Development of a successive targeting liposome with multi-ligand for efficient targeting gene delivery

Journal of Gene Medicine

Volumn 13, Issue 5, 2011, Pages 290-301

  Ma, Kun ^a,b   Shen, Haijun ^a   Shen, Song ^a   Xie, Men ^a   Mao, Chuanbin ^b   Qiu, Liyan ^a   Jin, Yi ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b UNIVERSITY OF OKLAHOMA   (United States)

Author keywords

Gene delivery; Liposome; Nonviral vector; Polyethylenimine; Target delivery

Indexed keywords

[(2 LACTOYLAMIDO) ETHYLAMINO]FORMIC ACID CHOLESTEROL ESTER; CHOLESTEROL; CHOLESTEROL ESTER; GALACTOSE; LACTOBIONIC ACID; LIPOSOME; POLYETHYLENEIMINE; TRIAMCINOLONE ACETONIDE; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN HEPG2; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; ENDOCYTOSIS; GENE EXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; IN VITRO GENE TRANSFER; IN VIVO GENE TRANSFER; IN VIVO STUDY; LIPID BILAYER; LIPOSOMAL GENE DELIVERY SYSTEM; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; TRANSGENICS;

ANIMALS; DNA; GENE EXPRESSION REGULATION; GENE TRANSFER TECHNIQUES; HEK293 CELLS; HEP G2 CELLS; HUMANS; LIGANDS; LIPOSOMES; LIVER; MICE; POLYETHYLENEIMINE; TRANSDUCTION, GENETIC; TRANSFECTION; TRANSGENES;

MUS;

EID: 79958101271     PISSN: 1099498X     EISSN: 15212254     Source Type: Journal    
DOI: 10.1002/jgm.1569     Document Type: Article

References (32)

1. van der Aa MA, Mastrobattista E, Oosting RS, Hennink WE, Koning GA, Crommelin DJ. The nuclear pore complex: the gateway to successful nonviral gene delivery. Pharm Res 2006; 23: 447-459.
2. Nishikawa M, Huang L. Non-viral vectors in the new millennium: delivery barriers in gene transfer. Hum Gene Ther 2001; 12: 861-870.
3. Akita H, Kudo A, Minoura A, Yamaguti M, et al. Multi-layered nanoparticles for penetrating the endosome and nuclear membrane via a step-wise membrane fusion process. Biomaterials 2009; 30: 2940-2949.
4. Brunner S, Sauer T, Carotta S, Cotten M, Saltik M, Wagner E. Cell cycle dependence of gene transfer by lipoplex, polyplex and recombinant adenovirus. Gene Ther 2000; 7: 401-407.
5. Pouton CW, Wagstaff KM, Roth DM, Moseley GW, Jans DA. Targeted delivery to the nucleus. Adv Drug Deliv Rev 2007; 59: 698-717.
6. Futaki S, Nakase I, Suzuki T, Zhang Yj, Sugiur Y. Translocation of branched-chain arginine peptides through cell membranes: flexibility in the spatial disposition of positive charges in membrane-permeable peptides. Biochemistry 2002; 41: 7925-7930.
7. Arima H, Chihara Y, Arizono M, et al. Enhancement of gene transfer activity mediated by mannosylated dendrimer/α-cyclodextrin conjugate (generation 3, G3). J Control Release 2006; 116: 64-74.
8. Rebuffat A, Bernasconi A, Ceppi M, et al. Selective enhancement of gene transfer by steroid-mediated gene delivery. Nat Biotechnol 2001; 19: 1155-1161.
9. Braun S, Jenny C, Thioudellet C, et al. In vitro and in vivo effects of glucocorticoids on gene transfer to skeletal muscle. FEBS Lett 1999; 454: 277-282.
10. Rebuffat AG, Nawrocki AR, Nielsen PE, et al. Gene delivery by a steroid-peptide nucleic acid conjugate. FASEB J 2002; 16: 1426-1428.
11. Gruneich JA, Price A, Zhu J, Diamond SL. Cationic corticosteroid for nonviral gene delivery. Gene Ther 2004; 11: 668-674.
12. Choi JS, Ko KS, Park JS, Kim YH, Kim SW, Lee M. Dexamethasone conjugated poly (amidoamine) dendrimer as a gene carrier for efficient nuclear translocation. Int J Pharm 2006; 320: 171-178.
13. Mi Bae Y, Choi H, Lee S, et al. Dexamethasone-conjugated low molecular weight polyethylenimine as a nucleus-targeting lipopolymer gene carrier. Bioconjug Chem 2007; 18: 2029-2036.
14. Ma K, Hu M, Qi Y, et al. PAMAM-triamcinolone acetonide conjugate as a nucleus-targeting gene carrier for enhanced transfer activity. Biomaterials 2009; 30: 6109-6118.
15. Ma K, Hu M, Qi Y, et al. Structure-transfection activity relationships with glucocorticoid-polyethylenimine conjugate nuclear gene delivery systems. Biomaterials 2009; 30: 3780-3789.
16. Kim TH, Park IK, Nah JW, Choi YJ, Cho CS. Galactosylated chitosan/DNA nanoparticles prepared using water-soluble chitosan as a gene carrier. Biomaterials 2004; 25: 3783-3792.
17. Fumoto S, Kawakami S, Ito Y, Shigeta K, Yamashita F, Hashida M. Enhanced hepatocyte-selective in vivo gene expression by stabilized galactosylated liposome/plasmid DNA complex using sodium chloride for complex formation. Mol Ther 2004; 10: 719-729.
18. Kim TH, Kim SI, Akaike T, Cho CS. Synergistic effect of poly(ethylenimine) on the transfection efficiency of galactosylated chitosan/DNA complexes. J Control Release 2005; 105: 354-366.
19. Zhang XQ, Wang XL, Zhang PC, et al. Galactosylated ternary DNA/polyphosphoramidate nanoparticles mediate high gene transfection efficiency in hepatocytes. J Control Release 2005; 102: 749-763.
20. Shigeta K, Kawakami S, Higuchi Y, et al. Novel histidine-conjugated galactosylated cationic liposomes for efficient hepatocyte-selective gene transfer in human hepatoma HepG2 cells. J Control Release 2007; 118: 262-270.
21. Park IK, Kim TH, Park YH, et al. Galactosylated chitosan-graft-poly(ethylene glycol) as hepatocyte-targeting DNA carrier. J Control Release 2001; 76: 349-362.
22. Köster F, Schröder A, Finas D, Hauser C, Diedrich K, Felberbaum R. Cell-specific enhancement of liposomal transfection by steroids in steroid receptor expressing cells. Int J Mol Med 2006; 18: 1201-1205.
23. Ma K, Hu M-X, Xie M, et al. Investigation of Polyethylenimine-grafted-triamcinolone acetonide as nucleus-targeting gene delivery systems. J Gene Med 2010; 12: 669-680.
24. Kim TH, Park IK, Nah JW, Choi YJ, Cho CS. Galactosylated chitosan/DNA nanoparticles prepared using water-soluble chitosan as a gene carrier. Biomaterials 2004; 25: 3783-3792.
25. Yamazaki Y, Nango M, Matsuura M, Hasegawa Y, Hasegawa M, Oku N. Polycation liposomes, a novel nonviral gene transfer system, constructed from cetylated polyethylenimine. Gene Ther 2000; 7: 1148-1155.
26. Morimoto K, Nishikawa M, Kawakami S, et al. Molecular weight-dependent gene transfection activity of unmodified and galactosylated polyethyleneimine on hepatoma cells and mouse liver. Mol Ther 2003; 7: 254-261.
27. Dunkerton LV, Markland FS, Li MP. Affinity-Labelling Corticoids I. Synthesis of 21-chloroprogesterone, deoxycorticosterone 2l-(l-imidazole) carboxylate, 21-deoxy-21-chloro dexamethasone, and dexamethasone 21-mesylate, 21-bromoacetate, and 21-iodoacetate. Steroids 1982; 39: 2828.
28. Simmons SS, Pons M, Johnson DF. α-Keto mesylate: a reactive, thiol-specific functional group. J Org Chem 1980; 45: 3084-3088.
29. Dahlberg E, Thalén A, Brattsand R, et al. Correlation between chemical structure, receptor binding, and biological activity of some novel, highly active, 16α, 17α-acetal-substituted glucocorticoids. Mol Pharmacol 1983; 25: 70-78.
30. Yu FB, Jiang TY, Zhang JH, Cheng LH, Wang SL. Galactosylated liposomes as oligodexynucleotides carrier for hepatocyte-selective targeting. Pharmazie 2007; 62: 528-533.
31. Willams TJ, Plessas NR, Goldstein IJ. Synthsis of a new class of model glycolipids. Carbohydrate Res 1978; 67: C1-C3.
32. De Smedt SC, Remaut K, Lucas B, Braeckmans K, Sanders NN, Demeester J. Studying biophysical barriers to DNA delivery by advanced light microscopy. Adv Drug Deliv Rev 2005; 57: 191-210.