Les lymphocytes T régulateurs CD4+CD25+: Vers une immunomodulation thérapeutique?

Medecine/Sciences

Volumn 18, Issue 11, 2002, Pages 1066-1068

  Salomon, Beno໭t ^a  

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 79958763911     PISSN: 07670974     EISSN: 19585381     Source Type: Journal    
DOI: 10.1051/medsci/200218111066     Document Type: Article

References (12)

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2. Salomon B, Lenschow DJ, Rhee L, et al. B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes. Immunity 2000; 12: 431-40.
3. Green EA, Choi Y, Flavell RA. Pancreatic lymph nodederived CD4 (+)CD25 (+) Treg cells: highly potent regulators of diabetes that require TRANCE-RANK signals.Immunity 2002; 16:183-91.
4. Apostolou I, Sarukhan A, Klein L, von Boehmer H. Origin of regulatory T cells with known specificity for antigen. Nat Immunol 2002; 3: 756-63.
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6. Itoh M, Takahashi T, Sakaguchi N, et al. Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance. J Immunol1999; 162: 5 317-26.
7. Jordan MS, Boesteanu A, Reed AJ, et al. Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide. Nat Immunoi 2001; 2: 301-6.
8. Jonuleit H, Schmitt E, Stassen M, Tuettenberg A, Knop J, Enk AH. Identification and functional characterization of human CD4 (+)CD25 (+) T cells with regulatory properties isolated from peripheral blood. J Exp Med 2001; 193: 1285-94.
9. Kukreja A, Cost G, Marker J, et al. Multiple immunoregulatory defects in type-1 diabetes. J Clin Invest 2002; 109: 131-40.
10. Gregori S, Casorati M, Amuchastegui S, Smiroldo S, Cavalli AM, Adorini L. Regulatory T cells induced by 1alpha, 25-dihydroxyvitamin d (3) and mycophenolate mofetil treatment mediate transplantation tolerance. J Immunol 2001; 167: 1945-53.
11. H ara M, Kingsley CI, Niimi M, et al. IL-10 is required for regulatory T cells to mediate tolerance to alloantigens in vivo. J Immunol 2001; 166: 3789-96.
12. Cohen, JL, Trenado A, Vasey D, Klatzmann D, Salomon BL. CD4 (+)CD25 (+) immunoregulatory T cells: new therapeutics for graft-versus-host disease. J Exp Med 2002; 196: 401-6.