Hemodynamic changes during aging associated with cerebral blood flow and impaired cognitive function

Neurobiology of Aging

Volumn 21, Issue 2, 2000, Pages 257-269

  Ajmani, R S ^a   Metter, E J ^a   Jaykumar, R ^b   Ingram, D K ^c   Spangler, E L ^c   Abugo, O O ^c   Rifkind, J M ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b CENTRAL LEATHER RESEARCH INSTITUTE   (India)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Aging; Alzheimer's disease; Cerebral blood flow; Hemorheology; Oxidative stress

Indexed keywords

AMYLOID; RECOMBINANT ERYTHROPOIETIN;

ADULT; AGE; AGED; AGING; ALZHEIMER DISEASE; BLOOD FLOW VELOCITY; BLOOD RHEOLOGY; BRAIN BLOOD FLOW; COGNITIVE DEFECT; CONFERENCE PAPER; CONTROLLED STUDY; ELASTICITY; ERYTHROCYTE; ERYTHROCYTE AGGREGATION; FEMALE; HEMODYNAMICS; HUMAN; LIPID PEROXIDATION; MALE; MAZE TEST; NONHUMAN; OXIDATIVE STRESS; OXYGEN SUPPLY; PRIORITY JOURNAL; RAT;

ADULT; AGED; AGING; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; BLOOD VISCOSITY; CEREBROVASCULAR CIRCULATION; COGNITION DISORDERS; ERYTHROCYTE VOLUME; ERYTHROPOIETIN, RECOMBINANT; FEMALE; HEMATOCRIT; HEMODYNAMIC PROCESSES; HUMANS; MALE; MAZE LEARNING; MIDDLE AGED; RATS; RATS, INBRED F344; RHEOLOGY;

EID: 0034603608     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-4580(00)00118-4     Document Type: Conference Paper

References (37)

1. Ajmani R.S., Rifkind J.M. Hemorheological changes during human aging. Gerontology. 44:1998;111-120.
2. Bush A.I., Beyreuther K., Masters C.L. The βA4 amyloid protein recursor in human circulation. Nitsch R.M., Growdon J.H., Corkin S., Wurtman R.J. Alzhemier's disease amyloid precursor proteins, signal transduction, neural transplantation. 1993;175-181 NYAcad Sci, New York.
3. Butterfield D.A., Markesbery W.R. Specificity of biophysical and biochemical alterations in erythrocyte membranes in neurological disorders-Huntington'disease, Friedreich's ataxia, Alzheimer's disease, amyotrophic lateral sclerosis, and myotonic and duchenne muscular dystrophy. J Neurol Sci. 47:1980;261-271.
4. Cavestri R., Radices L., Ferrarini F., Longhini M., Longhini E. Influence of erythrocyte aggregability and plasma fibrinogen concentration on cerebral blood flow with aging. Acta Nerurol Scand. 85:1992;292-298.
5. Choe M., Jackson C., Yu B.P. Lipid peroxidation contributes to age related membrane rigidity. Free Rad Biol Med. 18:1995;977-984.
6. Claus J.J., Breteler M.M.B., Hasan D., Krenning E.P., Bots M.L., Grobbee D.E., Swieten, Harskamp V.F., Hofman A. Regional cerebral blood flow and cerebrovascular risk factors in the elderly population. Neurobiol Aging. 19:1998;57-64.
7. Crawford J.G. Alzheimer's disease risk factors as related to cerebral blood flow. Med Hypotheses. 46:1996;367-377.
8. Dacie JV, Lewis SM. Practical hematology. Churchill Livingston, 6th Ed., 1984. New York.
9. Danon D., Bologna N.B., Gavendo S. Memory performance of young and old subjects related to their erythrocyte characteristics. Exp Gerontol. 27:1992;275-285.
10. De Leo M.E., Borrello S., Passantino M., Palazzotti B., Mordente A., Daniele A., Filippini V., Galeotti T., Masullo C. Oxidative stress and overexpression of manganese superoxide dismutase in patients with Alzheimer's disease. Neurosci Lett. 10:1998;173-176.
11. Dyrks T., Dyrks E., Hartmann T., Masters C., Beyreuther K. Amyloidogenicity of beta A4 and beta A4-bearing amyloid protein precursor fragments by metal-catalyzed oxidation. J Biol Chem. 267:1992;546-554.
12. Goldman H.R., Berman S., Gerson S.L., Murphy S.L., Altman H.J. Correlation of behavioral and cerebrovascular functions in the aging rat. Neurobiol Aging. 8:1987;409-416.
13. Hansen F., Mangell P., Sonesson B., Lanne T. Diameter and compliance in the human common carotid artery - variation with age and sex. Ultrasound Med Biol. 21:1995;1-9.
14. Hengemihle J.M., Abugo O., Rifkind J., Spangler E., Danon D., Ingram D.K. Chronic treatment with human recombinant erythropoietin increases hematocrit and improves water maze performance in mice. Physiol Behav. 15:1995;877-887.
15. Ingram D.K. Complex maze learning in rodents progress and potential for modeling age related memory dysfunction . Golstein A.L. Biomedical advances in aging. 1990;175-181 Plenum Press, New York.
16. Expert panel on blood rheology. Guidelines selection of laboratory test for monitoring the acute phase response. J Clin Pathol. 41:1988;1203-1212.
17. Jain S.K. Hyperglycemia can cause membrane lipid peroxidation and osmotic fragility in human red blood cells. J Biochem. 264:1989;21340-21345.
18. Jian M., Jiajung F., Zhengren G., Chen H., Bo Y., Fong W., Duoning W., Shufen S. A new hypothesis about the relationship between free radical reactions and hemorheological properties in vivo. Med Hypoth. 41:1993;516-520.
19. Jucker M., Battig K., Meierruge W. Effects of aging and vincamine derivatives on pericapillary microenvironment - stereological characterization of the cerebral capillary network. Neurobiol Aging. 11:1990;39-46.
20. Keaney J.F. Jr, Vita J.A. Atherosclerosis, oxidative stress and antioxidant protection in endothelium-derived relaxing factor action. Prog Cardiovasc Dis. 38:1995;129-154.
21. Merkle D.L., Cheng C.H., Castellino F.J., Chibber B.A. Modulation of fibrin assembly and polymerization by the beta-amyloid of Alzheimer's disease. Blood Coagul Fibrinolysis. 7:1996;650-658.
22. Miklossy J., Taddei K., Martins R., Escher G., Kraftsik R., Pillevuit O., Lepori D., Campiche M. Alzheimer disease curly fibers and tangles in organs other than brain . J Neuropathol Exp Neurol. 58:1999;803-814.
23. Nagai Y., Kemper M.K., Earley C.J., Metter E.J. Blood-flow velocities and their relationships in carotid and middle cerebral arteries. Ultrasound Med Biol. 24:1998;1131-1136.
24. Nagai Y., Metter E.J., Earley C.J., Kemper M.K., Becker L.C., Lakatta E.G., Fleg J.L. Increased carotid artery intimal-medial thickness in asymptomatic older subjects with exercise-induced myocardial ischemia. Circulation. 98:1998;1504-1509.
25. Peddada R.R., Abugo O.O., Kelly J.F., Roth G.S., Rifkind J.M. Effect of cholesterol contents in diet on capillary flow of rat erythrocytes. Part II: mechanical properties . Clin Hemorheol Microcirc. 17:1997;445-447.
26. Poli G., Parola M. Oxidative damage and fibrogensis. Free Rad Biol Med. 22:1997;287-305.
27. Pourcelot L. Diagnostic ultrasound for cerebral vascular diseases. Donald I., Levi S. Present and future of diagnostic ultrasound. 1976;141-147 Kooyker, Rotterdam.
28. Rifkind J.M., Ajmani R.S., Heim J. Impaired hemorheology in the aged associated with oxidative stress. Adv Exp Med Biol. 428:1997;7-13.
29. Rifkind J.M., Abugo O.O., Peddada R.R., Patel N., Speer D., Balagopalakrishna C., Danon D., Ingram D.K., Spangler E.L. Maze learning impairment is associated with stress hemopoiesis induced by chronic treatment of aged rats with human recombinant erythropoietin. Life Sci. 64:1999;237-247.
30. Roher A.E., Chaney M.O., Kuo Y.M., Webster S.D., Stine W.B., Haverkamp L.J., Woods A.S., Cotter R.J., Tuohy J.M., Krafft G.A., Bonnell B.S., Emmerling M.R. Morphology and toxicity of A beta-(1-42) dimer derived from neuritic and vascular amyloid deposits of Alzheimer's disease. J Biol Chem. 271:1996;20631-20635.
31. Simmons M.A., Schneider C.R. Amyloids βpeptides act directly on single neuron. Neurosci Lett. 150:1993;133-136.
32. Skoog I, Kalaria RN, Breteler MM. Vascular factors and Alzheimer disease. Alzheimer Dis Assoc Disord 1999; Vol. 13 Suppl 3:S106-14.
33. Snaedal J., Kristinsson J., Gunnarsdottir S., Olafsdottir, Baldvinsson M., Johannesson T. Copper, ceruloplasmin, and superoxide dismutase in patients with Alzheimer's disease a case-control study . Dement Geriatr Cogn Disord. 9:1998;239-242.
34. Spangler E.L., Rigby P., Ingram D.K. Scopolamine impairs learning performance of rats in a 14-unit T-maze. Pharmacol Biochem Behav. 25:1986;673-679.
35. Tanaka H., Dinenno F.A., Hunt B.E., Jones P.P., DeSouza C.A., Seals D.R. Hemodynamic sequelae of age-related increases in arterial stiffness in healthy women. Am J Cardiol. 82:1998;1152-1155.
36. Torre la de J., Mussivand T. Can disturbed brain microcirculation cause Alzheimer's disease? Neurol Res. 15:1993;146-153.
37. Tseng B.P., Esler W.P., Clish C.B., Stimson E.R., Ghilardi J.R., Vinters H.V., Mantyh P.W., Lee J.P., Maggio J.E. Deposition of monomeric, not oligomeric, Abeta mediates growth of Alzheimer's disease amyloid plaques in human brain preparations. Biochemistry. 38:1999;10424-10431.