Detecting and Quantifying Multiple Proteins in Clinical Samples in High-Throughput Using Antibody Microarrays

Methods in Molecular Biology

Volumn 723, Issue , 2011, Pages 3-13

  Knickerbocker, Tanya ^a   MacBeath, Gavin ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

Antibody microarray; Diagnosis; ELISA; High throughput; Prognosis; Sandwich immunoassay

Indexed keywords

BIOLOGICAL MARKER; IMMOBILIZED ANTIBODY; PROTEIN;

ANIMAL; ARTICLE; BLOOD; HUMAN; IMAGE PROCESSING; IMMUNOASSAY; IMMUNOLOGY; INSTRUMENTATION; METHODOLOGY; PRINTING; PROTEIN MICROARRAY; TIME;

ANIMALS; ANTIBODIES, IMMOBILIZED; BIOLOGICAL MARKERS; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; IMMUNOASSAY; PRINTING; PROTEIN ARRAY ANALYSIS; PROTEINS; TIME FACTORS;

EID: 79958250899     PISSN: 10643745     EISSN: 19406029     Source Type: Book Series    
DOI: 10.1007/978-1-61779-043-0_1     Document Type: Chapter

References (16)

1. Alizadeh AA, Eisen MB, Davis RE et al (2000) Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 403:503–511
2. Liang Y, Diehn M, Watson N et al (2005) Gene expression profiling reveals molecularly and clinically distinct subtypes of glioblastoma multiforme. Proc Natl Acad Sci U S A 102:5814–5819
3. Ramaswamy S, Tamayo P, Rifkin R et al (2001) Multiclass cancer diagnosis using tumor gene expression signatures. Proc Natl Acad Sci U S A 98:15149–15154
4. Zhou SF, Di YM, Chan E et al (2008) Clinical pharmacogenetics and potential application in personalized medicine. Curr Drug Metab 9:738–784
5. Duffy MJ, Crown J (2008) A personalized approach to cancer treatment: how biomarkers can help. Clin Chem 54:1770–1779
6. Hanash S (2003) Disease proteomics. Nature 422:226–232
7. Schweitzer B, Roberts S, Grimwade B et al (2002) Multiplexed protein profiling on microarrays by rolling-circle amplification. Nat Biotechnol 20:359–365
8. Shao W, Zhou Z, Laroche I et al (2003) Optimization of rolling-circle amplified protein microarrays for multiplexed protein profiling. J Biomed Biotechnol 5:299–307
9. Knickerbocker T, Chen JR, Thadhani R, MacBeath G (2007) An integrated approach to prognosis using protein microarrays and nonparametric methods. Mol Syst Biol 3(123):1–8
10. MacBeath G (2002) Protein microarrays and proteomics. Nat Genet 32:526–532
11. Li C, Simeone DM, Brenner DE et al (2009) Pancreatic cancer serum detection using a lec-tin/glyco-antibody array method. J Proteome Res 8:483–492
12. Belov L, Mulligan SP, Barber N et al (2006) Analysis of human leukaemias and lymphomas using extensive immunophenotypes from an antibody microarray. Br J Haematol 135: 184–197
13. Thadhani R, Tonelli M (2006) Cohort studies: marching forward. Clin J Am Soc Nephrol 1:1117–1123
14. USRSD (2005) National Institutes of Health. National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda
15. Buja A, Hastie T, Tibshirani R (1989) Linear smoothers and additive models (with discus-sion). Ann Statist 17:453–555
16. Natarajan M, Lin KM, Hsueh RC et al (2006) A global analysis of cross-talk in a mammalian cellular signalling network. Nat Cell Biol 8: 571–580