Controlled and sustained gene delivery from injectable, porous PLGA scaffolds

Journal of Biomedical Materials Research - Part A

Volumn 98 A, Issue 1, 2011, Pages 72-79

  Jeon, Oju ^a   Krebs, Melissa ^a   Alsberg, Eben ^a,b  

^a Case Western Reserve University   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

biomaterials; controlled release; gene delivery; injectable; porosity; tissue engineering

Indexed keywords

CELL MIGRATION; CELLULAR MIGRATION; CHEMOKINES; CONTROLLED RELEASE; EXTRACELLULAR MATRICES; GENE DELIVERY; GENE TRANSFECTION; GROWTH FACTOR; HEK293 CELLS; HOST CELLS; IN-SITU; IN-SITU FORMING; INJECTABLE; INVASIVE SURGERY; LOCALIZED DELIVERY; MICRO-SCALES; MINIMALLY INVASIVE; PLASMID DNA (PDNA); PLGA MICROSPHERES; PLGA SCAFFOLDS; POLY(LACTIC-CO-GLYCOLIC ACID); POROUS SCAFFOLD; RAPID RELEASE; RELEASE PROFILES; SUSTAINED RELEASE; SYSTEM COMPOSITION; THERAPEUTIC MOLECULES; TIME COURSE; TIME POINTS; TIME-PERIODS;

CYTOLOGY; GENE THERAPY; GENE TRANSFER; PEPTIDES; TISSUE;

SCAFFOLDS (BIOLOGY);

DNA; MICROSPHERE; MOLECULAR SCAFFOLD; POLYGLACTIN;

ARTICLE; CELL MIGRATION; CELL PROLIFERATION; EXTRACELLULAR MATRIX; GENE DELIVERY SYSTEM; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; POROSITY; SUSTAINED DRUG RELEASE;

BETA-GALACTOSIDASE; DNA; GENE TRANSFER TECHNIQUES; HEK293 CELLS; HUMANS; INJECTIONS; LACTIC ACID; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; PARTICLE SIZE; PLASMIDS; POLYGLYCOLIC ACID; POROSITY;

EID: 79958188199     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.33098     Document Type: Article

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