MRI artifacts in human brain tissue after prolonged formalin storage

Magnetic Resonance in Medicine

Volumn 65, Issue 6, 2011, Pages 1750-1758

  Van Duijn, Sara ^a   Nabuurs, Rob J A ^a   Van Rooden, Sanneke ^a   Maat Schieman, Marion L C ^a   Van Duinen, Sjoerd G ^a   Van Buchem, Mark A ^a   Van Der Weerd, Louise ^a   Natté, Remco ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

ex vivo; formalin; MRI

Indexed keywords

BRAIN; DEPOSITS; FORMALDEHYDE; GLYCOPROTEINS; MAGNETIC RESONANCE IMAGING; PATHOLOGY; SCANNING;

AMYLOID DEPOSITS; BRAIN PATHOLOGIES; EX-VIVO; HIGH RESOLUTION; PRESENCE/ABSENCE; TISSUE PRESERVATION; TISSUE REACTIONS; TRANSVERSE RELAXATION TIME;

TISSUE;

AMYLOID BETA PROTEIN; FORMALDEHYDE;

ALZHEIMER DISEASE; ARTICLE; BRAIN CORTEX; BRAIN TISSUE; CEREBROVASCULAR DISEASE; CONTROLLED STUDY; DOWN SYNDROME; ELECTRON MICROSCOPY; HEREDITARY CEREBRAL HEMORRHAGE WITH AMYLOID DUTCH TYPE; HUMAN; IMAGE QUALITY; NUCLEAR MAGNETIC RESONANCE IMAGING; SPORADIC CEREBRAL AMYLOID ANGIOPATHY; TISSUE FIXATION;

EID: 79958287777     PISSN: 07403194     EISSN: 15222594     Source Type: Journal    
DOI: 10.1002/mrm.22758     Document Type: Article

References (31)

1. Benveniste H, Einstein G, Kim KR, Hulette C, Johnson GA,. Detection of neuritic plaques in Alzheimer's disease by magnetic resonance microscopy. Proc Natl Acad Sci USA 1999; 96: 14079-14084.
2. Bobinski M, De Leon MJ, Wegiel J, Desanti S, Convit A, Saint Louis LA, Rusinek H, Wisniewski HM,. The histological validation of post mortem magnetic resonance imaging-determined hippocampal volume in Alzheimer's disease. Neuroscience 2000; 95: 721-725.
3. Bronge L, Bogdanovic N, Wahlund LO,. Postmortem MRI and histopathology of white matter changes in Alzheimer brains. A quantitative, comparative study. Dement Geriatr Cogn Disord 2002; 13: 205-212. (Pubitemid 34507605)
4. Englund E, Sjobeck M, Brockstedt S, Latt J, Larsson EM,. Diffusion tensor MRI post mortem demonstrated cerebral white matter pathology. J Neurol 2004; 251: 350-352. (Pubitemid 38387157)
5. Fernando MS, O'Brien JT, Perry RH, English P, Forster G, Mcmeekin W, Slade JY, Golkhar A, Matthews FE, Barber R, Kalaria RN, Ince PG,. Comparison of the pathology of cerebral white matter with post-mortem magnetic resonance imaging (MRI) in the elderly brain. Neuropathol Appl Neurobiol 2004; 30: 385-395. (Pubitemid 39120300)
6. Geurts JJ, Bo L, Pouwels PJ, Castelijns JA, Polman CH, Barkhof F,. Cortical lesions in multiple sclerosis: combined postmortem MR imaging and histopathology. AJNR Am J Neuroradiol 2005; 26: 572-577. (Pubitemid 43085960)
7. Gouw AA, Seewann A, Vrenken H, Van Der Flier WM, Rozemuller JM, Barkhof F, Scheltens P, Geurts JJ,. Heterogeneity of white matter hyperintensities in Alzheimer's disease: post-mortem quantitative MRI and neuropathology. Brain 2008; 131 (pt 12): 3286-3298.
8. House MJ, St Pierre TG, Kowdley KV, Montine T, Connor J, Beard J, Berger J, Siddaiah N, Shankland E, Jin LW,. Correlation of proton transverse relaxation rates (R2) with iron concentrations in postmortem brain tissue from Alzheimer's disease patients. Magn Reson Med 2007; 57: 172-180. (Pubitemid 46067947)
9. Kangarlu A, Bourekas EC, Ray-Chaudhury A, Rammohan KW,. Cerebral cortical lesions in multiple sclerosis detected by MR imaging at 8 Tesla. AJNR Am J Neuroradiol 2007; 28: 262-266. (Pubitemid 46281042)
10. Larsson EM, Englund E, Sjobeck M, Latt J, Brockstedt S,. MRI with diffusion tensor imaging post-mortem at 3.0 T in a patient with frontotemporal dementia. Dement Geriatr Cogn Disord 2004; 17: 316-319. (Pubitemid 38721149)
11. Schmierer K, Parkes HG, So PW, An SF, Brandner S, Ordidge RJ, Yousry TA, Miller DH,. High field (9.4 Tesla) magnetic resonance imaging of cortical grey matter lesions in multiple sclerosis. Brain 2010; 133 (pt 3): 858-867.
12. Van Rooden S, Maat-Schieman ML, Nabuurs RJ, Van Der Weerd L, Van Duijn S, Van Duinen SG, Natte R, Van Buchem MA, Van Der Grond J,. Cerebral amyloidosis: postmortem detection with human 7.0-T MR imaging system. Radiology 2009; 253: 788-796.
13. Blamire AM, Rowe JG, Styles P, Mcdonald B,. Optimising imaging parameters for post mortem MR imaging of the human brain. Acta Radiol 1999; 40: 593-597. (Pubitemid 129567275)
14. 2 relaxation times during formaldehyde fixation. Magn Reson Med 2009; 61: 810-818.
15. Pfefferbaum A, Sullivan EV, Adalsteinsson E, Garrick T, Harper C,. Postmortem MR Imaging of formalin-fixed human brain. Neuroimage 2004; 21: 1585-1595. (Pubitemid 38446582)
16. Shepherd TM, Thelwall PE, Stanisz GJ, Blackband SJ,. Aldehyde fixative solutions alter the water relaxation and diffusion properties of nervous tissue. Magn Reson Med 2009; 62: 26-34.
17. Shepherd TM, Flint JJ, Thelwall PE, Stanisz GJ, Mareci TH, Yachnis AT, Blackband SJ,. Postmortem interval alters the water relaxation and diffusion properties of rat nervous tissuea-implications for MRI studies of human autopsy samples. Neuroimage 2009; 44: 820-826.
18. Tovi M, Ericsson A,. Measurements of T1 and T2 over time in formalin-fixed human whole-brain specimens. Acta Radiol 1992; 33: 400-404.
19. Yong-Hing CJ, Obenaus A, Stryker R, Tong K, Sarty GE,. Magnetic resonance imaging and mathematical modeling of progressive formalin fixation of the human brain. Magn Reson Med 2005; 54: 324-332. (Pubitemid 41033549)
20. Nagara H, Inoue T, Koga T, Kitaguchi T, Tateishi J, Goto I,. Formalin fixed brains are useful for magnetic resonance imaging (MRI) study. J Neurol Sci 1987; 81: 67-77. (Pubitemid 17140516)
21. D'Arceuil HE, Westmoreland S, De Crespigny AJ,. An approach to high resolution diffusion tensor imaging in fixed primate brain. Neuroimage 2007; 35: 553-565. (Pubitemid 46402978)
22. Metz B, Kersten GF, Hoogerhout P, Brugghe HF, Timmermans HA, De JA, Meiring H, Ten HJ, Hennink WE, Crommelin DJ, Jiskoot W,. Identification of formaldehyde-induced modifications in proteins: reactions with model peptides. J Biol Chem 2004; 279: 6235-6243. (Pubitemid 38248756)
23. Puchtler H, Meloan SN,. On The chemistry of formaldehyde fixation and its effects on immunohistochemical reactions. Histochemistry 1985; 82: 201-204. (Pubitemid 15114056)
24. Levine SM,. Oligodendrocytes and myelin sheaths in normal, quaking and shiverer brains are enriched in iron. J Neurosci Res 1991; 29: 413-419.
25. Smith MA, Harris PL, Sayre LM, Perry G,. Iron accumulation in Alzheimer Disease Is a source of redox-generated free radicals. Proc Natl Acad Sci USA 1997; 94: 9866-9868. (Pubitemid 27408156)
26. Natte R, Maat-Schieman ML, Haan J, Bornebroek M, Roos RA, Van Duinen SG,. Dementia in hereditary cerebral hemorrhage with amyloidosis-dutch type is associated with cerebral amyloid angiopathy but is independent of plaques and neurofibrillary tangles. Ann Neurol 2001; 50: 765-772. (Pubitemid 33116136)
27. Viale G, Gambacorta M, Coggi G, Dell'Orto P, Milani M, Doglioni C,. Glial fibrillary acidic protein immunoreactivity in normal and diseased human breast. Virchows Arch A Pathol Anat Histopathol 1991; 418: 339-348.
28. Natte R, Yamaguchi H, Maat-Schieman ML, Prins FA, Neeskens P, Roos RA, Van Duinen SG,. Ultrastructural evidence of early non-fibrillar Abeta42 in the capillary basement membrane of patients with hereditary cerebral hemorrhage with amyloidosis, Dutch type. Acta Neuropathol 1999; 98: 577-582.
29. Matubayasi N, Nakahara M,. Hydrothermal reactions of formaldehyde and formic acid: free-energy analysis of equilibrium. J Chem Phys 2005; 122: 074509.
30. Schrag M, Dickson A, Jiffry A, Kirsch D, Vinters HV, Kirsch W,. The effect of formalin fixation on the levels of brain transition metals in archived samples. Biometals 2010; 23: 1123-1127.
31. Greenberg SM, Vernooij MW, Cordonnier C, Viswanathan A, Al-Shahi SR, Warach S, Launer LJ, Van Buchem MA, Breteler MM,. Cerebral microbleeds: a guide to detection and interpretation. Lancet Neurol 2009; 8: 165-174.