Factors predictive of inappropriateness in requests for parenteral antimicrobials for therapeutic purposes: A study in a small teaching hospital in Brazil

Scandinavian Journal of Infectious Diseases

Volumn 43, Issue 6-7, 2011, Pages 528-535

  Kawanami, Gustavo Hideki ^a   Fortaleza, Carlos Magno Castelo Branco ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

antimicrobial stewardship; Antimicrobials; cross sectional study

Indexed keywords

ACICLOVIR; AMINOGLYCOSIDE; ANTIBIOTIC AGENT; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; BETA LACTAMASE INHIBITOR PLUS PENICILLIN; CEPHALOSPORIN; GLYCOPEPTIDE; MACROLIDE; PENICILLIN G; QUINOLONE; UNCLASSIFIED DRUG;

ADULT; ANTIMICROBIAL THERAPY; ARTICLE; BRAZIL; CONTROLLED STUDY; DRUG USE; FEMALE; HUMAN; INAPPROPRIATE PRESCRIBING; INFECTION; INFECTION CONTROL; INTENSIVE CARE; MAJOR CLINICAL STUDY; MALE; PATIENT REFERRAL; PERITONITIS; PRESCRIPTION; REQUEST FOR PARENTERAL ANTIMICROBIAL; TEACHING HOSPITAL; URINARY TRACT INFECTION;

AGED; AGED, 80 AND OVER; ANTI-BACTERIAL AGENTS; BRAZIL; CROSS-SECTIONAL STUDIES; DRUG THERAPY; FEMALE; GUIDELINE ADHERENCE; HOSPITALS, TEACHING; HUMANS; INAPPROPRIATE PRESCRIBING; INFUSIONS, INTRAVENOUS; MALE; MIDDLE AGED;

EID: 79959209200     PISSN: 00365548     EISSN: 16511980     Source Type: Journal    
DOI: 10.3109/00365548.2011.565795     Document Type: Article

References (39)

1. van der Meer JW, Gyssens IC. Quality of antimicrobial drug prescription in hospital. Clin Microbiol Infect 2001;7(Suppl6):12-5. (Pubitemid 33730238)
2. Iannini P, Mandell L, Felmingham J, Patou G, Tillotson GS. Adverse cutaneous reactions and drugs: a focus on antimicrobials. J Chemother 2006;18:127-39. (Pubitemid 43774286)
3. Owens RC Jr. QT prolongation with antimicrobial agents: understanding the significance. Drugs 2004;64:1091-124.
4. Hookman P, Barkin JS. Clostridium difficile associated infection, diarrhea and colitis. World J Gastroenterol 2009;15:1554-80.
5. Goldmann DA, Weinstein RA, Wenzel RP, Tablan OC, Duma RJ, Gaynes RP, et al. Strategies to prevent and control the emergence and spread of antimicrobial-resistant microorganisms in hospitals. A challenge to hospital leadership. JAMA 1996;275:234-40. (Pubitemid 26028565)
6. Safdar N, Maki DG. The commonality of risk factors for nosocomial colonization and infection with antimicrobial-resistant Staphylococcus aureus, Enterococcus, Gram-negative bacilli, Clostridium difficile, and Candida. Ann Intern Med 2002;136:834-44. (Pubitemid 34568654)
7. Tacconelli E. Antimicrobial use: risk driver of multidrug resistant microorganisms in healthcare settings. Curr Opin Infect Dis 2009;22:352-8.
8. Kollef MH. Inadequate antimicrobial treatment: an important determinant of outcome for hospitalized patients. Clin Infect Dis 2000;31(Suppl 4):S131-8.
9. Rüttimann S, Keck B, Hartmeier C, Maetzel A, Bucher HC. Long-term antibiotic cost savings from a comprehensive intervention program in a medical department of a university-affiliated teaching hospital. Clin Infect Dis 2004;38:348-56. (Pubitemid 38200110)
10. Sipahi OR. Economics of antibiotic resistance. Expert Rev Anti Infect Ther 2008;6:523-39.
11. Fishman N. Antimicrobial stewardship. Am J Med 2006;119(Suppl 1):S53-61.
12. Dellit TH, Owens RC, McGowan JE Jr, Gerding DN, Weinstein RA, Burke JP, et al. Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America guidelines for developing an institutional program to enhance antimicrobial stewardship. Clin Infect Dis 2007;44:159-77. (Pubitemid 46084814)
13. Ng CK, Wu TC, Chan WM, Leung YS, Li CK, Tsang DN, et al. Clinical and economic impact of an antibiotics stewardship programme in a regional hospital in Hong Kong. Qual Saf Health Care 2008;17:387-92.
14. Martin C, Ofotokun I, Rapp R, Empey K, Armitstead J, Pomeroy C, et al. Results of an anti microbial control program at a university hospital. Am J Health Syst Pharm 2005;62:732-8. (Pubitemid 40462843)
15. Davey P, Brown E, Fenelon L, Finch R, Gould I, Hartman G, et al. Interventions to improve antibiotic prescribing practices for hospital inpatients. Cochrane Database Syst Rev 2005;4:CD003543.
16. Tunkel AR, Hartman BJ, Kaplan SL, Kaufman BA, Roos KL, Scheld WM, et al. Practice guidelines for the management of bacterial meningitis. Clin Infect Dis 2004;39:1267-84. (Pubitemid 39458512)
17. Mandell LA, Bartlett JG, Dowell SF, File TM Jr, Musher DM, Whitney C, et al. Update of practice guidelines for the management of community-acquired pneumonia in immunocompetent adults. Clin Infect Dis 2003;37:1405-33. (Pubitemid 37494668)
18. American Thoracic Society, Infectious Diseases Society of America. Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia. Am J Respir Crit Care Med 2005;171:388-416.
19. Guerrant RL, Van Gilder T, Steiner TS, Thielman NM, Slutsker L, Tauxe RV, et al. Practice guidelines for the management of infectious diarrhea. Clin Infect Dis 2001;32:331-51. (Pubitemid 32173618)
20. Solomkin JS, Mazuski JE, Baron EJ, Sawyer RG, Nathens AB, DiPiro JT, et al. Guidelines for the selection of anti-infective agents for complicated intra-abdominal infections. Clin Infect Dis 2003;37:997-1005. (Pubitemid 37323652)
21. Warren JW, Abrutyn E, Hebel JR, Johnson JR, Schaeffer AJ, Stamm WE. Guidelines for antimicrobial treatment of uncomplicated acute bacterial cystitis and acute pyelonephritis in women. Infectious Diseases Society of America (IDSA). Clin Infect Dis 1999;29:745-58. (Pubitemid 30256361)
22. Nicolle LE, Bradley S, Colgan R, Rice JC, Schaeffer A, Hooton TM. Infectious Diseases Society of America guidelines for the diagnosis and treatment of asymptomatic bacteriuria in adults. Clin Infect Dis 2005;40:643-54. (Pubitemid 40381336)
23. Stevens DL, Bisno AL, Chambers HF, Everett ED, Dellinger P, Goldstein EJ, et al. Practice guidelines for the diagnosis and management of skin and soft-tissue infections. Clin Infect Dis 2005;41:1373-406.
24. Lipsky BA, Berendt AR, Deery HG, Embil JM, Joseph WS, Karchmer AW, et al. Diagnosis and treatment of diabetic foot infections. Clin Infect Dis 2004;39: 885-910. (Pubitemid 39328144)
25. Kunin CM, Tupasi T, Craig WA. Use of antibiotics. A brief exposition of the problem and some tentative solutions. Ann Intern Med 1973;79:555-60.
26. Jones SR, Pannell J, Barks J, Yanchick YA, Bratton T, Browne R, et al. The effect of an educational program upon hospital antibiotic use. Am J Med Sci 1977;273:79-85. (Pubitemid 8081377)
27. Roberts C. Modelling patterns of agreement for nominal scales. Stat Med 2008;27:810-30. (Pubitemid 351350924)
28. Greenland S. Modeling and variable selection in epidemiologic analysis. Am J Public Health 1989;79:340-9. (Pubitemid 19077878)
29. MacDougall C, Polk RE. Antimicrobial stewardship programs in health care systems. Clin Microbiol Rev 2005;18:638-56. (Pubitemid 41504509)
30. Apisarnthanarak A, Danchaivijitr S, Khawcharoenporn T, Limsrivilai J, Warachan B, Bailey TC, et al. Effectiveness of education and antibiotic-control program in a tertiary care hospital in Thailand. Clin Infect Dis 2006; 42:768-75. (Pubitemid 43363930)
31. Willemsen I, Groenhuijzen A, Bogaers D, Stuurman A, van Keulen P, Kluytmans J. Appropriateness of antimicrobial therapy measured by repeated prevalence surveys. Antimicrob Agents Chemother 2007;51: 864-7. (Pubitemid 46355268)
32. Erbay A, Colpan A, Bodur H, Cevik MA, Samore MH, Ergönül O. Evaluation of antibiotic use in a hospital with an antibiotic restriction policy. Int J Antimicrob Agents 2003;21:308-12. (Pubitemid 36397962)
33. Tünger O, Dinç G, Ozbakkaloglu B, Atman UC, Algün U. Evaluation of rational antibiotic use. Int J Antimicrob Agents 2000;15:131-5. (Pubitemid 30347254)
34. Erbay A, Bodur H, Akinci E, Colpan A. Evaluation of antibiotic use in intensive care units of a tertiary care hospital in Turkey. J Hosp Infect 2005;59:53-61. (Pubitemid 39618966)
35. Apisarnthanarak A, Danchaivijitr S, Bailey TC, Fraser VJ. Inappropriate antibiotic use in a tertiary care center in Thailand: an incidence study and review of experience in Thailand. Infect Control Hosp Epidemiol 2006;27:416-20. (Pubitemid 43736110)
36. Hecker MT, Aron DC, Patel NP, Lehmann MK, Donskey CJ. Unnecessary use of antimicrobials in hospitalized patients: current patterns of misuse with an emphasis on the antianaerobic spectrum of activity. Arch Intern Med 2003;163:972-8. (Pubitemid 36519743)
37. Tan JA, Naik VN, Lingard L. Exploring obstacles to proper timing of prophylactic antibiotics for surgical site infections. Qual Saf Health Care 2006;15:32-8. (Pubitemid 43275523)
38. Raineri E, Pan A, Mondello P, Acquarolo A, Candiani A, Crema L. Role of the infectious diseases specialist consultant on the appropriateness of antimicrobial therapy prescription in an intensive care unit. Am J Infect Control 2008;36:283-90. (Pubitemid 351622018)
39. Landis JR, Koch GG. The measurement of observer agreement for categorical data. Biometrics 1977;33:159-74. (Pubitemid 8054849)