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Volumn 46, Issue 8, 2011, Pages 3218-3226
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Design, synthesis, and antiproliferative activity of new 1H-pyrrolo[3,2-c]pyridine derivatives against melanoma cell lines
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Author keywords
A375P; Antiproliferative activity; Diarylamide; Diarylurea; Melanoma; Pyrrolo 3,2 c pyridine
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Indexed keywords
1 [3,5 BIS(TRIFLUOROMETHYL)PHENYL] 3 [4 (4 BENZAMIDO 1H PYRROLO[3,2 C]PYRIDIM 1 YL]PHENYL]UREA;
1 [4 (4 BENZAMIDO 1H PYRROLO[3,2 C]PYRIDIN 1 YL]PHENYL] 3 (3,4 DICHLORO PHENYL)UREA;
1 [4 (4 BENZAMIDO 1H PYRROLO[3,2-C]PYRIDIN 1 YL)PHENYL] 3 [4 [(4 ETHYL-PIPERAZIN 1 YL)METHYL] 3 TRIFLUOROMETHYLPHENYL]UREA;
1 [4 [4 BENZAMIDO 1H PYRROLO[3,2 C]PYRIDIM 1 YL] 3 METHYLPHENYL) 3 (2,3 DICHLOROPHENYL)UREA;
1 [4 [4 BENZAMIDO 1H PYRROLO[3,2 C]PYRIDIM 1 YL]PHENYL] 3 (3 TRIFLUOROMETHYL PHENYL)UREA;
1 [4 [4 BENZAMIDO 1H PYRROLO[3,2 C]PYRIDIM 1 YL]PHENYL] 3 (4 CHLORO 3 TRIFLUOROMETHYLPHENYL)UREA;
N [1 [4 [3 (2,3 DICHLOROPHENYL)UREA]PHENYL] 1H PYRROLO[3,2 C]PYRIDIN 4 YL]BENZAMIDE;
N [4 (4 BENZAMIDO 1H PYRROLO[3,2 C]PYRIDIN 1 YL) 3 METHYLPHENYL] 3 TRIFLUOROMETHY -BENZAMIDE;
N [4 (4 BENZAMIDO 1H PYRROLO[3,2 C]PYRIDIN 1 YL) 3 METHYLPHENYL] 4 CHLORO 3 TRIFLUOROMETHYL BENZAMIDE;
N [4 (4 BENZAMIDO 1H PYRROLO[3,2 C]PYRIDIN 1 YL) 3 METHYLPHENYL] 4 MORPHOLINO 3 TRIFLUOROMETHYL BENZAMIDE;
N [4 (4 BENZAMIDO 1H PYRROLO[3,2 C]PYRIDIN 1 YL) 3 METHYLPHENYL] 5 (2 CHLORO 5 TRIFLUOROMETHYLPHENYL)FURAN 2 CARBOXAMIDE;
N [4 (4 BENZAMIDO 1H PYRROLO[3,2 C]PYRIDIN 1 YL) PHENYL] 3 (4 METHYL 1H IMIDAZOL 1 YL) 5 TRIFLUOROMETHYL BENZAMIDE;
N [4 (4 BENZAMIDO 1H PYRROLO[3,2 C]PYRIDIN 1 YL) PHENYL] 3 MORPHOLINO 3 TRIFLUOROMETHYL BENZAMIDE;
N [4 (4 BENZAMIDO 1H PYRROLO[3,2 C]PYRIDIN 1 YL) PHENYL] 3 TRIFLUOROMETHYL BENZAMIDE;
N [4 (4 BENZAMIDO 1H PYRROLO[3,2 C]PYRIDIN 1 YL) PHENYL] 4 CHLORO 3 TRIFLUOROMETHYL BENZAMIDE;
N [4 (4 BENZAMIDO 1H PYRROLO[3,2 C]PYRIDIN 1 YL) PHENYL] 4 MORPHOLINO 3 TRIFLUOROMETHYL BENZAMIDE;
PYRIDINE DERIVATIVE;
SORAFENIB;
UNCLASSIFIED DRUG;
ARTICLE;
CELL PROLIFERATION;
DRUG DESIGN;
DRUG POTENCY;
DRUG SYNTHESIS;
FIBROBLAST;
HUMAN;
HUMAN CELL;
IC 50;
IN VITRO STUDY;
MELANOMA CELL;
SUBSTITUTION REACTION;
ANIMALS;
ANTINEOPLASTIC AGENTS;
BENZENESULFONATES;
CELL LINE, TUMOR;
CELL PROLIFERATION;
DRUG SCREENING ASSAYS, ANTITUMOR;
HUMANS;
INHIBITORY CONCENTRATION 50;
MELANOMA;
MICE;
PYRIDINES;
PYRROLES;
SKIN NEOPLASMS;
STRUCTURE-ACTIVITY RELATIONSHIP;
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EID: 79958278972
PISSN: 02235234
EISSN: 17683254
Source Type: Journal
DOI: 10.1016/j.ejmech.2011.04.031 Document Type: Article |
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Times cited : (33)
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References (24)
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