Effect of ginkgolide B on striatal extracellular amino acids in middle cerebral artery occluded rats

Journal of Ethnopharmacology

Volumn 136, Issue 1, 2011, Pages 117-122

  Yang, Zan Zhang ^a,b   Li, Jing ^c   Li, Shan Xue ^a   Feng, Wei ^a   Wang, Hao ^a  

^a Xingtai Ophthalmology Hospital   (China)

^b Key Laboratory of Ministry of Education of China for Xinjiang Phytomedicine Resources   (China)

^c Department of Pediatrics   (China)

Author keywords

Brain microdialysis; Excitatory amino acids; Ginkgolide B; Inhibitory amino acids; Middle cerebral artery occlusion

Indexed keywords

4 AMINOBUTYRIC ACID; AMINO ACID; ASPARTIC ACID; GINKGOLIDE B; GLUTAMIC ACID; GLYCINE; SODIUM CHLORIDE; THROMBOCYTE ACTIVATING FACTOR ANTAGONIST; TRIPHENYLTETRAZOLIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INFARCTION; BRAIN ISCHEMIA; BRAIN SLICE; CALCULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; EXCITOTOXICITY; GINKGO BILOBA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VIVO STUDY; MALE; MICRODIALYSIS; MIDDLE CEREBRAL ARTERY OCCLUSION; NEOSTRIATUM; NONHUMAN; RAT; STRIATE CORTEX;

AMINO ACIDS; ANIMALS; ASPARTIC ACID; BRAIN ISCHEMIA; CORPUS STRIATUM; GAMMA-AMINOBUTYRIC ACID; GINKGO BILOBA; GINKGOLIDES; GLUTAMIC ACID; GLYCINE; INFARCTION, MIDDLE CEREBRAL ARTERY; LACTONES; MALE; PHYTOTHERAPY; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY;

ANIMALIA; GINKGO BILOBA; RATTUS;

EID: 79958124070     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2011.04.027     Document Type: Article

References (66)

1. Ahlemeyer, B., Krieglstein, J., 2003. Pharmacological studies supporting the therapeutic use of Ginkgo biloba extract for Alzheimer's disease. Pharmacopsychiatry 36, S8-S14. (Pubitemid 37047003)
2. Akiba, S., Kawauchi, T., Oka, T., Hashizume, T., Sato, T., 1998. Inhibitory effect of the leaf extract of Ginkgo biloba L. on oxidative stress-induced platelet aggregation. Biochemistry and Molecular Biology International 46, 1243-1248. (Pubitemid 29027182)
3. Alessia, M., Leonardo, P., Claudia, C., et al., 1999. Striatal outflow of adenosine, excitatory amino acids, γ-aminobutyric acid, and taurine in awake freely moving rats after middle cerebral artery occlusion correlations with neurological deficit and histopathological damage. Stroke 30, 2448-2455.
4. Aronowski, J., Strong, R., Grotta, J.C., 1997. Reperfusion injury: demonstration of brain damage produced by reperfusion after transient focal ischemia in rats. Journal of Cerebral Blood Flow and Metabolism 17, 1048-1056. (Pubitemid 27459332)
5. Baker, A.J., Zornow, M.H., Grafe, M.R., Scheller, M.S., Skilling, S.R., Smullin, D.H., Larson, A.A., 1991. Hypothermia prevents ischemia-induced increases in hippocampal glycine concentrations in rabbits. Stroke 22, 666-673.
6. Benveniste, H., Drejer, J., Schousboe, A., Diemer, N.H., 1984. Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis. Journal of Neurochemistry 43, 1369-1374. (Pubitemid 15205893)
7. Bezzi, P., Carmignoto, G., Pasti, L., Vesce, S., Rossi, D., Rizzini, B.L., Pozzan, T., Volterra, A., 1998. Prostaglandins stimulate calcium-dependent glutamate release in astrocytes. Nature 391, 281-285. (Pubitemid 28099014)
8. Bogaert, L., Scheller, D., Moonen, J., Sarre, S., Smolders, I., Ebing, G., Michotte, Y., 2000. Neurochemical changes and laser Doppler flowmetry in the endothelin-1 rat model for focal cerebral ischemia. Brain Research 887, 266-275. (Pubitemid 32008048)
9. Butcher, S.P., Bullock, R., Graham, D.I., McCulloch, J., 1990. Correlation between amino acid release and neuropathologic outcome in rat brain following middle cerebral artery occlusion. Stroke 21, 1727-1733.
10. Carmichael, S.T., 2005. Rodent models of focal stroke: size, mechanism, and purpose. NeuroRx 2, 396-409. (Pubitemid 41444874)
11. Centonze, D., Saule, E., Pisani, A., Bernardiand, G., Calabresi, P., 2001. Adenosine-mediated inhibition of striatal GABA ergic synaptic transmission during in vitro ischaemia. Brain 124, 1855-1865. (Pubitemid 32845446)
12. Chan, P.H., 2001. Reactive oxygen radicals in signaling and damage in the ischemic brain. Journal of Cerebral Blood Flow and Metabolism 21, 2-14. (Pubitemid 32036708)
13. Choi, D.W., Koh, J.Y., Peters, S., 1988. Pharmacology of glutamate neurotoxicity in cortical cell culture: attenuation by NMDA antagonists. Journal of Neuroscience 8, 185-196.
14. Clark, W.M., Rinker, L.G., Lessov, N.S., Lowery, S.L., Cipolla, M.J., 2001. Efficacy of antioxidant therapies in transient focal ischemia in mice. Stroke 32, 1000-1004. (Pubitemid 32285174)
15. Dalkara, T., Erdemli, G., Barum, S., Onur, R., 1992. Glycine is required for NMDA receptor activation: electrophysiological evidence from intact rat hippocampus. Brain Research 576, 197-202.
16. Deng, X.M., Li, J.B., Liu, S.X., Zhu, C., 2004. Changes in amino acid neurotransmitters during cerebral ischemia and reperfusion in awake rats. Chinese Journal of Pathophysiology 20, 660-663.
17. Desquand, S., Touvay, C., Randon, J., Lagente, V., Vilain, B., Maridonneau-Parini, I., Etienne, A., Lefort, J., Braquet, P., Vargaftig, B.B., 1986. Interference of BN 52021 (ginkgolide B) with the bronchopulmonary effects of PAF-acether in the guinea-pig. European Journal of Pharmacology 127, 83-95. (Pubitemid 16023613)
18. Dohmen, C., Kumura, E., Rosner, G., Heiss, W.D., Graf, R., 2005. Extracellular correlates of glutamate toxicity in short-term cerebral ischemia and reperfusion: a direct in vivo comparison between white and gray matter. Brain Research 1037, 43-51. (Pubitemid 40362380)
19. Drejer, J., Benveniste, H., Diemer, N.H., Schousboe, A., 1985. Cellular origin of ischemia-induced glutamate release from brain tissue in vivo and in vitro. Journal of Neurochemistry 45, 145-151. (Pubitemid 15046087)
20. Drieu, K., 1988. In: Fünfgeld, E.W. (Ed.), Rökan Ginkgo biloba: Recent Results in Pharmacology and Clinic. Springer-Verlag, Berlin, pp. 32-36.
21. Globus, M.Y., Ginsberg, M.D., Busto, R., 1991. Excitotoxic index: a biochemical marker of selective vulnerability. Neuroscience Letters 127, 39-42.
22. Green, A.R., Hainsworth, A.H., Jackson, D.M., 2000. GABA potentiation: a logical pharmacological approach for the treatment of acute ischemic stroke. Neuropharmacology 39, 1483-1494. (Pubitemid 30330866)
23. Hallenbeck, J.M., Dutka, A.J., 1990. Background review and current concepts of reperfusion injury. Archives of Neurology 47, 1245-1254. (Pubitemid 20381010)
24. Heurteaux, C., Laigle, C., Blondeau, N., Jarretou, G., Lazdunski, M., 2006. Alpha-linolenic acid and riluzole treatment confer cerebral protection and improve survival after focal brain ischemia. Neuroscience 137, 241-251. (Pubitemid 43031491)
25. Hossmann, K.A., 1994. Glutamate-mediated injury in focal cerebral ischemia: the excitation hypothesis revisited. Brain Pathology 4, 22-36.
26. Huang, J.Y., Sun, J.N., Mei, S.C., 2008. Protective effects of ginkgolide B on cerebral ischemia reperfusion injury in rats. Chinese Pharmacological Bulletin 24, 269-272.
27. Itil, T., Martorano, D., 1995. Natural substances in psychiatry (Ginkgo biloba in dementia). Psychopharmacology Bulletin 31, 147-158.
28. Jia, J., Hu, Y.S., Wu, Y., et al., 2009. Pre-ischemic treadmill training affects glutamate and gamma aminobutyric acid levels in the striatal dialysate of a rat model of cerebral ischemia. Life Sciences 84, 505-511.
29. Katchman, A.N., Hershkowitz, N., 1993. Early anoxia-induced vesicular glutamate release results from mobilization of calcium from intracellular stores. Journal of Neurophysiology 70, 1-7. (Pubitemid 23220294)
30. Kleckner, N.W., Dingledine, R., 1988. Requirement for glycine in activation of NMDA-receptors expressed in Xenopus oocytes. Science 241, 835-837.
31. Kuroda, S., Siesjo, B.K., 1997. Reperfusion damage following focal ischemia: pathophysiology and therapeutic windows. Joural of Clinical Neuroscience 4, 199-212. (Pubitemid 27250687)
32. Leach, M.J., Swan, J.H., Eisenthal, D., Dopson, M., Nobbs, M., 1993. BW619C89, a glutamate release inhibitor, protects against focal cerebral ischemia damage. Stroke 24, 1063-1067. (Pubitemid 23201467)
33. Li, S.Q., Zhang, Y., Yang, L.J., 2007. Improving effect of Ginkgolide B on mitochondrial respiration of ischemic neuron after cerebral thrombosis in tree shrews. Chinese Medical Journal 120, 1529-1533. (Pubitemid 47496590)
34. Liu, Y.G., Li, F.J., Wang, J., Wang, X.D., 2010. Effects of Ginkgolide B on inflammation induced by cerebral ischemia-reperfusion in rats. Zhong Yao Cai 33, 578-580.
35. Liou, K.T., Shen, Y.C., Chen, C.F., Tsao, C.M., Tsai, S.K., 2003. Honokiol protects rat brain from focal cerebral ischemia-reperfusion injury by inhibiting neutrophil infiltration and reactive oxygen species production. Brain Research 992, 159-166.
36. Ling, N.S., Pi, Z.F., Du, R.H., Zhang, X.D., Geng, T., 2002. Study on the antioxidative effect of ginkgolide B to the ischemia-reperfused rabbit. Journal of Harbin University of Commerce Natural Sciences Edition 18, 83-85.
37. Masaya, O., Shigeo, K., Taku, S., et al., 2007. Direct correlation between ischemic injury and extracellular glycine concentration in mice with genetically altered activities of the glycine cleavage multienzyme system. Stroke 38, 2157-2164.
38. + pump failure as studied by in vivo 31 P and 23Na nuclear magnetic resonance spectroscopy. Journal of Cerebral Blood Flow and Metabolism 8, 16-23.
39. Ohtani, K., Tanaka, H., Yasuda, H., Maruoka, Y., Kawabe, A., Nakamura, M., 2000. Blocking of the glycine-binding site ofNMDAreceptors prevents the progression of ischemic pathology induced by bilateral carotid artery occlusion in spontaneously hypertensive rats. Brain Research 871, 311-318. (Pubitemid 30433882)
40. Paul, F.S., Karyn, M., Cynthia, L.D., 1996. The neuroprotective properties of the Ginkgo biloba leaf: a review of the possible relationship to platelet-activating factor (PAF). Journal of Ethnopharmacology 50, 131-139.
41. Paxinos, G., Watson, C., 1998. The Rat Brain in Stereotaxic Coordinates, 4th ed. Academic Press, New York.
42. Pierre, B., David, H., 1991. Ethnopharmacology and the development of natural PAF antagonists as therapeutic agents. Journal of Ethnopharmacology 32, 135-139.
43. Qin, B., Zhang, G.B., Chen, D.Y., Xu, M., Li, A.H., 2005. Protective effects of ginkgolide B on neuron injury induced by cerebral ischemia/reperfusion. Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care 12, 17-20.
44. Rothman, S.M., Olney, J.W., 1987. Excitotoxicity and the NMDA receptor. Trends in Neurosciences 10, 299-302. (Pubitemid 17090077)
45. Saleem, S., Zhuang, H., Biswal, S., Christen, Y., Doré, S., 2008. Ginkgo biloba extract neuroprotective action is dependent on heme oxygenase 1 in ischemic reperfusion brain injury. Stroke 39, 3389-3396.
46. 2+-independent release of glutamate during anoxia in isolated nerve terminals (synaptosomes). Journal of Neurochemistry 50, 1322-1324.
47. Saransaari, P., Oja, S.S., 2001. Characteristics of hippocampal glycine release in cell-damaging conditions in the adult and developing mouse. Neurochemical Research 26, 845-852. (Pubitemid 32845978)
48. Saransaari, P., Oja, S.S., 2008. Characteristics of GABA release induced by free radicals in mouse hippocampal slices. Neurochemical Research 33, 384-393. (Pubitemid 351230438)
49. Schwartz-Bloom, R.D., Miller, K.A., Evenson, D.A., Crain, B.J., Nadler, J.V., 2000. Benzodiazepines protect hippocampal neurons from degeneration after transient cerebral ischemia: an ultrastructural study. Neuroscience 98, 471-484. (Pubitemid 30408167)
50. Small, D.L., Buchan, A.M., 1996. Mechanisms of cerebral ischemia: intracellular cascades and therapeutic interventions. Journal of cardiothoracic and Vascular Anesthesia 10, 139-146. (Pubitemid 26051613)
51. Sonata, T., Jurga, B., Daiva, M., Valdas, J., Arunas, S., Adolfas, T., 2007. Effect of Ginkgo biloba extract on the rat heart mitochondrial function. Journal of Ethnopharmacology 111, 512-516.
52. Su, S.Y., Hsieh, C.L., Wu, S.L., Cheng, W.Y., Li, C.C., Lo, H.Y., Ho, T.Y., Hsiang, C.Y., 2009. Transcriptomic analysis of EGb 761-regulated neuroactive receptor pathway in vivo. Journal of Ethnopharmacology 123, 68-73.
53. Vargaftig, B.B., Lefort, J., Chignard, M., Benveniste, J., 1980. Platelet-activating factor induces a platelet-dependent bronchoconstriction unrelated to the formation of prostaglandin derivatives. European Journal of Pharmacology 65, 185-192. (Pubitemid 10058073)
54. Vargaftig, B.B., Benveniste, J., 1983. Platelet-activating factor today. Trends in Pharmacological Sciences 4, 341-343.
55. Wang, Q., Sun, A.Y., Simonyi, A., et al., 2007. Ethanol preconditioning protects against ischemia/reperfusion-induced brain damage: role of NADPH oxidase-derived ROS. Free Radical Biology and Medicine 43, 1048-1060. (Pubitemid 47302653)
56. Wang, X., Shimizu, S.M., Moskowitz, M.A., Newcomb, R., Lo, E.H., 2001. Profiles of glutamate and GABA efflux in core versus peripheral zones of focal cerebral ischemia in mice. Neuroscience Letters 313, 121-124. (Pubitemid 33022585)
57. Wayne, M.C., Lisa, G.R., Nikola, S.L., Stuart, L.L., Marilyn, J.C., 2001. Efficacy of antioxidant therapies in transient focal ischemia in mice. Stroke 32, 1000-1004.
58. Xiang, J., Tang, Y.P., Cai, D.F., 2010. Glutamate receptor-independent calcium toxicity pathways in acute ischemic brain injury. Chinese Journal of Pathophysiology 26, 1124-1128.
59. Xiao, Z.Y., Sun, C.K., Xiao, X.W., Lin, Y.Z., Li, S., Ma, H., Song, G.R., Cheng, R., 2006. Effects of Ginkgo biloba extract against excitotoxicity induced by NMDA receptors and mechanism thereof. Zhonghua Yi Xue Za Zhi 86, 2479-2484. (Pubitemid 44829031)
60. Xu, J., Sun, C.K., Ma, H., Wang, L., Zhang, J., Zhang, Y.M., Wu, L.X., 2010. Neuroprotective effect of extract of Ginkgo biloba against excitotoxicity compared with ginkgolide B in neuron cell of rat. China Journal of Chinese Material Medica 35, 114-117.
61. Yun, B.Y., Ryoo, I.J., Kim, J.S., Kim, C.J., Yoo, I.D., 2001. Neuroprotectins A and B, bicyclohexapeptides protecting chick telencephalic neuronal cells from excitotoxicity. The Journal of Antibiotics 54, 1013-1018.
62. Zafar, A.M., Manjeet, S., Sharma, P.L., 2011. Neuroprotective effect of Momordica charantia in global cerebral ischemia and reperfusion induced neuronal damage in diabetic mice. Journal of Ethnopharmacology 133, 729-734.
63. Zea-longa, E.L., Weinstein, P.R., Carlson, S., Cummins, R., 1989. Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 20, 84-91. (Pubitemid 19040218)
64. Zhang, S.F., Huang, J.Y., Wang, J., 2006a. Effect of ginkgolide B injection on rat cerebral ischemia reperfusion lesion. Journal of Beijing University of Traditional Chinese Medicine 29, 836-839.
65. Zhang, S.F., Jia, Z.H., Wu, J.Y., 2006b. Protective effect of ginkgolide B injection on focal cerebral ischemia in rats. Journal of China-Japan Friendship Hospital 20, 229-231.
66. Zhang, Y.Y., Yu, Q.H., You, S., Sheng, L., Sun, P., 2001. Protective effect of total ginkgolides on cerebral ischemia in mice and rats. Chinese Pharmacological Bulletin 17, 667-669. (Pubitemid 34051790)