Systemically administered ligands of toll-like receptor 2, -4, and -9 induce distinct inflammatory responses in the murine lung

Mediators of Inflammation

Volumn 2011, Issue , 2011, Pages

  Boehm, O ^a   Ehrentraut, H ^a   Meyer, R ^b   Schwederski, M ^a   Ehrentraut, S ^a   Velten, M ^a   Grohe C ^c   Knuefermann, P ^a   Baumgarten, G ^a  

^a UNIVERSITY HOSPITAL BONN   (Germany)

^b UNIVERSITY OF BONN   (Germany)

^c Department for Pneumology Evangelische Lungenklinik ^*  (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CPG OLIGODEOXYNUCLEOTIDE; CXCL3 CHEMOKINE; EOTAXIN; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GELATINASE A; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 12P35; INTERLEUKIN 12P40; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; LIGAND; LIPOTEICHOIC ACID; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MESSENGER RNA; MYELOPEROXIDASE; NEUTROPHIL COLLAGENASE; STROMELYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; MATRIX METALLOPROTEINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; C57BL 6 MOUSE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INDUCTION; GENE EXPRESSION REGULATION; IMMUNE RESPONSE; MALE; MOUSE; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; UPREGULATION; ZYMOGRAPHY; ANIMAL; C57BL MOUSE; GENETICS; HUMAN; IMMUNOLOGY; INFLAMMATION; LUNG; METABOLISM; PHYSIOLOGY;

MURINAE; MUS;

ANIMALS; CYTOKINES; HUMANS; INFLAMMATION; LIGANDS; LUNG; MALE; MATRIX METALLOPROTEINASES; MICE; MICE, INBRED C57BL; TISSUE INHIBITOR OF METALLOPROTEINASES; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR-ALPHA;

EID: 79959243339     PISSN: 09629351     EISSN: 14661861     Source Type: Journal    
DOI: 10.1155/2011/746532     Document Type: Article

References (40)

1. Angus D. C., Pereira C. A. P., Silva E., Epidemiology of severe sepsis around the world Endocrine, Metabolic and Immune Disorders 2006 6 2 207 212 (Pubitemid 43881034)
2. Kuwano K., Epithelial cell apoptosis and lung remodeling Cellular Molecular Immunology 2007 4 6 419 429
3. Wheeler A. P., Bernard G. R., Treating patients with severe sepsis The New England Journal of Medicine 1999 340 3 207 214 (Pubitemid 29063218)
4. Rubenfeld G. D., Herridge M. S., Epidemiology and outcomes of acute lung injury Chest 2007 131 2 554 562 (Pubitemid 46280419)
5. Poltorak A., He X., Smirnova I., Liu MU. Y., Van Huffel C., Du X., Birdwell D., Alejos E., Silva M., Galanos C., Freudenberg M., Ricciardi-Castagnoli P., Layton B., Beutler B., Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in TLR4 gene Science 1998 282 5396 2085 2088 (Pubitemid 29001265)
6. Takeuchi O., Hoshino K., Kawai T., Sanjo H., Takada H., Ogawa T., Takeda K., Akira S., Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components Immunity 1999 11 4 443 451 (Pubitemid 29504199)
7. Hemmi H., Takeuchi O., Kawai T., Kaisho T., Sato S., Sanjo H., Matsumoto M., Hoshino K., Wagner H., Takeda K., Akira S., A Toll-like receptor recognizes bacterial DNA Nature 2000 408 6813 740 745 (Pubitemid 32015992)
8. Krieg A. M., Yi A. K., Matson S., Waldschmidt T. J., Bishop G. A., Teasdale R., Koretzky G. A., Klinman D. M., CpG motifs in bacterial DNA trigger direct B-cell activation Nature 1995 374 6522 546 549
9. Nishimura M., Naito S., Tissue-specific mRNA expression profiles of human toll-like receptors and related genes Biological and Pharmaceutical Bulletin 2005 28 5 886 892 (Pubitemid 40740661)
10. Schrder N. W. J., Arditi M., IEIIS Meeting minireview: the role of innate immunity in the pathogenesis of asthma: evidence for the involvement of Toll-like receptor signaling Journal of Endotoxin Research 2007 13 5 305 312 (Pubitemid 350056226)
11. Pawar R. D., Ramanjaneyulu A., Kulkarni O. P., Lech M., Segerer S., Anders H. J., Inhibition of Toll-like receptor-7 (TLR-7) or TLR-7 plus TLR-9 attenuates glomerulonephritis and lung injury in experimental lupus Journal of the American Society of Nephrology 2007 18 6 1721 1731 (Pubitemid 46870309)
12. Baumgarten G., Knuefermann P., Wrigge H., Putensen C., Stapel H., Fink K., Meyer R., Hoeft A., Groh C., Role of toll-like receptor 4 for the pathogenesis of acute lung injury in gram-negative sepsis European Journal of Anaesthesiology 2006 23 12 1041 1048 (Pubitemid 44622933)
13. Li J., Ma Z., Tang Z. L., Stevens T., Pitt B., Li S., CpG DNA-mediated immune response in pulmonary endothelial cells American Journal of Physiology 2004 287 3 L552 L558
14. Knuefermann P., Baumgarten G., Koch A., Schwederski M., Velten M., Ehrentraut H., Mersmann J., Meyer R., Hoeft A., Zacharowski K., Groh C., CpG oligonucleotide activates Toll-like receptor 9 and causes lung inflammation in vivo Respiratory Research 2007 8, article 72
15. Ishii K. J., Uematsu S., Akira S., 'Toll' gates for future immunotherapy Current Pharmaceutical Design 2006 12 32 4135 4142
16. Hoogerwerf J. J., De Vos A. F., Bresser P., Van Der Zee J. S., Pater J. M., De Boer A., Tanck M., Lundell D. L., Her-Jenh C., Draing C., Von Aulock S., Van Der Poll T., Lung inflammation induced by lipoteichoic acid or lipopolysaccharide in humans American Journal of Respiratory and Critical Care Medicine 2008 178 1 34 41 (Pubitemid 351919191)
17. Morath S., Geyer A., Hartung T., Structure-function relationship of cytokine induction by lipoteichoic acid from Staphylococcus aureus Journal of Experimental Medicine 2001 193 3 393 397 (Pubitemid 32524522)
18. Baumgarten G., Knuefermann P., Schuhmacher G., Vervlgyi V., Von Rappard J., Dreiner U., Fink K., Djoufack C., Hoeft A., Groh C., Knowlton A. A., Meyer R., Toll-like receptor 4, nitric oxide, and myocardial depression in endotoxemia Shock 2006 25 1 43 49
19. Knuefermann P., Schwederski M., Velten M., Krings P., Ehrentraut H., Rdiger M., Boehm O., Fink K., Dreiner U., Groh C., Hoeft A., Baumgarten G., Koch A., Zacharowski K., Meyer R., Bacterial DNA induces myocardial inflammation and reduces cardiomyocyte contractility: role of Toll-like receptor 9 Cardiovascular Research 2008 78 1 26 35 (Pubitemid 351430962)
20. Alves-Filho J. C., Freitas A., Souto F. O., Spiller F., Paula-Neto H., Silva J. S., Gazzinelli R. T., Teixeira M. M., Ferreira S. H., Cunha F. Q., Regulation of chemokine receptor by Toll-like receptor 2 is critical to neutrophil migration and resistance to polymicrobial sepsis Proceedings of the National Academy of Sciences of the United States of America 2009 106 10 4018 4023
21. Coligan J., Kruisbeek A. M., Margulies D. H., Shevach E. M., Strober W., Coico R., Measurement of tumor necrosis factor Current Protocols in Immunology 1994 New York, NY, USA John Wiley Sons
22. Knuefermann P., Nemoto S., Misra A., Nozaki N., Defreitas G., Goyert S. M., Carabello B. A., Mann D. L., Vallejo J. G., CD14-deficient mice are protected against lipopolysaccharide-induced cardiac inflammation and left ventricular dysfunction Circulation 2002 106 20 2608 2615 (Pubitemid 35340698)
23. Chomczynski P., Sacchi N., Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction Analytical Biochemistry 1987 162 1 156 159 (Pubitemid 17064313)
24. Bhatia M., Moochhala S., Role of inflammatory mediators in the pathophysiology of acute respiratory distress syndrome Journal of Pathology 2004 202 2 145 156 (Pubitemid 38208651)
25. Albrecht I., Tapmeier T., Zimmermann S., Frey M., Heeg K., Dalpke A., Toll-like receptors differentially induce nucleosome remodelling at the IL-12p40 promoter EMBO Reports 2004 5 2 172 177 (Pubitemid 38401197)
26. Saito T., Yamamoto T., Kazawa T., Gejyo H., Naito M., Expression of toll-like receptor 2 and 4 in lipopolysaccharide-induced lung injury in mouse Cell and Tissue Research 2005 321 1 75 88 (Pubitemid 40984841)
27. Mayer A. K., Muehmer M., Mages J., Gueinzius K., Hess C., Heeg K., Bals R., Lang R., Dalpke A. H., Differential recognition of TLR-dependent microbial ligands in human bronchial epithelial cells Journal of Immunology 2007 178 5 3134 3142 (Pubitemid 46333195)
28. Leemans J. C., Heikens M., Van Kessel K. P. M., Florquin S., Van der Poll T., Lipoteichoic acid and peptidoglycan from Staphylococcus aureus synergistically induce neutrophil influx into the lungs of mice Clinical and Diagnostic Laboratory Immunology 2003 10 5 950 953 (Pubitemid 37129512)
29. van Zoelen M. A. D., De Vos A. F., Larosa G. J., Draing C., Von Aulock S., van der Poll T., Intrapulmonary delivery of ethyl pyruvate attenuates lipopolysaccharide- and lipoteichoic acid-induced lung inflammation in vivo Shock 2007 28 5 570 575 (Pubitemid 350287442)
30. Sabroe I., Dower S. K., Whyte M. K. B., The role of Toll-like receptors in the regulation of neutrophil migration, activation, and apoptosis Clinical Infectious Diseases 2005 41 7, supplement S421 S426
31. Reutershan J., Basit A., Galkina E. V., Ley K., Sequential recruitment of neutrophils into lung and bronchoalveolar lavage fluid in LPS-induced acute lung injury American Journal of Physiology 2005 289 5 L807 L815
32. Schwartz D. A., Quinn T. J., Thorne P. S., Sayeed S., Yi AE. K., Krieg A. M., CpG motifs in bacterial DNA cause inflammation in the lower respiratory tract Journal of Clinical Investigation 1997 100 1 68 73 (Pubitemid 27311244)
33. Yamamoto S., Tin-Tin W.-S., Ahmed S., Kobayashi T., Fujimaki H., Effect of ultrafine carbon black particles on lipoteichoic acid-induced early pulmonary inflammation in BALB/c mice Toxicology and Applied Pharmacology 2006 213 3 256 266 (Pubitemid 43817117)
34. Corbel M., Boichot E., Lagente V., Role of gelatinases MMP-2 and MMP-9 in tissue remodeling following acute lung injury Brazilian Journal of Medical and Biological Research 2000 33 7 749 754
35. Gibbs D. F., Shanley T. P., Warner R. L., Murphy H. S., Varani J., Johnson K. J., Role of matrix metalloproteinases in models of macrophage-dependent acute lung injury: evidence for alveolar macrophage as source of proteinases American Journal of Respiratory Cell and Molecular Biology 1999 20 6 1145 1154 (Pubitemid 129503232)
36. Hoffmann U., Bertsch T., Dvortsak E., Liebetrau C., Lang S., Liebe V., Huhle G., Borggrefe M., Brueckmann M., Matrix-metalloproteinases and their inhibitors are elevated in severe sepsis: prognostic value of TIMP-1 in severe sepsis Scandinavian Journal of Infectious Diseases 2006 38 10 867 872 (Pubitemid 44489515)
37. Lanchou J., Corbel M., Tanguy M., Germain N., Boichot E., Theret N., Clement B., Lagente V., Malledant Y., Imbalance between matrix metalloproteinases (MMP-9 and MMP-2) and tissue inhibitors of metalloproteinases (TIMP-1 and TIMP-2) in acute respiratory distress syndrome patients Critical Care Medicine 2003 31 2 536 542 (Pubitemid 36232952)
38. Beeh K. M., Beier J., Kornmann O., Buhl R., Sputum matrix metalloproteinase-9, tissue inhibitor of metalloprotinease-1, and their molar ratio in patients with chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis and healthy subjects Respiratory Medicine 2003 97 6 634 639 (Pubitemid 36675664)
39. Ekekezie I. I., Thibeault D. W., Simon S. D., Norberg M., Merrill J. D., Ballard R. A., Ballard P. L., Truog W. E., Low levels of tissue inhibitors of metalloproteinases with a high matrix metalloproteinase-9/tissue inhibitor of metalloproteinase-1 ratio are present in tracheal aspirate fluids of infants who develop chronic lung disease Pediatrics 2004 113 6 1709 1714 (Pubitemid 38697980)
40. Martin E. L., Sheikh T. A., Leco K. J., Lewis J. F., Veldhuizen R. A. W., Contribution of alveolar macrophages to the response of the TIMP-3 null lung during a septic insult American Journal of Physiology 2007 293 3 L779 L789