-
1
-
-
0029026094
-
Identical mutations in the p53 tumor suppressor gene in the glial and the sarcomutous components of gliosarcomas suggest a common origin from glial cells
-
BIERNAT, W., AGUZZI, A., SURE, U., GRANT, J.W., KLEIHUES, P. and HEGI, M.E., Identical mutations in the p53 tumor suppressor gene in the glial and the sarcomutous components of gliosarcomas suggest a common origin from glial cells. J. Neuropathol. exp. Neurol., 54, 651-656 (1995).
-
(1995)
J. Neuropathol. Exp. Neurol.
, vol.54
, pp. 651-656
-
-
Biernat, W.1
Aguzzi, A.2
Sure, U.3
Grant, J.W.4
Kleihues, P.5
Hegi, M.E.6
-
2
-
-
0025896435
-
Morphological, immunocytochemical and growth characteristics of three human glioblastomasestablished in vitro
-
BILZER, T., STAVROU, D., DAHME, E., KEIDITSCH, E., BÜRRIG, K.K. ANZIL, A.P. and WECHSLER, W., Morphological, immunocytochemical and growth characteristics of three human glioblastomasestablished in vitro. Virchow Arch. A. Pathol. Anat., 418, 281-293 (1991).
-
(1991)
Virchow Arch. A. Pathol. Anat.
, vol.418
, pp. 281-293
-
-
Bilzer, T.1
Stavrou, D.2
Dahme, E.3
Keiditsch, E.4
Bürrig, K.K.5
Anzil, A.P.6
Wechsler, W.7
-
3
-
-
0029562169
-
Analysis of the p16 gene. CDKN2, in 17 Australian melanoma kindreds
-
CONZEN, S.D. and COLE, C.N., Analysis of the p16 gene. CDKN2, in 17 Australian melanoma kindreds. Oncogene, 11, 2289-2294 (1995).
-
(1995)
Oncogene
, vol.11
, pp. 2289-2294
-
-
Conzen, S.D.1
Cole, C.N.2
-
4
-
-
0029967152
-
Silencing of p16/CDKN2 expression in human gliomas by methylation and chromatin condensation
-
COSTELLO, J.F., BERGER, M.S., HUANG, H.-J.S. and CAVENEE, W.K., Silencing of p16/CDKN2 expression in human gliomas by methylation and chromatin condensation. Cencer Res., 56, 2405-2410 (1996).
-
(1996)
Cencer Res.
, vol.56
, pp. 2405-2410
-
-
Costello, J.F.1
Berger, M.S.2
Huang, H.-J.S.3
Cavenee, W.K.4
-
5
-
-
0028970766
-
INK4Bgene) during tumor progression in a sporadic melanoma patient
-
INK4Bgene) during tumor progression in a sporadic melanoma patient. Cancer Res., 55, 5531-5535 (1995).
-
(1995)
Cancer Res.
, vol.55
, pp. 5531-5535
-
-
Glendening, J.M.1
Flores, J.F.2
Walker, G.J.3
Stone, S.4
Albino, A.P.5
Fountain, J.W.6
-
6
-
-
0028875205
-
Methylation of the 5′-CpG island of the P16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing
-
GONZALEZ-ZULUETA, M., BENDER, C.M., YANG, A.S., NGUYEN, T., BEART, R.W. and VAN TURNOUT, J.M., Methylation of the 5′-CpG island of the P16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing. Cancer Res., 55, 4531-4535 (1995).
-
(1995)
Cancer Res.
, vol.55
, pp. 4531-4535
-
-
Gonzalez-Zulueta, M.1
Bender, C.M.2
Yang, A.S.3
Nguyen, T.4
Beart, R.W.5
Van Turnout, J.M.6
-
7
-
-
0024365892
-
Epigenetic changes may contribute to the formation and spontaneous regression of retinoblastoma
-
GREGER, V., PASSARGE, E., HOPPING, W., MESSMER, E. and HORSTHEMKE, B., Epigenetic changes may contribute to the formation and spontaneous regression of retinoblastoma. Hum. Genet., 83, 155-158 (1989).
-
(1989)
Hum. Genet.
, vol.83
, pp. 155-158
-
-
Greger, V.1
Passarge, E.2
Hopping, W.3
Messmer, E.4
Horsthemke, B.5
-
8
-
-
0028072991
-
Silencing of the VHL tumor-suppressor gene by DNA methylation in renal cell carcinoma
-
HERMAN, J.G., LATIF, F., WENG, Y., LERMAN, M.J., ZBAR, B., LIU, S., SAMID, D., DUAN, D.-S.R., GNARRA, J.R., LINEHAN, W.M. and BAYLIN, S.B., Silencing of the VHL tumor-suppressor gene by DNA methylation in renal cell carcinoma. Proc. nat. Acad. Sci. (Wash.), 91, 9700-9704 (1994).
-
(1994)
Proc. Nat. Acad. Sci. (Wash.)
, vol.91
, pp. 9700-9704
-
-
Herman, J.G.1
Latif, F.2
Weng, Y.3
Lerman, M.J.4
Zbar, B.5
Liu, S.6
Samid, D.7
Duan, D.-S.R.8
Gnarra, J.R.9
Linehan, W.M.10
Baylin, S.B.11
-
9
-
-
0026802989
-
Regulation of retinoblastoma protein functions by ectopic expression of human cyclins
-
HINDS, P.W., MITTNACHT, S., DULIC, V., ARNOLD, A., REED, S.I. and WEINBERG, R.A., Regulation of retinoblastoma protein functions by ectopic expression of human cyclins. Cell, 70, 993-1006 (1992).
-
(1992)
Cell
, vol.70
, pp. 993-1006
-
-
Hinds, P.W.1
Mittnacht, S.2
Dulic, V.3
Arnold, A.4
Reed, S.I.5
Weinberg, R.A.6
-
10
-
-
0029736653
-
INK4A, MTS1) and CDK4 genes have frequent mutations of the retinoblastoma gene
-
INK4A, MTS1) and CDK4 genes have frequent mutations of the retinoblastoma gene. Oncogene, 13, 1065-1072 (1996).
-
(1996)
Oncogene
, vol.13
, pp. 1065-1072
-
-
Ichimura, K.1
Schmidt, E.E.2
Goike, H.M.3
Collins, V.P.4
-
11
-
-
0028244964
-
A common region of homozygous deletion in malignant human glioma lies between the IFNα/o gene cluster and the D9S171 locus
-
ICHIMURA, K., SCHMIDT, E.E., YAMAGUCHI, N., JAMES, C.D. and COLLINS, V.P., A common region of homozygous deletion in malignant human glioma lies between the IFNα/o gene cluster and the D9S171 locus. Cancer Res., 54, 3127-3130 (1994).
-
(1994)
Cancer Res.
, vol.54
, pp. 3127-3130
-
-
Ichimura, K.1
Schmidt, E.E.2
Yamaguchi, N.3
James, C.D.4
Collins, V.P.5
-
12
-
-
0028618304
-
Deletion of p16 and p15 genes in brain tumors
-
JEN, J., HARPER, J.W., BIGNER, S.H., BIGNER, D.D., PAPADOPOULOS, N., MARKOWITZ, S., WILLSON, J.K.V., KINZLER, K.W. an VOGELSTEIN, B., Deletion of p16 and p15 genes in brain tumors. Cancer Res., 54, 6353-6358 (1994).
-
(1994)
Cancer Res.
, vol.54
, pp. 6353-6358
-
-
Jen, J.1
Harper, J.W.2
Bigner, S.H.3
Bigner, D.D.4
Papadopoulos, N.5
Markowitz, S.6
Willson, J.K.V.7
Kinzler, K.W.8
Vogelstein, B.9
-
13
-
-
0028121279
-
A cell cycle cycle regulator potentially involved in genesis of many tumor types
-
KAMB, A., GRUIS, N.A., WEAVER-FELDHAUS, J., LIU, Q., HARSHMAN, K., TAVTIGIAN, S.V., STOCKERT, E., DAY, R.S.I., JOHNSON, B.E. and SKOLNICK, M.H., A cell cycle cycle regulator potentially involved in genesis of many tumor types. Science, 264, 436-440 (1994).
-
(1994)
Science
, vol.264
, pp. 436-440
-
-
Kamb, A.1
Gruis, N.A.2
Weaver-Feldhaus, J.3
Liu, Q.4
Harshman, K.5
Tavtigian, S.V.6
Stockert, E.7
Day, R.S.I.8
Johnson, B.E.9
Skolnick, M.H.10
-
14
-
-
0027454445
-
Co-amplification of the CDK4 gene with MDM2 and GLI in human sarcomas
-
KATHIB, Z.A., MATSUSHIME, H., VALENTINE, M., SHAPIRO, D.N., SHERR, C.J. and LOOK, A.T., Co-amplification of the CDK4 gene with MDM2 and GLI in human sarcomas. Cancer Res., 53, 5535-5541 (1993).
-
(1993)
Cancer Res.
, vol.53
, pp. 5535-5541
-
-
Kathib, Z.A.1
Matsushime, H.2
Valentine, M.3
Shapiro, D.N.4
Sherr, C.J.5
Look, A.T.6
-
15
-
-
0027288908
-
Direct binding of cyclin D to the retinoblastoma gene product (pRb) and Rb phosphorylation by the cyclin D-dependent kinase CDK4
-
KATO, J., MATSUSHIME, H., HIEBERT, S.W., EWEN, M.E. and SHERR, C.J., Direct binding of cyclin D to the retinoblastoma gene product (pRb) and Rb phosphorylation by the cyclin D-dependent kinase CDK4. Genes Develop., 7, 331-342 (1993).
-
(1993)
Genes Develop.
, vol.7
, pp. 331-342
-
-
Kato, J.1
Matsushime, H.2
Hiebert, S.W.3
Ewen, M.E.4
Sherr, C.J.5
-
17
-
-
0030032928
-
Mutations of the p16 gene in gliomas
-
KYRITSIS, A.P., ZHANG, B., ZHANG, W., XIAO, M., TAKESHIMA, H., BONDY, M.L., CUNNINGHAM, J.E., LEVIN, V.A. and BRUNER, J., Mutations of the p16 gene in gliomas. Oncogene, 12, 63-67 (1996).
-
(1996)
Oncogene
, vol.12
, pp. 63-67
-
-
Kyritsis, A.P.1
Zhang, B.2
Zhang, W.3
Xiao, M.4
Takeshima, H.5
Bondy, M.L.6
Cunningham, J.E.7
Levin, V.A.8
Bruner, J.9
-
18
-
-
0028087884
-
Pathways leading to glioblastoma multiforme: A molecular analysis of genetic alterations in 65 astrocytic tumors
-
LANG, F.F., MILLER, D.C., KOSLOW, M. and NEWCOMB, E.W., Pathways leading to glioblastoma multiforme: a molecular analysis of genetic alterations in 65 astrocytic tumors. J. Neurosurg., 81, 427-436 (1994).
-
(1994)
J. Neurosurg.
, vol.81
, pp. 427-436
-
-
Lang, F.F.1
Miller, D.C.2
Koslow, M.3
Newcomb, E.W.4
-
19
-
-
0028982932
-
INK4A transcript
-
INK4A transcript. Cancer Res., 55, 2995-2997 (1995).
-
(1995)
Cancer Res.
, vol.55
, pp. 2995-2997
-
-
Mao, L.1
Merlo, A.2
Bedi, G.3
Shapiro, G.I.4
Edwards, C.D.5
Rollins, B.J.6
Sidransky, D.7
-
20
-
-
0029011539
-
5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/ CDKN2/MTSI in human cancers
-
MERLO, A., HERMAN, J.G., MAO, L., LEE, M.J., GABRIELSON, E., BURGER, P.C., BAYLIN, S.B. and SIDRANSKY, D., 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/ CDKN2/MTSI in human cancers. Nature (Med.), 1, 686-692 (1995).
-
(1995)
Nature (Med.)
, vol.1
, pp. 686-692
-
-
Merlo, A.1
Herman, J.G.2
Mao, L.3
Lee, M.J.4
Gabrielson, E.5
Burger, P.C.6
Baylin, S.B.7
Sidransky, D.8
-
21
-
-
0026545619
-
Analysis of gene amplification in archival tissue by differential polymerase chain reaction
-
NEUBAUER, A., NEUBAUER, B., HE, M., EFFERT, P., IGLEHART, D., FRYE, R.A. and LIU, E., Analysis of gene amplification in archival tissue by differential polymerase chain reaction. Oncogene, 7, 1019-1025 (1992).
-
(1992)
Oncogene
, vol.7
, pp. 1019-1025
-
-
Neubauer, A.1
Neubauer, B.2
He, M.3
Effert, P.4
Iglehart, D.5
Frye, R.A.6
Liu, E.7
-
22
-
-
0028986612
-
INK4 expression is frequent in high grade gliomas
-
INK4 expression is frequent in high grade gliomas. Cancer Res., 55, 1941-1945 (1995).
-
(1995)
Cancer Res.
, vol.55
, pp. 1941-1945
-
-
Nishikawa, R.1
Furnari, F.B.2
Lin, H.3
Arap, W.4
Berger, M.S.5
Cavenee, W.K.6
Huang, H.S.7
-
23
-
-
0028275733
-
Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers
-
NOBORI, T., MIURAL, K., WU, D.J., TAKABAYASHI, K. and CARSON, D.A., Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers. Nature (Lond.), 368, 753-756 (1994).
-
(1994)
Nature (Lond.)
, vol.368
, pp. 753-756
-
-
Nobori, T.1
Miural, K.2
D.j, W.U.3
Takabayashi, K.4
Carson, D.A.5
-
24
-
-
0028882666
-
Genetic alterations associated with the evolution and progression of astrocytic brain tumours
-
OHGAKI, H., SCHÄUBLE, B., ZUR HAUSEN, A., VON AMMON, K. and KLEIHUES, P., Genetic alterations associated with the evolution and progression of astrocytic brain tumours. Virchows Arch. 427, 113-118 (1995).
-
(1995)
Virchows Arch.
, vol.427
, pp. 113-118
-
-
Ohgaki, H.1
Schäuble, B.2
Zur Hausen, A.3
Von Ammon, K.4
Kleihues, P.5
-
25
-
-
0028033270
-
INK4 in human cancer
-
INK4 in human cancer. Proc. nat. Acad. Sci. (Wash.), 91, 11045-11049 (1994).
-
(1994)
Proc. Nat. Acad. Sci. (Wash.)
, vol.91
, pp. 11045-11049
-
-
Okamoto, A.1
Demetrick, D.J.2
Spillare, E.A.3
Hagiwara, K.4
Hussain, S.P.5
Bennet, W.P.6
Forrester, K.7
Gerwin, B.8
Serrano, M.9
Beach, D.H.10
Harris, C.C.11
-
26
-
-
0024756969
-
Rapid and sensitive detection of point mutations und DNA polymorphisms using the polymerase chain reaction
-
ORITA, M., SUZUKI, Y., SEKIYA, T. and HAYASHI, K., Rapid and sensitive detection of point mutations und DNA polymorphisms using the polymerase chain reaction. Genomics, 5, 874-879 (1989).
-
(1989)
Genomics
, vol.5
, pp. 874-879
-
-
Orita, M.1
Suzuki, Y.2
Sekiya, T.3
Hayashi, K.4
-
27
-
-
0029119852
-
INK4b genes
-
INK4b genes. Oncogene, 11, 635-645 (1995a).
-
(1995)
Oncogene
, vol.11
, pp. 635-645
-
-
Quelle, D.E.1
Ashmun, R.A.2
Hannon, G.J.3
Rehberger, P.A.4
Trono, D.5
Richter, K.H.6
Walker, C.7
Beach, D.8
Sherr, C.J.9
Serrano, M.10
-
28
-
-
0029587551
-
Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest
-
QUELLE, D.E., ZINDY, F., ASHMUN, R.A. and SHERR, C.J., Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest. Cell, 83, 993-1000 (1995b).
-
(1995)
Cell
, vol.83
, pp. 993-1000
-
-
Quelle, D.E.1
Zindy, F.2
Ashmun, R.A.3
Sherr, C.J.4
-
29
-
-
0029890378
-
Analysis of p53 mutation and epidermal growth factor receptor amplification in recurrent gliomas with malignant progression
-
REIFENBERGER, J., RING, G.U., GIES, U., COBBERS, J.M.J.L., OBERSTRASS, J., AN, H.-X., NIEDERACHER, D., WECHSLER, W. and REIFENBERGER, G., Analysis of p53 mutation and epidermal growth factor receptor amplification in recurrent gliomas with malignant progression. J. Neuropathol. exp. Neurol., 55, 822-831 (1996).
-
(1996)
J. Neuropathol. Exp. Neurol.
, vol.55
, pp. 822-831
-
-
Reifenberger, J.1
Ring, G.U.2
Gies, U.3
Cobbers, J.M.J.L.4
Oberstrass, J.5
An, H.-X.6
Niederacher, D.7
Wechsler, W.8
Reifenberger, G.9
-
30
-
-
0028652269
-
CDKN2 (p16/MTSI) gene deletion or CDK4 amplification occurs in the majority of glioblastomas
-
SCHMIDT, E.E., ICHIMURA, K., REIFENBERGER, G. and COLLINS, V.P., CDKN2 (p16/MTSI) gene deletion or CDK4 amplification occurs in the majority of glioblastomas. Cancer Res., 54, 6321-6324 (1994).
-
(1994)
Cancer Res.
, vol.54
, pp. 6321-6324
-
-
Schmidt, E.E.1
Ichimura, K.2
Reifenberger, G.3
Collins, V.P.4
-
31
-
-
0027769876
-
A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
-
SERRANO, M., HANNON, G.J. and BEACH, D., A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4. Science, 366, 704-707 (1993).
-
(1993)
Science
, vol.366
, pp. 704-707
-
-
Serrano, M.1
Hannon, G.J.2
Beach, D.3
-
32
-
-
0029993450
-
Role of the INK4a locus in tumor suppression and cell mortality
-
SERRANO, M., LEE, H.-W., CHIN, L., CORDON-CARDO, C., BEACH, D. and DEPINHO, R.A., Role of the INK4a locus in tumor suppression and cell mortality. Cell, 85, 27-37 (1996).
-
(1996)
Cell
, vol.85
, pp. 27-37
-
-
Serrano, M.1
Lee, H.-W.2
Chin, L.3
Cordon-Cardo, C.4
Beach, D.5
Depinho, R.A.6
-
33
-
-
0029060657
-
Complex structure and regulation of the p16 (MTSI) locus
-
STONE, S., JIANG, P. DAYANANTH, P., TAVITGIAN, S.V., KATCHER, H., PARRY, D., GORDON, P. and KAMB, A., Complex structure and regulation of the p16 (MTSI) locus. Cancer Res., 55, 2988-2994 (1995).
-
(1995)
Cancer Res.
, vol.55
, pp. 2988-2994
-
-
Stone, S.1
Jiang, P.2
Dayananth, P.3
Tavitgian, S.V.4
Katcher, H.5
Parry, D.6
Gordon, P.7
Kamb, A.8
-
34
-
-
0027407245
-
Subsets of glioblastoma multiforme defined by molecular genetic analysis
-
VON DEIMLING, A., VON AMMON, K., SCHOENFELD, D., WIESTLER, O.D., SEIZINGER, B.R. and LOUIS, D.N., Subsets of glioblastoma multiforme defined by molecular genetic analysis. Brain Pathol., 3, 19-26 (1993).
-
(1993)
Brain Pathol.
, vol.3
, pp. 19-26
-
-
Von Deimling, A.1
Von Ammon, K.2
Schoenfeld, D.3
Wiestler, O.D.4
Seizinger, B.R.5
Louis, D.N.6
-
35
-
-
0030017885
-
Overexpression of the EGF receptor and p53 mutations are mutually exclusive in the evolution of primary and secondary glioblastomas
-
WATANABE, K., TACHIBANA, O., SATO, K., YONEKAWA, Y., KLEIHUES, P. and OHGAKI, H., Overexpression of the EGF receptor and p53 mutations are mutually exclusive in the evolution of primary and secondary glioblastomas. Brain Pathol., 6, 217-224 (1996).
-
(1996)
Brain Pathol.
, vol.6
, pp. 217-224
-
-
Watanabe, K.1
Tachibana, O.2
Sato, K.3
Yonekawa, Y.4
Kleihues, P.5
Ohgaki, H.6
-
36
-
-
0031023126
-
Identification of a novel region of homozygous deletion on chromosome 9p in squamous cell carcinoma of the lung: The locution of a putative tumor suppressor gene
-
WIEST, J.S. and 12 OTHERS, Identification of a novel region of homozygous deletion on chromosome 9p in squamous cell carcinoma of the lung: the locution of a putative tumor suppressor gene. Cancer Res., 57, 1-6 (1997).
-
(1997)
Cancer Res.
, vol.57
, pp. 1-6
-
-
Wiest, J.S.1
|