
    • Nanoparticle therapeutics: An emerging treatment modality for cancer
    • Davis ME, Chen ZG, Shin DM. Nanoparticle therapeutics: an emerging treatment modality for cancer. Nat Rev Drug Discov 2008; 7: 771-82.
    • (2008) Nat Rev Drug Discov , vol.7 , pp. 771-782
    • Davis, M.E.1    Chen, Z.G.2    Shin, D.M.3
  • 151
    • 0037120096 scopus 로고    scopus 로고
    • Simultaneous immobilization of horseradish peroxidase and glucose oxidase in mesoporous Sol- Gel host materials
    • Wei Y, Dong H, Xu J, Feng Q. Simultaneous Immobilization of Horseradish Peroxidase and Glucose Oxidase in Mesoporous Sol- Gel Host Materials. ChemPhysChem 2002; 3: 802-8.
    • (2002) ChemPhysChem , vol.3 , pp. 802-808
    • Wei, Y.1    Dong, H.2    Xu, J.3    Feng, Q.4
  • 152
    • 1042264194 scopus 로고    scopus 로고
    • Direct electron transfer and enzymatic activity of hemoglobin in a hexagonal mesoporous silica matrix
    • Dai Z, Liu S, Ju H, Chen H. Direct electron transfer and enzymatic activity of hemoglobin in a hexagonal mesoporous silica matrix. Biosens Bioelectron 2004; 19: 861-7.
    • (2004) Biosens Bioelectron , vol.19 , pp. 861-867
    • Dai, Z.1    Liu, S.2    Ju, H.3    Chen, H.4
  • 153
    • 4143148668 scopus 로고    scopus 로고
    • Direct electrochemistry and electrocatalysis of myoglobin immobilized on a hexagonal mesoporous silica matrix
    • Dai ZH, Xu XX, Ju HX. Direct electrochemistry and electrocatalysis of myoglobin immobilized on a hexagonal mesoporous silica matrix. Anal Biochem 2004; 332: 23-31.
    • (2004) Anal Biochem , vol.332 , pp. 23-31
    • Dai, Z.H.1    Xu, X.X.2    Ju, H.X.3
  • 154
    • 1242269273 scopus 로고    scopus 로고
    • Gatekeeping layer effect: A poly(lactic acid)-coated mesoporous silica nanosphere- based fluorescence probe for detection of amino-containing neurotransmitters
    • Radu DR, Lai CY, Wiench JW, Pruski M, Lin VS. Gatekeeping layer effect: a poly(lactic acid)-coated mesoporous silica nanosphere- based fluorescence probe for detection of amino-containing neurotransmitters. J Am Chem Soc 2004; 126: 1640-1.
    • (2004) J Am Chem Soc , vol.126 , pp. 1640-1641
    • Radu, D.R.1    Lai, C.Y.2    Wiench, J.W.3    Pruski, M.4    Lin, V.S.5
  • 155
    • 36248993858 scopus 로고    scopus 로고
    • Mesoporous silica materials with covalently anchored phenoxazinone dyes as fluorescent hybrid materials for vapour sensing
    • Descalzo AB, Marcos MD, Monte C, Martínez-Máñez R, Rurack K. Mesoporous silica materials with covalently anchored phenoxazinone dyes as fluorescent hybrid materials for vapour sensing. J Mater Chem 2007; 44: 4716-23.
    • (2007) J Mater Chem , vol.44 , pp. 4716-4723
    • Descalzo, A.B.1    Marcos, M.D.2    Monte, C.3    Martínez-Máñez, R.4    Rurack, K.5
  • 156
    • 34547838187 scopus 로고    scopus 로고
    • Mesoporous silica nanoparticles as a delivery system for hydrophobic anticancer drugs
    • Lu J, Liong M, Zink JI, Tamanoi F. Mesoporous silica nanoparticles as a delivery system for hydrophobic anticancer drugs. Small 2007; 3: 1341-6.
    • (2007) Small , vol.3 , pp. 1341-1346
    • Lu, J.1    Liong, M.2    Zink, J.I.3    Tamanoi, F.4
  • 157
    • 70249139149 scopus 로고    scopus 로고
    • Photoinduced intracellular controlled release drug delivery in human cells by gold-capped mesoporous silica nanosphere
    • Vivero-Escoto JL, Slowing II, Wu C-W, Lin VS-Y. Photoinduced intracellular controlled release drug delivery in human cells by gold-capped mesoporous silica nanosphere. J Am Chem Soc 2009; 131: 3462-3.
    • (2009) J Am Chem Soc , vol.131 , pp. 3462-3463
    • Vivero-Escoto, J.L.1    Slowing, I.I.2    Wu, C.-W.3    Lin, V.S.-Y.4
  • 158
    • 42049085288 scopus 로고    scopus 로고
    • Mesoporous silica nanoparticles for cancer therapy: Energy-dependent cellular uptake and delivery of paclitaxel to cancer cells
    • Lu J, Liong M, Sherman S, et al. Mesoporous silica nanoparticles for cancer therapy: energy-dependent cellular uptake and delivery of paclitaxel to cancer cells. Nanobiotechnol 2007; 3: 89-95.
    • (2007) Nanobiotechnol , vol.3 , pp. 89-95
    • Lu, J.1    Liong, M.2    Sherman, S.3
  • 159
    • 0034019945 scopus 로고    scopus 로고
    • Cationic polymer based gene delivery systems
    • De Smedt SC, Demeester J, Hennink WE. Cationic polymer based gene delivery systems. Pharm Res 2000; 17: 113-26.
    • (2000) Pharm Res , vol.17 , pp. 113-126
    • de Smedt, S.C.1    Demeester, J.2    Hennink, W.E.3
  • 160
    • 68549134917 scopus 로고    scopus 로고
    • Degradable, antibacterial silver exchanged mesoporous silica spheres for hemorrhage control
    • Dai C, Yuan Y, Liu C, et al. Degradable, antibacterial silver exchanged mesoporous silica spheres for hemorrhage control. Biomaterials 2009: 30; 5364-74.
    • (2009) Biomaterials , vol.30 , pp. 5364-5374
    • Dai, C.1    Yuan, Y.2    Liu, C.3
  • 161
    • 41549142680 scopus 로고    scopus 로고
    • Increasing the oral bioavailability of the poorly water soluble drug itraconazole with ordered mesoporous silica
    • Mellaerts R, Mols R, Jammaer JAG, et al. Increasing the oral bioavailability of the poorly water soluble drug itraconazole with ordered mesoporous silica. Eur J Pharm Biopharm 2008; 69: 223.
    • (2008) Eur J Pharm Biopharm , vol.69 , pp. 223
    • Mellaerts, R.1    Mols, R.2    Jammaer, J.A.G.3
  • 162
    • 61849111778 scopus 로고    scopus 로고
    • Mannose-targeted mesoporous silica nanoparticles for photodynamic therapy
    • Brevet D, Gary-Bobo M, Raehm L, et al. Mannose-targeted mesoporous silica nanoparticles for photodynamic therapy. Chem Commun 2009; 1475-7.
    • (2009) Chem Commun , pp. 1475-1477
    • Brevet, D.1    Gary-Bobo, M.2    Raehm, L.3
  • 163
    • 35248858366 scopus 로고    scopus 로고
    • Organic-inorganic mesoporous nanocarriers integrated with biogenic ligands
    • Gu J, Fan W, Shimojima A, Okubo T. Organic-inorganic mesoporous nanocarriers integrated with biogenic ligands. Small 2007; 3: 1740-4.
    • (2007) Small , vol.3 , pp. 1740-1744
    • Gu, J.1    Fan, W.2    Shimojima, A.3    Okubo, T.4
  • 164
    • 33845231619 scopus 로고    scopus 로고
    • Effect of Surface Functionalization of MCM-41-type mesoporous silica nanoparticles on the endocytosis by human cancer cells
    • Slowing I, Trewyn BG, Lin VS-Y. Effect of Surface Functionalization of MCM-41-type mesoporous silica nanoparticles on the endocytosis by human cancer cells. J Am Chem Soc 2006; 128: 14792-3.
    • (2006) J Am Chem Soc , vol.128 , pp. 14792-14793
    • Slowing, I.1    Trewyn, B.G.2    Lin, V.S.-Y.3
  • 165
    • 61849185277 scopus 로고    scopus 로고
    • Targeting of porous hybrid silica nanoparticles to cancer cells
    • Rosenholm JM, Meinander A, Peuhu E, et al. Targeting of porous hybrid silica nanoparticles to cancer cells. ACS Nano, 2009; 3: 197-206.
    • (2009) ACS Nano , vol.3 , pp. 197-206
    • Rosenholm, J.M.1    Meinander, A.2    Peuhu, E.3
  • 166
    • 68349141561 scopus 로고    scopus 로고
    • Monoclonal antibody-functionalized mesoporous silica nanoparticles (MSN) for selective targeting breast cancer cells
    • Tsai C-P, Chen C-Y, Hung Y, Chang F-H, Mou C-Y. Monoclonal antibody-functionalized mesoporous silica nanoparticles (MSN) for selective targeting breast cancer cells. J Mater Chem 2009; 19: 5737-43.
    • (2009) J Mater Chem , vol.19 , pp. 5737-5743
    • Tsai, C.-P.1    Chen, C.-Y.2    Hung, Y.3    Chang, F.-H.4    Mou, C.-Y.5
  • 167
    • 58449123317 scopus 로고    scopus 로고
    • In vitro studies of functionalized mesoporous silica nanoparticles for photodynamic therapy
    • Tu H-L, Lin Y-S, Lin H-Y, et al. In vitro studies of functionalized mesoporous silica nanoparticles for photodynamic therapy. Adv Mater 2009; 21: 172-4.
    • (2009) Adv Mater , vol.21 , pp. 172-174
    • Tu, H.-L.1    Lin, Y.-S.2    Lin, H.-Y.3
  • 168
    • 60749090668 scopus 로고    scopus 로고
    • Mesoporous silica nanoparticles functionalized with an oxygensensing probe for cell photodynamic therapy: Potential cancer theranostics
    • Cheng SH, Lee C-H, Yang C-S, Tseng F-G, Mou C-Y, Lo L-W. Mesoporous silica nanoparticles functionalized with an oxygensensing probe for cell photodynamic therapy: potential cancer theranostics J Mater Chem 2009; 19: 1252-7.
    • (2009) J Mater Chem , vol.19 , pp. 1252-1257
    • Cheng, S.H.1    Lee, C.-H.2    Yang, C.-S.3    Tseng, F.-G.4    Mou, C.-Y.5    Lo, L.-W.6


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