Trimerization of murine TNF ligand family member LIGHT increases the cytotoxic activity against the FM3A mammary carcinoma cell line

Applied Microbiology and Biotechnology

Volumn 90, Issue 5, 2011, Pages 1691-1699

  Ito, Tatsuo ^a   Iwamoto, Keiji ^a   Tsuji, Isamu ^a   Tsubouchi, Hideto ^a   Omae, Hiroaki ^a   Sato, Takayuki ^a   Ohba, Hiroyoshi ^a   Kurokawa, Tomofumi ^a   Taniyama, Yoshio ^a   Shintani, Yasushi ^a  

^a TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

Author keywords

FM3A; Foldon; Herpes virus entry mediator; LIGHT; Lymphotoxin receptor; Trimer

Indexed keywords

BACTERIOPHAGE T4; CELL SURFACES; CYTOTOXIC ACTIVITIES; E. COLI; FM3A; FOLDON; HERPES VIRUS ENTRY MEDIATOR; IMMUNE RESPONSE; INHIBITORY ACTIVITY; MAMMALIAN CELLS; MAMMARY CARCINOMA CELL; NANOMOLAR CONCENTRATION; RECOMBINANT PROTEIN; SOLUBLE PROTEINS; TRIMER; TRIMERIZATION; TUMOR NECROSIS FACTORS;

BACTERIOPHAGES; BIOACTIVITY; CELL CULTURE; CELL MEMBRANES; CHEMICAL REACTIONS; CYTOTOXICITY; ESCHERICHIA COLI; LIGANDS; MAMMALS; PROTEINS;

DIMERS;

ANTINEOPLASTIC AGENT; HERPESVIRUS ENTRY MEDIATOR LIGAND; MONOMER; MOUSE LIGHT PROTEIN; RECOMBINANT CYTOKINE; UNCLASSIFIED DRUG;

BIOACTIVITY; CELL ORGANELLE; COLIFORM BACTERIUM; IMMUNE RESPONSE; LIGAND; MEMBRANE; PROTEIN; RECOMBINATION; RODENT; SOLUBILIZATION; TOXICITY; TOXIN; TUMOR;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; BREAST CARCINOMA; CANCER GROWTH; CARCINOMA CELL; CELL ASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; IC 50; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN MODIFICATION; TRIMERIZATION;

ANIMALS; BIOLOGICAL ASSAY; CELL LINE, TUMOR; CYTOTOXICITY, IMMUNOLOGIC; HUMANS; MICE; PROTEIN MULTIMERIZATION; RECOMBINANT FUSION PROTEINS; SOLUBILITY; TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 14;

ESCHERICHIA COLI; HERPESVIRIDAE; MAMMALIA; MURINAE;

EID: 79958154343     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-011-3168-8     Document Type: Article

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