A facile synthesis of indole-furan conjugates via integration of convergent and linear domino reactions

Tetrahedron

Volumn 67, Issue 29, 2011, Pages 5142-5149

  Yang, Yan ^a   Gao, Meng ^a   Wu, Liu Ming ^a   Deng, Cong ^a   Zhang, Dong Xue ^a   Gao, Yang ^a   Zhu, Yan Ping ^a   Wu, An Xin ^a  

^a CENTRAL CHINA NORMAL UNIVERSITY   (China)

Author keywords

Biheteroaryls; Domino reaction; Friedel Crafts alkylation; Furan; Indole; Paal Knorr cyclization

Indexed keywords

1 [4 (1H INDOL 3 YL) 2 METHYL 5 PHENYLFURAN 3 YL]ETHANONE; 3 [2,5 BIS(4 METHOXYPHENYL) 4 (METHYLTHIO)FURAN 3 YL] 1H INDOLE; 3 [4 (METHYLTHIO) 2,5 BIS(4 NITROPHENYL)FURAN 3 YL] 1H INDOLE; 3 [4 (METHYLTHIO) 2,5 BIS(4 TOLYLFURAN) 3 YL] 1H INDOLE; 3 [4 (METHYLTHIO) 2,5 BIS(NAPHTHALEN 2 YL)FURAN 3 YL] 1H INDOLE; 3 [4 (METHYLTHIO) 2,5 DIPHENYLFURAN 3 YL] 1H INDOLE; [4 (1H INDOL 3 YL) 2,5 DIPHENYLFURAN 3 YL](PHENYL)METHANONE; ETHYL 4 (1 METHYL 1H INDOL 3 YL) 2,5 DIPHENYLFURAN 3 CARBOXYLIC ACID; ETHYL 4 (1H INDOL 3 YL) 2 (3 NITROPHENYL) 5 PHENYLFURAN 3 CARBOXYLIC ACID; ETHYL 4 (1H INDOL 3 YL) 2 PHENYL 5 (4 TOLYLFURAN) 3 CARBOXYLIC ACID; ETHYL 4 (1H INDOL 3 YL) 2 PHENYL 5 (THIOPHEN 3 YL)FURAN 3 CARBOXYLIC ACID; ETHYL 4 (1H INDOL 3 YL) 2,5 DIPHENYLFURAN 3 CARBOXYLIC ACID; ETHYL 4 (1H INDOL 3 YL) 5 (4 METHOXYPHENYL) 2 PHENYLFURAN 3 CARBOXYLIC ACID; ETHYL 4 (1H INDOL 3 YL) 5 (4 NITROPHENYL) 2 PHENYLFURAN 3 CARBOXYLIC ACID; ETHYL 4 (1H INDOL 3 YL) 5 (NAPHTHALEN 1 YL) 2 PHENYLFURAN 3 CARBOXYLIC ACID; ETHYL 4 (1H INDOL 3 YL) 5 (NAPHTHALEN 2 YL) 2 PHENYLFURAN 3 CARBOXYLIC ACID; ETHYL 4 (1H INDOL 3 YL) 5 PHENYL 2 (3,4,5 TRIMETHOXYPHENYL)FURAN 3 CARBOXYLIC ACID; ETHYL 4 (1H INDOL 3 YL) 5 PHENYL 2,2' BIFURAN 3 CARBOXYLIC ACID; ETHYL 5 (3,4 DICHLOROPHENYL) 4 (1H INDOL 3 YL) 2 PHENYLFURAN 3 CARBOXYLIC ACID; ETHYL 5 (4 BROMOPHENYL) 4 (1H INDOL 3 YL) 2 PHENYLFURAN 3 CARBOXYLIC ACID; ETHYL 5 (4 CHLOROPHENYL) 4 (1H INDOL 3 YL) 2 PHENYLFURAN 3 CARBOXYLIC ACID; ETHYL 5 (4 FLUOROPHENYL) 4 (1H INDOL 3 YL) 2 PHENYLFURAN 3 CARBOXYLIC ACID; ETHYL 5 (4 HYDROXYPHENYL) 4 (1H INDOL 3 YL) 2 PHENYLFURAN 3 CARBOXYLIC ACID; ETHYL 5 (BENZOFURAN 2 YL) 4 (1H INDOL 3 YL) 2 PHENYLFURAN 3 CARBOXYLIC ACID; FURAN DERIVATIVE; INDOLE DERIVATIVE; KETONE; METHYL 2 (4 CHLOROPHENYL) 4 (1H INDOL 3 YL) 5 PHENYLFURAN 3 CARBOXYLIC ACID; METHYL 2 (4 FLUOROPHENYL) 4 (1H INDOL 3 YL) 5 PHENYLFURAN 3 CARBOXYLIC ACID; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTICLE; CYCLIZATION; DRUG CONJUGATION; DRUG STRUCTURE; DRUG SYNTHESIS; FRIEDEL CRAFTS REACTION; PAAL KNORR CYCLIZATION; PRIORITY JOURNAL; REACTION OPTIMIZATION;

EID: 79958770155     PISSN: 00404020     EISSN: 14645416     Source Type: Journal    
DOI: 10.1016/j.tet.2011.05.058     Document Type: Article

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