Significantly longer envelope V2 loops are characteristic of heterosexually transmitted subtype B HIV-1 in trinidad

PLoS ONE

Volumn 6, Issue 6, 2011, Pages

  Collins Fairclough, Aneisha M ^a   Charurat, Manhattan ^b   Nadai, Yuka ^b   Pando, Maria ^c   Avila, Maria M ^c   Blattner, William A ^b   Carr, Jean K ^b  

^a UNIVERSITY OF TECHNOLOGY   (Jamaica)

^b UNIVERSITY OF MARYLAND   (United States)

^c UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; ASPARAGINE; THREONINE; VIRUS ENVELOPE PROTEIN;

AMINO ACID SUBSTITUTION; ARTICLE; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; GENE DELETION; GLYCOSYLATION; HETEROSEXUALITY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENY; SAMPLING; SEROCONVERSION; TRINIDAD AND TOBAGO; UNINDEXED SEQUENCE; VIRAL GENETICS; VIRUS ENVELOPE; VIRUS STRAIN; VIRUS TRANSMISSION; AMINO ACID SEQUENCE; CHEMISTRY; CLASSIFICATION; DISEASE TRANSMISSION; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; ISOLATION AND PURIFICATION; MOLECULAR GENETICS; RISK FACTOR; SEQUENCE HOMOLOGY; SEXUAL BEHAVIOR; SEXUALLY TRANSMITTED DISEASE; VIROLOGY;

HUMAN IMMUNODEFICIENCY VIRUS 1;

AMINO ACID SEQUENCE; COHORT STUDIES; HIV INFECTIONS; HIV-1; HUMANS; MOLECULAR SEQUENCE DATA; PHYLOGENY; RISK FACTORS; SEQUENCE HOMOLOGY, AMINO ACID; SEXUAL BEHAVIOR; SEXUALLY TRANSMITTED DISEASES, VIRAL; TRINIDAD AND TOBAGO; VIRAL ENVELOPE PROTEINS;

EID: 79959278557     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0019995     Document Type: Article

References (26)

1. Carr JK, (2006) Viral diversity as a challenge to HIV-1 vaccine development. Curr Opin HIV AIDS 1: 294-300.
2. Nadai Y, Eyzaguirre LM, Sill A, Cleghorn F, Nolte C, et al. (2009) HIV-1 epidemic in the Caribbean is dominated by subtype B. PLoS One 4: e4814.
3. Bartholomew C, Saxinger WC, Clark JW, Gail M, Dudgeon A, et al. (1987) Transmission of HTLV-I and HIV among homosexual men in Trinidad. JAMA 257: 2604-2608.
4. Cleghorn FR, Jack N, Carr JK, Edwards J, Mahabir B, et al. (2000) A distinctive clade B HIV type 1 is heterosexually transmitted in Trinidad and Tobago. Proc Natl Acad Sci U S A 97: 10532-10537.
5. Prabakaran P, Dimitrov AS, Fouts TR, Dimitrov DS, (2007) Structure and function of the HIV envelope glycoprotein as entry mediator, vaccine immunogen, and target for inhibitors. Adv Pharmacol 55: 33-97.
6. Rong R, Bibollet-Ruche F, Mulenga J, Allen S, Blackwell JL, et al. (2007) Role of V1V2 and other human immunodeficiency virus type 1 envelope domains in resistance to autologous neutralization during clade C infection. J Virol 81: 1350-1359.
7. Segura M, Sosa Estani S, Marone R, Bautista CT, Pando MA, et al. (2007) Buenos Aires cohort of men who have sex with men: prevalence, incidence, risk factors, and molecular genotyping of HIV type 1. AIDS Res Hum Retroviruses 23: 1322-1329.
8. Salazar-Gonzalez JF, Bailes E, Pham KT, Salazar MG, Guffey MB, et al. (2008) Deciphering human immunodeficiency virus type 1 transmission and early envelope diversification by single-genome amplification and sequencing. J Virol 82: 3952-3970.
9. Rose PP, Korber BT, (2000) Detecting hypermutations in viral sequences with an emphasis on G--> A hypermutation. Bioinformatics 16: 400-401.
10. Zhang M, Gaschen B, Blay W, Foley B, Haigwood N, et al. (2004) Tracking global patterns of N-linked glycosylation site variation in highly variable viral glycoproteins: HIV, SIV, and HCV envelopes and influenza hemagglutinin. Glycobiology 14: 1229-1246.
11. Jensen MA, Li FS, van 't Wout AB, Nickle DC, Shriner D, et al. (2003) Improved coreceptor usage prediction and genotypic monitoring of R5-to-X4 transition by motif analysis of human immunodeficiency virus type 1 env V3 loop sequences. J Virol 77: 13376-13388.
12. Gilbert MT, Rambaut A, Wlasiuk G, Spira TJ, Pitchenik AE, et al. (2007) The emergence of HIV/AIDS in the Americas and beyond. Proc Natl Acad Sci U S A 104: 18566-18570.
13. Hatada MK, Yoshimura K, Harada S, Kawanami Y, Shibata J, et al. (2009) HIV-1 evasion of a neutralizing anti-V3 antibody involves acquisition of a potential glycosylation site in V2. J Gen Virol.
14. Guo Q, Ho HT, Dicker I, Fan L, Zhou N, et al. (2003) Biochemical and genetic characterizations of a novel human immunodeficiency virus type 1 inhibitor that blocks gp120-CD4 interactions. J Virol 77: 10528-10536.
15. Keele BF, Giorgi EE, Salazar-Gonzalez JF, Decker JM, Pham KT, et al. (2008) Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection. Proc Natl Acad Sci U S A 105: 7552-7557.
16. Pando MA, Eyzaguirre LM, Segura M, Bautista CT, Marone R, et al. (2006) First report of an HIV-1 triple recombinant of subtypes B, C and F in Buenos Aires, Argentina. Retrovirology 3: 59.
17. Daniels RS, Kang C, Patel D, Xiang Z, Douglas NW, et al. (2003) An HIV type 1 subtype B founder effect in Korea: gp160 signature patterns infer circulation of CTL-escape strains at the population level. AIDS Res Hum Retroviruses 19: 631-641.
18. Bernardin F, Herring BL, Peddada L, Delwart EL, (2003) Primary infection of a male plasma donor with divergent HIV variants from the same source followed by rapid fluctuations in their relative frequency and viral recombination. AIDS Res Hum Retroviruses 19: 1009-1015.
19. Dacheux L, Moreau A, Ataman-Onal Y, Biron F, Verrier B, et al. (2004) Evolutionary dynamics of the glycan shield of the human immunodeficiency virus envelope during natural infection and implications for exposure of the 2G12 epitope. J Virol 78: 12625-12637.
20. Li M, Gao F, Mascola JR, Stamatatos L, Polonis VR, et al. (2005) Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodies. J Virol 79: 10108-10125.
21. Kothe DL, Decker JM, Li Y, Weng Z, Bibollet-Ruche F, et al. (2007) Antigenicity and immunogenicity of HIV-1 consensus subtype B envelope glycoproteins. Virology 360: 218-234.
22. Liu Y, Curlin ME, Diem K, Zhao H, Ghosh AK, et al. (2008) Env length and N-linked glycosylation following transmission of human immunodeficiency virus Type 1 subtype B viruses. Virology 374: 229-233.
23. Salazar-Gonzalez JF, Salazar MG, Keele BF, Learn GH, Giorgi EE, et al. (2009) Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection. J Exp Med 206: 1273-1289.
24. Liu Y, McNevin J, Cao J, Zhao H, Genowati I, et al. (2006) Selection on the human immunodeficiency virus type 1 proteome following primary infection. J Virol 80: 9519-9529.
25. Gottlieb GS, Heath L, Nickle DC, Wong KG, Leach SE, et al. (2008) HIV-1 variation before seroconversion in men who have sex with men: analysis of acute/early HIV infection in the multicenter AIDS cohort study. J Infect Dis 197: 1011-1015.
26. Gao F, Morrison SG, Robertson DL, Thornton CL, Craig S, et al. (1996) Molecular cloning and analysis of functional envelope genes from human immunodeficiency virus type 1 sequence subtypes A through G. The WHO and NIAID Networks for HIV Isolation and Characterization. J Virol 70: 1651-1667.