Change in expression pattern of TCR-CD3 complex in patients with multiple myeloma

Hematology

Volumn 16, Issue 3, 2011, Pages 143-150

  Li, Yangqiu ^a   Chen, Shaohua ^a   Yang, Lijian ^a   Chen, Si ^a   Lin, Chunlan ^b   Wang, Liang ^a   Lu, Yuhong ^a   Geng, Suxia ^c   Du, Xin ^c   Schmidt, Christian A ^d  

^a JINAN UNIVERSITY   (China)

^b MEDICAL COLLEGE OF JINAN UNIVERSITY   (China)

^c GUANGDONG PROVINCIAL PEOPLE'S HOSPITAL   (China)

^d UNIVERSITY OF GREIFSWALD   (Germany)

Author keywords

Cellular immunodeficiency; Gene expression; MM; TCR

Indexed keywords

BETA 2 MICROGLOBULIN; CELL PROTEIN; LYMPHOCYTE ANTIGEN RECEPTOR; UNCLASSIFIED DRUG; VBETA1 PROTEIN; VBETA13 PROTEIN; VBETA16 PROTEIN; VBETA2 PROTEIN; VBETA20 PROTEIN; VBETA21 PROTEIN; VBETA9 PROTEIN;

ADULT; AGED; ARTICLE; CANCER STAGING; CLINICAL ARTICLE; CLONAL VARIATION; CONTROLLED STUDY; FEMALE; GENE EXPRESSION PROFILING; GENE LOCATION; HUMAN; IMMUNE DEFICIENCY; MALE; MULTIPLE MYELOMA; ONCOGENE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; VBETA1 GENE; VBETA13 GENE; VBETA16 GENE; VBETA2 GENE; VBETA20 GENE; VBETA21 GENE; VBETA9 GENE;

ADULT; AGED; ANTIGENS, CD3; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MIDDLE AGED; MULTIPLE MYELOMA; RECEPTOR-CD3 COMPLEX, ANTIGEN, T-CELL; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; T-LYMPHOCYTES;

EID: 79958733603     PISSN: 10245332     EISSN: 16078454     Source Type: Journal    
DOI: 10.1179/102453311X12953015767491     Document Type: Article

References (47)

1. Kyle RA, Rajkumar SV. Multiple myeloma. Blood 2008;111:2962-2972.
2. z T cells from CML patients. J Transl Med 2010;8:47.
3. Li Y, Chen S, Yang L, Zhou Y, Wu X, Huang M, et al. Clonal expanded TCR Vbeta T cells in patients with APL. Hematology 2005;10:135-139.
4. Rezvany M, Jeddi-Tehrani M, Osterborg A, Kimby E, Wigzell H, Mellstedt H. Oligoclonal TCR BV gene usage in B-cell chronic lymphocytic leukemia: major perturbations are preferentially seen within the CD4 T-cell subset. Blood 1999;94:1063-1069.
5. Chen X, Woiciechowsky A, Raffegerst S, Schendel D, Kolb HJ, Roskrow M. Impaired expression of the CD3-zeta chain in peripheral blood T cells of patients with chronic myeloid leukaemia results in an increased susceptibility to apoptosis. Br J Haematol 2000;111:817-825.
6. Chen S, Yang L, Chen S, Li Y. TCR zeta chain expression in T cells from patients with CML. Hematology 2009;14:95-100.
7. Berenson J, Lichtenstein A. Clonal rearrangement of the beta-T cell receptor gene in multiple myeloma. Leukemia 1989;3:133-136.
8. Pérez-Andres M, Almeida J, Martin-Ayuso M, Moro MJ, Martin-Nuñez G, Galende J, et al. Characterization of bone marrow T cells in monoclonal gammopathy of undetermined significance, multiple myeloma, and plasma cell leukemia demonstrates increased infiltration by cytotoxic/Th1 T cells demonstrating a squed TCR-Vbeta repertoire. Cancer 2006;106:1296-1305.
9. Marťin-Ayuso M, Almeida J, ÉPérez-Andrs M, Cuello R, Galende J, González-Fraile MI, et al. Peripheral blood dendritic cell subsets from patients with monoclonal gammo-pathies show an abnormal distribution and are functionally impaired. Oncologist 2008;13:82-92.
10. Massaia M, Bianchi A, Attisano C, Peola S, Redoglia V, Dianzani U, et al. Detection of hyperreactive T cells in multiple myeloma by multivalent cross-linking of the CD3/TCR complex. Blood 1991;78:1770-1780.
11. Pannetier C, Even J, Kourilsky P. T-cell repertoire diversity and clonal expansions in normal and clinical samples. Immunol Today 1995;16:176-181.
12. Sensi M, Parmiani G. Analysis of TCR usage in human tumors: a new tool for assessing tumor-specific immune response. Immunol Today 1995;16:588-595.
13. Lozeron P, Chabas D, Duprey B, Lyon-Caen O, Liblau R. T cell receptor V beta 5 and V beta 17 clonal diversity in cerebrospinal fluid and peripheral blood lymphocytes of multiple sclerosis patients. Mult Scler 1998;4:154-161.
14. Puisieux I, Even J, Pannetier C, Jotereau F, Favrot M, Kourilsky P. Oligoclonality of tumor-infiltrating lymphocytes from human melanomas. J Immunol 1994;153:2807-2818.
15. Rezvany MR, Jeddi-Tehrani M, Wigzell H, Osterborg A, Mellstedt H. Leukemia-associated monoclonal and oligo-clonal TCR-BV use in patients with B-cell chronic lymphocytic leukemia. Blood 2003;101:1063-1070.
16. Thor Straten P, Guldberg P, Gronbeak K, Hansen MR, Kirkin AF, Seremet T, Zeuthen J, Becker JC:. In situ T cell responses against melanoma comprise high numbers of locally expanded T cell clonatypes. J Immunol 1999;163:443-447.
17. Mami-Chouaib F, Echchakir H, ÉDorothe G, Vergnon I, Chouaib S. Antitumor cytotoxic T-lymphocyte response in human lung carcinoma: identification of a tumor-associated antigen. Immunol Rev 2002;188:114-121.
18. Berenson J, Lichtenstein A. Clonal rearrangement of the beta-T cell receptor gene in multiple myeloma. Leukemia 1989;3:133-136.
19. z T cells in patients with multiple myeloma and paraproteinemia. Blood 1996;87:3297-3306.
20. z T cell expansions are found preferentially in patients with a low tumor burden. Eur J Immunol 1997;27:2245-2252.
21. Raitakari M, Brown RD, Sze D, Yuen E, Barrow L, Nelson M, et al. T-cell expansions in patients with multiple myeloma have a phenotype of cytotoxic T cells. Br J Haematol 2000;110:203-209.
22. Sze DM, Brown RD, Yuen E, Gibson J, Ho J, Raitakari M, et al. Clonal cytotoxic T cells in myeloma. Leuk Lymphoma 2003;44:1667-74.
23. Sze DM, Giesajtis G, Brown RD, Raitakari M, Gibson J, Ho J, et al. Clonal cytotoxic T cells are expanded in myeloma and reside in the CD8(z)CD57(z)CD28(2) compartment. Blood 2001;98:2817-2827.
24. Sze DM. Clonality detection of expanded T-cell populations in patients with multiple myeloma. Methods Mol Med 2005;113:257-267.
25. Call ME, Wucherpfenning KW. The T cell receptor: critical role of the membrane environment in receptor assembly and function. Annu Rev Immunol 2005;23:101-125.
26. Clevers H, Alarcon B, Wileman T, Terhorst C. The T cell receptor/CD3 complex: a dynamic protein ensemble. Annu Rev Immunol 1988;6:629-662.
27. Call ME, Pyrdol J, Wucherpfenning KW. Stoichiometry of the T-cell receptor-CD3 complex and key intermediates assembled in the endoplasmic reticulum. EMBO J 2004;23:2348-2357.
28. Arnett KL, Harrison SC, Wiley DC. Crystal structure of a human CD3-epsilon/delta dimmer in complex with a UCHT1 single-chain antibody fragment. Proc Natl Acad Sci USA 2004;101:16268-16273.
29. Abraham RT, Weiss A. Jurkat T cells and development of the T-cell receptor signaling paradigm. Nat Rev Immunol 2004;4:301-308.
30. Fischer A, de Saint Basile G, le Deist F. CD3 deficiens. Curr Opin Allergy Clin Immunol 2003;5:491-495.
31. Liossis SN, Ding XZ, Dennis GJ, Tsokos GC. Altered pattern of TCR/CD3-mediated protein-tyrosyl phosphorylation in T cells from patients with systemic lupus erythematosus. Deficient expression of the T cell receptor zeta chain. J Clin Invest 1998;101:1448-1457.
32. Solomou EE, Wong S, Visconte V, Gibellini F, Young NS. Decreased TCR zeta-chain expression in T cells from patients with acquired aplastic anaemia. Br J Haematol 2007;138:72-76.
33. Torelli GF, Paolini R, Tatarelli C, Soriani A, Vitale A, Guarini A, et al. Defective expression of the T-cell receptor-CD3 zeta chain in T-cell acute lymphoblastic leukaemia. Br J Haematol 2003;120:201-208.
34. Mozaffari F, Hansson L, Kiaii S, Ju X, Rossmann ED, Rabbani H, et al. Signalling molecules and cytokine production in T cells of multiple myeloma-increased abnormalities with advancing stage. Br J Haematol 2004;124:315-324.
35. Durie BGM, Salmon SE. A clinical staging system for multiple myeloma correlation of measured myeloma cell mass with presenting clinical features, response to treatment, and survival. Cancer 1975;36:842-854.
36. Li Y, Chen S, Yang L, Yin Q, Geng S, Wu X, et al. TRAV and TRBV repertoire, clonality and the proliferative history of umbilical cord blood T cells. Transplant Immunol 2007;18:151-158.
37. z pediatric ALL. Blood 2003;101:2743-2747.
38. z- Tcells from human umbilical cord blood. Hematology 2010;15:230-235.
39. Hadden JW. Immunodeficiency and cancer: prospects for correction. Int Immunopharmacol 2003;3:1061-1071.
40. Gorski J, Yassai M, Zhu X, Kissela B, Kissella B. Circulating T cell repertoire complexity in normal individuals and bone marrow recipients analyzed by CDR3 size spectratyping. J Immunol 1994;152:5109-5119.
41. Assaf C, Hummel M, Dippel E, Goerdt S, Muller HH, Anagnostopoulos I, et al. High detection rate of T-cell receptor beta chain rearrangements in T-cell lymphoproliferations by family specific polymerase chain reaction in combination with the Genescan technique and DNA sequencing. Blood 2000;96:640-646.
42. z- T-cell epitopes. Leukemia 2006;20:1738-1750.
43. Takahashi T, Makiguchi Y, Hinoda Y, Kakiuchi H, Nakagawa N, Imai K, et al. Expression of MUC1 on myeloma cells and induction of HLA-unrestricted CTL against MUC1 from a multiple myeloma patient. J Immunol 1994;153:2102-2109.
44. Kiaii S, Choudhury A, Mozaffari F, Kimby E, Osterborg A, Mellstedt H. Signaling molecules and cytokine production in T cells of patients with B-cell chronic lymphocytic leukemia (B-CLL): comparison of indolent and progressive disease. Med Oncol 2005;22:291-302.
45. Haks MC, Cordaro TA, van den Brakel JH, Haanen JB, de Vries EF, Borst J, et al. A redundant role of the CD3 gamma-immunoreceptor tyrosine-based activation motif in mature T cell function. J Immunol 2001;166:2576-2588.
46. DeJarnette JB, Sommers CL, Huang K, Woodside KJ, Emmons R, Katz K, et al. Specific requirement for CD3epsilon in T cell development. Proc Natl Acad Sci USA 1998;95:14909-14914.
47. Sommers CL, Dejarnette JB, Huang K, Lee J, El-Khoury D, Shores EW, et al. Function of CD3 epsilon-mediated signals in T cell development. J Exp Med 2000;192:913-919.