Descending facilitatory pathways from the rostroventromedial medulla mediate naloxone-precipitated withdrawal in morphine-dependent rats

Journal of Pain

Volumn 12, Issue 6, 2011, Pages 667-676

  Vera Portocarrero, Louis P ^a   Ossipov, Michael H ^a   Lai, Josephine ^a   King, Tamara ^a   Porreca, Frank ^a  

^a UNIVERSITY OF ARIZONA   (United States)

Author keywords

descending facilitation; hyperalgesia; morphine dependence; Naloxone induced withdrawal; RVM

Indexed keywords

1 [2,3 DIHYDRO 1 (2' METHYLPHENACYL) 2 OXO 5 PHENYL 1H 1,4 BENZODIAZEPIN 3 YL] 3 (3 METHYLPHENYL)UREA; KYNURENIC ACID; LIDOCAINE; MORPHINE; NALOXONE; ONDANSETRON;

ANIMAL EXPERIMENT; ARTICLE; BRAIN NERVE CELL; CONTROLLED STUDY; DIARRHEA; DRUG EFFECT; FACILITATION; HOT PLATE TEST; HYPERALGESIA; HYPERSENSITIVITY; MALE; MEDULLA OBLONGATA; MORPHINE ADDICTION; NEUROTRANSMISSION; NONHUMAN; RAT; ROSTRAL VENTROMEDIAL MEDULLA; WEIGHT REDUCTION; WITHDRAWAL SYNDROME;

ANIMALS; DISEASE MODELS, ANIMAL; EFFERENT PATHWAYS; HYPERALGESIA; MALE; MEDULLA OBLONGATA; MORPHINE DEPENDENCE; NALOXONE; RATS; RATS, SPRAGUE-DAWLEY; SUBSTANCE WITHDRAWAL SYNDROME;

EID: 79958108723     PISSN: 15265900     EISSN: 15288447     Source Type: Journal    
DOI: 10.1016/j.jpain.2010.12.007     Document Type: Article

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