Induction of MUC5AC mucin by conjugated bile acids in the esophagus involves the phosphatidylinositol 3-kinase/protein kinase C/activator protein-1 pathway

Cancer

Volumn 117, Issue 11, 2011, Pages 2386-2397

  Song, Shumei ^a   Byrd, James C ^a   Guha, Sushovan ^a   Liu, Kai Feng ^a   Koul, Dimpy ^b   Bresalier, Robert S ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF TEXAS   (United States)

Author keywords

Activator protein 1; Barrett esophagus; Bile reflux; MUC5AC mucin; Phosphatidylinositol 3 kinase pathway

Indexed keywords

BILE ACID CONJUGATE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; MUCIN 5AC; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN KINASE C; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BARRETT ESOPHAGUS; CELL CULTURE; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; EPITHELIUM CELL; ESOPHAGEAL ADENOCARCINOMA; ESOPHAGUS; ESOPHAGUS MUCOSA; GASTROESOPHAGEAL REFLUX; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; RAT; TRANSACTIVATION;

ACTIVATOR PROTEIN-1; BARRETT ESOPHAGUS; MUC5AC MUCIN, BILE REFLUX; PHOSPHATIDYLINOSITOL 3-KINASE PATHWAY;

ADENOCARCINOMA; ANIMALS; BARRETT ESOPHAGUS; BILE ACIDS AND SALTS; BILE REFLUX; DISEASE MODELS, ANIMAL; EPITHELIAL CELLS; ESOPHAGEAL NEOPLASMS; ESOPHAGUS; GENE EXPRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MUCIN 5AC; MUCOUS MEMBRANE; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN KINASE C; RATS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION, GENETIC;

EID: 79958705997     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.25796     Document Type: Article

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