Signaling and metabolic predispositions linked to the colorectal cancer;Signalisation et prédispositions métaboliques liées au cancer colorectal

Medecine/Sciences

Volumn 27, Issue 5, 2011, Pages 514-520

  Olivier, Stéphanie ^a   Mir, Anne Marie ^a   Michalski, Jean Claude ^a   Lefebvre, Tony ^a  

^a UNIVERSITÉ DES SCIENCES ET TECHNOLOGIES DE LILLE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CTNNB1 PROTEIN, HUMAN; N ACETYLGLUCOSAMINE; PROTEIN TYROSINE KINASE; WNT PROTEIN;

ADENOCARCINOMA; BIOLOGICAL MODEL; COLORECTAL TUMOR; DIET; DISEASE COURSE; DISEASE PREDISPOSITION; ENERGY METABOLISM; GENETICS; GLYCOSYLATION; HUMAN; INSULIN RESISTANCE; INTESTINE MUCOSA; METABOLIC SYNDROME X; METABOLISM; ONCOGENE; PATHOLOGY; PHYSIOLOGY; PROTEIN PROCESSING; REVIEW; RISK FACTOR; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR GENE;

ACETYLGLUCOSAMINE; ADENOCARCINOMA; BETA CATENIN; COLORECTAL NEOPLASMS; DIET; DISEASE PROGRESSION; DISEASE SUSCEPTIBILITY; ENERGY METABOLISM; GENES, P53; GENES, TUMOR SUPPRESSOR; GLYCOSYLATION; HUMANS; INSULIN RESISTANCE; INTESTINAL MUCOSA; METABOLIC SYNDROME X; MODELS, BIOLOGICAL; ONCOGENES; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECEPTOR PROTEIN-TYROSINE KINASES; RISK FACTORS; SIGNAL TRANSDUCTION; WNT PROTEINS;

EID: 79958697701     PISSN: 07670974     EISSN: None     Source Type: Journal    
DOI: 10.1051/medsci/2011275017     Document Type: Review

References (33)

1. Fearon ER, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell 1990; 61: 759-67.
2. Markowitz SD, Bertagnolli MM. Molecular origins of cancer : Molecular basis of colorectal cancer. N Engl J Med 2009; 361: 2449-60.
3. Reya T, Clevers H. Wnt signalling in stem cells and cancer. Nature 2005; 434 : 843-50. (Pubitemid 40558990)
4. Yang J, Zhang W, Evans PM, et al. Adenomatous polyposis coli (APC) differentially regulates beta-catenin phosphorylation and ubiquitination in colon cancer cells. J Biol Chem 2006 ; 281 : 17751-7.
5. McCubrey JA, Steelman LS, Chappell WH, et al. Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance. Biochim Biophys Acta 2007 ; 1773:1263-84.
6. Bos JL, Fearon ER, Hamilton SR, Vogelstein B. Prevalence of ras gene mutations in human colorectal cancers. Nature 1987; 327 : 293-7. (Pubitemid 17075079)
7. Davies H, Bignell GR, Cox C, et al. Mutations of the BRAF gene in human cancer. Nature 2002; 417 : 949-54. (Pubitemid 34716871)
8. Chang F, Lee JT, Navolanic PM, et al. Involvement of Pl3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation : a target for cancer chemotherapy. Leukemia 2003; 17: 590-603. (Pubitemid 36395654)
9. Samuels y, Wang Z, Bardelli A, et al. High frequency of mutations of the PIK3CA gene in human cancers. Science 2004; 304 : 554.
10. Parsons DW, Wang TL, Samuels y, et al. Colorectal cancer : mutations in a signalling pathway. Mature 2005; 436 : 792. (Pubitemid 41160630)
11. Xu y, Pasche B. TGF-beta signaling alterations and susceptibility to colorectal cancer. Hum Mol Genet 2007 ; 16 no special 1 : R14-20.
12. Biswas S, Trobridge P, Romero-Gallo J, et al. Mutational inactivation of TGFBR2 in microsatellite unstable colon cancer arises from the cooperation of genomic instability and the clonal outgrowth of transforming growth factor beta resistant cells. Genes Chromosomes Cancer 2008; 47 : 95-106.
13. Tokogi y, Kohmura H, Futamura M, et al. Somatic alterations of the DPC4 gene in human colorectal cancers in vivo. Gastroenterology 1996; 111 : 1369-72.
14. Papazoglu C, Mills AA. p53 : at the crossroad between cancer and ageing. J Pathol 2007; 211:124-33.
15. Baker SJ, Markowitz S, Fearon ER, et al. Suppression of human colorectal carcinoma cell growth by wild-type p53. Science 1990; 249 : 912-5.
16. Hector S, Prehn JH. Apoptosis signaling proteins as prognostic biomarkers in colorectal cancer : a review. Biochim Biophys Acta 2009 ; 1795:117-29.
17. Gnagnarella P, Gandini S, La Vecchia C, Maisonneuve P. Glycemic index, glycemic load, and cancer risk : a meta-analysis. Am J Clin Nutr 2008; 87 : 1793-801. (Pubitemid 351872644)
18. Key TJ, Spencer EA. Carbohydrates and cancer : an overview of the epidemiological evidence. Eur J Clin Nutr 2007; 61 (suppl 1) : S112-21. (Pubitemid 350104365)
19. Pais R, Silaghi H, Silaghi AC, et al. Metabolic syndrome and risk of subsequent colorectal cancer. Worfd; Gastroenterol 2009; 15 : 5141-8.
20. yam D, Fink A, Mashiah A, Ben-Hur E. Hyperinsulinemia in colon, stomach and breast cancer patients. Cancer Lett 1996; 104 : 129-32.
21. Khaw KT, Wareham N, Bingham S, et al. Preliminary communication: glycated hemoglobin, diabetes, and incident colorectal cancer in men and women : a prospective analysis from the European prospective investigation into cancer-Norfolk study. Cancer Epidemiol Biomarkers Prev 2004;13:915-9. (Pubitemid 38756700)
22. Giovannucci E. Insulin, insulin-like growth factors and colon cancer : a review of the evidence. J Nutr 2001; 131:3109S-20S. (Pubitemid 33070788)
23. Issad T. O-GIcNAc glycosylation and regulation of cell signaling. Med Sci (Paris) 2010; 26 : 753-9.
24. Yang X, Ongusaha PP, Miles PD, et al. Phosphoinositide signalling links O-GIcNAc transferase to insulin resistance. Nature 2008; 451: 964-9. (Pubitemid 351301737)
25. Chou TY, Hart GW, Dang CV. c-Myc is glycosylated at threonine 58, a known phosphorylation site and a mutational hot spot in lymphomas. J Biol Chem 1995;270:18961-5.
26. Yang WH, Kim JE, Nam HW, et al. Modification of p53 with O-linked N-acetylglucosamine regulates p53 activity and stability. Nat Cell Biol 2006;8:1074-83. (Pubitemid 44473602)
27. Dehennaut V, Slomianny MC, Page A, et al. Identification of structural and functional O-linked N-acetylglucosamine-bearing proteins in Xenopus laevis oocyte. Mol Cell Pnteomics 2008; 7:2229-45.
28. Dehennaut V, Hanoulle X, Bodart JF, et at. Microinjection of recombinant O-GlcNAc transferase potentiates Xenopus oocytes M-phase entry. Biochem Biophys Res Commun 2008; 369 : 539-46.
29. Lefebvre T, Baert F, Bodart JF, et al. Modulation of O-GlcNAc glycosylate during Xenopus oocyte maturation. J Cell Biochem 2004; 93: 999-1010. (Pubitemid 44264153)
30. Hatsell S, Medina L, Merola J, et al. Plakoglobin is O-glycosylated close to the N-terminal destruction box. J Biol Chem 2003; 278 : 37745-52. (Pubitemid 37175300)
31. Weither A, Johnstone E, Swanton C, et al. Genetic prognostic and predictive markers in colorectal cancer. Nat Rev Cancer 2009; 9 : 489-99.
32. Evaluation des risques et perspectives thérapeutiques en oncologie colorectale. Med Sci (Paris) 2009; 25 (hs1) : 1-56.
33. Bodmer A, Goetsch L, Favet L, et al. Anticorps et tumeurs solides. Cibles établies et pistes prometteuse. Med Sci (Paris) 2009;25:1090-8.