Physiology of the human corneal endothelium new insights from electrophysiological investigations;Physiologie des humanen Hornhautendothels neue Erkenntnisse durch elektrophysiologische Untersuchungen

Klinische Monatsblatter fur Augenheilkunde

Volumn 228, Issue 6, 2011, Pages 520-524

  Mergler, S ^a   Pleyer, U ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

cell vitality; human corneal endothelium; in vitro electrophysiology; ion channels

Indexed keywords

CALCIUM; PHEROMONE DERIVATIVE; POLYCYSTIN;

ARTICLE; CELL MEMBRANE; CELL STRUCTURE; CORNEA ENDOTHELIUM; ELECTROPHYSIOLOGY; ENDOTHELIUM CELL; FUNCTION TEST; HUMAN; HUMAN CELL; OSMOLARITY; PAIN; PATCH CLAMP; SENSITIVITY ANALYSIS; TASTE; TEMPERATURE; VISUAL SYSTEM FUNCTION;

ANIMALS; ENDOTHELIAL CELLS; EPITHELIUM, CORNEAL; HUMANS; MODELS, BIOLOGICAL; PATCH-CLAMP TECHNIQUES; TRANSIENT RECEPTOR POTENTIAL CHANNELS;

EID: 79958289955     PISSN: 00232165     EISSN: 14393999     Source Type: Journal    
DOI: 10.1055/s-0031-1273254     Document Type: Article

References (48)

1. Waring III G O., Bourne W M., Edelhauser H F. et al. The corneal endothelium. Normal and pathologic structure and function. Ophthalmology 1982 89 531-590 (Pubitemid 12085989)
2. Joyce N C. Proliferative capacity of the corneal endothelium. Prog Retin Eye Res 2003 22 359-389 (Pubitemid 38352553)
3. Bell K D., Campbell R J., Bourne W M. Pathology of late endothelial failure: late endothelial failure of penetrating keratoplasty: study with light and electron microscopy. Cornea 2000 19 40-46 (Pubitemid 30007743)
4. Ing J J., Ing H H., Nelson L R. et al. Ten-year postoperative results of penetrating keratoplasty. Ophthalmology 1998 105 1855-1865 (Pubitemid 28509725)
5. Bourne W M. Corneal endothelium past, present, and future. Eye Contact Lens 2010 36 310-314
6. Armitage W J., Dick A D., Bourne W M. Predicting endothelial cell loss and long-term corneal graft survival. Invest Ophthalmol Vis Sci 2003 44 3326-3331 (Pubitemid 36909766)
7. Barcia R N., Dana M R., Kazlauskas A. Corneal graft rejection is accompanied by apoptosis of the endothelium and is prevented by gene therapy with bcl-xL. Am J Transplant 2007 7 2082-2089 (Pubitemid 47247044)
8. Fuchsluger T A., Jurkunas U, Kazlauskas A et al. Corneal Endothelial Cells Are Protected from Apoptosis by Gene Therapy. Hum Gene Ther 2010 (Epub ahead of print)
9. Lindstrom R L. Advances in corneal preservation. Trans Am Ophthalmol Soc 1990 88 555-648
10. Borenfreund E, Puerner J A. Toxicity determined in vitro by morphological alterations and neutral red absorption. Toxicol Lett 1985 24 119-124 (Pubitemid 15103513)
11. Bednarz J, Doubilei V, Wollnik P C. et al. Effect of three different media on serum free culture of donor corneas and isolated human corneal endothelial cells. Br J Ophthalmol 2001 85 1416-1420 (Pubitemid 34032904)
12. Engelmann K, Drexler D, Böhnke M. Transplantation of adult human or porcine corneal endothelial cells onto human recipients in vitro. Part I: Cell culturing and transplantation procedure. Cornea 1999 18 199-206 (Pubitemid 29159264)
13. Melles G R., Lander F, Rietveld F J. Transplantation of Descemets membrane carrying viable endothelium through a small scleral incision. Cornea 2002 21 415-418 (Pubitemid 34450480)
14. Moller-Pedersen T, Hartmann U, Moller H J. et al. Evaluation of potential organ culture media for eye banking using human donor corneas. Br J Ophthalmol 2001 85 1075-1079 (Pubitemid 32842460)
15. Ramsey I S., Delling M, Clapham D E. An introduction to TRP channels. Annu Rev Physiol 2006 68 619-647
16. Rae J L., Watsky M A. Ionic channels in corneal endothelium. Am J Physiol 1996 270 C975-C989
17. Watsky M A., Cooper K, Rae J L. Sodium channels in ocular epithelia. Pflugers Archive 1991 419 454-459
18. Watsky M A., Cooper K, Rae J L. Transient outwardly rectifying potassium channel in the rabbit corneal endothelium. J Membr Biol 1992 128 123-132
19. Rae J L., Shepard A R. Kir2.1 Potassium channels and corneal epithelia. Curr Eye Res 2000 20 144-152 (Pubitemid 30099168)
20. Rae J L., Dewey J, Cooper K. Properties of single potassium-selective ionic channels from the apical membrane of rabbit corneal endothelium. Exp Eye Res 1989 49 591-609 (Pubitemid 19264422)
21. Mergler S, Dannowski H, Bednarz J et al. Calcium influx induced by activation of receptor tyrosine kinases in SV 40-transfected human corneal endothelial cells. Exp Eye Res 2003 77 485-495 (Pubitemid 37040846)
22. Mergler S, Pleyer U, Reinach P et al. EGF suppresses hydrogen peroxide induced Ca2 + influx by inhibiting L-type channel activity in cultured human corneal endothelial cells. Exp Eye Res 2005 80 285-293
23. Mergler S, Pleyer U. The human corneal endothelium: New insights into electrophysiology and ion channels. Prog Retin Eye Res 2007 26 359-378 (Pubitemid 46766642)
24. Mergler S, Valtink M, Coulson-Thomas V J. et al. TRPV channels mediate temperature-sensing in human corneal endothelial cells. Exp Eye Res 2010 90 758-770
25. Rae J L., Dewey J, Cooper K et al. A non-selective cation channel in rabbit corneal endothelium activated by internal calcium and inhibited by internal ATP. Exp Eye Res 1990 50 373-384 (Pubitemid 20134573)
26. Zhang F, Yang H, Wang Z et al. Transient receptor potential vanilloid 1 activation induces inflammatory cytokine release in corneal epithelium through MAPK signaling. J Cell Physiol 2007 213 730-739 (Pubitemid 350058266)
27. Mergler S, Garreis F, Sahlmüller M et al. Thermosensitive transient receptor potential channels (thermo-TRPs) in human corneal epithelial cells. J Cell Physiol 2010; (Epub ahead of print)
28. Chuang H H., Neuhausser W M., Julius D. The super-cooling agent icilin reveals a mechanism of coincidence detection by a temperature-sensitive TRP channel. Neuron 2004 43 859-869 (Pubitemid 39215016)
29. Voets T, Droogmans G, Wissenbach U et al. The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels. Nature 2004 430 748-754 (Pubitemid 39071340)
30. Parra A, Madrid R, Echevarria D et al. Ocular surface wetness is regulated by TRPM8-dependent cold thermoreceptors of the cornea. Nat Med 2010 16 1396-1399
31. Chow J, Norng M, Zhang J et al. TRPV6 mediates capsaicin-induced apoptosis in gastric cancer cells Mechanisms behind a possible new hot cancer treatment. Biochim Biophys Acta 2007 1773 565-576 (Pubitemid 46441507)
32. Sappington R M., Sidorova T, Long D J. et al. TRPV1: Contribution to Retinal Ganglion Cell Apoptosis and Increased Intracellular Ca2 + with Exposure to Hydrostatic Pressure. Invest Ophthalmol Vis Sci 2009 50 717-728
33. Yao X, Garland C J. Recent developments in vascular endothelial cell transient receptor potential channels. Circ Res 2005 97 853-863 (Pubitemid 41552670)
34. Zhang W, Chu X, Tong Q et al. A novel TRPM2 isoform inhibits calcium influx and susceptibility to cell death. J Biol Chem 2003 278 16222-16229 (Pubitemid 36799746)
35. Rusznak Z, Harasztosi C, Stanfield P R. et al. An improved cell isolation technique for studying intracellular Ca(2 +) homeostasis in neurones of the cochlear nucleus. Brain Res Brain Res Protoc 2001 7 68-75 (Pubitemid 32241230)
36. Li Q J., Ashraf M F., Shen D F. et al. The role of apoptosis in the pathogenesis of Fuchs endothelial dystrophy of the cornea. Arch Ophthalmol 2001 119 1597-1604 (Pubitemid 33035700)
37. Lu L. Stress-induced corneal epithelial apoptosis mediated by K(+) channel activation. Prog Retin Eye Res 2006 25 515-538 (Pubitemid 44755130)
38. Banan A, Fields J Z., Zhang Y et al. Key role of PKC and Ca2 + in EGF protection of microtubules and intestinal barrier against oxidants. Am J Physiol Gastrointest Liver Physiol 2001 280 G828-G843
39. Barisani-Asenbauer T, Kaminski S, Schuster E et al. Impact of growth factors on morphometric corneal endothelial cell parameters and cell density in culture-preserved human corneas. Cornea 1997 16 537-540 (Pubitemid 27381605)
40. Rieck P, Oliver L, Engelmann K et al. The role of exogenous/endogenous basic fibroblast growth factor (FGF2) and transforming growth factor beta (TGF beta-1) on human corneal endothelial cells proliferation in vitro. Exp Cell Res 1995 220 36-46
41. Rieck P W., Gigon M, Jaroszewski J et al. Increased endothelial survival of organ-cultured corneas stored in FGF-2-supplemented serum-free medium. Invest Ophthalmol Vis Sci 2003 44 3826-3832 (Pubitemid 37047952)
42. Mergler S, Steinhausen K, Wiederholt M et al. Altered regulation of L-type channels by protein kinase C and protein tyrosine kinases as a pathophysiologic effect in retinal degeneration. FASEB J 1998 12 1125-1134 (Pubitemid 28418942)
43. Akanda N, Elinder F. Biophysical properties of the apoptosis-inducing plasma membrane VDAC. Biophys J 2006 90 4405-4417 (Pubitemid 43830887)
44. Nagy P, Panyi G, Jenei A et al. Ion-channel activities regulate transmembrane signaling in thymocyte apoptosis and T-cell activation. Immunol Lett 1995 44 91-95
45. Parekh A B., Penner R. Store depletion and calcium influx. Physiol Rev 1997 77 901-930 (Pubitemid 27459576)
46. Skryma R, Mariot P, Bourhis X L. et al. Store depletion and store-operated Ca2 + current in human prostate cancer LNCaP cells: involvement in apoptosis. J Physiol 2000 527 Pt 1 71-83 (Pubitemid 30649585)
47. Kruse F E., Tseng S C. Proliferative and differentiative response of corneal and limbal epithelium to extracellular calcium in serum-free clonal cultures. J Cell Physiol 1992 151 347-360
48. Chvatchko Y, Valera S, Aubry J P. et al. The involvement of an ATP-gated ion channel, P(2X1), in thymocyte apoptosis. Immunity 1996 5 275-283 (Pubitemid 26341370)