-
1
-
-
0344622606
-
The serial cultivation of human diploid cell strains
-
Hayflick L, Moorhead PS: The serial cultivation of human diploid cell strains. Exp Cell Res 1961, 25:585-621
-
(1961)
Exp Cell Res
, vol.25
, pp. 585-621
-
-
Hayflick, L.1
Moorhead, P.S.2
-
2
-
-
0030944985
-
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16(INK4a)
-
DOI 10.1016/S0092-8674(00)81902-9
-
Serrano M, Lin AW, McCurrach ME, Beach D, Lowe SW: Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell 1997, 88:593-602 (Pubitemid 27152402)
-
(1997)
Cell
, vol.88
, Issue.5
, pp. 593-602
-
-
Serrano, M.1
Lin, A.W.2
McCurrach, M.E.3
Beach, D.4
Lowe, S.W.5
-
3
-
-
0038457477
-
Human melanocyte senescence and melanoma susceptibility genes
-
Bennett DC: Human melanocyte senescence and melanoma susceptibility genes. Oncogene 2003, 22:3063-3069
-
(2003)
Oncogene
, vol.22
, pp. 3063-3069
-
-
Bennett, D.C.1
-
5
-
-
0032907528
-
Cellular senescence and cancer
-
Wynford-Thomas D: Cellular senescence and cancer. J Pathol 1999, 187:100-111
-
(1999)
J Pathol
, vol.187
, pp. 100-111
-
-
Wynford-Thomas, D.1
-
6
-
-
23244447893
-
Tumour biology: Senescence in premalignant tumours
-
DOI 10.1038/436642a
-
Collado M, Gil J, Efeyan A, Guerra C, Schuhmacher AJ, Barradas M, Benguria A, Zaballos A, Flores JM, Barbacid M, Beach D, Serrano M: Tumour biology: senescence in premalignant tumours. Nature 2005, 436:642 (Pubitemid 41117258)
-
(2005)
Nature
, vol.436
, Issue.7051
, pp. 642
-
-
Collado, M.1
Gil, J.2
Efeyan, A.3
Guerra, C.4
Schuhmacher, A.J.5
Barradas, M.6
Benguria, A.7
Zaballos, A.8
Flores, J.M.9
Barbacid, M.10
Beach, D.11
Serrano, M.12
-
7
-
-
33747192833
-
Cellular senescence in naevi and immortalisation in melanoma: A role for p16?
-
DOI 10.1038/sj.bjc.6603283, PII 6603283
-
Gray-Schopfer VC, Cheong SC, Chong H, Chow J, Moss T, Abdel-Malek ZA, Marais R, Wynford-Thomas D, Bennett DC: Cellular senescence in naevi and immortalisation in melanoma: a role for p16? Br J Cancer 2006, 95:496-505 (Pubitemid 44232559)
-
(2006)
British Journal of Cancer
, vol.95
, Issue.4
, pp. 496-505
-
-
Gray-Schopfer, V.C.1
Cheong, S.C.2
Chong, H.3
Chow, J.4
Moss, T.5
Abdel-Malek, Z.A.6
Marais, R.7
Wynford-Thomas, D.8
Bennett, D.C.9
-
8
-
-
23244447037
-
E600-associated senescence-like cell cycle arrest of human naevi
-
DOI 10.1038/nature03890
-
Michaloglou C, Vredeveld LC, Soengas MS, Denoyelle C, Kuilman T, van der Horst CM, Majoor DM, Shay JW, Mooi WJ, Peeper DS: BRAFE600-associated senescence-like cell cycle arrest of human naevi. Nature 2005, 436:720-724 (Pubitemid 41117276)
-
(2005)
Nature
, vol.436
, Issue.7051
, pp. 720-724
-
-
Michaloglou, C.1
Vredeveld, L.C.W.2
Soengas, M.S.3
Denoyelle, C.4
Kuilman, T.5
Van Der, H.C.M.A.M.6
Majoor, D.M.7
Shay, J.W.8
Mooi, W.J.9
Peeper, D.S.10
-
9
-
-
47749139666
-
Melanomagenesis: Overcoming the barrier of melanocyte senescence
-
Ha L, Merlino G, Sviderskaya EV: Melanomagenesis: overcoming the barrier of melanocyte senescence. Cell Cycle 2008, 7:1944-1948 (Pubitemid 352030338)
-
(2008)
Cell Cycle
, vol.7
, Issue.13
, pp. 1944-1948
-
-
Ha, L.1
Merlino, G.2
Sviaerskaya, E.V.3
-
10
-
-
0035817687
-
Ink4a confers susceptibility to metastatic melanoma in mice
-
DOI 10.1038/35092584
-
Krimpenfort P, Quon KC, Mooi WJ, Loonstra A, Berns A: Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice. Nature 2001, 413:83-86 (Pubitemid 32843492)
-
(2001)
Nature
, vol.413
, Issue.6851
, pp. 83-86
-
-
Krimpenfort, P.1
Quon, K.C.2
Mooi, W.J.3
Loonstra, A.4
Berns, A.5
-
11
-
-
0037228055
-
High frequency of BRAF mutations in nevi
-
DOI 10.1038/ng1054
-
Pollock PM, Harper UL, Hansen KS, Yudt LM, Stark M, Robbins CM, Moses TY, Hostetter G, Wagner U, Kakareka J, Salem G, Pohida T, Heenan P, Duray P, Kallioniemi O, Hayward NK, Trent JM, Meltzer PS: High frequency of BRAF mutations in nevi. Nat Genet 2003, 33:19-20 (Pubitemid 36068675)
-
(2003)
Nature Genetics
, vol.33
, Issue.1
, pp. 19-20
-
-
Pollock, P.M.1
Harper, U.L.2
Hansen, K.S.3
Yudt, L.M.4
Stark, M.5
Robbins, C.M.6
Moses, T.Y.7
Hostetter, G.8
Wagner, U.9
Kakareka, J.10
Salem, G.11
Pohida, T.12
Heenan, P.13
Duray, P.14
Kallioniemi, O.15
Hayward, N.K.16
Trent, J.M.17
Meltzer, P.S.18
-
12
-
-
18444374405
-
Mutations of the BRAF gene in human cancer
-
DOI 10.1038/nature00766
-
Davies H, Bignell GR, Cox C, Stephens P, Edkins S, Clegg S, et al: Mutations of the BRAF gene in human cancer. Nature 2002, 417: 949-954 (Pubitemid 34716871)
-
(2002)
Nature
, vol.417
, Issue.6892
, pp. 949-954
-
-
Davies, H.1
Bignell, G.R.2
Cox, C.3
Stephens, P.4
Edkins, S.5
Clegg, S.6
Teague, J.7
Woffendin, H.8
Garnett, M.J.9
Bottomley, W.10
Davis, N.11
Dicks, E.12
Ewing, R.13
Floyd, Y.14
Gray, K.15
Hall, S.16
Hawes, R.17
Hughes, J.18
Kosmidou, V.19
Menzies, A.20
Mould, C.21
Parker, A.22
Stevens, C.23
Watt, S.24
Hooper, S.25
Wilson, R.26
Jayatilake, H.27
Gusterson, B.A.28
Cooper, C.29
Shipley, J.30
Hargrave, D.31
Pritchard-Jones, K.32
Maitland, N.33
Chenevix-Trench, G.34
Riggins, G.J.35
Bigner, D.D.36
Palmleri, G.37
Cossu, A.38
Flanagan, A.39
Nicholson, A.40
Ho, J.W.C.41
Leung, S.Y.42
Yuen, S.T.43
Weber, B.L.44
Seigler, H.F.45
Darrow, T.L.46
Paterson, H.47
Marais, R.48
Marshall, C.J.49
Wooster, R.50
Stratton, M.R.51
Futreal, P.A.52
more..
-
13
-
-
63249105225
-
Oncogenic Braf induces melanocyte senescence and melanoma in mice
-
Dhomen N, Reis-Filho JS, da Rocha Dias S, Hayward R, Savage K, Delmas V, Larue L, Pritchard C, Marais R: Oncogenic Braf induces melanocyte senescence and melanoma in mice. Cancer Cell 2009, 15:294-303
-
(2009)
Cancer Cell
, vol.15
, pp. 294-303
-
-
Dhomen, N.1
Reis-Filho, J.S.2
Da Rocha Dias, S.3
Hayward, R.4
Savage, K.5
Delmas, V.6
Larue, L.7
Pritchard, C.8
Marais, R.9
-
14
-
-
0347093303
-
Crystal structure of human pirin: An iron-binding nuclear protein and transcription cofactor
-
DOI 10.1074/jbc.M310022200
-
Pang H, Bartlam M, Zeng Q, Miyatake H, Hisano T, Miki K, Wong LL, Gao GF, Rao Z: Crystal structure of human pirin: an iron-binding nuclear protein and transcription cofactor. J Biol Chem 2004, 279: 1491-1498 (Pubitemid 38082678)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.2
, pp. 1491-1498
-
-
Pang, H.1
Bartlam, M.2
Zeng, Q.3
Miyatake, H.4
Hisano, T.5
Miki, K.6
Wong, L.-L.7
Gao, G.F.8
Rao, Z.9
-
15
-
-
0030934188
-
Identification of Pirin, a novel highly conserved nuclear protein
-
DOI 10.1074/jbc.272.13.8482
-
Wendler WM, Kremmer E, Forster R, Winnacker EL: Identification of pirin, a novel highly conserved nuclear protein. J Biol Chem 1997, 272:8482-8489 (Pubitemid 27147811)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.13
, pp. 8482-8489
-
-
Wendler, W.M.F.1
Kremmer, E.2
Forster, R.3
Winnacker, E.-L.4
-
16
-
-
77955924828
-
A small-molecule inhibitor shows that pirin regulates migration of melanoma cells
-
Miyazaki I, Simizu S, Okumura H, Takagi S, Osada H: A small-molecule inhibitor shows that pirin regulates migration of melanoma cells. Nat Chem Biol 6:667-673
-
Nat Chem Biol
, vol.6
, pp. 667-673
-
-
Miyazaki, I.1
Simizu, S.2
Okumura, H.3
Takagi, S.4
Osada, H.5
-
17
-
-
23344439806
-
Structural and biochemical analysis reveal Pirins to possess quercetinase activity
-
DOI 10.1074/jbc.M501034200
-
Adams M, Jia Z: Structural and biochemical analysis reveal pirins to possess quercetinase activity. J Biol Chem 2005, 280:28675-28682 (Pubitemid 41105768)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.31
, pp. 28675-28682
-
-
Adams, M.1
Jia, Z.2
-
18
-
-
59949097978
-
Upregulation of pirin expression by chronic cigarette smoking is associated with bronchial epithelial cell apoptosis
-
Gelbman BD, Heguy A, O'Connor TP, Zabner J, Crystal RG: Upregulation of pirin expression by chronic cigarette smoking is associated with bronchial epithelial cell apoptosis. Respir Res 2007, 8:10
-
(2007)
Respir Res
, vol.8
, pp. 10
-
-
Gelbman, B.D.1
Heguy, A.2
O'Connor, T.P.3
Zabner, J.4
Crystal, R.G.5
-
19
-
-
0034920639
-
A tomato homologue of the human protein PIRIN is induced during programmed cell death
-
DOI 10.1023/A:1010618515051
-
Orzaez D, de Jong AJ, Woltering EJ: A tomato homologue of the human protein PIRIN is induced during programmed cell death. Plant Mol Biol 2001, 46:459-468 (Pubitemid 32665070)
-
(2001)
Plant Molecular Biology
, vol.46
, Issue.4
, pp. 459-468
-
-
Orzaez, D.1
De Jong, A.J.2
Woltering, E.J.3
-
20
-
-
33748058131
-
Frequent alterations in the expression of serine/threonine kinases in human cancers
-
DOI 10.1158/0008-5472.CAN-05-3489
-
Capra M, Nuciforo PG, Confalonieri S, Quarto M, Bianchi M, Nebuloni M, Boldorini R, Pallotti F, Viale G, Gishizky ML, Draetta GF, Di Fiore PP: Frequent alterations in the expression of serine/threonine kinases in human cancers. Cancer Res 2006, 66:8147-8154 (Pubitemid 44299182)
-
(2006)
Cancer Research
, vol.66
, Issue.16
, pp. 8147-8154
-
-
Capra, M.1
Nuciforo, P.G.2
Confalonieri, S.3
Quarto, M.4
Bianchi, M.5
Nebuloni, M.6
Boldorini, R.7
Pallotti, F.8
Viale, G.9
Gishizky, M.L.10
Draetta, G.F.11
Di, F.P.P.12
-
21
-
-
17844406903
-
Up-regulated expression of zonula occludens protein-1 in human melanoma associates with N-cadherin and contributes to invasion and adhesion
-
Smalley KS, Brafford P, Haass NK, Brandner JM, Brown E, Herlyn M: Up-regulated expression of zonula occludens protein-1 in human melanoma associates with N-cadherin and contributes to invasion and adhesion. Am J Pathol 2005, 166:1541-1554 (Pubitemid 40586522)
-
(2005)
American Journal of Pathology
, vol.166
, Issue.5
, pp. 1541-1554
-
-
Smalley, K.S.M.1
Brafford, P.2
Haass, N.K.3
Brandner, J.M.4
Brown, E.5
Herlyn, M.6
-
22
-
-
34248144306
-
RaLP, a new member of the Src homology and collagen family, regulates cell migration and tumor growth of metastatic melanomas
-
DOI 10.1158/0008-5472.CAN-06-2301
-
Fagiani E, Giardina G, Luzi L, Cesaroni M, Quarto M, Capra M, Germano G, Bono M, Capillo M, Pelicci P, Lanfrancone L: RaLP, a new member of the Src homology and collagen family, regulates cell migration and tumor growth of metastatic melanomas. Cancer Res 2007, 67:3064-3073 (Pubitemid 46724843)
-
(2007)
Cancer Research
, vol.67
, Issue.7
, pp. 3064-3073
-
-
Fagiani, E.1
Giardina, G.2
Luzi, L.3
Cesaroni, M.4
Quarto, M.5
Capra, M.6
Germano, G.7
Bono, M.8
Capillo, M.9
Pelicci, P.10
Lanfrancone, L.11
-
23
-
-
3142708570
-
Cre-lox-regulated conditional RNA interference from transgenes
-
DOI 10.1073/pnas.0403954101
-
Ventura A, Meissner A, Dillon CP, McManus M, Sharp PA, Van Parijs L, Jaenisch R, Jacks T: Cre-lox-regulated conditional RNA interference from transgenes. Proc Natl Acad Sci USA 2004, 101:10380-10385 (Pubitemid 38924934)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.28
, pp. 10380-10385
-
-
Ventura, A.1
Meissner, A.2
Dillon, C.P.3
McManus, M.4
Sharp, P.A.5
Van Parijs, L.6
Jaenisch, R.7
Jacks, T.8
-
24
-
-
0031984816
-
High-efficiency gene transfer and selection of human hematopoietic progenitor cells with a hybrid EBV/retroviral vector expressing the green fluorescence protein
-
Grignani F, Kinsella T, Mencarelli A, Valtieri M, Riganelli D, Lanfrancone L, Peschle C, Nolan GP, Pelicci PG: High-efficiency gene transfer and selection of human hematopoietic progenitor cells with a hybrid EBV/retroviral vector expressing the green fluorescence protein. Cancer Res 1998, 58:14-19 (Pubitemid 28027708)
-
(1998)
Cancer Research
, vol.58
, Issue.1
, pp. 14-19
-
-
Grignani, F.1
Kinsella, T.2
Mencarelli, A.3
Valtieri, M.4
Riganelli, D.5
Grignani, F.6
Lanfrancone, L.7
Peschle, C.8
Nolan, G.P.9
Pelicci, P.G.10
-
25
-
-
0016766176
-
Tumor thickness, level of invasion and node dissection in stage I cutaneous melanoma
-
Breslow A: Tumor thickness, level of invasion and node dissection in stage I cutaneous melanoma. Ann Surg 1975, 182:572-575
-
(1975)
Ann Surg
, vol.182
, pp. 572-575
-
-
Breslow, A.1
-
26
-
-
0025894010
-
Human cutaneous malignant melanoma as a model for cancer
-
Clark WH Jr: Human cutaneous malignant melanoma as a model for cancer. Cancer Metastasis Rev 1991, 10:83-88
-
(1991)
Cancer Metastasis Rev
, vol.10
, pp. 83-88
-
-
Clark Jr., W.H.1
-
27
-
-
76949095094
-
Pirin delocalization in melanoma progression identified by high content immuno-detection based approaches
-
Licciulli S, Luise C, Zanardi A, Giorgetti L, Viale G, Lanfrancone L, Carbone R, Alcalay M: Pirin delocalization in melanoma progression identified by high content immuno-detection based approaches. BMC Cell Biol 2010, 11:5
-
(2010)
BMC Cell Biol
, vol.11
, pp. 5
-
-
Licciulli, S.1
Luise, C.2
Zanardi, A.3
Giorgetti, L.4
Viale, G.5
Lanfrancone, L.6
Carbone, R.7
Alcalay, M.8
-
28
-
-
0030835430
-
Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21(Cip1)
-
Woods D, Parry D, Cherwinski H, Bosch E, Lees E, McMahon M: Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1. Mol Cell Biol 1997, 17:5598-5611 (Pubitemid 27357656)
-
(1997)
Molecular and Cellular Biology
, vol.17
, Issue.9
, pp. 5598-5611
-
-
Woods, D.1
Parry, D.2
Cherwinski, H.3
Bosch, E.4
Lees, E.5
McMahon, M.6
-
29
-
-
66149138053
-
The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescence
-
Agger K, Cloos PA, Rudkjaer L, Williams K, Andersen G, Christensen J, Helin K: The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescence. Genes Dev 2009, 23:1171-1176
-
(2009)
Genes Dev
, vol.23
, pp. 1171-1176
-
-
Agger, K.1
Cloos, P.A.2
Rudkjaer, L.3
Williams, K.4
Andersen, G.5
Christensen, J.6
Helin, K.7
-
30
-
-
18544379476
-
Role of p21 in apoptosis and senescence of human colon cancer cells treated with camptothecin
-
DOI 10.1074/jbc.M112401200
-
Han Z, Wei W, Dunaway S, Darnowski JW, Calabresi P, Sedivy J, Hendrickson EA, Balan KV, Pantazis P, Wyche JH: Role of p21 in apoptosis and senescence of human colon cancer cells treated with camptothecin. J Biol Chem 2002, 277:17154-17160 (Pubitemid 34967748)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.19
, pp. 17154-17160
-
-
Han, Z.1
Wei, W.2
Dunaway, S.3
Darnowski, J.W.4
Calabresi, P.5
Sedivy, J.6
Hendrickson, E.A.7
Balan, K.V.8
Pantazis, P.9
Wyche, J.H.10
-
31
-
-
76749149998
-
Pirin downregulation is a feature of AML and leads to impairment of terminal myeloid differentiation
-
Licciulli S, Cambiaghi V, Scafetta G, Gruszka AM, Alcalay M: Pirin downregulation is a feature of AML and leads to impairment of terminal myeloid differentiation. Leukemia 2010, 24:429-437
-
(2010)
Leukemia
, vol.24
, pp. 429-437
-
-
Licciulli, S.1
Cambiaghi, V.2
Scafetta, G.3
Gruszka, A.M.4
Alcalay, M.5
|