Differential expression of Hsp27 in normal oesophagus, Barrett's metaplasia and oesophageal adenocarcinomas

British Journal of Cancer

Volumn 79, Issue 3-4, 1999, Pages 595-603

  Soldes, Os ^a   Kuick, Rd ^b   Thompson II, Ia ^a   Hughes, Sj ^a   Orringer, Mb ^a   Iannettoni, Md ^a   Hanash, Sm ^b   Beer, Dg ^a,c  

^a Section of Orthopaedic Surgery   (United States)

^b UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Adenocarcinoma; Barrett's metaplasia; Cancer; Heat shock protein 27; Oesophagus

Indexed keywords

HEAT SHOCK PROTEIN 27; MESSENGER RNA;

ADENOCARCINOMA; ADULT; AGED; ARTICLE; BARRETT ESOPHAGUS; CANCER SUSCEPTIBILITY; ESOPHAGUS; ESOPHAGUS CANCER; ESOPHAGUS MUCOSA; FEMALE; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MALIGNANT TRANSFORMATION; NORTHERN BLOTTING; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA TRANSCRIPTION; SEX DIFFERENCE; SOUTHERN BLOTTING;

ADENOCARCINOMA; AGED; AGED, 80 AND OVER; AMINO ACID SEQUENCE; BARRETT ESOPHAGUS; CELL TRANSFORMATION, NEOPLASTIC; DISEASE SUSCEPTIBILITY; ESOPHAGEAL NEOPLASMS; ESOPHAGUS; ESTRADIOL; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HEAT-SHOCK PROTEINS; HUMANS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; SEX FACTORS;

EID: 0032938932     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6690094     Document Type: Article

References (54)

1. Al-Kasspooles M, Moore JH, Orringer MB and Beer DG (1993) Amplification and overexpression of the EGFR and erbB-2 genes in human esophageal adenocarcinomas Int J Cancer 54: 213-219
2. Ames BN, Shigenaga MK and Hagen TM (1993) Oxidants, antioxidants, and the degenerative diseases of aging. Proc Natl Acad Sci, USA. 90: 7915-7922
3. Arrigo A-P and Welch WJ (1987) Characterization and purification of the small 28,000-Dalton mammalian heat shock protein. J Biol Chem 262: 15359-15369
4. Barrett NR (1950) Chronic peptic ulcer of the oesophagus and 'oesophagitis'. Br J Surg 38: 175-182
5. Barrett NR (1957) The lower esophagus lined by columnar epithelium. Surgery 41: 881-894
6. Blot WJ, Devesa SS, Kneller RW and Fraumeni JF (1991) Rising incidence of adenocarcinoma of the esophagus and gastric cardia. JAMA 265: 1287-1289
7. Bremner CG, Lynch VP, and Ellis FH (1970) Barrett's esophagus: congenital or acquired? An experimental study of esophageal mucosal regeneration in the dog. Surgery 68: 209-216
8. Cameron AJ, Ott BJ and Payne WS (1985) The incidence of adenocarcinoma in columnar-lined (Barrett's) esophagus. N Engl J Med 313: 857-859
9. Ciocca RD, Adams DJ, Edwards DP, Bjercke RJ and McGuire WL (1983) Distribution of an estrogen-induced protein with a molecular weight of 24,000 in normal and malignant human tissues and cells. Cancer Res 43: 1204-1210
10. Dressler LG, Ramzy I, Sledge GW and McGuire WL (1986) A new marker of maturation in the cervix: the estrogen-regulated 24k protein. Obstet Gynecol 68: 825-831
11. Dunn DK, Whelan RDH, Hill B and King RJB (1993) Relationship of HSP27 and oestrogen receptor in hormone sensitive and insensitive cell lines. J Steroid Biochem Mol Biol 46: 469-479
12. Edwards DP, Adams DJ, Savage N and McGuire WL (1980) Estrogen induced synthesis of specific proteins in human breast cancer cells. Biochem Biophys Res Commun 93: 804-812
13. Fiers W (1991) Tumor necrosis factor: characterization at the molecular, cellular and in vivo level. FEBS Lett 285: 199-212
14. Fuqua SAW, Blum-Salingaros M and McGuire WL (1989) Induction of the estrogen-regulated '24K' protein by heat shock. Cancer Res 49: 4126-4129
15. Goldman MC and Beckman RC (1960) Barrett syndrome: case report with discussion about concepts of pathogenesis. Gastroenterology 39: 104-110
16. Hamilton SR (1992) Oesophagitis. In Pathology of the Gastrointestinal Tract. Ming S-C and Goldman H (eds), pp. 381-438. WB Saunders: Philadelphia
17. Hanash SM, Baier LJ, McCurry L and Schwartz SA (1986) Lineage-related polypeptide markers in acute lymphoblastic leukemia detected by two-dimensional gel electrophoresis. Proc Natl Acad Sci USA 83: 807-811
18. Hanash SM, Kuick R, Nichols D and Stoolman L (1988) Quantitative analysis of a new marker for common acute lymphoblastic leukemia detected by two-dimensional electrophoresis. Dis Markers 6: 209-220
19. Hanson LA, Nuzum EO, Jones BC, Malkinson AM and Beer DG (1991) Expression of the glucocorticoid receptor and K-ras genes in urethan-induced mouse lung tumors and transformed cell lines. Exp Lung Res 17: 371-387
20. Hesketh PJ, Clapp RW, Doos WG and Spechler SJ (1989) The increasing frequency of adenocarcinoma of the esophagus. Cancer 64: 526-530
21. Hickey E, Brandon SE, Sadis S, Smale G and Weber LA (1986) Molecular cloning of sequences encoding the human heat-shock proteins and their expression during hyperthermia. Gene 43: 147-154
22. Hinder RA and Stein HJ (1991) Oxygen-derived free radicals. Arch Surg 126: 104-105
23. 1 27,000 heat shock protein. Cancer Res 51: 5245-5252
24. Hout J, Houle F, Spitz DR and Landry J (1996) Hsp27 phosphorylation-mediated resistance against actin fragmentation and cell death induced by oxidative stress. Cancer Res 56: 273-279
25. Kuick RD, Hanash SM, Chu EHY and Strahler JR (1987) A comparison of some adjustment techniques for use with quantitative spot data from two-dimensional gels. Electrophoresis 8: 199-204
26. Landry J, Chretien P, Lambert H, Hickey E and Weber LA (1989) Heat shock resistance conferred by expression of the human hsp27 gene in rodent cells. J Cell Biol 109: 7-15
27. Landry J, Chretien P, Laszlo A and Lambert H (1991) Phosphorylation of Hsp27 during development and decay of thermotolerance in Chinese hamster cells. J Cell Physiol 147: 93-101
28. Landry J, Lambert H, Zhou M, Lavoie JN, Hickey E, Weber LA and Anderson CW (1992) Human Hsp27 is phosphorylated at serines 78 and 82 by heat shock and mitogen-activated kinases that recognize the same amino acid motif as S6 kinase II. J Biol Chem 267: 794-803
29. Lavoie JN, Lambert H, Hickey E, Weber LA and Landry J (1995) Modulation of cellular thermoresistance and actin filament stability accompanies phosphorylation-induced changes in the oligomeric structure of heat shock protein 27. Mol Cell Biol 15: 505-516
30. McBride TJ, Preston BD and Loeb LA (1991) Mutagenic spectrum resulting from DNA damage by oxygen radicals. Biochemistry 30: 207-213
31. Mehlen P, Mehlen A, Guillet D, Preville X and Arrigo A-P (1995a) Tumor necrosis factor-α induces changes in the phosphorylation, cellular localization, and oligomerization of human hsp27, a stress protein that confers cellular resistance to this cytokine. J Cell Biochem 58: 248-259
32. Mehlen P, Preville X, Chareyron P, Briolay J, Klemenz R and Arrigo A-P (1995b) Constitutive expression of human hsp27, Drosophila hsp27, or human aB-crystallin confers resistance to TNF-and oxidative stress-induced cytotoxicity in stably transfected murine L929 fibroblasts. J Immunol 154: 363-374
33. Mehlen P, Kretz-Remy C, Preville X and Arrigo A-P (1996) Human hsp27, Drosophila hsp27 and human αB-crystallin expression-mediated increase in glutathione is essential for the protective activity of these proteins against TNFα-induced cell death. EMBO J 15: 2695-2706
34. Moscow JA, Fairchild CR, Madden MJ, Ransom DT, Wicand HS, O'Brien EE, Poplack DG, Cossman J, Myers CE and Cowan KH (1989) Expression of anionic glutathione-S-transferase and p-glycoprotein genes in human tissues and tumors. Cancer Res 49: 1422-1428
35. Naef AP, Savary M and Ozzello L (1975) Columnar-lined lower esophagus: an acquired lesion with malignant predisposition. J Thorac Cardiovasc Surg 70: 826-835
36. Olyaee M, Sontag S, Salman W, Schnell T, Mobarhan S, Eiznhamer D and Keshavarzian A (1995) Mucosal reactive oxygen species production in oesophagitis and Barrett's oesophagus. Gut 37: 168-173
37. Rachwal WJ, Bongiorno PF, Orringer MB, Whyte RI, Ethier SP and Beer DG (1995) Expression and activation of erbB-2 and epidermal growth factor receptor in lung adenocarcinomas. Br J Cancer 72: 56-64
38. Reed PI and Johnson BJ (1993) The changing incidence of oesophageal cancer. Endoscopy 25: 606-608
39. Richards EH, Hickey E, Weber L and Masters JRW (1996) Effect of overexpression of the small heat shock protein HSP27 on the heat and drug sensitivities of human testis tumor cells. Cancer Res 56: 2446-2451
40. Schnell T, Sontag S, Wanner J, Chintam R, Chejfec G, O'Connell S and Moroni B (1985) Endoscopic screening for Barrett's esophagus (BE), esophageal adenocarcinoma (AdCa) and other mucosal changes in ambulatory subjects with symptomatic gastroesophageal reflux (GER). Gastroenterology 88: 1576
41. Skinner DB, Walther BC, Riddell RH, Schmidt H, Iascone C and Demeester TR (1983) Barrett's esophagus. Comparison of benign and malignant cases. Ann Surg 198: 554-566
42. Spechler SJ, Robbins AH, Rubins HB, Vincent ME, Heeren T, Doos WG, Colton T and Schimmel EM (1984) Adenocarcinoma and Barrett's esophagus: an overrated risk? Gastroenterology 87: 927-933
43. Stoner GD, Kaighn ME, Reddel RR, Resau JH, Bowman D, Naito Z, Matsukura N, You M, Galati AJ and Harris CC (1991) Establishment and characterization of SV40 T-antigen immortalized human esophageal epithelia cells. Cancer Res 51: 365-371
44. Strahler JR, Kuick R, Eckerskorn C, Lottspeich F, Richardson BC, Fox DA, Stoolman LM, Hanson CA, Nichols D, Tueche HJ and Hanash SM (1990) Identification of two related markers for common acute lymphoblastic leukemia as heat shock proteins. J Clin Invest 85: 200-207
45. Trautinger F, Kindas-Mugge I, Dekrout B, Knobler RM and Metze D (1995) Expression of the 27-kDa heat shock protein in human epidermis and in epidermal neoplasms: an immunohistological study. Br J Dermatol 133: 194-202
46. Trush MA and Kensler TW (1991) An overview of the relationship between oxidative stress and chemical carcinogenesis. Free Radical Biol Med 10: 201-209
47. Van Der Veen AH, Dees J, Blankensteijn JD and Van Blankenstein M (1989) Adenocarcinoma in Barrett's oesophagus: an overrated risk. Gut 30: 14-18
48. Welch WJ (1985) Phorbol ester, calcium ionophore, or serum added to quiescent rat embryo fibroblast cells all result in the elevated phosphorylation of two 28,000-Dalton mammalian stress proteins. J Biol Chem 260: 3058-3062
49. Wetscher GJ, Hinder PR, Bagchi D, Perdikis G, Redmond EJ, Glaser K, Adrian TE and Hinder RA (1995a) Free radical scavengers prevent reflux esophagitis in rats. Dig Dis Sci 40: 1292-1296
50. Wetscher GJ, Hinder RA, Bagchi D, Hinder PR, Bagchi M, Perdikis G and McGinn T (1995b) Reflux esophagitis in humans is mediated by oxygen-derived free radicals. Am J Surg 170: 552-557
51. Wetscher GJ, Perdikis G, Kretchmar DH, Stinson RG, Bagchi D, Redmond EJ, Adrian TE and Hinder RA (1995c) Esophagitis in Sprague-Dawley rats is mediated by free radicals. Dig Dis Sci 40: 1297-1305
52. Wheater PR, Burkitt HG and Daniels VG (1987) Functional Histology: a Text and Colour Atlas, pp. 64-78. Churchill Livingstone: New York
53. Winters C, Spurling TJ, Chobanian SJ, Curtis DJ, Esposito RL, Hacker JF, Johnson DA, Cruess DF, Cotelingam JD, Gurney MS and Cattau EL (1987) Barrett's esophagus: a prevalent, occult complication of gastroesophageal reflux disease. Gastroenterology 92: 118-124
54. Wu W and Welsh MJ (1996) Expression of the 25-kDa heat-shock protein (HSP27) correlates with resistance to the toxicity of cadmium chloride, mercuric chloride, cis-platinum(II)-diammine dichloride, or sodium arsenite in mouse embryonic stem cells transfected with sense or antisense HSP27 cDNA. Toxicol Appl Pharmacol 141: 330-339