Cancer cells cultured within collagen I hydrogels exhibit an in vivo solid tumor phenotype

2011 IEEE 37th Annual Northeast Bioengineering Conference, NEBEC 2011

Volumn , Issue , 2011, Pages

  Szot, Christopher S ^a   Buchanan, Cara F ^a   Rylander, Marissa Nichole ^a   Freeman, Joseph W ^a  

^a VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3-D ENVIRONMENTS; ANGIOGENIC FACTOR; BREAST CANCER CELLS; CANCER CELLS; CELL SEEDING DENSITY; COLLAGEN I; HYPOXIC ENVIRONMENTS; IN-VITRO; IN-VIVO; MATRIX; NUTRIENT DIFFUSION; SCAFFOLD THICKNESS; SOLID TUMORS; TUMORIGENESIS; UP-REGULATION;

COLLAGEN; COMPETITION; DISEASES; FLOW MEASUREMENT; GENE EXPRESSION; HYDROGELS; SCAFFOLDS (BIOLOGY); STIFFNESS MATRIX; TUMORS;

CELLS;

EID: 79958752347     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/NEBC.2011.5778721     Document Type: Conference Paper

References (5)

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3. M. J. Paszek, et al., "Tensional homeostasis and the malignant phenotype," Cancer Cell, vol. 8, pp. 241-54, Sep 2005.
4. S. Ramanujan, et al., "Diffusion and convection in collagen gels: implications for transport in the tumor interstitium," Biophys J, vol. 83, pp. 1650-60, Sep 2002.
5. R. Bos, et al., "Hypoxia-inducible factor-1alpha is associated with angiogenesis, and expression of bFGF, PDGF-BB, and EGFR in invasive breast cancer," Histopathology, vol. 46, pp. 31-6, Jan 2005.