Implications for a general role of LPS-binding proteins (CD14, LBP) in combating bacterial infections

Innate Immunity

Volumn 5, Issue 1-2, 1999, Pages 75-80

  Schutt C ^a   Bernheiden, M ^a   Grunwald, U ^a   Stelter, F ^a   Menzel, R ^a   Muller H P ^a   Fan, X ^a   Jack, R S ^a  

^a UNIVERSITY OF GREIFSWALD   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 79958224421     PISSN: 17534259     EISSN: 17534267     Source Type: Journal    
DOI: 10.1177/09680519990050010601     Document Type: Article

References (18)

1. Rietschel ET, Kirikae T., Schade RUet al.Bacterial endotoxin: molecular relationships of structure to activity and function. FASEB J 1994; 8: 217-225.
2. Wright SD, Ramos RA, Tobias PS, Ulevitch RJ, Mathison JC CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science 1990; 249: 1431-1433.
3. Schumann RR, Leong SR, Flaggs GWet al.Structure and function of lipopolysaccharide binding protein. Science 1990; 249: 1429-1431.
4. Pugin J., Heumann D., Tomasz A.et al.CD14 is a pattern recognition receptor. Immunity 1994; 1: 509-516.
5. Soell M., Lett E., Holveck F., Schöller M., Wachsmann D., Klein JP Activation of human monocytes by streptococcal rhamnose glucose polymers is mediated by CD14 antigen, and mannan binding protein inhibits. J Immunol 1995; 154: 851-860.
6. Newman S.L. Chaturvedi S., Klein BS The WI-1 antigen of Blastomyces dermatidis yeast mediates binding to human macrophage CD11b/CD18 (CD3) and CD14. J Immunol 1995; 154: 753-761.
7. Espevik T., Otterlei M., Skyak-Break G., Ryan L., Wright SD, Sundan A. The involvement of CD14 in stimulation of cytokine production by uronic acid polymers. Eur J Immunol 1993; 23: 255-261.
8. Jack RS, Grunwald U., Stelter F., Workalemahu G., Schütt C. Both membrane-bound and soluble forms of CD14 bind to Gram-negative bacteria. Eur J Immunol 1995; 25: 1436-1441.
9. Grunwald U., Fan X., Jack RSet al.Monocytes can phagocytose Gram-negative bacteria by a CD14-dependent mechanism. J Immunol 1996; 157: 4119-4125.
10. Stelter F., Bernheiden M., Menzel R.et al.Mutation of amino acids 39-44 of human CD14 abrogates binding of lipopolysaccharide and Escherichia coli. Eur J Biochem 1997; 243: 100-109.
11. Jack RS, Fan X., Bernheiden M.et al.Lipopolysaccharide binding protein is required to combat a murine Gram-negative bacterial infection. Nature 1997; 389: 742-745.
12. Schütt C., Schilling T., Grunwald U., Schünfeld W., Krüger C. Endotoxin neutralizing capacity of soluble CD14. Res Immunol 1992; 143: 71-78.
13. Schiff DE, Kline L., Soldau K.et al.Phagocytosis of Gram-negative bacteria by a unique CD14-dependent mechanism. J Leukoc Biol 1997; 62: 786-794.
14. Onozuka K., Kirikae T., Kirikae F.et al.Participation of CD14 in the phagocytosis of smooth-Type Salmonella typhimurium by the macrophage-like cell line, J774.1. Microbiol Immunol 1997; 41: 765-772.
15. Yu B., Hailman E., Wright SD Lipopolysaccharide binding protein and soluble CD14 catalyze exchange of phospholipids. J Clin Invest 1997; 99: 315-324.
16. Devitt A., Moffatt OD, Raykundalia C., Capra JD, Simmons DL, Gregory CD Human CD14 mediates recognition and phagocytosis of apoptotic cells. Nature 1998; 392: 505-509.
17. Savill J. Phagocytic docking without shocking. Nature 1998; 392: 442-443.
18. Fadok VA, Bratton DL, Konowal A., Freed PW, Westcott JY, Henson PM Macrophages that have ingested apoptotic cells in vitro inhibit pro-inflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF. J Clin Invest 1998; 101: 890-898.