A proton nuclear magnetic resonance metabonomics approach for biomarker discovery in nonalcoholic fatty liver disease

Journal of Proteome Research

Volumn 10, Issue 6, 2011, Pages 2797-2806

  Li, Hao ^a,b   Wang, Lan ^c   Yan, Xianzhong ^d   Liu, Qijun ^a,e   Yu, Chaohui ^c   Wei, Handong ^a   Li, Youming ^c   Zhang, Xuemin ^d   He, Fuchu ^a,f   Jiang, Ying ^a  

^a BEIJING INSTITUTE OF RADIATION MEDICINE   (China)

^b BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY   (China)

^c ZHEJIANG UNIVERSITY   (China)

^d NATIONAL CENTER OF BIOMEDICAL ANALYSIS   (China)

^e NATIONAL UNIVERSITY OF DEFENSE TECHNOLOGY   (China)

^f FUDAN UNIVERSITY   (China)

Author keywords

artificial neural networks; metabonomics; multinomial logistic regression; nonalcoholic fatty liver disease; noninvasive diagnosis biomarkers; proton nuclear magnetic resonance; serum

Indexed keywords

BIOLOGICAL MARKER; CHOLINE; GLUCOSE; GLUTAMIC ACID; GLUTAMINE; LACTIC ACID; METHIONINE; TAURINE;

ADULT; AMINO ACID BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTIFICIAL NEURAL NETWORK; CLINICAL ARTICLE; CLUSTER ANALYSIS; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; EARLY DIAGNOSIS; FEMALE; GLUCOSE BLOOD LEVEL; HEPATITIS; HUMAN; LACTATE BLOOD LEVEL; MALE; METABOLITE; METABOLOMICS; MOUSE; NON INVASIVE PROCEDURE; NONALCOHOLIC FATTY LIVER; NONHUMAN; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE;

ADULT; ANIMALS; BIOLOGICAL MARKERS; BLOOD GLUCOSE; DIET; FATTY LIVER; FEMALE; GLUTAMIC ACID; HUMANS; LACTIC ACID; LOGISTIC MODELS; MAGNETIC RESONANCE SPECTROSCOPY; MALE; METABOLOMICS; MICE; MICE, INBRED C57BL; MIDDLE AGED; PRINCIPAL COMPONENT ANALYSIS; TAURINE;

MUS;

EID: 79958186715     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr200047c     Document Type: Article

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