-
1
-
-
0031761892
-
Tumor and endothelial cell invasion of basement membranes. The matrigel chemoinvasion assay as a tool for dissecting molecular mechanisms
-
Albini A. (1998). Tumor and endothelial cell invasion of basement membranes. The matrigel chemoinvasion assay as a tool for dissecting molecular mechanisms. Pathol Oncol Res, 4, 230-41.
-
(1998)
Pathol Oncol Res
, vol.4
, pp. 230-241
-
-
Albini, A.1
-
2
-
-
1642579534
-
Evidence that activation of nuclear factor-kappaB is essential for the cytotoxic effects of doxorubicin and its analogues
-
Ashikawa K, Shishodia S, Fokt I, et al. (2004). Evidence that activation of nuclear factor-kappaB is essential for the cytotoxic effects of doxorubicin and its analogues. Biochem Pharmacol, 67, 353-64.
-
(2004)
Biochem Pharmacol
, vol.67
, pp. 353-364
-
-
Ashikawa, K.1
Shishodia, S.2
Fokt, I.3
-
3
-
-
33644505791
-
Prognostic factors for osteosarcoma of the extremity treated with neoadjuvant chemotherapy
-
Bacci G, Longhi A, Versari M, et al. (2006). Prognostic factors for osteosarcoma of the extremity treated with neoadjuvant chemotherapy. Cancer, 106, 1154-61.
-
(2006)
Cancer
, vol.106
, pp. 1154-1161
-
-
Bacci, G.1
Longhi, A.2
Versari, M.3
-
5
-
-
0036467661
-
Prognostic factors in high-grade osteosarcoma of the extremities or trunk: an analysis of 1. 702 patients treated on neoadjuvant cooperative osteosarcoma study group protocols
-
Bielack SS, Kempf-Bielack B, Delling G, et al. (2002). Prognostic factors in high-grade osteosarcoma of the extremities or trunk: an analysis of 1,702 patients treated on neoadjuvant cooperative osteosarcoma study group protocols. J Clin Oncol, 20, 776-90.
-
(2002)
J Clin Oncol
, vol.20
, pp. 776-790
-
-
Bielack, S.S.1
Kempf-Bielack, B.2
Delling, G.3
-
6
-
-
73649132981
-
Inactive Wnt/β-catenin pathway in conventional high-grade osteosarcoma
-
Cai Y, Mohseny AB, Karperien M, et al. (2010). Inactive Wnt/(-catenin pathway in conventional high-grade osteosarcoma. J Pathol, 220, 24-33.
-
(2010)
J Pathol
, vol.220
, pp. 24-33
-
-
Cai, Y.1
Mohseny, A.B.2
Karperien, M.3
-
7
-
-
48249098887
-
Wnt10b induces chemotaxis of osteosarcoma and correlates with reduced survival
-
Chen K, Fallen S, Abaan HO, et al. (2008). Wnt10b induces chemotaxis of osteosarcoma and correlates with reduced survival. Pediatr Blood Cancer, 51, 349-55.
-
(2008)
Pediatr Blood Cancer
, vol.51
, pp. 349-355
-
-
Chen, K.1
Fallen, S.2
Abaan, H.O.3
-
8
-
-
67650077096
-
Gene expression profiling of alpha-radiation-induced rat osteosarcomas: identification of dysregulated genes involved in radiationinduced tumorigenesis of bone
-
Daino K, Ugolin N, Altmeyer-Morel S, et al. (2009). Gene expression profiling of alpha-radiation-induced rat osteosarcomas: identification of dysregulated genes involved in radiationinduced tumorigenesis of bone. Int J Cancer, 125, 612-20.
-
(2009)
Int J Cancer
, vol.125
, pp. 612-620
-
-
Daino, K.1
Ugolin, N.2
Altmeyer-Morel, S.3
-
9
-
-
0036781671
-
beta-catenin interacts with and inhibits NF-kappa B in human colon and breast cancer
-
Deng J, Miller SA, Wang HY, et al. (2002). beta-catenin interacts with and inhibits NF-kappa B in human colon and breast cancer. Cancer Cell, 2, 323-34.
-
(2002)
Cancer Cell
, vol.2
, pp. 323-334
-
-
Deng, J.1
Miller, S.A.2
Wang, H.Y.3
-
10
-
-
50649124475
-
Dominant negative LRP5 decreases tumorigenicity and metastasis of osteosarcoma in an animal model
-
Guo Y, Rubin EM, Xie J, et al. (2008). Dominant negative LRP5 decreases tumorigenicity and metastasis of osteosarcoma in an animal model. Clin Orthop Relat Res, 466, 2039-45.
-
(2008)
Clin Orthop Relat Res
, vol.466
, pp. 2039-2045
-
-
Guo, Y.1
Rubin, E.M.2
Xie, J.3
-
11
-
-
34447279476
-
Blocking Wnt/LRP5 signaling by a soluble receptor modulates the epithelial to mesenchymal transition and suppresses met and metalloproteinases in osteosarcoma Saos-2 cells
-
Guo Y, Zi X, Koontz Z, et al. (2007). Blocking Wnt/LRP5 signaling by a soluble receptor modulates the epithelial to mesenchymal transition and suppresses met and metalloproteinases in osteosarcoma Saos-2 cells. J Orthop Res, 25, 964-71.
-
(2007)
J Orthop Res
, vol.25
, pp. 964-971
-
-
Guo, Y.1
Zi, X.2
Koontz, Z.3
-
12
-
-
0036888309
-
Cytoplasmic and/or nuclear accumulation of the beta-catenin protein is a frequent event in human osteosarcoma
-
Haydon RC, Deyrup A, Ishikawa A, et al. (2002). Cytoplasmic and/or nuclear accumulation of the beta-catenin protein is a frequent event in human osteosarcoma. Int J Cancer, 102, 338-42.
-
(2002)
Int J Cancer
, vol.102
, pp. 338-342
-
-
Haydon, R.C.1
Deyrup, A.2
Ishikawa, A.3
-
13
-
-
0036108620
-
Cadherin and catenin alterations in human cancer
-
Hajra KM, Fearon ER, et al. (2002). Cadherin and catenin alterations in human cancer. Genes Chromosomes Cancer, 34, 255-68.
-
(2002)
Genes Chromosomes Cancer
, vol.34
, pp. 255-268
-
-
Hajra, K.M.1
Fearon, E.R.2
-
14
-
-
10744221160
-
Betacatenin up-regulates the expression of the urokinase plasminogen activator in human colorectal tumors
-
Hiendlmeyer E, Regus S, Wassermann S, et al. (2004). Betacatenin up-regulates the expression of the urokinase plasminogen activator in human colorectal tumors. Cancer Res, 64, 1209-14.
-
(2004)
Cancer Res
, vol.64
, pp. 1209-1214
-
-
Hiendlmeyer, E.1
Regus, S.2
Wassermann, S.3
-
15
-
-
0742287878
-
Expression of LDL receptor-related protein 5 (LRP5) as a novel marker for disease progression in high-grade osteosarcoma
-
Hoang BH, Kubo T, Healey JH, et al. (2004). Expression of LDL receptor-related protein 5 (LRP5) as a novel marker for disease progression in high-grade osteosarcoma. Int J Cancer, 109, 106-11.
-
(2004)
Int J Cancer
, vol.109
, pp. 106-111
-
-
Hoang, B.H.1
Kubo, T.2
Healey, J.H.3
-
16
-
-
9244240664
-
Dickkopf 3 inhibits invasion and motility of saos-2 osteosarcoma cells by modulating the wnt-beta-catenin pathway
-
Hoang BH, Kubo T, Healey JH, et al. (2004). Dickkopf 3 inhibits invasion and motility of saos-2 osteosarcoma cells by modulating the wnt-beta-catenin pathway. Cancer Res, 64, 2734-9.
-
(2004)
Cancer Res
, vol.64
, pp. 2734-2739
-
-
Hoang, B.H.1
Kubo, T.2
Healey, J.H.3
-
17
-
-
0142029993
-
Cytoplasmic and/ or nuclear staining of beta-catenin is associated with lung metastasis
-
Iwaya K, Ogawa H, Kuroda M, et al. (2003). Cytoplasmic and/ or nuclear staining of beta-catenin is associated with lung metastasis. Clin Exp Metastasis, 20, 525-9.
-
(2003)
Clin Exp Metastasis
, vol.20
, pp. 525-529
-
-
Iwaya, K.1
Ogawa, H.2
Kuroda, M.3
-
18
-
-
0033052527
-
Frequent beta-catenin abnormalities in bone and soft-tissue tumors
-
Iwoa K, Miyoshi Y, Nawa G, et al. (1999). Frequent beta-catenin abnormalities in bone and soft-tissue tumors. Jpn J Cancer Res, 90, 205-9.
-
(1999)
Jpn J Cancer Res
, vol.90
, pp. 205-209
-
-
Iwoa, K.1
Miyoshi, Y.2
Nawa, G.3
-
19
-
-
79954438230
-
Osteosarcoma: improvement in survival limited to high-grade patients only
-
DOI:10.1007/s00432-010-0923-7
-
Jawad MU, Cheung MC, Clarke J, et al. (2010). Osteosarcoma: improvement in survival limited to high-grade patients only. J Cancer Res Clin Oncol, DOI:10.1007/s00432-010-0923-7
-
(2010)
J Cancer Res Clin Oncol
-
-
Jawad, M.U.1
Cheung, M.C.2
Clarke, J.3
-
20
-
-
65249167488
-
Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma,and targeted disruption accelerates osteosarcomagenesis in mice
-
Kansara M, Tsang M, Kodjabachian L, et al. (2009). Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma,and targeted disruption accelerates osteosarcomagenesis in mice. J Clin Invest, 119, 837-51.
-
(2009)
J Clin Invest
, vol.119
, pp. 837-851
-
-
Kansara, M.1
Tsang, M.2
Kodjabachian, L.3
-
21
-
-
33745298519
-
Nuclear factor-kappaB in cancer development and progression
-
Karin M. (2006). Nuclear factor-kappaB in cancer development and progression. Nature, 441, 431-6.
-
(2006)
Nature
, vol.441
, pp. 431-436
-
-
Karin, M.1
-
22
-
-
42549164807
-
Wnt signalling and its impact on development and cancer
-
Klaus A, Birchmeier W. (2008). Wnt signalling and its impact on development and cancer. Nature Rev Cancer, 8, 387-98.
-
(2008)
Nature Rev Cancer
, vol.8
, pp. 387-398
-
-
Klaus, A.1
Birchmeier, W.2
-
23
-
-
77954375987
-
Antitumor activity of natural compounds, curcumin and PKF118-310
-
DOI: 10.1007/s10637-009-9311-z
-
Leow PC, Tian Q, Ong ZY, et al. (2009). Antitumor activity of natural compounds, curcumin and PKF118-310, as Wnt/ betacatenin antagonists against human osteosarcoma cells. Invest New Drugs, DOI: 10.1007/s10637-009-9311-z.
-
(2009)
as Wnt/ betacatenin antagonists against human osteosarcoma cells. Invest New Drugs
-
-
Leow, P.C.1
Tian, Q.2
Ong, Z.Y.3
-
24
-
-
13044281685
-
Target genes of β-catenin-T cell-factor/lymphoid-enhancer-factor signaling in human colorectal carcinomas
-
Mann B, Gelos M, Siedow A, et al. (1999). Target genes of β-catenin-T cell-factor/lymphoid-enhancer-factor signaling in human colorectal carcinomas. Proc Natl Acad Sci, 96, 1603-8.
-
(1999)
Proc Natl Acad Sci
, vol.96
, pp. 1603-1608
-
-
Mann, B.1
Gelos, M.2
Siedow, A.3
-
25
-
-
0034053069
-
Wnt signaling in oncogenesis and embryogenesis--a look outside the nucleus
-
Peifer M, Polakis P. (2000). Wnt signaling in oncogenesis and embryogenesis--a look outside the nucleus. Science, 287, 1606-9.
-
(2000)
Science
, vol.287
, pp. 1606-1609
-
-
Peifer, M.1
Polakis, P.2
-
26
-
-
0028020606
-
Relationship of chemotherapy-induced necrosis and surgical margins to local recurrence in osteosarcoma
-
Picci P, Sangiorgi L, Rougraff BT, et al. (1994). Relationship of chemotherapy-induced necrosis and surgical margins to local recurrence in osteosarcoma. J Clin Oncol, 12, 2699-705,.
-
(1994)
J Clin Oncol
, vol.12
-
-
Picci, P.1
Sangiorgi, L.2
Rougraff, B.T.3
-
27
-
-
0033895709
-
Wnt signaling and cancer
-
Polakis P. (2000). Wnt signaling and cancer. Genes Dev, 14, 1837-51.
-
(2000)
Genes Dev
, vol.14
, pp. 1837-1851
-
-
Polakis, P.1
-
28
-
-
62549151288
-
Downregulation of Wnt2 and beta-catenin by siRNA suppresses malignant glioma cell growth
-
Pu P, Zhang Z, Kang C, et al. (2009). Downregulation of Wnt2 and beta-catenin by siRNA suppresses malignant glioma cell growth. Cancer Gene Ther, 16, 351-61.
-
(2009)
Cancer Gene Ther
, vol.16
, pp. 351-361
-
-
Pu, P.1
Zhang, Z.2
Kang, C.3
-
29
-
-
1542336952
-
Rational siRNA design for RNA interference
-
Reynolds A, Leake D, Boese Q, et al. (2004). Rational siRNA design for RNA interference. Nat Biotechnol, 22, 326-30.
-
(2004)
Nat Biotechnol
, vol.22
, pp. 326-330
-
-
Reynolds, A.1
Leake, D.2
Boese, Q.3
-
30
-
-
0037426578
-
Membrane-type 1 matrix metalloproteinase: a key enzyme for tumor invasion
-
Seiki, M. (2003). Membrane-type 1 matrix metalloproteinase: a key enzyme for tumor invasion. Cancer Lett, 194, 1-11.
-
(2003)
Cancer Lett
, vol.194
, pp. 1-11
-
-
Seiki, M.1
-
31
-
-
0037194578
-
Identification of membrane-type matrix metalloproteinase-1 as a target of the β-catenin/Tcf4 complex in human colorectal cancers
-
Takahashi M, Tsunoda T, Seiki M, et al. (2002). Identification of membrane-type matrix metalloproteinase-1 as a target of the (-catenin/Tcf4 complex in human colorectal cancers. Oncogene, 21, 5861-7.
-
(2002)
Oncogene
, vol.21
, pp. 5861-5867
-
-
Takahashi, M.1
Tsunoda, T.2
Seiki, M.3
-
32
-
-
33745584805
-
Epigenetic modifications in osteogenic differentiation and transformation
-
Thomas D, Kansara M. (2006). Epigenetic modifications in osteogenic differentiation and transformation. J Cell Biochem, 98, 757-69.
-
(2006)
J Cell Biochem
, vol.98
, pp. 757-769
-
-
Thomas, D.1
Kansara, M.2
-
33
-
-
0037388638
-
Small interfering RNAs directed against beta-catenin inhibit the in vitro and in vivo growth of colon cancer cells
-
Verma UN, Surabhi RM, Schmaltieg A, et al. (2003). Small interfering RNAs directed against beta-catenin inhibit the in vitro and in vivo growth of colon cancer cells. Clin Cancer Res, 9, 1291-300.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 1291-1300
-
-
Verma, U.N.1
Surabhi, R.M.2
Schmaltieg, A.3
-
34
-
-
0029858387
-
TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB
-
Wang CY, Mayo MW, Baldwin AS, et al. (1996). TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB. Science, 274, 784-7.
-
(1996)
Science
, vol.274
, pp. 784-787
-
-
Wang, C.Y.1
Mayo, M.W.2
Baldwin, A.S.3
-
35
-
-
0032508414
-
NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation
-
Wang CY, Mayo MW, Korneluk RG, et al. (1998). NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science, 281, 1680-3.
-
(1998)
Science
, vol.281
, pp. 1680-1683
-
-
Wang, C.Y.1
Mayo, M.W.2
Korneluk, R.G.3
-
36
-
-
30944433183
-
Wnt/beta-catenin signaling inhibits death receptor-mediated apoptosis and promotes invasive growth of HNSCC
-
Yang F, Zeng Q, Yu G, et al. (2006). Wnt/beta-catenin signaling inhibits death receptor-mediated apoptosis and promotes invasive growth of HNSCC. Cell Signal, 18, 679-87.
-
(2006)
Cell Signal
, vol.18
, pp. 679-687
-
-
Yang, F.1
Zeng, Q.2
Yu, G.3
-
37
-
-
36048967529
-
siRNA-mediated betacatenin knockdown in human hepatoma cells results in decreased growth and survival
-
Zeng G, Apte U, Cieply B, et al. (2007). siRNA-mediated betacatenin knockdown in human hepatoma cells results in decreased growth and survival. Neoplasia, 9, 951-9.
-
(2007)
Neoplasia
, vol.9
, pp. 951-959
-
-
Zeng, G.1
Apte, U.2
Cieply, B.3
-
38
-
-
0042588468
-
Membrane type-matrix metalloproteinases (MT-MMP)
-
Zucker S, Pei D, Cao J, Lopez-Otin C, et al. (2003). Membrane type-matrix metalloproteinases (MT-MMP). Curr Top Dev Biol, 54, 1-74.
-
(2003)
Curr Top Dev Biol
, vol.54
, pp. 1-74
-
-
Zucker, S.1
Pei, D.2
Cao, J.3
Lopez-Otin, C.4
|