메뉴 건너뛰기




Volumn 70, Issue 10, 2010, Pages 3965-3974

Deregulated estrogen receptor α and p53 heterozygosity collaborate in the development of mammary hyperplasia

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CYCLIN DEPENDENT KINASE INHIBITOR 1B; ESTROGEN RECEPTOR ALPHA; GLYCOPROTEIN P; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; PROTEIN P27; PROTEIN P53; PROTEIN TYROSINE KINASE;

EID: 77952848351     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-09-3450     Document Type: Article
Times cited : (24)

References (50)
  • 1
    • 34547816651 scopus 로고    scopus 로고
    • Breast cancer incidence, 1980-2006: Combined roles of menopausal hormone therapy, screening mammography, and estrogen receptor status
    • Glass AG, Lacey JV, Jr., Carreon JD, Hoover RN. Breast cancer incidence, 1980-2006: combined roles of menopausal hormone therapy, screening mammography, and estrogen receptor status. J Natl Cancer Inst 2007;99:1152-1161
    • (2007) J Natl Cancer Inst , vol.99 , pp. 1152-1161
    • Glass, A.G.1    Lacey Jr., J.V.2    Carreon, J.D.3    Hoover, R.N.4
  • 2
    • 0032945578 scopus 로고    scopus 로고
    • The transition from hyperplasia to invasive carcinoma of the breast
    • DOI 10.1002/(SICI)1096-9896(199902)187:3<272::AID-PATH265>3.0.CO;2- 2
    • Lakhani S.R. The transition from hyperplasia to invasive carcinoma of the breast Journal of Pathology 1999 187 3 272-278 DOI 10.1002/(SICI)1096- 9896(199902)187:3<272::AID-PATH265>3.0.CO;2-2 2. Lakhani SR. The transition from hyperplasia to invasive carcinoma of the breast. J Pathol 1999;187:272-278 (Pubitemid 29064150)
    • (1999) Journal of Pathology , vol.187 , Issue.3 , pp. 272-278
    • Lakhani, S.R.1
  • 4
    • 0026093508 scopus 로고
    • Loss of chromosome 17p13 sequences and mutation of p53 in human breast carcinomas
    • Varley J.M. Brammar W.J. Lane D.P. Swallow J.E. Dolan C. Walker R.A. Loss of chromosome 17p13 sequences and mutation of p53 in human breast carcinomas Oncogene 1991 6 3 413-421 4. Varley JM, Brammar WJ, Lane DP, Swallow JE, Dolan C, Walker RA. Loss of chromosome 17p13 sequences and mutation of p53 in human breast carcinomas. Oncogene 1991;6:413-421 (Pubitemid 21924097)
    • (1991) Oncogene , vol.6 , Issue.3 , pp. 413-421
    • Varley, J.M.1    Brammar, W.J.2    Lane, D.P.3    Swallow, J.E.4    Dolan, C.5    Walker, R.A.6
  • 5
    • 0027992938 scopus 로고
    • The p53 tumor suppressor gene in breast cancer
    • DOI 10.1007/BF00666204
    • Elledge R.M. Allred D.C. The p53 tumor suppressor gene in breast cancer Breast Cancer Research and Treatment 1994 32 1 39-47 DOI 10.1007/BF00666204 5. Elledge RM, Allred DC. The p53 tumor suppressor gene in breast cancer. Breast Cancer Res Treat 1994;32:39-47. (Pubitemid 24322246)
    • (1994) Breast Cancer Research and Treatment , vol.32 , Issue.1 , pp. 39-47
    • Elledge, R.M.1    Allred, D.C.2
  • 6
    • 0031021137 scopus 로고    scopus 로고
    • P53 Protein expression, cell proliferation and steroid hormone receptors in ductal and lobular in situ carcinomas of the breast
    • DOI 10.1016/S0959-8049(96)00368-1, PII S0959804996003681
    • Rudas M. Neumayer R. Gnant M.F.X. Mittelbock M. Jakesz R. Reiner A. p53 Protein expression, cell proliferation and steroid hormone receptors in ductal and lobular in situ carcinomas of the breast European Journal of Cancer Part A 1997 33 1 39-44 DOI 10.1016/S0959-8049(96)00368-1, PII S0959804996003681 6. Rudas M, Neumayer R, Gnant MF, Mittelbock M, Jakesz R, Reiner A. p53 protein expression, cell proliferation and steroid hormone receptors in ductal and lobular in situ carcinomas of the breast. Eur J Cancer 1997;33:39-44. (Pubitemid 27099565)
    • (1997) European Journal of Cancer Part A , vol.33 , Issue.1 , pp. 39-44
    • Rudas, M.1    Neumayer, R.2    Gnant, M.F.X.3    Mittelbock, M.4    Jakesz, R.5    Reiner, A.6
  • 7
    • 0034940095 scopus 로고    scopus 로고
    • Similarity in expression of cell cycle proteins between in situ and invasive ductal breast lesions of same differentiation grade
    • DOI 10.1002/path.910
    • Mommers E.C.M. Leonhart A.M. Falix F. Michalides R. Meijer C.J.L.M. Baak J.P.A. Van Diest P.J. Similarity in expression of cell cycle proteins between in situ and invasive ductal breast lesions of same differentiation grade Journal of Pathology 2001 194 3 327-333 DOI 10.1002/path.910 7. Mommers EC, Leonhart AM, Falix F, et al. Similarity in expression of cell cycle proteins between in situ and invasive ductal breast lesions of same differentiation grade. J Pathol 2001;194:327-333 (Pubitemid 32624559)
    • (2001) Journal of Pathology , vol.194 , Issue.3 , pp. 327-333
    • Mommers, E.C.M.1    Leonhart, A.M.2    Falix, F.3    Michalides, R.4    Meijer, C.J.L.M.5    Baak, J.P.A.6    Van Diest, P.J.7
  • 8
    • 0035860140 scopus 로고    scopus 로고
    • Tumour markers in breast carcinoma correlate with grade rather than with invasiveness
    • DOI 10.1054/bjoc.2001.1995
    • Warnberg F. Nordgren H. Bergkvist L. Holmberg L. Tumour markers in breast carcinoma correlate with grade rather than with invasiveness British Journal of Cancer 2001 85 6 869-874 DOI 10.1054/bjoc.2001.1995 8. Warnberg F, Nordgren H, Bergkvist L, Holmberg L. Tumour markers in breast carcinoma correlate with grade rather than with invasiveness. Br J Cancer 2001;85:869-874 (Pubitemid 33010555)
    • (2001) British Journal of Cancer , vol.85 , Issue.6 , pp. 869-874
    • Warnberg, F.1    Nordgren, H.2    Bergkvist, L.3    Holmberg, L.4
  • 10
    • 0032475456 scopus 로고    scopus 로고
    • Immunohistochemical detection of c-erbB-2 and p53 in benign breast disease and breast cancer risk
    • Rohan T.E. Hartwick W. Miller A.B. Kandel R.A. Immunohistochemical detection of c-erbB-2 and p53 in benign breast disease and breast cancer risk Journal of the National Cancer Institute 1998 90 17 1262-1269 10. Rohan TE, Hartwick W, Miller AB, Kandel RA. Immunohistochemical detection of c-erbB-2 and p53 in benign breast disease and breast cancer risk. J Natl Cancer Inst 1998;90:1262-1269 (Pubitemid 28433470)
    • (1998) Journal of the National Cancer Institute , vol.90 , Issue.17 , pp. 1262-1269
    • Rohan, T.E.1    Hartwick, W.2    Miller, A.B.3    Kandel, R.A.4
  • 11
    • 0030810732 scopus 로고    scopus 로고
    • Relationship of a new histological categorization of ductal carcinoma in situ of the breast with size and the immunohistochemical expression of p53, c-erb B2, bcl-2, and ki-67
    • DOI 10.1016/S0046-8177(97)90014-9
    • Mack L. Kerkvliet N. Doig G. O'Malley F.P. Relationship of a new histological categorization of ductal carcinoma in situ of the breast with size and the immunohistochemical expression of p53, c-erb B2, bcl-2, and ki-67 Human Pathology 1997 28 8 974-979 DOI 10.1016/S0046-8177(97)90014-9 11. Mack L, Kerkvliet N, Doig G, O'Malley FP. Relationship of a new histological categorization of ductal carcinoma in situ of the breast with size and the immunohistochemical expression of p53, c-erb B2, bcl-2, and ki-67. Hum Pathol 1997;28:974-979 (Pubitemid 27355559)
    • (1997) Human Pathology , vol.28 , Issue.8 , pp. 974-979
    • Mack, L.1    Kerkvliet, N.2    Doig, G.3    O'Malley, F.P.4
  • 12
    • 34548421424 scopus 로고    scopus 로고
    • Predicting relapse in ductal carcinoma in situ patients: An analysis of biologic markers with long-term follow-up
    • DOI 10.1016/j.amjsurg.2007.07.002, PII S0002961007005582
    • Hieken T.J. Cheregi J. Farolan M. Kim J. Velasco J.M. Predicting relapse in ductal carcinoma in situ patients: an analysis of biologic markers with long-term follow-up American Journal of Surgery 2007 194 4 504-506 DOI 10.1016/j.amjsurg.2007.07.002, PII S0002961007005582 12. Hieken TJ, Cheregi J, Farolan M, Kim J, Velasco JM. Predicting relapse in ductal carcinoma in situ patients: an analysis of biologic markers with long-term follow-up. Am J Surg 2007;194:504-506 (Pubitemid 47361063)
    • (2007) American Journal of Surgery , vol.194 , Issue.4 , pp. 504-506
    • Hieken, T.J.1    Cheregi, J.2    Farolan, M.3    Kim, J.4    Velasco, J.M.5
  • 13
    • 34247551731 scopus 로고    scopus 로고
    • P53 Overexpression is a Predictor of Local Recurrence after Treatment for Both in situ and Invasive Ductal Carcinoma of the Breast
    • DOI 10.1016/j.jss.2006.10.045, PII S002248040600583X
    • de Roos M.A. de Bock G.H. de Vries J. van der Vegt B. Wesseling J. p53 Overexpression is a Predictor of Local Recurrence After Treatment for Both in situ and Invasive Ductal Carcinoma of the Breast Journal of Surgical Research 2007 140 1 109-114 DOI 10.1016/j.jss.2006.10.045, PII S002248040600583X 13. de Roos MA, de Bock GH, de Vries J, van der Vegt B, Wesseling J. p53 overexpression is a predictor of local recurrence after treatment for both in situ and invasive ductal carcinoma of the breast. J Surg Res 2007;140:109-114 (Pubitemid 46669545)
    • (2007) Journal of Surgical Research , vol.140 , Issue.1 , pp. 109-114
    • De Roos, M.A.1    De Bock, G.H.2    De Vries, J.3    Van Der Vegt, B.4    Wesseling, J.5
  • 14
    • 0028071555 scopus 로고
    • Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
    • Greenblatt M.S. Bennett W.P. Hollstein M. Harris C.C. Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis Cancer Research 1994 54 18 4855-4878 14. Greenblatt MS, Bennett WP, Hollstein M, Harris CC. Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res 1994;54:4855-4878 (Pubitemid 24289415)
    • (1994) Cancer Research , vol.54 , Issue.18 , pp. 4855-4878
    • Greenblatt, M.S.1    Bennett, W.P.2    Hollstein, M.3    Harris, C.C.4
  • 15
    • 0027944206 scopus 로고
    • P53 status and the efficacy of cancer therapy in vivo
    • Lowe SW, Bodis S, McClatchey A, et al. p53 status and the efficacy of cancer therapy in vivo. Science 1994;266:807-810
    • (1994) Science , vol.266 , pp. 807-810
    • Lowe, S.W.1    Bodis, S.2    McClatchey, A.3
  • 16
    • 0025633582 scopus 로고
    • Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms
    • Malkin D. Li F.P. Strong L.C. Fraumeni J.F. Jr. Nelson C.E. Kim D.H. Kassel J. Gryka M.A. Bischoff F.Z. Tainsky M.A. Friend S.H. Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms Science 1990 250 4985 1233-1238 16. Malkin D, Li FP, Strong LC, et al. Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. Science 1990;250:1233-1238 (Pubitemid 120031831)
    • (1990) Science , vol.250 , Issue.4985 , pp. 1233-1238
    • Malkin, D.1    Li, F.P.2    Strong, L.C.3    Fraumeni Jr., J.F.4    Nelson, C.E.5    Kim, D.H.6    Kassel, J.7    Gryka, M.A.8    Bischoff, F.Z.9    Tainsky, M.A.10    Friend, S.H.11
  • 17
    • 0030957152 scopus 로고    scopus 로고
    • Li-Fraumeni syndrome - A molecular and clinical review
    • Varley J.M. Evans D.G.R. Birch J.M. Li-Fraumeni syndrome - A molecular and clinical review British Journal of Cancer 1997 76 1 1-14 17. Varley JM, Evans DG, Birch JM. Li-Fraumeni syndrome - a molecular and clinical review. Br J Cancer 1997;76:1-14. (Pubitemid 27250068)
    • (1997) British Journal of Cancer , vol.76 , Issue.1 , pp. 1-14
    • Varley, J.M.1    Evans, D.G.R.2    Birch, J.M.3
  • 18
    • 0037208632 scopus 로고    scopus 로고
    • Incidence of invasive breast cancer by hormone receptor status from 1992 to 1998
    • Li CI, Daling JR, Malone KE. Incidence of invasive breast cancer by hormone receptor status from 1992 to 1998. J Clin Oncol 2003;21:28-34.
    • (2003) J Clin Oncol , vol.21 , pp. 28-34
    • Li, C.I.1    Daling, J.R.2    Malone, K.E.3
  • 19
    • 0032491774 scopus 로고    scopus 로고
    • Estrogen receptor expression in benign breast epithelium and breast cancer risk
    • Khan S.A. Rogers M.A.M. Khurana K.K. Meguid M.M. Numann P.J. Estrogen receptor expression in benign breast epithelium and breast cancer risk Journal of the National Cancer Institute 1998 90 1 37-42 19. Khan SA, Rogers MA, Khurana KK, Meguid MM, Numann PJ. Estrogen receptor expression in benign breast epithelium and breast cancer risk. J Natl Cancer Inst 1998;90:37-42. (Pubitemid 28078079)
    • (1998) Journal of the National Cancer Institute , vol.90 , Issue.1 , pp. 37-42
    • Khan, S.A.1    Rogers, M.A.M.2    Khurana, K.K.3    Meguid, M.M.4    Numann, P.J.5
  • 20
    • 13444272959 scopus 로고    scopus 로고
    • Deregulated estrogen receptor α expression in mammary epithelial cells of transgenic mice results in the development of ductal carcinoma in situ
    • Frech MS, Halama ED, Tilli MT, et al. Deregulated estrogen receptor α expression in mammary epithelial cells of transgenic mice results in the development of ductal carcinoma in situ. Cancer Res 2005;65:681-685
    • (2005) Cancer Res , vol.65 , pp. 681-685
    • Frech, M.S.1    Halama, E.D.2    Tilli, M.T.3
  • 21
    • 0026356489 scopus 로고
    • The epidemiology of breast cancer
    • Kelsey JL, Gammon MD. The epidemiology of breast cancer. CA Cancer J Clin 1991;41:146-165
    • (1991) CA Cancer J Clin , vol.41 , pp. 146-165
    • Kelsey, J.L.1    Gammon, M.D.2
  • 22
    • 0036362083 scopus 로고    scopus 로고
    • Epidemiology of endocrine-related risk factors for breast cancer
    • DOI 10.1023/A:1015714305420
    • Bernstein L. Epidemiology of endocrine-related risk factors for breast cancer Journal of Mammary Gland Biology and Neoplasia 2002 7 1 3-15 DOI 10.1023/A:1015714305420 22. Bernstein L. Epidemiology of endocrine-related risk factors for breast cancer. J Mammary Gland Biol Neoplasia 2002;7:3-15. (Pubitemid 38420778)
    • (2002) Journal of Mammary Gland Biology and Neoplasia , vol.7 , Issue.1 , pp. 3-15
    • Bernstein, L.1
  • 24
    • 0141988721 scopus 로고    scopus 로고
    • P53 function is required for hormone-mediated protection of mouse mammary tumorigenesis
    • Medina D, Kittrell FS. p53 function is required for hormone-mediated protection of mouse mammary tumorigenesis. Cancer Res 2003;63:6140-6143
    • (2003) Cancer Res , vol.63 , pp. 6140-6143
    • Medina, D.1    Kittrell, F.S.2
  • 25
    • 0035940463 scopus 로고    scopus 로고
    • P53 is a potential mediator of pregnancy and hormone-induced resistance to mammary carcinogenesis
    • Sivaraman L, Conneely OM, Medina D, O'Malley B. p53 is a potential mediator of pregnancy and hormone-induced resistance to mammary carcinogenesis. Proc Natl Acad Sci U S A 2001;98:12379-12384
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 12379-12384
    • Sivaraman, L.1    Conneely, O.M.2    Medina, D.3    O'Malley, B.4
  • 26
    • 55749090657 scopus 로고    scopus 로고
    • Estrogen and progesterone induce persistent increases in p53-dependent apoptosis and suppress mammary tumors in BALB/c-Trp53+/- Mice
    • Dunphy KA, Blackburn AC, Yan H, O'Connell LR, Jerry DJ. Estrogen and progesterone induce persistent increases in p53-dependent apoptosis and suppress mammary tumors in BALB/c-Trp53+/- mice. Breast Cancer Res 2008;10:R43.
    • (2008) Breast Cancer Res , vol.10
    • Dunphy, K.A.1    Blackburn, A.C.2    Yan, H.3    O'Connell, L.R.4    Jerry, D.J.5
  • 27
    • 12344308462 scopus 로고    scopus 로고
    • Estrogen receptor-negative breast carcinomas: A review of morphology and immunophenotypical analysis
    • Putti TC, El-Rehim DM, Rakha EA, et al. Estrogen receptor-negative breast carcinomas: a review of morphology and immunophenotypical analysis. Mod Pathol 2005;18:26-35.
    • (2005) Mod Pathol , vol.18 , pp. 26-35
    • Putti, T.C.1    El-Rehim, D.M.2    Rakha, E.A.3
  • 28
    • 0036615473 scopus 로고    scopus 로고
    • Biological and genetic properties of the p53 null preneoplastic mammary epithelium
    • Medina D, Kittrell FS, Shepard A, et al. Biological and genetic properties of the p53 null preneoplastic mammary epithelium. FASEB J 2002;16:881-883
    • (2002) FASEB J , vol.16 , pp. 881-883
    • Medina, D.1    Kittrell, F.S.2    Shepard, A.3
  • 29
    • 0037374020 scopus 로고    scopus 로고
    • Hormone dependence in premalignant mammary progression
    • Medina D. Kittrell F.S. Shepard A. Contreras A. Rosen J.M. Lydon J. Hormone dependence in premalignant mammary progression Cancer Research 2003 63 5 1067-1072 29. Medina D, Kittrell FS, Shepard A, Contreras A, Rosen JM, Lydon J. Hormone dependence in premalignant mammary progression. Cancer Res 2003;63:1067-1072 (Pubitemid 36278440)
    • (2003) Cancer Research , vol.63 , Issue.5 , pp. 1067-1072
    • Medina, D.1    Kittrell, F.S.2    Shepard, A.3    Contreras, A.4    Rosen, J.M.5    Lydon, J.6
  • 30
    • 68949093614 scopus 로고    scopus 로고
    • KLF4 suppresses estrogen-dependent breast cancer growth by inhibiting the transcriptional activity of ERα
    • Akaogi K, Nakajima Y, Ito I, et al. KLF4 suppresses estrogen-dependent breast cancer growth by inhibiting the transcriptional activity of ERα. Oncogene 2009;28:2894-2902
    • (2009) Oncogene , vol.28 , pp. 2894-2902
    • Akaogi, K.1    Nakajima, Y.2    Ito, I.3
  • 31
    • 65949102326 scopus 로고    scopus 로고
    • Transcriptional regulation of estrogen receptor-α by p53 in human breast cancer cells
    • Shirley SH, Rundhaug JE, Tian J, et al. Transcriptional regulation of estrogen receptor-α by p53 in human breast cancer cells. Cancer Res 2009;69:3405-3414
    • (2009) Cancer Res , vol.69 , pp. 3405-3414
    • Shirley, S.H.1    Rundhaug, J.E.2    Tian, J.3
  • 32
    • 34547134493 scopus 로고    scopus 로고
    • Src promotes estrogen-dependent estrogen receptor α proteolysis in human breast cancer
    • DOI 10.1172/JCI21739
    • Chu I. Arnaout A. Loiseau S. Sun J. Seth A. McMahon C. Chun K. Hennessy B. Mills G.B. Nawaz Z. Slingerland J.M. Src promotes estrogen-dependent estrogen receptor α proteolysis in human breast cancer Journal of Clinical Investigation 2007 117 8 2205-2215 http://www.jci.org/cgi/reprint/117/8/2205 DOI 10.1172/JCI21739 32. Chu I, Arnaout A, Loiseau S, et al. Src promotes estrogen-dependent estrogen receptor α proteolysis in human breast cancer. J Clin Invest 2007;117:2205-2215 (Pubitemid 47219565)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.8 , pp. 2205-2215
    • Chu, I.1    Arnaout, A.2    Loiseau, S.3    Sun, J.4    Seth, A.5    McMahon, C.6    Chun, K.7    Hennessy, B.8    Mills, G.B.9    Nawaz, Z.10    Slingerland, J.M.11
  • 33
    • 66349124406 scopus 로고    scopus 로고
    • P53 suppresses Src-induced podosome and rosette formation and cellular invasiveness through the upregulation of caldesmon
    • Mukhopadhyay UK, Eves R, Jia L, Mooney P, Mak AS. p53 suppresses Src-induced podosome and rosette formation and cellular invasiveness through the upregulation of caldesmon. Mol Cell Biol 2009;29:3088-3098
    • (2009) Mol Cell Biol , vol.29 , pp. 3088-3098
    • Mukhopadhyay, U.K.1    Eves, R.2    Jia, L.3    Mooney, P.4    Mak, A.S.5
  • 34
    • 0033028043 scopus 로고    scopus 로고
    • The role of p53 in tumour suppression: Lessons from mouse models
    • DOI 10.1007/s000180050269
    • Attardi L.D. Jacks T. The role of p53 in tumour suppression: Lessons from mouse models Cellular and Molecular Life Sciences 1999 55 1 48-63 DOI 10.1007/s000180050269 34. Attardi LD, Jacks T. The role of p53 in tumour suppression: lessons from mouse models. Cell Mol Life Sci 1999;55:48-63. (Pubitemid 29077854)
    • (1999) Cellular and Molecular Life Sciences , vol.55 , Issue.1 , pp. 48-63
    • Attardi, L.D.1    Jacks, T.2
  • 35
    • 0030812202 scopus 로고    scopus 로고
    • Absence of p53 in a mouse mammary tumor model promotes tumor cell proliferation without affecting apoptosis
    • Jones J.M. Attardi L. Godley L.A. Laucirica R. Medina D. Jacks T. Varmus H.E. Donehower L.A. Absence of p53 in a mouse mammary tumor model promotes tumor cell proliferation without affecting apoptosis Cell Growth and Differentiation 1997 8 8 829-838 35. Jones JM, Attardi L, Godley LA, et al. Absence of p53 in a mouse mammary tumor model promotes tumor cell proliferation without affecting apoptosis. Cell Growth Differ 1997;8:829-838 (Pubitemid 27355456)
    • (1997) Cell Growth and Differentiation , vol.8 , Issue.8 , pp. 829-838
    • Jones, J.M.1    Attardi, L.2    Godley, L.A.3    Laucirica, R.4    Medina, D.5    Jacks, T.6    Varmus, H.E.7    Donehower, L.A.8
  • 36
    • 34547121428 scopus 로고    scopus 로고
    • Mammary tumor modifiers in BALB/cJ mice heterozygous for p53
    • DOI 10.1007/s00335-007-9028-2
    • Koch J.G. Gu X. Han Y. El-Naggar A.K. Olson M.V. Medina D. Jerry D.J. Blackburn A.C. Peltz G. Amos C.I. Lozano G. Mammary tumor modifiers in BALB/cJ mice heterozygous for p53 Mammalian Genome 2007 18 5 300-309 DOI 10.1007/s00335-007-9028-2 36. Koch JG, Gu X, Han Y, et al. Mammary tumor modifiers in BALB/cJ mice heterozygous for p53. Mamm Genome 2007;18:300-309 (Pubitemid 47106845)
    • (2007) Mammalian Genome , vol.18 , Issue.5 , pp. 300-309
    • Koch, J.G.1    Gu, X.2    Han, Y.3    El-Naggar, A.K.4    Olson, M.V.5    Medina, D.6    Jerry, D.J.7    Blackburn, A.C.8    Peltz, G.9    Amos, C.I.10    Lozano, G.11
  • 37
    • 0036187113 scopus 로고    scopus 로고
    • A novel doxycycline-inducible system for the transgenic analysis of mammary gland biology
    • Gunther EJ, Belka GK, Wertheim GB, et al. A novel doxycycline-inducible system for the transgenic analysis of mammary gland biology. FASEB J 2002;16:283-292
    • (2002) FASEB J , vol.16 , pp. 283-292
    • Gunther, E.J.1    Belka, G.K.2    Wertheim, G.B.3
  • 38
    • 0036702774 scopus 로고    scopus 로고
    • Conditional over-expression of estrogen receptor alpha in a transgenic mouse model
    • DOI 10.1023/A:1016376100186
    • Hruska K.S. Tilli M.T. Ren S. Cotarla I. Kwong T. Li M. Fondell J.D. Hewitt J.A. Koos R.D. Furth P.A. Flaws J.A. Conditional over-expression of estrogen receptor alpha in a transgenic mouse model Transgenic Research 2002 11 4 361-372 DOI 10.1023/A:1016376100186 38. Hruska KS, Tilli MT, Ren S, et al. Conditional over-expression of estrogen receptor α in a transgenic mouse model. Transgenic Res 2002;11:361-372 (Pubitemid 35301747)
    • (2002) Transgenic Research , vol.11 , Issue.4 , pp. 361-372
    • Hruska, K.S.1    Tilli, M.T.2    Ren, S.3    Cotarla, I.4    Kwong, T.5    Li, M.6    Fondell, J.D.7    Hewitt, J.A.8    Koos, R.D.9    Furth, P.A.10    Flaws, J.A.11
  • 39
    • 0028118111 scopus 로고
    • Tumor spectrum analysis in p53-mutant mice
    • DOI 10.1016/S0960-9822(00)00002-6
    • Jacks T. Remington L. Williams B.O. Schmitt E.M. Halachmi S. Bronson R.T. Weinberg R.A. Tumor spectrum analysis in p53-mutant mice Current Biology 1994 4 1 1-7 DOI 10.1016/S0960-9822(00)00002-6 39. Jacks T, Remington L, Williams BO, et al. Tumor spectrum analysis in p53-mutant mice. Curr Biol 1994;4:1-7. (Pubitemid 2027671)
    • (1994) Current Biology , vol.4 , Issue.1 , pp. 1-7
    • Jacks, T.1    Remington, L.2    Williams, B.O.3    Schmitt, E.M.4    Halachmi, S.5    Bronson, R.T.6    Weinberg, R.A.7
  • 40
    • 0142182119 scopus 로고    scopus 로고
    • Introduction of estrogen receptor-α into the tTA/TAg conditional mouse model precipitates the development of estrogen-responsive mammary adenocarcinoma
    • Tilli MT, Frech MS, Steed ME, et al. Introduction of estrogen receptor-α into the tTA/TAg conditional mouse model precipitates the development of estrogen-responsive mammary adenocarcinoma. Am J Pathol 2003;163:1713-1719
    • (2003) Am J Pathol , vol.163 , pp. 1713-1719
    • Tilli, M.T.1    Frech, M.S.2    Steed, M.E.3
  • 41
    • 3042711375 scopus 로고    scopus 로고
    • Links between apoptosis, proliferation and the cell cycle
    • Alenzi F.Q.B. Links between apoptosis, proliferation and the cell cycle British Journal of Biomedical Science 2004 61 2 99-102 41. Alenzi FQ. Links between apoptosis, proliferation and the cell cycle. Br J Biomed Sci 2004;61:99-102. (Pubitemid 38879538)
    • (2004) British Journal of Biomedical Science , vol.61 , Issue.2 , pp. 99-102
    • Alenzi, F.Q.B.1
  • 42
    • 63649099281 scopus 로고    scopus 로고
    • Novel actions of estrogen to promote proliferation: Integration of cytoplasmic and nuclear pathways
    • Fox EM, Andrade J, Shupnik MA. Novel actions of estrogen to promote proliferation: integration of cytoplasmic and nuclear pathways. Steroids 2009;74:622-627
    • (2009) Steroids , vol.74 , pp. 622-627
    • Fox, E.M.1    Andrade, J.2    Ma, S.3
  • 43
    • 34547209343 scopus 로고    scopus 로고
    • Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance
    • McCubrey JA, Steelman LS, Chappell WH, et al. Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance. Biochim Biophys Acta 2007;1773:1263-1284
    • (2007) Biochim Biophys Acta , vol.1773 , pp. 1263-1284
    • McCubrey, J.A.1    Steelman, L.S.2    Chappell, W.H.3
  • 44
    • 53849147183 scopus 로고    scopus 로고
    • Post-translational regulation of the tumor suppressor p27(KIP1)
    • Vervoorts J, Luscher B. Post-translational regulation of the tumor suppressor p27(KIP1). Cell Mol Life Sci 2008;65:3255-3264
    • (2008) Cell Mol Life Sci , vol.65 , pp. 3255-3264
    • Vervoorts, J.1    Luscher, B.2
  • 45
    • 36349006988 scopus 로고    scopus 로고
    • Relationship between p53 and p27 expression following HER2 signaling
    • DOI 10.1016/j.breast.2007.05.007, PII S0960977607001063
    • Casalini P. Iorio M.V. Berno V. Bergamaschi A. Borresen Dale A.-L. Gasparini P. Orlandi R. Casati B. Tagliabue E. Menard S. Relationship between p53 and p27 expression following HER2 signaling Breast 2007 16 6 597-605 DOI 10.1016/j.breast.2007.05.007, PII S0960977607001063 45. Casalini P, Iorio MV, Berno V, et al. Relationship between p53 and p27 expression following HER2 signaling. Breast 2007;16:597-605. (Pubitemid 350154449)
    • (2007) Breast , vol.16 , Issue.6 , pp. 597-605
    • Casalini, P.1    Iorio, M.V.2    Berno, V.3    Bergamaschi, A.4    Borresen Dale, A.-L.5    Gasparini, P.6    Orlandi, R.7    Casati, B.8    Tagliabue, E.9    Menard, S.10
  • 46
    • 0035110997 scopus 로고    scopus 로고
    • Kip1 and cyclin D1 proteins in breast ductal carcinoma in situ: Relation with clinicopathologic characteristics and with p53 expression and estrogen receptor status
    • DOI 10.1046/j.1440-1827.2001.01173.x
    • Kip1 and cyclin D1 proteins in breast ductal carcinoma in situ: Relation with clinicopathologic characteristics and with p53 expression and estrogen receptor status Pathology International 2001 51 2 94-99 DOI 10.1046/j.1440-1827.2001.01173.x 46. Oh YL, Choi JS, Song SY, et al. Expression of p21Waf1, p27Kip1 and cyclin D1 proteins in breast ductal carcinoma in situ: relation with clinicopathologic characteristics and with p53 expression and estrogen receptor status. Pathol Int 2001;51:94-99 (Pubitemid 32174734)
    • (2001) Pathology International , vol.51 , Issue.2 , pp. 94-99
    • Oh, Y.L.1    Choi, J.S.2    Song, S.-Y.3    Ko, Y.H.4    Han, B.-K.5    Nam, S.-J.6    Yang, J.-H.7
  • 47
    • 0034092911 scopus 로고    scopus 로고
    • Regulation of the Cdk inhibitor p27 and its deregulation in cancer
    • DOI 10.1002/(SICI)1097-4652(200004)183:1<10::AID-JCP2>3.0.CO;2-I
    • Slingerland J. Pagano M. Regulation of the Cdk inhibitor p27 and its deregulation in cancer Journal of Cellular Physiology 2000 183 1 10-17 DOI 10.1002/(SICI)1097-4652(200004)183:1<10::AID-JCP2>3.0.CO;2-I 47. Slingerland J, Pagano M. Regulation of the cdk inhibitor p27 and its deregulation in cancer. J Cell Physiol 2000;183:10-17 (Pubitemid 30130220)
    • (2000) Journal of Cellular Physiology , vol.183 , Issue.1 , pp. 10-17
    • Slingerland, J.1    Pagano, M.2
  • 48
    • 33846268807 scopus 로고    scopus 로고
    • P27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2 and p27 proteolysis
    • Chu I, Sun J, Arnaout A, et al. p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2 and p27 proteolysis. Cell 2007;128:281-294
    • (2007) Cell , vol.128 , pp. 281-294
    • Chu, I.1    Sun, J.2    Arnaout, A.3
  • 49
    • 0023576146 scopus 로고
    • Frequency and distribution of estrogen receptor-positive cells in normal, nonlactating human breast tissue
    • Petersen OW, Hoyer PE, van Deurs B. Frequency and distribution of estrogen receptor-positive cells in normal, nonlactating human breast tissue. Cancer Res 1987;47:5748-5751
    • (1987) Cancer Res , vol.47 , pp. 5748-5751
    • Petersen, O.W.1    Hoyer, P.E.2    Van Deurs, B.3
  • 50
    • 34347262483 scopus 로고    scopus 로고
    • Differential regulation of estrogen receptor α turnover and transactivation by Mdm2 and stress-inducing agents
    • DOI 10.1158/0008-5472.CAN-07-0967
    • Duong V. Boulle N. Daujat S. Chauvet J. Bonnet S. Neel H. Cavailles V. Differential regulation of estrogen receptor α turnover and transactivation by Mdm2 and stress-inducing agents Cancer Research 2007 67 11 5513-5521 http://cancerres.aacrjournals.org/cgi/reprint/67/11/5513 DOI 10.1158/0008-5472.CAN-07-0967 50. Duong V, Boulle N, Daujat S, et al. Differential regulation of estrogen receptor α turnover and transactivation by Mdm2 and stress-inducing agents. Cancer Res 2007;67:5513-5521 (Pubitemid 46997293)
    • (2007) Cancer Research , vol.67 , Issue.11 , pp. 5513-5521
    • Duong, V.1    Boulle, N.2    Daujat, S.3    Chauvet, J.4    Bonnet, S.5    Neel, H.6    Cavailles, V.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.