Magnetoencephalography as a putative biomarker for Alzheimer's disease

International Journal of Alzheimer's Disease

Volumn , Issue , 2011, Pages

  Zamrini, Edward ^a   Maestu, Fernando ^b   Pekkonen, Eero ^c   Funke, Michael ^a   Makela, Jyrki ^d   Riley, Myles ^a   Bajo, Ricardo ^b   Sudre, Gustavo ^e   Fernandez, Alberto ^b   Castellanos, Nazareth ^b   Del Pozo, Francisco ^b   Stam, C J ^f   Van Dijk, Bob W ^f   Bagic, Anto ^g   Becker, James T ^g,h  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b UNIVERSIDAD POLITÉCNICA DE MADRID   (Spain)

^c UNIVERSITY OF HELSINKI   (Finland)

^d HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^e CARNEGIE MELLON UNIVERSITY   (United States)

^f VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^g UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^h UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; NEUROTRANSMITTER;

ALZHEIMER DISEASE; CHOLINERGIC SYSTEM; DIAGNOSTIC ACCURACY; DISEASE MARKER; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; INTERMETHOD COMPARISON; LATENT PERIOD; MAGNETOENCEPHALOGRAPHY; MEMORY DISORDER; MILD COGNITIVE IMPAIRMENT; MISMATCH NEGATIVITY; NERVE DEGENERATION; NEUROANATOMY; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; PATHOLOGICAL ANATOMY; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PSEUDODEMENTIA; RELIABILITY; REVIEW; SLOW BRAIN WAVE;

EID: 79959261188     PISSN: None     EISSN: 20900252     Source Type: Journal    
DOI: 10.4061/2011/280289     Document Type: Review

References (103)

1. McKhann G., Drachman D., Folstein M., Katzman R., Price D. L., Stadlan E., Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease Neurology 1984 34 7 939 944 (Pubitemid 14076461)
2. APA, Diagnostic and Statistical Manual of Mental Disorders 1980 3rd New York, NY, USA APA
3. APA, Diagnostic and Statistical Manual on Mental Disorders-Revised (DSM-III-R) 1987 3rd Washington, DC, USA American Psychiatric Press
4. Petersen R. C., Smith G. E., Waring S. C., Ivnik R. J., Kokmen E., Tangelos E. G., Aging, memory, and mild cognitive impairment International Psychogeriatrics 1997 9 1 65 69 (Pubitemid 28045341)
5. Petersen R. C., Smith G. E., Waring S. C., Ivnik R. J., Tangalos E. G., Kokmen E., Mild cognitive impairment: clinical characterization and outcome Archives of Neurology 1999 56 3 303 308 (Pubitemid 29120227)
6. Petersen R. C., Doody R., Kurz A., Mohs R. C., Morris J. C., Rabins P. V., Ritchie K., Rossor M., Thal L., Winblad B., Current concepts in mild cognitive impairment Archives of Neurology 2001 58 12 1985 1992 (Pubitemid 33143977)
7. Petersen R., Mild Cognitive Impairment: Aging to Alzheimer's Disease 2003 New York, NY, USA Oxford University Press
8. Petersen R. C., Mild cognitive impairment as a diagnostic entity Journal of Internal Medicine 2004 256 3 183 194 (Pubitemid 39222988)
9. Petersen R. C., Roberts R. O., Knopman D. S., Boeve B. F., Geda Y. E., Ivnik R. J., Smith G. E., Jack C. R., Mild cognitive impairment: ten years later Archives of Neurology 2009 66 12 1447 1455
10. Morris J. C., Mild cognitive impairment is early-stage Alzheimer disease: time to revise diagnostic criteria Archives of Neurology 2006 63 1 15 16 (Pubitemid 43063856)
11. Morris J. C., Cummings J., Mild cognitive impairment (MCI) represents early-stage Alzheimer's disease Journal of Alzheimer's Disease 2005 7 3 235 239 (Pubitemid 40917253)
12. Morris J. C., Storandt M., Miller J. P., McKeel D. W., Price J. L., Rubin E. H., Berg L., Mild cognitive impairment represents early-stage Alzheimer disease Archives of Neurology 2001 58 3 397 405 (Pubitemid 32217456)
13. Morris J. C., McKeel D. W., Storandt M., Rubin E. H., Price J. L., Grant E. A., Ball M. J., Berg L., Very mild Alzheimer's disease: informant-based clinical, psychometric, and pathologic distinction from normal aging Neurology 1991 41 4 469 478
14. Khachaturian Z. S., Diagnosis of Alzheimer's disease Archives of Neurology 1985 42 11 1097 1105 (Pubitemid 16236926)
15. Gearing M., Mirra S. S., Hedreen J. C., Sumi S. M., Hansen L. A., Heyman A., The consortium to establish a registry for Alzheimer's disease (CERAD). Part X. Neuropathology confirmation of the clinical diagnosis of Alzheimer's disease Neurology 1995 45 3 461 466
16. Mirra S. S., Heyman A., McKeel D., Sumi S. M., Crain B. J., Brownlee L. M., Vogel F. S., Hughes J. P., Van Belle G., Berg L., The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease Neurology 1991 41 4 479 486
17. Dubois B., Feldman H. H., Jacova C., DeKosky S. T., Barberger-Gateau P., Cummings J., Delacourte A., Galasko D., Gauthier S., Jicha G., Meguro K., O'Brien J., Pasquier F., Robert P., Rossor M., Salloway S., Stern Y., Visser P. J., Scheltens P., Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS-ADRDA criteria Lancet Neurology 2007 6 8 734 746 (Pubitemid 47058377)
18. Schneider L. S., Organising the language of Alzheimer's disease in light of biomarkers The Lancet Neurology 2010 9 11 1044 1045
19. Aizenstein H. J., Nebes R. D., Saxton J. A., Price J. C., Mathis C. A., Tsopelas N. D., Ziolko S. K., James J. A., Snitz B. E., Houck P. R., Bi W., Cohen A. D., Lopresti B. J., DeKosky S. T., Halligan E. M., Klunk W. E., Frequent amyloid deposition without significant cognitive impairment among the elderly Archives of Neurology 2008 65 11 1509 1517
20. Wolk D. A., Price J. C., Saxton J. A., Snitz B. E., James J. A., Lopez O. L., Aizenstein H. J., Cohen A. D., Weissfeld L. A., Mathis C. A., Klunk W. E., DeKoskym S. T., Amyloid imaging in mild cognitive impairment subtypes Annals of Neurology 2009 65 5 557 568
21. Cirrito J. R., Yamada K. A., Finn M. B., Sloviter R. S., Bales K. R., May P. C., Schoepp D. D., Paul S. M., Mennerick S., Holtzman D. M., Synaptic activity regulates interstitial fluid amyloid- levels in vivo Neuron 2005 48 6 913 922 (Pubitemid 41814696)
22. Berger H., Uber das elektrenkephalogramm des menschen Archiv fur Psychiatrie 1931 98 1 16 60
23. Berger H., Uber das elektrenkephalogramm des menschen Archiv fur Psychiatrie 1932 98 1 231 254
24. Babiloni C., Binetti G., Cassetta E., Cerboneschi D., Dal Forno G., Del Percio C., Ferreri F., Ferri R., Lanuzza B., Miniussi C., Moretti D. V., Nobili F., Pascual-Marqui R. D., Rodriguez G., Romani G. L., Salinari S., Tecchio F., Vitali P., Zanetti O., Zappasodi F., Rossini P. M., Mapping distributed sources of cortical rhythms in mild Alzheimer's disease. A multicentric EEG study NeuroImage 2004 22 1 57 67 (Pubitemid 38515813)
25. Dierks T., Ihl R., Frolich L., Maurer K., Dementia of the Alzheimer type: effects on the spontaneous EEG described by dipole sources Psychiatry Research 1993 50 3 151 162 (Pubitemid 23289192)
26. Brenner R. P., Reynolds C. F., Ulrich R. F., Diagnostic efficacy of computerized spectral versus visual EEG analysis in elderly normal, demented and depressed subjects Electroencephalography and Clinical Neurophysiology 1988 69 2 110 117 (Pubitemid 18024751)
27. Jeong J., EEG dynamics in patients with Alzheimer's disease Clinical Neurophysiology 2004 115 7 1490 1505 (Pubitemid 38760295)
28. Smits L. L., Liedorp M., Koene T., Roos-Reuling I. E. W., Lemstra A. W., Scheltens P., Stam C. J., Van Der Flier W. M., EEG abnormalities are associated with different cognitive profiles in Alzheimer's disease Dementia and Geriatric Cognitive Disorders 2011 31 1 1 6
29. Grunwald M., Busse F., Hensel A., Riedel-Heller S., Kruggel F., Arendt T., Wolf H., Gertz H. J., Theta-power differences in patients with mild cognitive impairment under rest condition and during haptic tasks Alzheimer Disease and Associated Disorders 2002 16 1 40 48 (Pubitemid 34296621)
30. Jelic V., Johansson S. E., Almkvist O., Shigeta M., Julin P., Nordberg A., Winblad B., Wahlund L. O., Quantitative electroencephalography in mild cognitive impairment: longitudinal changes and possible prediction of Alzheimer's disease Neurobiology of Aging 2000 21 4 533 540 (Pubitemid 30621491)
31. Huang C., Wahlund L. O., Dierks T., Julin P., Winblad B., Jelic V., Discrimination of Alzheimer's disease and mild cognitive impairment by equivalent EEG sources: a cross-sectional and longitudinal study Clinical Neurophysiology 2000 111 11 1961 1967
32. Rodriguez G., Copello F., Vitali P., Perego G., Nobili F., EEG spectral profile to stage Alzheimer's disease Clinical Neurophysiology 1999 110 10 1831 1837 (Pubitemid 29459161)
33. Jelic V., Shigeta M., Jnlin P., Almkvist O., Winblad B., Wahhmd L. O., Quantitative electroencephalography power and coherence in Alzheimer's disease and mild cognitive impairment Dementia 1996 7 6 314 323 (Pubitemid 26341260)
34. Babiloni C., Ferri R., Binetti G., Vecchio F., Frisoni G. B., Lanuzza B., Miniussi C., Nobili F., Rodriguez G., Rundo F., Cassarino A., Infarinato F., Cassetta E., Salinari S., Eusebi F., Rossini P. M., Directionality of EEG synchronization in Alzheimer's disease subjects Neurobiology of Aging 2009 30 1 93 102
35. Nunez P. L., Silberstein R. B., Shi Z., Carpenter M. R., Srinivasan R., Tucker D. M., Doran S. M., Cadusch P. J., Wijesinghe R. S., EEG coherency II: experimental comparisons of multiple measures Clinical Neurophysiology 1999 110 3 469 486 (Pubitemid 29207498)
36. Nunez P. L., Srinivasan R., Westdorp A. F., Wijesinghe R. S., Tucker D. M., Silberstein R. B., Cadusch P. J., EEG coherency I: statistics, reference electrode, volume conduction, Laplacians, cortical imaging, and interpretation at multiple scales Electroencephalography and Clinical Neurophysiology 1997 103 5 499 515 (Pubitemid 27505343)
37. Moretti D. V., Frisoni G. B., Pievani M., Rosini S., Geroldi C., Binetti G., Rossini P. M., Cerebrovascular disease and hippocampal atrophy are differently linked to functional coupling of brain areas: an EEG coherence study in MCI subjects Journal of Alzheimer's Disease 2008 14 3 285 299 (Pubitemid 352040045)
38. Stam C. J., Van Dijk B. W., Synchronization likelihood: an unbiased measure of generalized synchronization in multivariate data sets Physica D 2002 163 3-4 236 251 (Pubitemid 34201314)
39. Stam C. J., Van Der Made Y., Pijnenburg Y. A. L., Scheltens PH., EEG synchronization in mild cognitive impairment and Alzheimer's disease Acta Neurologica Scandinavica 2003 108 2 90 96 (Pubitemid 36920656)
40. Pijnenburg Y. A. L., Vd Made Y., Van Cappellen Van Walsum A. M., Knol D. L., Scheltens PH., Stam C. J., EEG synchronization likelihood in mild cognitive impairment and Alzheimer's disease during a working memory task Clinical Neurophysiology 2004 115 6 1332 1339 (Pubitemid 38596717)
41. Rossini P. M., Del Percio C., Pasqualetti P., Cassetta E., Binetti G., Dal Forno G., Ferreri F., Frisoni G., Chiovenda P., Miniussi C., Parisi L., Tombini M., Vecchio F., Babiloni C., Conversion from mild cognitive impairment to Alzheimer's disease is predicted by sources and coherence of brain electroencephalography rhythms Neuroscience 2006 143 3 793 803 (Pubitemid 44781284)
42. Kramer M. A., Chang F. L., Cohen M. E., Hudson D., Szeri A. J., Synchronization measures of the scalp electroencephalogram can discriminate healthy from Alzheimer's subjects International Journal of Neural Systems 2007 17 2 61 69 (Pubitemid 46906231)
43. Dauwels J., Vialatte F., Musha T., Cichocki A., A comparative study of synchrony measures for the early diagnosis of Alzheimer's disease based on EEG NeuroImage 2010 49 1 668 693
44. Hof P. R., Bouras C., Constantinidis J., Morrison J. H., Selective disconnection of specific visual association pathways in cases of Alzheimer's disease presenting with Balint's syndrome Journal of Neuropathology and Experimental Neurology 1990 49 2 168 184 (Pubitemid 20111963)
45. Cohen D., Magnetoencephalography: detection of the brain's electrical activity with a superconducting magnetometer Science 1972 175 4022 664 666
46. George J. S., Aine C. J., Mosher J. C., Schmidt D. M., Ranken D. M., Schlitt H. A., Wood C. C., Lewine J. D., Sanders J. A., Belliveau J. W., Mapping function in the human brain with magnetoencephalography, anatomical magnetic resonance imaging, and functional magnetic resonance imaging Journal of Clinical Neurophysiology 1995 12 5 406 431
47. Manoach D. S., Halpern E. F., Kramer T. S., Chang Y., Goff D. C., Rauch S. L., Kennedy D. N., Gollub R. L., Test-retest reliability of a functional MRI working memory paradigm in normal and schizophrenic subjects American Journal of Psychiatry 2001 158 6 955 958 (Pubitemid 32547629)
48. Heaton R. K., Marcotte T. D., Rivera Mindt M., Sadek J., Moore D. J., Bentley H., Mccutchan J. A., Reicks C., Grant I., Atkinson J. H., Wallace M. R., Ellis R. J., Letendre S., Schrier R., Cherner M., Rippeth J., Woods S., Jernigan T., Hesselink J., Masliah E., Masys D. R., Frybarger M., Abramson I., Deutsch R., Wolfson T., The impact of HIV-associated neuropsychological impairment on everyday functioning Journal of the International Neuropsychological Society 2004 10 3 317 331 (Pubitemid 38779804)
49. Taulu S., Hari R., Removal of magnetoencephalographic artifacts with temporal signal-space separation: demonstration with single-trial auditory-evoked responses Human Brain Mapping 2009 30 5 1524 1534
50. Papanicolaou A. C., Simos P. G., Castillo E. M., Breier J. I., Sarkari S., Pataraia E., Billingsley R. L., Buchanan S., Wheless J., Maggio V., Maggio W. W., Magnetocephalography: a noninvasive alternative to the Wada procedure Journal of Neurosurgery 2004 100 5 867 876 (Pubitemid 38533971)
51. Stam C. J., Jones B. F., Manshanden I., van Cappellen van Walsum A. M., Montez T., Verbunt J. P. A., de Munck J. C., van Dijk B. W., Berendse H. W., Scheltens P., Magnetoencephalographic evaluation of resting-state functional connectivity in Alzheimer's disease NeuroImage 2006 32 3 1335 1344 (Pubitemid 44278696)
52. Raichle M. E., MacLeod A. M., Snyder A. Z., Powers W. J., Gusnard D. A., Shulman G. L., A default mode of brain function Proceedings of the National Academy of Sciences of the United States of America 2001 98 2 676 682 (Pubitemid 32105102)
53. Bai F., Zhang Z., Yu H., Shi Y., Yuan Y., Zhu W., Zhang X., Qian Y., Default-mode network activity distinguishes amnestic type mild cognitive impairment from healthy aging: a combined structural and resting-state functional MRI study Neuroscience Letters 2008 438 1 111 115
54. Buckner R. L., Snyder A. Z., Shannon B. J., LaRossa G., Sachs R., Fotenos A. F., Sheline Y. I., Klunk W. E., Mathis C. A., Morris J. C., Mintun M. A., Molecular, structural, and functional characterization of Alzheimer's disease: evidence for a relationship between default activity, amyloid, and memory Journal of Neuroscience 2005 25 34 7709 7717 (Pubitemid 41208641)
55. Fernndez A., Hornero R., Mayo A., Poza J., Maestu F., Ortiz Alonso T., Quantitative magnetoencephalography of spontaneous brain activity in alzheimer disease: an exhaustive frequency analysis Alzheimer Disease and Associated Disorders 2006 20 3 153 159 (Pubitemid 44259789)
56. Fernndez A., Turrero A., Zuluaga P., Gil P., Maestu F., Campo P., Ortiz T., Magnetoencephalographic parietal dipole density in mild cognitive impairment: preliminary results of a method to estimate the risk of developing Alzheimer disease Archives of Neurology 2006 63 3 427 430
57. Fernndez A., Garca-Segura J. M., Ortiz T., Montoya J., Maestu F., Gil-Gregorio P., Campo P., Viao J., Proton magnetic resonance spectroscopy and magnetoencephalographic estimation of delta dipole density: a combination of techniques that may contribute to the diagnosis of Alzheimer's disease Dementia and Geriatric Cognitive Disorders 2005 20 2-3 169 177 (Pubitemid 41191634)
58. Osipova D., Pekkonen E., Ahveninen J., Enhanced magnetic auditory steady-state response in early Alzheimer's disease Clinical Neurophysiology 2006 117 9 1990 1995 (Pubitemid 44247894)
59. Hillebrand A., Barnes G. R., A quantitative assessment of the sensitivity of whole-head MEG to activity in the adult human cortex NeuroImage 2002 16 3, part 1 638 650 (Pubitemid 34852428)
60. Stam C. J., Van Cappellen van Walsum A. M., Pijnenburg Y. A. L., Berendse H. W., De Munck J. C., Scheltens P., Van Dijk B. W., Generalized synchronization of MEG recordings in Alzheimer's disease: evidence for involvement of the gamma band Journal of Clinical Neurophysiology 2002 19 6 562 574 (Pubitemid 36008381)
61. Stam C. J., Jones B. F., Manshanden I., van Cappellen van Walsum A. M., Montez T., Verbunt J. P. A., de Munck J. C., van Dijk B. W., Berendse H. W., Scheltens P., Magnetoencephalographic evaluation of resting-state functional connectivity in Alzheimer's disease NeuroImage 2006 32 3 1335 1344 (Pubitemid 44278696)
62. Fernndez A., Maestu F., Amo C., Gil P., Fehr T., Wienbruch C., Rockstroh B., Elbert T., Ortiz T., Focal temporoparietal slow activity in Alzheimer's disease revealed by magnetoencephalography Biological Psychiatry 2002 52 7 764 770
63. Osipova D., Rantanen K., Ahveninen J., Source estimation of spontaneous MEG oscillations in mild cognitive impairment Neuroscience Letters 2006 405 1-2 57 61 (Pubitemid 44142825)
64. Fernndez A., Arrazola J., Maestu F., Arno C., Gil-Gregorio P., Wienbruch C., Ortiz T., Correlations of hippocampal atrophy and focal low-frequency magnetic activity in Alzheimer disease: volumetric MR imagingmagnetoencephalographic study American Journal of Neuroradiology 2003 24 3 481 487 (Pubitemid 36359003)
65. Maestu F., Arrazola J., Fernndez A., Simos P. G., Amo C., Gil-Gregorio P., Fernandez S., Papanicolaou A., Ortiz T., Do cognitive patterns of brain magnetic activity correlate with hippocampal atrophy in Alzheimer's disease? Journal of Neurology Neurosurgery and Psychiatry 2003 74 2 208 212 (Pubitemid 36160682)
66. Maestu F., Fernandez A., Simos P. G., Lpez-Ibor M. I., Campo P., Criado J., Rodriguez-Palancas A., Ferre F., Amo C., Ortiz T., Profiles of brain magnetic activity during a memory task in patients with Alzheimer's disease and in non-demented elderly subjects, with or without depression Journal of Neurology, Neurosurgery and Psychiatry 2004 75 8 1160 1162 (Pubitemid 39005775)
67. Fernndez A., Rodriguez-Palancas A., Lpez-Ibor M., Increased occipital delta dipole density in major depressive disorder determined by magnetoencephalography Journal of Psychiatry and Neuroscience 2005 30 1 17 23 (Pubitemid 40289242)
68. Maestu F., Campo P., Gil-Gregorio P., Fernndez S., Fernndez A., Ortiz T., Medial temporal lobe neuromagnetic hypoactivation and risk for developing cognitive decline in elderly population: a 2-year follow-up study Neurobiology of Aging 2006 27 1 32 37 (Pubitemid 41627947)
69. Friston K. J., Frith C. D., Liddle P. F., Frackowiak R. S. J., Functional connectivity: the principal-component analysis of large (PET) data sets Journal of Cerebral Blood Flow and Metabolism 1993 13 1 5 14 (Pubitemid 23016598)
70. Friston K. J., Functional and effective connectivity in neuroimaging: a synthesis Human Brain Mapping 1994 2 1-2 56 78 (Pubitemid 124000442)
71. Buechel C., Friston K. J., Frackowiak R. S. J., Friston K. J., Frith C. D., Dolan R. J., Mazziotta J. C., Characterising functional integration Human Brain Function 1997 San Diego, Calif, USA Scademic Press 127 140
72. McIntosh A. R., Grady C. L., Ungerleider L. G., Haxby J. V., Rapoport S. I., Horwitz B., Network analysis of cortical visual pathways mapped with PET Journal of Neuroscience 1994 14 2 655 666 (Pubitemid 24043922)
73. Herbster A. N., Nichols T., Wiseman M. B., Mintun M. A., Dekosky S. T., Becker J. T., Functional connectivity in auditoryverbal short-term memory in Alzheimer's disease NeuroImage 1996 4 2 67 77 (Pubitemid 26337399)
74. Morrison J. H., Rogers J., Scherr S., Benoit R., Bloom F. E., Somatostatin immunoreactivity in neuritic plaques of Alzheimer's patients Nature 1985 314 6006 90 92 (Pubitemid 15142024)
75. Varela F., Lachaux J. P., Rodriguez E., Martinerie J., The brainweb: phase synchronization and large-scale integration Nature Reviews Neuroscience 2001 2 4 229 239 (Pubitemid 33673064)
76. Fries P., A mechanism for cognitive dynamics: neuronal communication through neuronal coherence Trends in Cognitive Sciences 2005 9 10 474 480 (Pubitemid 41338822)
77. Engel A. K., Fries P., Singer W., Dynamic predictions: oscillations and synchrony in top-down processing Nature Reviews Neuroscience 2001 2 10 704 716 (Pubitemid 33674816)
78. Palva J. M., Monto S., Kulashekhar S., Palva S., Neuronal synchrony reveals working memory networks and predicts individual memory capacity Proceedings of the National Academy of Sciences of the United States of America 2010 107 16 7580 7585
79. Palva S., Monto S., Palva J. M., Graph properties of synchronized cortical networks during visual working memory maintenance NeuroImage 2010 49 4 3257 3268
80. Dai W., Lopez O. L., Carmichael O. T., Becker J. T., Kuller L. H., Gach H. M., Abnormal regional cerebral blood flow in cognitively normal elderly subjects with hypertension Stroke 2008 39 2 349 354 (Pubitemid 351619454)
81. Dai W., Lopez O. L., Carmichael O. T., Becker J. T., Kuller L. H., Gach H. M., Mild cognitive impairment and alzheimer disease: patterns of altered cerebral blood flow at MR imaging Radiology 2009 250 3 856 866
82. Stam C. J., Use of magnetoencephalography (MEG) to study functional brain networks in neurodegenerative disorders Journal of the Neurological Sciences 2010 289 1-2 128 134
83. Bajo R., Maest F., Nevado A., Sancho M., Gutirrez R., Campo P., Castellanos N. P., Gil P., Moratti S., Pereda E., Del-Pozo F., Functional connectivity in mild cognitive impairment during a memory task: implications for the disconnection hypothesis Journal of Alzheimer's Disease 2010 22 1 183 193
84. Maestu F., Baykova E., Ruiz J. M., Montejo P., Montenegro M., Llanero M., Solesio E., Gil P., Yubero R., Paul N., Pozo F., Nevado A., Increased biomagnetic activity in healthy elderly with subjective memory complaints Clinical Neurophysiology 2011 122 3 499 505
85. Hernandez I., Martinez-Lage P., Alegret M., Subjective memory complaints are associated with impending cognitive decline Neurology 2010 74 supplement 2 A21
86. Perry E. K., The cholinergic system in old age and Alzheimer's disease Age and Ageing 1980 9 1 1 8 (Pubitemid 10215539)
87. Whitehouse P. J., Price D. L., Clark A. W., Alzheimer disease: evidence for selective loss of cholinergic neurons in the nucleus basalis Annals of Neurology 1981 10 2 122 126 (Pubitemid 11053099)
88. Karas G. B., Scheltens P., Rombouts S. A. R. B., Visser P. J., Van Schijndel R. A., Fox N. C., Barkhof F., Global and local gray matter loss in mild cognitive impairment and Alzheimer's disease NeuroImage 2004 23 2 708 716 (Pubitemid 39370621)
89. Chtelat G., Desgranges B., De la Sayette V., Viader F., Eustache F., Baron J. C., Mapping gray matter loss with voxel-based morphometry in mild cognitive impairment NeuroReport 2002 13 15 1939 1943 (Pubitemid 35398965)
90. Teipel S. J., Flatz W. H., Heinsen H., Bokde A. L. W., Schoenberg S. O., Stckel S., Dietrich O., Reiser M. F., Mller H. J., Hampel H., Measurement of basal forebrain atrophy in Alzheimer's disease using MRI Brain 2005 128 11 2626 2644 (Pubitemid 41552947)
91. Baron J. C., Chtelat G., Desgranges B., Perchey G., Landeau B., De La Sayette V., Eustache F., In vivo mapping of gray matter loss with voxel-based morphometry in mild Alzheimer's disease NeuroImage 2001 14 2 298 309 (Pubitemid 32709545)
92. Grothe M., Zaborszky L., Atienza M., Gil-Neciga E., Rodriguez-Romero R., Teipel S. J., Amunts K., Suarez-Gonzalez A., Cantero J. L., Reduction of basal forebrain cholinergic system parallels cognitive impairment in patients at high risk of developing alzheimer's disease Cerebral Cortex 2010 20 7 1685 1695
93. Hall A. M., Moore R. Y., Lopez O. L., Kuller L., Becker J. T., Basal forebrain atrophy is a presymptomatic marker for Alzheimer's disease Alzheimer's and Dementia 2008 4 4 271 279 (Pubitemid 351866120)
94. Tariot P. N., Patel S. V., Cox C., Henderson R. E., Age-related decline in central cholinergic function demonstrated with scopolamine Psychopharmacology 1996 125 1 50 56 (Pubitemid 26155364)
95. Pekkonen E., Jaaskelainen I. P., Hietanen M., Huotilainen M., Naatanen R., Ilmoniemi R. J., Erkinjuntti T., Impaired preconscious auditory processing and cognitive functions in Alzheimer's disease Clinical Neurophysiology 1999 110 11 1942 1947 (Pubitemid 29454622)
96. Osipova D., Ahveninen J., Kaakkola S., Jaaskelainen I. P., Huttunen J., Pekkonen E., Effects of scopolamine on MEG spectral power and coherence in elderly subjects Clinical Neurophysiology 2003 114 10 1902 1907 (Pubitemid 38366116)
97. Pekkonen E., Jaaskelainen I. P., Kaakkola S., Ahveninen J., Cholinergic modulation of preattentive auditory processing in aging NeuroImage 2005 27 2 387 392 (Pubitemid 41074840)
98. Lee D., Sawrie S. M., Simos P. G., Killen J., Knowlton R. C., Reliability of language mapping with magnetic source imaging in epilepsy surgery candidates Epilepsy and Behavior 2006 8 4 742 749
99. Missonnier P., Gold G., Fazio-Costa L., Early event-related potential changes during working memory activation predictrapid decline in mild cognitive impairment The Journals of Gerontology 2006 60A 5 660 666
100. Liljestrm M., Kujala J., Jensen O., Salmelin R., Neuromagnetic localization of rhythmic activity in the human brain: a comparison of three methods NeuroImage 2005 25 3 734 745 (Pubitemid 40461713)
101. Yoo S. S., Wei X., Dickey C. C., Guttmann C. R. G., Panych L. P., Long-term reproducibility analysis of fMRI using hand motor task International Journal of Neuroscience 2005 115 1 55 77 (Pubitemid 40065759)
102. Pekkonen E., Mismatch negativity in aging and in Alzheimer's and Parkinson's disease Audiology and Neuro-Otology 2000 5 3-4 216 224 (Pubitemid 30312190)
103. Mitchell T. M., Hutchinson R., Niculescu R. S., Pereira F., Wang X., Just M., Newman S., Learning to decode cognitive states from brain images Machine Learning 2004 57 1-2 145 175