Mild cognitive impairment (MCI) represents early-stage Alzheimer's disease

Journal of Alzheimer's Disease

Volumn 7, Issue 3, 2005, Pages 235-239

  Morris, John C ^a   Cummings, Jeffrey ^b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; DONEPEZIL;

AGING; ALZHEIMER DISEASE; CLINICAL FEATURE; CLINICAL TRIAL; COGNITIVE DEFECT; CONFERENCE PAPER; DEMENTIA; DIAGNOSTIC ACCURACY; DISEASE COURSE; DISEASE SEVERITY; HUMAN; MEMORY DISORDER; NEUROPSYCHOLOGICAL TEST; PREVALENCE; PRIORITY JOURNAL; SCORING SYSTEM;

EID: 21444458336     PISSN: 13872877     EISSN: None     Source Type: Journal    
DOI: 10.3233/JAD-2005-7306     Document Type: Conference Paper

References (41)

1. AGS Clinical Practice Committee, Guidelines abstracted from the American Academy of Neurology's Dementia Guidelines for early detection, diagnosis, and management of dementia [Special Article], J Am Geriatr Soc 51 (2003), 869-973.
2. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 4 ed., Washington, D.C.: American Psychiatric Association, 1994.
3. L. Berg, D.W. McKeel, Jr., J.P. Miller, M. Storandt, E.H. Rubin, J.C. Morris, J. Baty, M. Coats, J. Norton, A.M. Goate, J.L. Price, M. Gearing, S.S. Mirra and A.M. Saunders, Clinico-pathologic studies in cognitively healthy aging and Alzheimer disease: Relation of histologic markers to dementia severity, age, sex, and apolipoprotein E genotype, Arch Neurol 55 (1998), 326-335.
4. P.Z. Cacchione, K.K. Powlishta, E.A. Grant, V.D. Buckles and J.C. Morris, Accuracy of collateral source reports in very mild to mild dementia of the Alzheimer type, J Am Geriatr Soc 51 (2003), 819-823.
5. D.B. Carr, S. Gray, J. Baty and J.C. Morris, The value of informant vs. individual's complaints of memory impairment in early dementia, Neurology 55 (2000), 1724-1726.
6. S.T. DeKosky, M.D. Ikonomovic, S.D. Styren, L. Beckett, S. Wisniewski, D.A. Bennett, E.J. Cochran, J.H. Kordower and E.J. Mufson, Upregulation of choline acetyltransferase activity in hippocampus and frontal cortex of elderly subjects with mild cognitive impairment, Ann Neurol 51 (2002), 145-155.
7. M.G. Dik, C. Jonker, L.M. Bouter, M.I. Geerlings, G.J. van Kamp and D.J.H. Deeg, APOE-e4 is associated with memory decline in cognitively impaired elderly, Neurology 54 (2000), 1492-1497.
8. S.J. Duff Canning, L. Leach, D. Stuss, L. Ngo and S.E. Black, Diagnostic utility of abbreviated fluency measures in Alzheimer disease and vascular dementia, Neurology 62 (2004), 556-562.
9. E.R. Edwards, K. Lingquist and K. Yaffe, Clinical profile and course of cognitively normal patients evaluated in memory disorders clinics. Neurology 62 (2004), 1639-1642.
10. M.R. Farlow, Y. He, S. Tekin, J. Xu, R. Lane and H.C. Charles, Impact of APOE in mild cognitive impairment, Neurology 63 (2004), 1898-1901.
11. H. Feldman, P. Scheltens, E. Scarpini, N. Hermann, P. Mesenbrink, L. Mancione, S. Tekin, R. Lane and S. Ferris, Behavioral symptoms in mild cognitive impairment, Neurology 62 (2004), 1199-1201.
12. J.D. Fisk, H.R. Merry and K. Rockwood, Variations in case definition affect prevalence but not outcomes of mild cognitive impairment, Neurology 61 (2003), 1179-1184.
13. M.F. Folstein, S.E. Folstein and P.R. McHugh, Mini-mental State: A practical method for grading the cognitive state of patients for the clinicians, J Psychiatr Res 12 (1975), 189-198.
14. M. Ganguli, H.H. Dodge, C. Shen and S.T. DeKosky, Mild cognitive impairment, amnestic type; An epidemiologic study, Neurology 63 (2004), 115-121.
15. M. Ganguli, E. Rodriguez, B. Mulsant, S. Richards, R. Pandav, J. Vander Bilt, H.H. Dodge, G.P. Stoehr, J. Saxton, R.K. Morycz, R.T. Rubin, B. Farkas and S.T. DeKosky, Detection and management of cognitive impairment in primary care: the Steel Valley Seniors Survey, J Am Geriatr Soc 52 (2004), 1668-1675.
16. A.K. Godbolt, L. Cipolotti, H. Watt, N.C. Fox, J.C. Janssen and M.N. Rossor, The natural history of Alzheimer disease: A longitudinal presymptomatic and symptomatic study of a familial cohort, Arch Neurol 61 (2004), 1743-1748.
17. J.E. Graham, K. Rockwood, L.B. Beattie, R. Eastwood, S. Gauthier, H. Tuokko and I. McDowell, Prevalence and severity of cognitive impairment with and without dementia in an elderly population, Lancet 349 (1997), 1793-1796.
18. H.R. Griffith, K. Belue, A. Sicola, S. Krzywanski, E. Zamrini, L. Harrell and D.C. Marson, Impaired financial abilities in mild cognitive impairment, Neurology 60 (2003), 449-457.
19. M. Grundman, R.C. Petersen, S.H. Ferris, R.G. Thomas, P.S. Aisen, D.A. Bennett, N.L. Foster, C.R. Jack, D.R. Galasko, R. Doody, J. Kaye, M. Sano, R. Mohs, S. Gauthier, H.T. Kim, S. Jin, A.N. Schultz, K. Schafer, R. Mulnard, C.H. van Dyck, J. Mintzer, E.Y. Zamrini, D. Cahn-Weiner and L.J. Thal, for the Alzheimer's Disease Cooperative Study. Mild cognitive impairment can be distinguished from Alzheimer disease and normal aging for clinical trials, Arch Neurol 61 (2004), 59-66.
20. C.R. Jack, M.M. Shiung, J.L. Gunter, P.C. O'Brien, S.D. Weigand, D.S. Knopman, B.F. Boeve, R.J. Ivnik, G.E. Smith, R.H. Cha, E.G. Tangalos and R.C. Petersen, Comparison of different MRI brain atrophy rate measures with clinical disease progression in AD, Neurology 62 (2004), 591-600.
21. Y-P. Jin, M. Gatz, B. Johansson and N.L. Pedersen, Sensitivity and specificity of dementia coding in two Swedish disease registries. Neurology 63 (2004), 739-741.
22. A.F. Jorm, The value of informant reports for assessment and prediction of dementia [Editorial], J Am Geriatr Soc 51 (2003), 881-882.
23. D.S. Knopman, S.T. DeKosky, J.L. Cummings, H. Chui, J. Corey-Bloom, N. Relkin, G.W. Small, B. Miller and J.C. Stevens, Practice parameter: Diagnosis of dementia (an evidence-based review) Report of the Quality Standards Subcommittee of the American Academy of Neurology, Neurology 56 (2001), 1143-1153.
24. J.H. Kordower, Y. Chu, G.T. Stebbins, S.T. DeKosky, E.J. Cochran, D. Bennett and E.J. Mufson, Loss and atrophy of layer II entorhinal cortex neurons in elderly people with mild cognitive impairment, Ann Neurol 49 (2001), 202-213.
25. E.S.C. Korf, L-O. Wahlund, P.J. Visser and P. Scheltens, Medial temporal lobe atrophy on MRI predicts dementia in patients with mild cognitive impairment, Neurology 63 (2004), 94-100.
26. R. Levy, Aging-associated cognitive decline, Int Psychogeriatr 6 (1994), 63-68.
27. R. Lindeboom, B. Schmand, R. Holman, R.J. deHaan and M. Vermeulen, Improved brief assessment of cognition in aging and dementia, Neurology 63 (2004), 543-546.
28. P.J. Modrego and J. Ferrandez, Depression in patients with mild cognitive impairment increases the risk of developing dementia of Alzheimer type: a prospective cohort study, Arch Neurol 61 (2004), 1290-1293.
29. J.C. Morris, D.W. McKeel Jr., M. Storandt, E.H. Rubin, J.L. Price, E.A. Grant, M.J. Ball and L. Berg, Very mild Alzheimer's disease: Informant-based clinical, psychometric, and pathologic distinction from normal aging, Neurology 41 (1991), 469-478.
30. J.C. Morris, M. Storandt, J.P. Miller, D.W. McKeel Jr., J.L. Price, E.H. Rubin and L. Berg, Mild cognitive impairment represents early-stage Alzheimer's disease, Arch Neurol 58 (2001), 397-405.
31. L. Mosconi, D. Perani, S. Sorbi, K. Herholz, B. Nacmias, V Holthoff, E. Salmon, J-C. Baron, M.T.R. DeCristofaro, A. Padovani, B. Borroni, M. Franceschi, L. Bracco and A. Pupi, MCI conversion to dementia and the APOE genotype; a prediction study with FDG-PET, Neurology 63 (2004), 2332-2340.
32. R. Petersen, M. Grundman, R. Thomas and L. Thai, Donepezil and vitamin E as treatments for mild cognitive impairment, Neurobiol Aging 25(S2) (2004), 20, Abstract.
33. R.C. Petersen, Mild cognitive impairment as a diagnostic entity, J Intern Med 256 (2004), 183-194.
34. R.C. Petersen, J.C. Stevens, M. Ganguli, E.G. Tangalos, J.L. Cummings and S.T. DeKosky, Practice parameter: Early detection of dementia: Mild cognitive impairment (an evidence-based review). Report of the Quality Standards Subcommittee of the American Academy of Neurology, Neurology 56 (2001), 1133-1142.
35. D. Pratico, C.M. Clark, F. Liun, V.Y.M. Lee and J.Q. Trojanowski, Increase of brain oxidative stress in mild cognitive impairment: A possible predictor of Alzheimer disease, Arch Neurol 59 (2002), 972-976.
36. S. Salloway, S. Ferris, A. Kluger, R. Goldman, T. Griesing, D. Kumar and S. Richardson, for the Donepezil 401 Study Group. Efficacy of donepezil in mild cognitive impairment; A randomized placebo-controlled trial, Neurology 63 (2004), 651-657.
37. B. Seltzer, P. Zolnouni, M. Nunez, R. Goldman, D. Kumar, J. Ieni and S. Richardson, for the Donepezil 402 Study Group. Efficacy of donepezil in early-stage Alzheimer disease, Arch Neurol 61 (2004), 1852-1856.
38. M. Storandt, E.A. Grant, J.P. Miller and J.C. Morris, Rates of progression in mild cognitive impairment and early Alzheimer's disease, Neurology 59 (2002), 1034-1041.
39. M.C. Tierney, N. Herrmann, D.M. Geslani and J.P. Szalai, Contribution of informant and patient ratings to the accuracy of the Mini-Mental State Examination in predicting probable Alzheimer's disease, J Am Geriatr Soc 51 (2003), 813-818.
40. B. Winblad, K. Palmer, M. Kivipelto, V. Jelic, L. Fratiglioni, L-O. Wahlund, A. Nordberg, L. Backman, M. Albert, O. Almkvist, H. Arai, H. Basun, K. Blennow, M. DeLeon, C. DeCarli, T. Erkinjuntti, E. Giacobini, C. Graff, J. Hardy, C. Jack, A. Jorm, K. Ritchie, C. van Duijn, P. Visser and R.C. Petersen, Mild cognitive impairment-beyond controversies, towards a consensus: Report of the International Working Group on mild cognitive impairment, J Intern Med 256 (2004), 240-246.
41. Y. Yang, E.J. Mufson and K. Herrup, Neuronal cell death is preceded by cell cycle events at all stages of Alzheimer's disease, J Neurol Sci 23 (2003), 2557.