Inhibition of ulcerative colitis in mice after oral administration of a polyphenol-enriched cocoa extract is mediated by the inhibition of STAT1 and STAT3 phosphorylation in colon cells

Journal of Agricultural and Food Chemistry

Volumn 59, Issue 12, 2011, Pages 6474-6483

  Andújar, Isabel ^a   Recio, M Carmen ^a   Giner, Rosa M ^a   Cienfuegos Jovellanos, Elena ^b   Laghi, Sara ^b   Muguerza, Begoña ^b   Ríos, José Luis ^a  

^a UNIVERSITY OF VALENCIA   (Spain)

^b Natraceutical Group   (Spain)

Author keywords

cocoa; inflammatory bowel disease; polyphenols; Theobroma cacao; ulcerative colitis

Indexed keywords

ANTI-INFLAMMATORIES; COLON CELLS; CYCLOOXYGENASE 2; DEXTRAN SULFATE SODIUM; EPICATECHIN; EX-VIVO; IN-VITRO; INFLAMMATORY BOWEL DISEASE; INHIBITORY EFFECT; INTESTINAL CELLS; ORAL ADMINISTRATION; PHENOLICS; POLYPHENOLS; PROCYANIDINS; THEOBROMA CACAO; ULCERATIVE COLITIS;

DISEASES; MAMMALS; NITRIC OXIDE; PHENOLS; PHOSPHORYLATION; SODIUM; SODIUM SULFATE; TRANSCRIPTION FACTORS;

COCOA;

FLAVONOID; PHENOL DERIVATIVE; PLANT EXTRACT; POLYPHENOLS; STAT1 PROTEIN; STAT3 PROTEIN;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; CACAO; CELL LINE; CHEMISTRY; DISEASE MODEL; DOWN REGULATION; DRUG EFFECT; FEMALE; GENETICS; HUMAN; METABOLISM; MOUSE; PHOSPHORYLATION; ULCERATIVE COLITIS;

ANIMALS; CACAO; CELL LINE; COLITIS, ULCERATIVE; DISEASE MODELS, ANIMAL; DOWN-REGULATION; FEMALE; FLAVONOIDS; HUMANS; MICE; MICE, INBRED BALB C; PHENOLS; PHOSPHORYLATION; PLANT EXTRACTS; STAT1 TRANSCRIPTION FACTOR; STAT3 TRANSCRIPTION FACTOR;

MUS; THEOBROMA CACAO;

EID: 79959312370     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf2008925     Document Type: Article

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