Detection of adeno- and lentiviral (HIV1) contaminations on laboratory surfaces as a tool for the surveillance of biosafety standards

Journal of Applied Microbiology

Volumn 111, Issue 1, 2011, Pages 70-82

  Bagutti, C ^a   Alt, M ^a   Schmidlin, M ^a   Vogel, G ^a,b   Vogeli U ^a   Brodmann, P ^a  

^a Biosafety Laboratory   (Switzerland)

^b MABRITEC AG   (Switzerland)

Author keywords

Detection; Microbial contamination; Virus(es)

Indexed keywords

BIOHAZARDS; CENTRIFUGES; CONTAMINATION; DNA; POLYMERASE CHAIN REACTION; RESEARCH LABORATORIES; RNA;

DETECTION; HOTSPOTS; INFECTIVITY ASSAY; INNER WALLS; MICROBIAL CONTAMINATION; REAL-TIME PCR; REAL-TIME PCR ASSAY; SAFETY PRECAUTIONS; SWITZERLAND; VIRUS(ES);

VIRUSES;

VIRUS DNA; VIRUS RNA;

BIOSAFETY; CENTRIFUGE; DETECTION METHOD; HEALTH RISK; INFECTIVITY; LABORATORY METHOD; POLYMERASE CHAIN REACTION; REAL TIME; VIRUS;

ADENOVIRUS 5; ARTICLE; BIOSAFETY; HUMAN IMMUNODEFICIENCY VIRUS 1; HYGIENE; LABORATORY; NONHUMAN; REAL TIME POLYMERASE CHAIN REACTION; STANDARD; SWITZERLAND; VIRAL CONTAMINATION; VIRUS DETECTION;

SWITZERLAND;

HUMAN ADENOVIRUS TYPE 5; LENTIVIRUS;

EID: 79958836147     PISSN: 13645072     EISSN: 13652672     Source Type: Journal    
DOI: 10.1111/j.1365-2672.2011.05042.x     Document Type: Article

References (49)

1. Alba, R., Bosch, A. and Chillon, M. (2005) Gutless adenovirus: last-generation adenovirus for gene therapy. Gene Ther 12(Suppl 1), S18-S27.
2. Altschul, S.F., Gish, W., Miller, W., Myers, E.W. and Lipman, D.J. (1990) Basic local alignment search tool. J Mol Biol 215, 403-410.
3. Bennett, A. and Parks, S. (2006) Microbial aerosol generation during laboratory accidents and subsequent risk assessment. J Appl Microbiol 100, 658-663.
4. Benson, D.A., Karsch-Mizrachi, I., Lipman, D.J., Ostell, J. and Wheeler, D.L. (2008) GenBank. Nucleic Acids Res 36, D25-D30.
5. Bett, A.J., Haddara, W., Prevec, L. and Graham, F.L. (1994) An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3. Proc Natl Acad Sci USA 91, 8802-8806.
6. Boone, S.A. and Gerba, C.P. (2007) Significance of fomites in the spread of respiratory and enteric viral disease. Appl Environ Microbiol 73, 1687-1696.
7. Bouard, D., Alazard-Dany, D. and Cosset, F.L. (2009) Viral vectors: from virology to transgene expression. Br J Pharmacol 157, 153-165.
8. Currie, L.A. (1995) Nomenclature in evaluation of analytical methods including detection and quantification capabilities (IUPAC Recommendations 1995). Pure Appl Chem 67, 1699-1723.
9. Dedieu, J.F., Vigne, E., Torrent, C., Jullien, C., Mahfouz, I., Caillaud, J.M., Aubailly, N., Orsini, C. et al. (1997) Long-term gene delivery into the livers of immunocompetent mice with E1/E4-defective adenoviruses. J Virol 71, 4626-4637.
10. Dull, T., Zufferey, R., Kelly, M., Mandel, R.J., Nguyen, M., Trono, D. and Naldini, L. (1998) A third-generation lentivirus vector with a conditional packaging system. J Virol 72, 8463-8471.
11. Ehrengruber, M.U., Muhlebach, S.G., Sohrman, S., Leutenegger, C.M., Lester, H.A. and Davidson, N. (2000) Modulation of early growth response (EGR) transcription factor-dependent gene expression by using recombinant adenovirus. Gene 258, 63-69.
12. Engelhardt, J.F., Ye, X., Doranz, B. and Wilson, J.M. (1994) Ablation of E2A in recombinant adenoviruses improves transgene persistence and decreases inflammatory response in mouse liver. Proc Natl Acad Sci USA 91, 6196-6200.
13. European Union (2003) Regulation (EC) No. 1829/2003 on genetically modified food and feed of 22. September 2003. 1829/2003.
14. Fallaux, F.J., Bout, A., Van Der Velde, I., Van Den Wollenberg, D.J., Hehir, K.M., Keegan, J., Auger, C., Cramer, S.J. et al. (1998) New helper cells and matched early region 1-deleted adenovirus vectors prevent generation of replication-competent adenoviruses. Hum Gene Ther 9, 1909-1917.
15. Gilman Duane, E.A. and Fink, R.C. (2006) Primary barriers and equipment-associated hazards. In Biological Safety: Principles and Practices, 4th edn ed. Fleming, D.O. and Hunt, D.L. pp. 295-301. Washington, DC: ASM Press.
16. Graham, F.L. (1991) Manipulation of adenovirus vectors. Methods Mol Biol 7, 20.
17. Harding, A.L. and Brandt Byers, K. (2006) Epidemiology of laboratory-associated infections. In Biological Safety: Principles and Practices, 4th edn ed. Fleming, D.O. and Hunt, D.L. pp. 35-54. Washington, DC: ASM Press.
18. Harper, G.J. (1981) Contamination of the environment by special purpose centrifuges used in clinical laboratories. J Clin Pathol 34, 1114-1123.
19. Harper, G.J. (1984) Evaluation of sealed containers for use in centrifuges by a dynamic microbiological test method. J Clin Pathol 37, 1134-1139.
20. Hehir, K.M., Armentano, D., Cardoza, L.M., Choquette, T.L., Berthelette, P.B., White, G.A., Couture, L.A., Everton, M.B. et al. (1996) Molecular characterization of replication-competent variants of adenovirus vectors and genome modifications to prevent their occurrence. J Virol 70, 8459-8467.
21. Higashikawa, F. and Chang, L. (2001) Kinetic analyses of stability of simple and complex retroviral vectors. Virology 280, 124-131.
22. Holland, P.M., Abramson, R.D., Watson, R. and Gelfand, D.H. (1991) Detection of specific polymerase chain reaction product by utilizing the 5'-3' exonuclease activity of Thermus aquaticus DNA polymerase. Proc Natl Acad Sci U S A 88, 7276-7280.
23. Howarth, J.L., Lee, Y.B. and Uney, J.B. (2010) Using viral vectors as gene transfer tools (Cell Biology and Toxicology Special Issue: ETCS-UK 1day meeting on genetic manipulation of cells). Cell Biol Toxicol 26, 1-20.
24. Kochanek, S., Clemens, P.R., Mitani, K., Chen, H.H., Chan, S. and Caskey, C.T. (1996) A new adenoviral vector: replacement of all viral coding sequences with 28kb of DNA independently expressing both full-length dystrophin and beta-galactosidase. Proc Natl Acad Sci U S A 93, 5731-5736.
25. Kramer, A., Schwebke, I. and Kampf, G. (2006) How long do nosocomial pathogens persist on inanimate surfaces? A systematic review. BMC Infect Dis 6, 130.
26. Lochmuller, H., Jani, A., Huard, J., Prescott, S., Simoneau, M., Massie, B., Karpati, G. and Acsadi, G. (1994) Emergence of early region 1-containing replication-competent adenovirus in stocks of replication-defective adenovirus recombinants (delta E1+delta E3) during multiple passages in 293 cells. Hum Gene Ther 5, 1485-1491.
27. Miyoshi, H., Blomer, U., Takahashi, M., Gage, F.H. and Verma, I.M. (1998) Development of a self-inactivating lentivirus vector. J Virol 72, 8150-8157.
28. Naldini, L., Blomer, U., Gallay, P., Ory, D., Mulligan, R., Gage, F.H., Verma, I.M. and Trono, D. (1996) In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 272, 263-267.
29. Osinde, M., Clavaguera, F., May-Nass, R., Tolnay, M. and Dev, K.K. (2008) Lentivirus Tau (P301S) expression in adult amyloid precursor protein (APP)-transgenic mice leads to tangle formation. Neuropathol Appl Neurobiol 34, 523-531.
30. Parks, R.J., Chen, L., Anton, M., Sankar, U., Rudnicki, M.A. and Graham, F.L. (1996) A helper-dependent adenovirus vector system: removal of helper virus by Cre-mediated excision of the viral packaging signal. Proc Natl Acad Sci U S A 93, 13565-13570.
31. Pauwels, K., Gijsbers, R., Toelen, J., Schambach, A., Willard-Gallo, K., Verheust, C., Debyser, Z. and Herman, P. (2009) State-of-the-art lentiviral vectors for research use: risk assessment and biosafety recommendations. Curr Gene Ther 9, 459-474.
32. Qu, Z., Wolfraim, L.A., Svaren, J., Ehrengruber, M.U., Davidson, N. and Milbrandt, J. (1998) The transcriptional corepressor NAB2 inhibits NGF-induced differentiation of PC12 cells. J Cell Biol 142, 1075-1082.
33. Rheinbaben, F., Schunemann, S., Gross, T. and Wolff, M.H. (2000) Transmission of viruses via contact in ahousehold setting: experiments using bacteriophage straight phiX174 as a model virus. J Hosp Infect 46, 61-66.
34. Rubinson, D.A., Dillon, C.P., Kwiatkowski, A.V., Sievers, C., Yang, L., Kopinja, J., Rooney, D.L., Zhang, M. et al. (2003) A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference. Nat Genet 33, 401-406.
35. Rusin, P., Maxwell, S. and Gerba, C. (2002) Comparative surface-to-hand and fingertip-to-mouth transfer efficiency of gram-positive bacteria, gram-negative bacteria, and phage. J Appl Microbiol 93, 585-592.
36. Rutjes, S.A., Lodder-Verschoor, F., Tijssen, J.P. and De Roda Husman, A.M. (2011) Development and application of a tool to assess laboratory hygiene in contained use facilities. Appl Environ Microbiol 77, 1383-1388.
37. Rutter, D.A. and Evans, C.G. (1972) Aerosol hazards from some clinical laboratory apparatus. Br Med J 1, 594-597.
38. Schiedner, G., Hertel, S. and Kochanek, S. (2000) Efficient transformation of primary human amniocytes by E1 functions of Ad5: generation of new cell lines for adenoviral vector production. Hum Gene Ther 11, 2105-2116.
39. Schmidlin, M., Alt, M., Vogel, G., Voegeli, U., Brodmann, P. and Bagutti, C. (2010) Contaminations of laboratory surfaces with Staphylococcus aureus are affected by the carrier status of laboratory staff. J Appl Microbiol 109, 1284-1293.
40. Sinn, P.L., Sauter, S.L. and Mccray, P.B. Jr (2005) Gene therapy progress and prospects: development of improved lentiviral and retroviral vectors - design, biosafety, and production. Gene Ther 12, 1089-1098.
41. Stern, E.L., Johnson, J.W., Vesley, D., Halbert, M.M., Lawrence, B.S., Williams, L.E. and Blume, P. (1974) Aerosol production associated with clinical laboratory procedures. Am J Clin Pathol 62, 591-600.
42. The Federal Authorities of the Swiss Confederation (1999a) Ordinance on Occupational Safety in Biotechnology (Arbeitnehmerschutzverordnung, SAMV) of 25. August 1999. SR 832.321.
43. The Federal Authorities of the Swiss Confederation (1999b) Ordinance on the Contained Use of Organisms (Containment Ordinance, CO) of 25.August 1999. SR. 814.912.
44. Valtierra, H.N. (2008) Stability of viral pathogens in the laboratory environment. Appl Biosafety J 13, 21-26.
45. Waiblinger, H.U., Graf, N., Mäde, D., Woll, K., Busch, U., Holland, B., Pilsl, H., Naeumann, G. et al. (2007) "Technically Unavoidable" in Terms of Genetically Modified Organisms - an Approach for Food Control. J Verbr Lebensm 2, 126-129.
46. Weber, D.J., Rutala, W.A., Miller, M.B., Huslage, K. and Sickbert-Bennett, E. (2010) Role of hospital surfaces in the transmission of emerging health care-associated pathogens: norovirus, Clostridium difficile, and Acinetobacter species. Am J Infect Control 38, S25-S33.
47. Weinberg, D.H. and Ketner, G. (1986) Adenoviral early region 4 is required for efficient viral DNA replication and for late gene expression. J Virol 57, 833-838.
48. Zufferey, R. (2002) Production of lentiviral vectors. Curr Top Microbiol Immunol 261, 107-121.
49. Zufferey, R., Nagy, D., Mandel, R.J., Naldini, L. and Trono, D. (1997) Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo. Nat Biotechnol 15, 871-875.