-
1
-
-
1542611579
-
Global perspectives of contemporary epidemiological trends of cutaneous malignant melanoma
-
DOI 10.1111/j.1365-2133.2004.05708.x
-
Lens MB, Dawes M. Global perspectives of contemporary epidemiological trends of cutaneous malignant melanoma. Br J Dermatol 2004;150:179-185. (Pubitemid 38352453)
-
(2004)
British Journal of Dermatology
, vol.150
, Issue.2
, pp. 179-185
-
-
Lens, M.B.1
Dawes, M.2
-
2
-
-
77954787488
-
On behalf of the American Joint Committee on Cancer (AJCC)Melanoma Staging Committee 2010 TNM Staging System for Cutaneous Melanoma and Beyond
-
Gershenwald JE, Soong SJ, Balch CM. On behalf of the American Joint Committee on Cancer (AJCC)Melanoma Staging Committee. 2010 TNM Staging System for Cutaneous Melanoma and Beyond. Ann Surg Oncol 2010;6:1475-1477.
-
(2010)
Ann Surg Oncol
, vol.6
, pp. 1475-1477
-
-
Gershenwald, J.E.1
Soong, S.J.2
Balch, C.M.3
-
3
-
-
70049104593
-
Genetics and genomics of melanoma
-
Ghosh P, Chin L. Genetics and genomics of melanoma. Expert Rev Dermatol 2009;4:131-143.
-
(2009)
Expert Rev Dermatol
, vol.4
, pp. 131-143
-
-
Ghosh, P.1
Chin, L.2
-
4
-
-
71149083533
-
Ascierto PA.Main roads to melanoma
-
Palmieri G, Capone M, Ascierto ML, Gentilcore G, Stroncek DF, Casula M, SiniMC, Palla M,Mozzillo N, Ascierto PA.Main roads to melanoma. J Transl Med 2009;7:86.
-
(2009)
J Transl Med
, vol.7
, pp. 86
-
-
Palmieri, G.1
Capone, M.2
Ascierto, M.L.3
Gentilcore, G.4
Stroncek, D.F.5
Casula, M.6
Sini, M.C.7
Palla, M.8
Mozzillo, N.9
-
5
-
-
0343621494
-
Aberrant CpG-island methylation has non-random and tumour-type-specific patterns
-
DOI 10.1038/72785
-
Costello JF, Frühwald MC, Smiraglia DJ, Rush LJ, Robertson GP, Gao X, Wright FA, Feramisco JD, Peltomäki P, Lang JC, Schuller DE, Yu L, Bloomfield CD, Caligiuri MA, Yates A, Nishikawa R, Su Huang H, Petrelli NJ, Zhang X, O'DorisioMS, HeldWA,Cavenee WK, Plass C. Aberrant CpG-island methylation has non-random and tumor specific patterns. Nature Genet 2000;24:132-138. (Pubitemid 30094712)
-
(2000)
Nature Genetics
, vol.24
, Issue.2
, pp. 132-138
-
-
Costello, J.F.1
Fruhwald, M.C.2
Smiraglia, D.J.3
Rush, L.J.4
Robertson, G.P.5
Gao, X.6
Wright, F.A.7
Feramisco, J.D.8
Peltomaki, P.9
Lang, J.C.10
Schuller, D.E.11
Yu, L.12
Bloomfield, C.D.13
Caligiuri, M.A.14
Yates, A.15
Nishikawa, R.16
Su Huang, H.-J.17
Petrelli, N.J.18
Zhang, X.19
O'Dorisio, M.S.20
Held, W.A.21
Cavenee, W.K.22
Plass, C.23
more..
-
6
-
-
0032960181
-
Cancer epigenetics comes of age
-
DOI 10.1038/5947
-
Jones PA, Laird PW. Cancer epigenetics comes of age. Nature Genet 1999;21:163-167. (Pubitemid 29070360)
-
(1999)
Nature Genetics
, vol.21
, Issue.2
, pp. 163-167
-
-
Jones, P.A.1
Laird, P.W.2
-
7
-
-
67650541135
-
Epigenetics in human melanoma
-
Howell P, Liu S, Ren S, Behlen C, FodstadO, Riker AI. Epigenetics in human melanoma. Cancer Control 2009;16:200-218.
-
(2009)
Cancer Control
, vol.16
, pp. 200-218
-
-
Howell, P.1
Liu, S.2
Ren, S.3
Behlen, C.4
Fodstad, O.5
Riker, A.I.6
-
8
-
-
11844302899
-
Promoter methylation profiling of 30 genes in human malignant melanoma
-
DOI 10.1111/j.1349-7006.2004.tb03184.x
-
Furuta J, Umebayashi Y, Miyamato K, Kikuchi K, Otsuka F, Sugimura T, Ushijima T. Promoter methylation profiling of 30 genes in human malignant melanoma. Cancer Sci 2004;95:962-968. (Pubitemid 40089588)
-
(2004)
Cancer Science
, vol.95
, Issue.12
, pp. 962-968
-
-
Furuta, J.1
Umebayashi, Y.2
Miyamoto, K.3
Kikuchi, K.4
Otsuka, F.5
Sugimura, T.6
Ushijima, T.7
-
9
-
-
27744548525
-
Multiple markers for melanoma progression regulated by DNA methylation: Insights from transcriptomic studies
-
DOI 10.1093/carcin/bgi152
-
Gallagher WM, Bergin OE, Rafferty M, Kelly ZD, Nolan IM, Fox EJ, Culhane AC, McArdle L, Fraga MF, Hughes L, Currid CA, O'Mahony F, Byrne A, Murphy AA, Moss C, McDonnell S, Stallings RL, Plumb JA, Esteller M, Brown R,Dervan PA, EastyDJ. Multiple markers for melanoma progression regulated by DNA methylation: insights from transcriptomic studies. Carcinogenesis 2005;26:1856-1867. (Pubitemid 41631258)
-
(2005)
Carcinogenesis
, vol.26
, Issue.11
, pp. 1856-1867
-
-
Gallagher, W.M.1
Rafferty, M.2
Kelly, Z.D.3
Nolan, I.-M.4
Fox, E.J.P.5
Culhane, A.C.6
McArdle, L.7
Fraga, M.F.8
Hughes, L.9
Currid, C.A.10
O'Mahony, F.11
Byrne, A.12
Murphy, A.A.13
Moss, C.14
McDonnell, S.15
Stallings, R.L.16
Plumb, J.A.17
Esteller, M.18
Brown, R.19
Dervan, P.A.20
Easty, D.J.21
more..
-
10
-
-
33845735043
-
Epigenetic silencing of novel tumor suppressors in malignant melanoma
-
DOI 10.1158/0008-5472.CAN-06-1274
-
Muthusamy V, Duraisamy S, Bradbury CM, Hobbs C, Curley DP, Nelson B, Bosenberg M. Epigenetic silencing of novel tumor suppressors in malignant melanoma. Cancer Res 2006;66:11187-11193. (Pubitemid 46009946)
-
(2006)
Cancer Research
, vol.66
, Issue.23
, pp. 11187-11193
-
-
Muthusamy, V.1
Duraisamy, S.2
Bradbury, C.M.3
Hobbs, C.4
Curley, D.P.5
Nelson, B.6
Bosenberg, M.7
-
11
-
-
33947305783
-
Epigenetic events in malignant melanoma
-
DOI 10.1111/j.1600-0749.2007.00367.x
-
Rothhammer T, Bosserhoff AK. Epigenetic events in malignant melanoma. Pigment Cell Res 2007;20:92-111. (Pubitemid 46439524)
-
(2007)
Pigment Cell Research
, vol.20
, Issue.2
, pp. 92-111
-
-
Rothhammer, T.1
Bosserhoff, A.-K.2
-
12
-
-
49649125674
-
Identification of novel epigenetically modified genes in human melanoma via promoter methylation gene profiling
-
Liu S, Ren S, Howell P, Fodstad O, Riker AI. Identification of novel epigenetically modified genes in human melanoma via promoter methylation gene profiling. Pigment Cell Melanoma Res 2008;21:545-558.
-
(2008)
Pigment Cell Melanoma Res
, vol.21
, pp. 545-558
-
-
Liu, S.1
Ren, S.2
Howell, P.3
Fodstad, O.4
Riker, A.I.5
-
13
-
-
84887212492
-
Integrative analysis of epigenetic modulation in melanoma cell response to decitabine: Clinical implications
-
Halaban R, Krauthammer M, Pelizzola M, Cheng E, Kovacs D, SznolM, Ariyan S,NarayanD, Bacchiocchi A,Molinaro A, Kluger Y, Deng M, Tran N, ZhangW, Picardo M, Enghild JJ. Integrative analysis of epigenetic modulation in melanoma cell response to decitabine: clinical implications. PLoS One 2009;4:e456.
-
(2009)
PLoS One
, vol.4
-
-
Halaban, R.1
Krauthammer, M.2
Pelizzola, M.3
Cheng, E.4
Kovacs, D.5
Lm, S.6
Ariyan, S.7
Narayan, D.8
Bacchiocchi, A.9
Molinaro, A.10
Kluger, Y.11
Deng, M.12
Tran, N.13
Zhang, W.14
Picardo, M.15
Enghild, J.J.16
-
14
-
-
0034682806
-
A novel human gene similar to the protein kinase (PK) coding domain of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10) codes for a serine-threonine PK and is expressed in melanoma cells
-
Smith CC, Yu YX, KulkaM, Aurelian L. A novel human gene similar to the protein kinase (PK) coding domain of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10) codes for a serine-threonine PK and is expressed in melanoma cells. J Biol Chem 2000;275:25690-25699.
-
(2000)
J Biol Chem
, vol.275
, pp. 25690-25699
-
-
Smith, C.C.1
Yu, Y.X.2
Kulka, M.3
Aurelian, L.4
-
15
-
-
0035116940
-
A novel gene expressed in human keratinocytes with long-term in vitro growth potential is required for cell growth
-
DOI 10.1046/j.1523-1747.2001.00191.x
-
Aurelian L, Smith CC, Winchurch R, Kulka M, Gyotoku T, Zaccaro L, Chrest FJ, Burnett JW. A novel gene expressed in human keratinocytes with long-term in vitro growth potential is required for cell growth. J Invest Dermatol 2001;116:286-295. (Pubitemid 32173734)
-
(2001)
Journal of Investigative Dermatology
, vol.116
, Issue.2
, pp. 286-295
-
-
Aurelian, L.1
Smith, C.C.2
Winchurch, R.3
Kulka, M.4
Gyotoku, T.5
Zaccaro, L.6
Chrest, F.J.7
Burnett, J.W.8
-
16
-
-
0035344104
-
Expression analysis and chromosome location of a novel gene (H11) associated with the growth of human melanoma cells
-
Yu X, Heller A, Liehr T, Smith CC, Aurelian L. Expression analysis and chromosome location of a novel gene (H11) associated with the growth of human melanoma cells. Int J Oncol 2001;18:905-911.
-
(2001)
Int J Oncol
, vol.18
, pp. 905-911
-
-
Yu, X.1
Heller, A.2
Liehr, T.3
Smith, C.C.4
Aurelian, L.5
-
17
-
-
0037195691
-
H11 kinase is a novel mediator of myocardial hypertrophy in vivo
-
DOI 10.1161/01.RES.0000044380.54893.4B
-
DepreC,HaseM, GaussinV,ZajacA,WangL,HittingerL,Ghaleh B, Yu X, Kudej RK, Wagner T, Sadoshima J, Vatner SF. H11 kinase is a novel mediator of cardiac hypertrophy in vivo. Circ Res 2002;91:1007-1014. (Pubitemid 35416637)
-
(2002)
Circulation Research
, vol.91
, Issue.11
, pp. 1007-1014
-
-
Depre, C.1
Hase, M.2
Gaussin, V.3
Zajac, A.4
Wang, L.5
Hittinger, L.6
Ghaleh, B.7
Yu, X.8
Kudej, R.K.9
Wagner, T.10
Sadoshima, J.11
Vatner, S.F.12
-
18
-
-
33644862630
-
H11 kinase preventsmyocardial infarction by preemptive preconditioning of the heart
-
Depre C, Wang L, Sui X, Qiu H, Hong C, Hedhli N, Ginion A, Shah A, Pelat M, Bertrand L, Wagner T, Gaussin V, Vatner SF. H11 kinase preventsmyocardial infarction by preemptive preconditioning of the heart. Circ Res 2006;98:280-288.
-
(2006)
Circ Res
, vol.98
, pp. 280-288
-
-
Depre, C.1
Wang, L.2
Sui, X.3
Qiu, H.4
Hong, C.5
Hedhli, N.6
Ginion, A.7
Shah, A.8
Pelat, M.9
Bertrand, L.10
Wagner, T.11
Gaussin, V.12
Vatner, S.F.13
-
19
-
-
34247272428
-
Therapeutic potential of H11 kinase for the ischemic heart
-
DOI 10.1111/j.1527-3466.2007.00002.x
-
Danan IJ, Rashed ER, Depre C. Therapeutic potential of H11 kinase for the ischemic heart. Cardiovasc Drug Rev 2007;25:14-29. (Pubitemid 46625288)
-
(2007)
Cardiovascular Drug Reviews
, vol.25
, Issue.1
, pp. 14-29
-
-
Danan, I.J.1
Rashed, E.R.2
Depre, C.3
-
20
-
-
0141844530
-
Forced expression of the H11 heat shock protein can be regulated by DNA methylation and trigger apoptosis in human cells
-
GoberMD, SmithCC,Ueda K, Toretsky JA,Aurelian L. Forced expression of the H11 heat shock protein can be regulated by DNA methylation and trigger apoptosis in human cells. J Biol Chem 2003;278:37600-37609.
-
(2003)
J Biol Chem
, vol.278
, pp. 37600-37609
-
-
Gober, M.D.1
Smith, C.C.2
Ueda, K.3
Toretsky, J.A.4
Aurelian, L.5
-
21
-
-
21344465226
-
Herpes simplex virus type 2 encodes a heat shock protein homologue with apoptosis regulatory functions
-
GoberMD,Wales SQ, Aurelian L.Herpes simplex virus type 2 encodes a heat shock protein homologue with apoptosis regulatory functions. Front Biosci 2005;10:2788-2803. (Pubitemid 40905275)
-
(2005)
Frontiers in Bioscience
, vol.10
, Issue.SUPPL. 2
, pp. 2788-2803
-
-
Gober, M.D.1
Wales, S.Q.2
Aurelian, L.3
-
22
-
-
3242776825
-
Mammalian Hsp22 is a heat-inducible small heat-shock protein with chaperone-like activity
-
DOI 10.1042/BJ20031958
-
Chowdary TK, Ramon B, Ramakrishna T, Raos CM. Mammalian Hsp22 is a heat inducible small heat-shock protein with chaperone-like activity. Biochem J 2004;381:379-387. (Pubitemid 38969681)
-
(2004)
Biochemical Journal
, vol.381
, Issue.2
, pp. 379-387
-
-
Chowdary, T.K.1
Raman, B.2
Ramakrishna, T.3
Rao, C.M.4
-
23
-
-
34249337421
-
Overload of the heat-shock protein H11/HspB8 triggers melanoma cell apoptosis through activation of transforming growth factor-β-activated kinase 1
-
DOI 10.1038/sj.onc.1210145, PII 1210145
-
Li B, Smith CC, Laing JM, Liu L, Aurelian L. Overload of the heat-shock protein H11/HspB8 triggers melanoma cell apoptosis through activation of transforming growth factor-b-activated kinase 1. Oncogene 2007;26:3521-3531. (Pubitemid 46816763)
-
(2007)
Oncogene
, vol.26
, Issue.24
, pp. 3521-3531
-
-
Li, B.1
Smith, C.C.2
Laing, J.M.3
Gober, M.D.4
Liu, L.5
Aurelian, L.6
-
24
-
-
0035380769
-
Heterogeneousmethylation of theO( 6)-methylguanine-DNAmethyltransferase promoter in immortalized IMR90 cell lines
-
Danam RP, Howell SR, Remack JS, Brent TP. Heterogeneousmethylation of theO(6)-methylguanine-DNAmethyltransferase promoter in immortalized IMR90 cell lines. Int J Oncol 2001;18:1187-1193.
-
(2001)
Int J Oncol
, vol.18
, pp. 1187-1193
-
-
Danam, R.P.1
Howell, S.R.2
Remack, J.S.3
Brent, T.P.4
-
25
-
-
42049113246
-
Immunohistochemical characteristics of melanoma
-
DOI 10.1111/j.1600-0560.2007.00891.x
-
Ohsie SJ, Sarantopoulos GP, Cochran AJ, Binder SW. Immunohistochemical characteristics of melanoma. J Cutan Pathol 2008;35:433-444. (Pubitemid 351519417)
-
(2008)
Journal of Cutaneous Pathology
, vol.35
, Issue.5
, pp. 433-444
-
-
Ohsie, S.J.1
Sarantopoulos, G.P.2
Cochran, A.J.3
Binder, S.W.4
-
26
-
-
56149088621
-
Quantitative detection of methylated ESR1 and 14-3-3-sigma gene promoters in serum as candidate biomarkers for diagnosis of breast cancer and evaluation of treatment efficacy
-
Martinez-Galan J, Torres B, Del Moral R, Munoz-Gamez JA, Martin-Oliva D, Villalobos M, Nunez MI, Luna Jde D, Oliver FJ, Ruiz de Almodovar JM. Quantitative detection of methylated ESR1 and 14-3-3-sigma gene promoters in serum as candidate biomarkers for diagnosis of breast cancer and evaluation of treatment efficacy. Cancer BiolTher 2008;7:958-965.
-
(2008)
Cancer Biol Ther
, vol.7
, pp. 958-965
-
-
Martinez-Galan, J.1
Torres, B.2
Del Moral, R.3
Munoz-Gamez, J.A.4
Martin-Oliva, D.5
Villalobos, M.6
Nunez, M.I.7
Luna Jde, D.8
Oliver, F.J.9
Ruiz De Almodovar, J.M.10
-
27
-
-
42649109339
-
Methylation-specific and SYBR-green-based quantitative polymerase chain reaction technique for O6-methylguanine DNA methyltransferase promoter methylation analysis
-
Hatterman K, Mehdorn HM, Mentlein R, Schultka S, Held- Feindt JA. Methylation-specific and SYBR-green-based quantitative polymerase chain reaction technique for O6-methylguanine DNA methyltransferase promoter methylation analysis. Anal Biochem 2008;377:62-71.
-
(2008)
Anal Biochem
, vol.377
, pp. 62-71
-
-
Hatterman, K.1
Mehdorn, H.M.2
Mentlein, R.3
Schultka, S.4
Held-Feindt, J.A.5
-
28
-
-
0028909645
-
Human cyclin E, a nuclear protein essential for the G1-to-S phase transition
-
Ohtsubo M, Theodoras AM, Schumacher J, Roberts JM, Pagano M. Human cyclin E, a nuclear protein essential for the G1-to-S phase transition. Mol Cell Biol 1995;25:2612-2624.
-
(1995)
Mol Cell Biol
, vol.25
, pp. 2612-2624
-
-
Ohtsubo, M.1
Theodoras, A.M.2
Schumacher, J.3
Roberts, J.M.4
Pagano, M.5
-
29
-
-
0029009876
-
Different roles for cyclins D1 and e in regulation of the G1-to-S transition
-
Resnitzky D, Reed S. Different roles for cyclins D1 and E in regulation of the G1-to-S transition.Mol Cell Biol 1995;27:3463-3469.
-
(1995)
Mol Cell Biol
, vol.27
, pp. 3463-3469
-
-
Resnitzky, D.1
Reed, S.2
-
30
-
-
33846600427
-
PTEN-deficient intestinal stem cells initiate intestinal polyposis
-
DOI 10.1038/ng1928, PII NG1928
-
He KC, Yin T, Grindley JC, Tian Q, Sato T, Tao WA, Dirsina R, Porter-Wastphal T,Hembree M, Johnson T,Wiedemann LM, Barrett TA, Hood L, Wu H, Li L. PTEN-deficient stem cells initiate intestinal polyposis. Nat Genet 2007;39:189-198. (Pubitemid 46184349)
-
(2007)
Nature Genetics
, vol.39
, Issue.2
, pp. 189-198
-
-
He, X.C.1
Yin, T.2
Grindley, J.C.3
Tian, Q.4
Sato, T.5
Tao, W.A.6
Dirisina, R.7
Porter-Westpfahl, T.8
Hembree, M.9
Johnson, T.10
Wiedemann, L.M.11
Barrett, T.A.12
Hood, L.13
Wu, H.14
Li, L.15
-
31
-
-
36049017658
-
LEF-1 activates the transcription of E2F1
-
DOI 10.1016/j.bbrc.2007.10.138, PII S0006291X07023248
-
Zhou F, Zhang L, Gong K, Lu G, Sheng B,Wang A, Zhao N, Zhang X, Gong Y. LEF-1 activates the transcription of E2F1. Biochem Biophys Res Comm 2008;365:149-153. (Pubitemid 350102466)
-
(2008)
Biochemical and Biophysical Research Communications
, vol.365
, Issue.1
, pp. 149-153
-
-
Zhou, F.1
Zhang, L.2
Gong, K.3
Lu, G.4
Sheng, B.5
Wang, A.6
Zhao, N.7
Zhang, X.8
Gong, Y.9
-
32
-
-
0036571011
-
Axin-mediated CKI phosphorylation of β-catenin at Ser 45: A molecular switch for the Wnt pathway
-
DOI 10.1101/gad.230302
-
Amit S, Hatzubai A, Birman Y, Andersen JS, Ben-Shushan E, Mann M, Ben-Neriah Y, Alkalay I. Axin-mediated CK1 phosphorylation of beta-catenin at Ser 45: amolecular switch for theWNT pathway. Genes Dev 2002;16:1066-1076. (Pubitemid 34507196)
-
(2002)
Genes and Development
, vol.16
, Issue.9
, pp. 1066-1076
-
-
Amit, S.1
Hatzubai, A.2
Birman, Y.3
Andersen, J.S.4
Ben-Shushan, E.5
Mann, M.6
Ben-Neriah, Y.7
Alkalay, I.8
-
33
-
-
2442616062
-
Modulation of β-Catenin Phosphorylation/Degradation by Cyclin-dependent Kinase 2
-
DOI 10.1074/jbc.M314208200
-
Park CS, Kim SI, Lee MS, Youn CY, Kim DJ, Jho EH, Song WK. Modulation of beta-catenin phosphorylation/degradation by cyclin-dependent kinase 2. J Biol Chem 2004;279:19592-19599. (Pubitemid 38623395)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.19
, pp. 19592-19599
-
-
Park, C.S.1
Kim, S.I.2
Lee, M.S.3
Youn, C.-Y.4
Kim, D.J.5
Jho, E.-H.6
Song, W.K.7
-
34
-
-
33744519452
-
Phosphorylation of β-catenin by cyclic AMP-dependent protein kinase
-
DOI 10.1074/jbc.M508778200
-
Tauren S, Sanbo N, Qin Y, Browining D, Dulin NO. Phosphorylation of beta-catenin by cyclic AMP-dependent protein kinase. J Biol Chem 2006;281:9971-9976. (Pubitemid 43864529)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.15
, pp. 9971-9976
-
-
Taurin, S.1
Sandbo, N.2
Qin, Y.3
Browning, D.4
Dulin, N.O.5
-
37
-
-
21344456180
-
The Ras/Raf/MEK/ERK and PI3K/AKT signaling pathways present molecular targets for the effective treatment of advanced melanoma
-
Meier F, SchittekB, BuschS,GarbeC, SmalleyK, SatyamoorthyK, Li G, Herlyn M. The RAS/RAF/MEK/ERK and PI3K/AKT signaling pathways present molecular targets for the effective treatment of advanced melanoma. Front Biosci 2005;10:2986-3001. (Pubitemid 40910537)
-
(2005)
Frontiers in Bioscience
, vol.10
, Issue.SUPPL. 3
, pp. 2986-3001
-
-
Meier, F.1
Schittek, B.2
Busch, S.3
Garbe, C.4
Smalley, K.5
Satyamoorthy, K.6
Li, G.7
Herlyn, M.8
-
38
-
-
0036632368
-
The phosphatidylinositol 3-kinase-AKT pathway in human cancer
-
Vivanco I, Sawyers CL. The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nat Rev Cancer 2002;2:489-501. (Pubitemid 37328931)
-
(2002)
Nature Reviews Cancer
, vol.2
, Issue.7
, pp. 489-501
-
-
Vivanco, I.1
Sawyers, C.L.2
-
39
-
-
0037115394
-
Constitutive activation of Akt/protein kinase B in melanoma leads to up-regulation of nuclear factor-κB and tumor progression
-
Dhawan P, Singh AB, Ellis DL, Richmond A. Constitutive activation of Akt/protein kinase B in melanoma leads to up-regulation of nuclear factor-kappaB and tumor progression. Cancer Res 2002;62:7335-7342. (Pubitemid 36025257)
-
(2002)
Cancer Research
, vol.62
, Issue.24
, pp. 7335-7342
-
-
Dhawan, P.1
Singh, A.B.2
Ellis, D.L.3
Richmond, A.4
-
40
-
-
4944249733
-
Deregulated Akt3 activity promotes development of malignant melanoma
-
DOI 10.1158/0008-5472.CAN-04-1399
-
Stahl JM, Sharma A, Cheung M, Zimmerman M, Cheng JQ, Bosenberg MW, Kester M, Sandirasegarane L, Robertson GP. Deregulated Akt3 activity promotes development of malignant melanoma. Cancer Res 2004;64:7002-7010. (Pubitemid 39331010)
-
(2004)
Cancer Research
, vol.64
, Issue.19
, pp. 7002-7010
-
-
Stahl, J.M.1
Sharma, A.2
Cheung, M.3
Zimmerman, M.4
Cheng, J.Q.5
Bosenberg, M.W.6
Kester, M.7
Sandirasegarane, L.8
Robertson, G.P.9
-
41
-
-
67349103358
-
Inhibition of PI3K-AKT-mTOR signaling sensitizes melanoma cells to cisplatin and temozolomide
-
Sinnberg T, Lasithiotakis K, Niessner H, Schittek B, Flaherty KT, Kulms D, Maczey E, Campos M, Gogel J, Garbe C, Meier F. Inhibition of PI3K-AKT-mTOR signaling sensitizes melanoma cells to cisplatin and temozolomide. J Invest Dermatol 2009;129:1500-1515.
-
(2009)
J Invest Dermatol
, vol.129
, pp. 1500-1515
-
-
Sinnberg, T.1
Lasithiotakis, K.2
Niessner, H.3
Schittek, B.4
Flaherty, K.T.5
Kulms, D.6
MacZey, E.7
Campos, M.8
Gogel, J.9
Garbe, C.10
Meier, F.11
-
42
-
-
77954661329
-
Aberrant DNA methylation in malignant melanoma
-
Schinke C, Mo Y, Yu Y, Amiri K, Sosman J, Greally J, Verma A. Aberrant DNA methylation in malignant melanoma. Melanoma Res 2010;20:253-265.
-
(2010)
Melanoma Res
, vol.20
, pp. 253-265
-
-
Schinke, C.1
Mo, Y.2
Yu, Y.3
Amiri, K.4
Sosman, J.5
Greally, J.6
Verma, A.7
-
43
-
-
77953306334
-
Epigenetics of human cutaneous melanoma: Setting the stage for new therapeutic strategies
-
Sigalotti L, Covre A, Fratta E, Paris G, Colizzi F, Rizzo A, Danielli R, Nicolay HJ, Coral S, Maio M. Epigenetics of human cutaneous melanoma: setting the stage for new therapeutic strategies. J Transl Med 2010;8:56.
-
(2010)
J Transl Med
, vol.8
, pp. 56
-
-
Sigalotti, L.1
Covre, A.2
Fratta, E.3
Paris, G.4
Colizzi, F.5
Rizzo, A.6
Danielli, R.7
Nicolay, H.J.8
Coral, S.9
Maio, M.10
-
44
-
-
44949106363
-
ARF in human melanoma
-
DOI 10.1093/jnci/djn157
-
Freedburg DE, Rigas SH, Russak J, Gai W, Kaplow M, Osman I, Turner F, Randerson-Moor JA, Houghton A, Busam K, Timothy BD, Bastian BC, Newton-Bishop JA, Polsky D. Frequent p16- independent inactivation of p14ARF in human melanoma. J Natl Cancer Inst 2008;100:784-795. (Pubitemid 351809672)
-
(2008)
Journal of the National Cancer Institute
, vol.100
, Issue.11
, pp. 784-795
-
-
Freedberg, D.E.1
Rigas, S.H.2
Russak, J.3
Gai, W.4
Kaplow, M.5
Osman, I.6
Turner, F.7
Randerson-Moor, J.A.8
Houghton, A.9
Busam, K.10
Timothy Bishop, D.11
Bastian, B.C.12
Newton-Bishop, J.A.13
Polsky, D.14
-
45
-
-
2542522279
-
Profiling epigenetic inactivation of tumor suppressor genes in tumors and plasma from cutaneous melanoma patients
-
DOI 10.1038/sj.onc.1207505
-
HoonDS, SpugnardiM,Kuo C, Huang SK, MortonDL,Taback B. Profiling epigenetic inactivation of tumor suppressor genes in tumors and plasma from cutaneous melanoma patients. Oncogene 2004;23:4014-4022. (Pubitemid 38747930)
-
(2004)
Oncogene
, vol.23
, Issue.22
, pp. 4014-4022
-
-
Hoon, D.S.B.1
Spugnardi, M.2
Kuo, C.3
Huang, S.K.4
Morton, D.L.5
Taback, B.6
-
46
-
-
33645050917
-
Expression of RASSF1A, an epigenetically silenced tumor suppressor, overcomes resistance to apoptosis induction by interferons
-
Reu FJ, Leaman DW, Maitra RR, Bae SI, Cherkassky L, Fox MW, Rempinski DR, Beaulieu N,MacLeod AR, Borden EC. Expression of RASSF1A, an epigenetically silenced tumor suppressor, overcomes resistance to apoptosis induction by interferons. Cancer Res 2006;66:2785-2793.
-
(2006)
Cancer Res
, vol.66
, pp. 2785-2793
-
-
Reu, F.J.1
Leaman, D.W.2
Maitra, R.R.3
Bae, S.I.4
Cherkassky, L.5
Fox, M.W.6
Rempinski, D.R.7
Beaulieu, N.8
MacLeod, A.R.9
Borden, E.C.10
-
47
-
-
65249153121
-
Activation of the bone morphogenetic protein receptor by H11kinase/Hsp22 promotes cardiac cell growth and survival
-
Sui X, Li D, Qiu H, Gaussin V, Depre C. Activation of the bone morphogenetic protein receptor by H11kinase/Hsp22 promotes cardiac cell growth and survival. Circ Res 2009;104:887-895.
-
(2009)
Circ Res
, vol.104
, pp. 887-895
-
-
Sui, X.1
Li, D.2
Qiu, H.3
Gaussin, V.4
Depre, C.5
-
48
-
-
65449170415
-
Protective effect of geranylgeranylacetone via enhancement of HSPB8 induction in desminrelated cardiomyopathy
-
Sanbe A, Daicho T, Mizutani R, Endo T, Miyauchi N, Yamauchi J, Tanonaka K, Glabe C, Tanoue A. Protective effect of geranylgeranylacetone via enhancement of HSPB8 induction in desminrelated cardiomyopathy. PLoS One 2009;4:e5351.
-
(2009)
PLoS One
, vol.4
-
-
Sanbe, A.1
Daicho, T.2
Mizutani, R.3
Endo, T.4
Miyauchi, N.5
Yamauchi, J.6
Tanonaka, K.7
Glabe, C.8
Tanoue, A.9
-
49
-
-
0029097759
-
Radiation-induced cell cycle arrest compromised by p21 deficiency
-
Brugarolas J, Chandrasekaran C, Gordon JI, Beach D, Jacks T, Hannon GJ. Radiation-induced cell cycle arrest compromised by p21 deficiency. Nature 1995;377:552-557.
-
(1995)
Nature
, vol.377
, pp. 552-557
-
-
Brugarolas, J.1
Chandrasekaran, C.2
Gordon, J.I.3
Beach, D.4
Jacks, T.5
Hannon, G.J.6
-
50
-
-
0028978183
-
Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control
-
Deng C, Zhang P, Harper JW, Elledge SJ, Leder P. Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control. Cell 1995;82:675-684.
-
(1995)
Cell
, vol.82
, pp. 675-684
-
-
Deng, C.1
Zhang, P.2
Harper, J.W.3
Elledge, S.J.4
Leder, P.5
-
51
-
-
33645726418
-
The dual specificity phosphatase Cdc25C is a direct target for transcriptional repression by the tumor suppressor p53
-
St. Clair S, Manfredi JJ. The dual specificity phosphatase Cdc25C is a direct target for transcriptional repression by the tumor suppressor p53. Cell Cycle 2006;5:709-713.
-
(2006)
Cell Cycle
, vol.5
, pp. 709-713
-
-
St. Clair, S.1
Manfredi, J.J.2
-
52
-
-
24944548316
-
The continuing saga of p53 - More sleepless nights ahead
-
DOI 10.1016/j.molcel.2005.08.024, PII S1097276505015662
-
Prives C,Manfredi JJ. The continuing saga of p53-more sleepless nights ahead. Cell 2005;19:719-721. (Pubitemid 41316665)
-
(2005)
Molecular Cell
, vol.19
, Issue.6
, pp. 719-721
-
-
Prives, C.1
Manfredi, J.J.2
-
53
-
-
0035797528
-
Relative frequency and morphology of cancers in carriers of germline TP53 mutations
-
DOI 10.1038/sj.onc.1204621
-
Birch JM, Alston RD, McNally RJ, Evans DG, Kelsey AM, Harris M, Eden OB, Varley JM. Relative frequency and morphology of cancers in carriers of germline TP53 mutations. Oncogene 2001;20:4621-4628. (Pubitemid 32762434)
-
(2001)
Oncogene
, vol.20
, Issue.34
, pp. 4621-4628
-
-
Birch, J.M.1
Alston, R.D.2
McNally, R.J.Q.3
Evans, D.G.R.4
Kelsey, A.M.5
Harris, M.6
Eden, O.B.7
Varley, J.M.8
-
54
-
-
0037222380
-
TP53 mutations in familial breast cancer: Functional aspects
-
DOI 10.1002/humu.10173
-
Gasco M, Yulug IG, Crook T. TP53 mutations in familial breast cancer: functional aspects. Hum Mutat 2003;3:301-306. (Pubitemid 36292972)
-
(2003)
Human Mutation
, vol.21
, Issue.3
, pp. 301-306
-
-
Gasco, M.1
Yulug, I.G.2
Crook, T.3
-
55
-
-
0023573963
-
The EORTC Early Clinical Trials Cooperative Group experience with 5-aza-2'-deoxycytidine (NSC 127716) in patients with colo-rectal, head and neck, renal carcinomas and malignant melanomas
-
DOI 10.1016/0277-5379(87)90060-5
-
Abele R, Clavel M, Dodian P, Bruntsch U, Gunderson S, Smythe J, Renard J, van Glabbeke M, Pinedo HM. The EORTC Early Clinical Trials Cooperative Group experience with 5′-aza-2′- deoxycytidine (NSC 127716) in patients with colo-rectal, head and next, renal carcinomas andmalignantmelanomas. Eur J Cancer Clin Oncol 1987;23:1921-1924. (Pubitemid 18013335)
-
(1987)
European Journal of Cancer and Clinical Oncology
, vol.23
, Issue.12
, pp. 1921-1924
-
-
Abele, R.1
Clavel, M.2
Dodion, P.3
Bruntsch, U.4
Gundersen, S.5
Smyth, J.6
Renard, J.7
Van Glabbeke, M.8
Pinedo, H.M.9
-
56
-
-
37249031406
-
Epigenetic lesions in malignant melanoma
-
DOI 10.2174/138920107783018372
-
Schwabe M, Lubbert M. Epigenetic lesions in malignant melanoma. Curr Pharm Biotechnol 2007;8:382-387. (Pubitemid 350268197)
-
(2007)
Current Pharmaceutical Biotechnology
, vol.8
, Issue.6
, pp. 382-387
-
-
Schwabe, M.1
Lubbert, M.2
-
57
-
-
33747339752
-
Overcoming resistance to interferon-induced apoptosis of renal carcinoma and melanoma cells by DNA demethylation
-
DOI 10.1200/JCO.2005.03.4074
-
Reu FJ, Bae SI, Cherkassky L, Leaman DW, Lindner D, Beaulieu N, MacLeod AR, Borden EC. Overcoming resistance to interferon-induced apoptosis of renal carcinoma and melanoma cells by DNA methylation. J Clin Oncol 2006;24:3771-3779. (Pubitemid 46622316)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.23
, pp. 3771-3779
-
-
Reu, F.J.1
Soo, I.B.2
Cherkassky, L.3
Leaman, D.W.4
Lindner, D.5
Beaulieu, N.6
MacLeod, A.R.7
Borden, E.C.8
-
58
-
-
33748046812
-
Phase I trial of sequential low-dose 5-aza-2′-deoxycytidine plus high-dose intravenous bolus interleukin-2 in patients with melanoma or renal cell carcinoma
-
DOI 10.1158/1078-0432.CCR-06-0883
-
Gollob JA, Schlambi CJ, Peterson BL, Richmond T,Thoreson M, Moran K, DressmanHK, Jelinek J, Issa JP. Phase I trial of sequential low-dose 5-aza-2′-deoxycytidine plus high-dose intravenous bolus interleukin-2 in patients with melanoma or renal cell carcinoma. Clin Cancer Res 2006;12:4619-4627. (Pubitemid 44297813)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.15
, pp. 4619-4627
-
-
Gollob, J.A.1
Sciambi, C.J.2
Peterson, B.L.3
Richmond, T.4
Thoreson, M.5
Moran, K.6
Dressman, H.K.7
Jelinek, J.8
Issa, J.-P.J.9
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