ME3738 enhances the effect of interferon and inhibits hepatitis C virus replication both in vitro and in vivo

Journal of Hepatology

Volumn 55, Issue 1, 2011, Pages 11-18

  Abe, Hiromi ^a,c   Imamura, Michio ^a,b   Hiraga, Nobuhiko ^a,b   Tsuge, Masataka ^a,b   Mitsui, Fukiko ^a,b   Kawaoka, Tomokazu ^a,b   Takahashi, Shoichi ^a,b   Ochi, Hidenori ^b,c   Maekawa, Toshiro ^c   Hayes, C Nelson ^a,c   Tateno, Chise ^b,d   Yoshizato, Katsutoshi ^b,d   Murakami, Shoichi ^e   Yamashita, Nobuyuki ^e   Matsuhira, Takashi ^e   Asai, Kenji ^e   Chayama, Kazuaki ^a,b,c  

^a HIROSHIMA UNIVERSITY   (Japan)

^b HIROSHIMA UNIVERSITY   (Japan)

^c INST OF PHYS AND CHEMICAL RESEARCH   (Japan)

^d PhoenixBio USA Corporation   (Japan)

^e MEIJI SEIKA KAISHA LTD   (Japan)

Author keywords

Human hepatocyte chimeric mouse; Interferon stimulated genes

Indexed keywords

2',5' OLIGOADENYLATE SYNTHETASE; 22BETA METHOXYOLEAN 12 ENE 3BETA, 24 DIOL; ALPHA INTERFERON; HEPATITIS B CORE ANTIGEN; ME 3738; SERUM ALBUMIN; SOYASAPOGENOL B; UNCLASSIFIED DRUG; VIRUS RNA;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG POTENTIATION; GENE EXPRESSION; GENE EXPRESSION SYSTEM; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIVER INJURY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPLICON; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA REPLICATION; TREATMENT DURATION; VIRUS INHIBITION; VIRUS REPLICATION;

ANIMALS; ANTIVIRAL AGENTS; BASE SEQUENCE; CELL LINE; DISEASE MODELS, ANIMAL; DRUG SYNERGISM; HEPACIVIRUS; HEPATITIS C, CHRONIC; HEPATOCYTES; HUMANS; INTERFERON TYPE I, RECOMBINANT; MICE; MICE, SCID; OLEANOLIC ACID; REPLICON; RNA, VIRAL; TRANSPLANTATION CHIMERA; VIRUS REPLICATION;

EID: 79958840246     PISSN: 01688278     EISSN: 01688278     Source Type: Journal    
DOI: 10.1016/j.jhep.2010.10.017     Document Type: Article

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