Fast analysis of recombinant monoclonal antibodies using IdeS proteolytic digestion and electrospray mass spectrometry

Analytical Biochemistry

Volumn 415, Issue 2, 2011, Pages 212-214

  Chevreux, Guillaume ^a   Tilly, Nolwenn ^a   Bihoreau, Nicolas ^a  

^a LFB Biotechnologies   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; COVALENT BONDS; MASS SPECTROMETRY; MONOCLONAL ANTIBODIES; SULFUR COMPOUNDS;

ELECTROSPRAY MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; MONOCLONAL ANTIBODIES (MABS); POLYPEPTIDE CHAIN; POST-TRANSLATIONAL MODIFICATIONS; PROTEOLYTIC DIGESTION; RECOMBINANT MONOCLONAL ANTIBODY; SAMPLE PREPARATION;

LIQUID CHROMATOGRAPHY;

DISULFIDE; GLYCAN; IMMUNOGLOBULIN HEAVY CHAIN; LYSINE; MONOCLONAL ANTIBODY; POLYPEPTIDE; RECOMBINANT ANTIBODY;

ARTICLE; ELECTROSPRAY MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY; OXIDATION; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN PROCESSING; PROTEIN SECRETION; STREPTOCOCCUS PYOGENES;

EID: 79958256412     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2011.04.030     Document Type: Article

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