Galactosylated liposomes as oligodeoxynucleotides carrier for hepatocyte-selective targeting

Pharmazie

Volumn 62, Issue 7, 2007, Pages 528-533

  Yu, Fengbo ^a   Jiang, Tongying ^a   Zhang, Jinghai ^a   Cheng, Lihua ^a   Wang, Siling ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

(5 CHOLESTAN 3BETA YL) 1 [2 (LACTOBIONYLAMIDO)ETHYLAMIDO]FORMATE; 1,1' DIOCTADECYL 3,3,3',3' TETRAMETHYLIODOCARBOCYANINE PERCHLORATE; 2 (CHOLESTERYLOXYCARBONYLAMINO)ETHYLAMINE; AMINE; CARBOCYANINE; CARBONYL DERIVATIVE; CHOLESTEROL; GALACTOSE; GLYCOLIPID; LACTOBIONO 1,5 LACTONE; LACTONE DERIVATIVE; LIPOSOME; OLIGODEOXYNUCLEOTIDE DERIVATIVE; PERCHLORATE; SURVIVIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL STRAIN HEPG2; CHEMICAL REACTION; CONTROLLED STUDY; FILM; GENE EXPRESSION; HUMAN; HUMAN CELL; HYDRATION; LIVER CELL; REACTION ANALYSIS; SYNTHESIS; TARGET CELL;

ANIMALS; APOPTOSIS; CELL CYCLE; DRUG CARRIERS; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; EXCIPIENTS; GALACTOSE; HEPATOCYTES; HUMANS; LIPOSOMES; LIVER; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MICROTUBULE-ASSOCIATED PROTEINS; NEOPLASM PROTEINS; OLIGONUCLEOTIDES; SPECTROPHOTOMETRY, INFRARED; SPLEEN;

EID: 34447530894     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: 10.1691/ph.2007.7.6232     Document Type: Article

References (28)

1. Carter BZ, Milella M, Altieri DC, Andreeff M (2001) Cytokine-regulated expression of survivin in myeloid leukemia. Blood 97: 2784-2790.
2. Carter BZ, Wang RY, Schober WD, Milella M, Chism D, Andreeff M (2003) Targeting survivin expression induces cell proliferation defect and subsequent cell death involving mitochondrial pathway in myeloid leukemic cells. Cell Cycle 2: 488-493.
3. Degols G, Leonetti JP, Gagnor C, Lemaitre M, Lebleu B (1998) Antiviral activity and possible mechanisms of action of oligonucleotides-poly(L-lysine) conjugates targeted to vesicular stomatitis virus mRNA and genomic RNA. Nucleic Acids Res 17: 9341-9350.
4. Fillion P, Desjardins A, Sayasith K, Lagace J (2001) Encapsulation of DNA in negatively charged liposomes and inhibition of bacterial gene expression with fluid liposome-encapsulated antisense oligonucleotides. Biochim Biophys Acta 1515: 44-54.
5. Gaus H, Olsen P, Sooy KV, Rentel C, Turney B, Walker KL, McArdle JV, Capaldi DC (2005) Trichloroacetaldehyde modified oligonucleotides. Bioorg Med Chem Lett 15: 4118-4124.
6. Gupta PK, Huang CT (1989) Quantitative evaluation of targeted drug delivery systems. Int J Pharm 56: 217-226.
7. Juliano RL, Yoo H (2000) Aspects of the transport and delivery of antisense oligonucleotides. Curr Opin Mol Ther 2: 297-303.
8. Kang HC, Kim S, Lee M, Bae YH (2005) Polymeric gene carrier for insulin secreting cells: poly(L-lysine)-g-sulfonylurea for receptor mediated transfection. J Control Release 105: 164-176.
9. Kawakami S, Munakata C, Fumoto S, Yamashita F, Hashida M (2001) Novel galactosylated liposomes for hepatocyte-selective targeting of lipophilic drugs. J Pharm Sci 90: 105-113.
10. Kawakami S, Yamashita F, Nishikawa M, Takakura Y, Hashida M (1998) Asialoglycoprotein receptor-mediated gene transfer using novel galactosylated cationic liposomes. Biochem Biophys Res Commun 252: 78-83.
11. Kim CK, Min KH, Oh YK, Park KM, Kim KM (1996) Preparation and lectin binding characteristics of N-stearyl lactobionamide liposomes, Int J Pharm 128: 65-71.
12. Letsinger RL, Zhang GR, Sun DK, Ikeuchi T, Sarin PS (1989) Cholesteryl-conjugated oligonucleotides: Synthesis, properties, and activity as inhibitors of replication of human immunodeficiency virus in cell culture. Pro Natl Acad Sci USA 86: 6553-6556.
13. Liang Y, Osborne MC, Monia BP, Bhanot S, Watts LM, She P, Decarlo SO, Chen X, Demarest K (2005) Antisense oligonucleotides targeted against glucocorticoid receptor reduce hepatic glucose production and ameliorate hyperglycemia in diabetic mice. Metabolism 54: 848-855.
14. Mahato RI, Kawabata K, Nomura T, Takakura Y, Hashida M (1995) Physicochemical and pharmacokinetic characteristics of plasmid DNA/cationic liposome complexes. J Pharm Sci 84: 1267-1271.
15. Mahato RI, Takemura S, Akamatsu K, Nishikawa M, Takakura Y, Hashida M (1997) Physicochemical and disposition characteristics of antisense oligonucleotides complexed with glycosylated poly(L-lysine). Biochem Pharmacol 53: 887-895.
16. Maitani Y, Kawano K, Yamada K, Nagai T, Takayama K (2001) Efficiency of liposomes surface-modified with soybean-derived sterylglucoside as a liver targeting carrier in HepG2 cells. J Control Release 75: 381-389.
17. Nishikawa M, Miyazaki C, Yamashita F, Takakura Y, Hashida M (1995) Galactosylated proteins are recognized by the liver according to the surface density of galactose moieties. Am J Physiol 268: G849-856.
18. Noguchi S, Hirashima N, Nakanishi M (2003) Asialoganglioside Enhances the efficiency of gene transfection mediated by cationic liposomes with a cationic cholesterol derivative. Biol Pharm Bull 26: 1306-1310.
19. Robert A, Olie ZI, Uwe ZI (2001) Targeting tumor cell resistance to apoptosis induction with antisense oligonucleotides: progress and therapeutic potential. Drug Resistance Updates 4: 9-15.
20. Rolland AP (1998) From genes to gene medicines: recent advances in nonviral gene delivery. Crit Rev Ther Drug Carrier Syst 15: 143-198.
21. Sapra P, Allen TM (1998) Recent advances in liposome technologies and their applications for systemic gene delivery. Adv Drug Del Rev 30: 73-83.
22. Sasaki M, Hayashi J, Fujii M, Koizumi K, Fujita H, Kobayashi M, Kawakubo Y, Ito A (2001) Neutral liposome-mediated delivery process of fluorescein-modified oligonucleotides in cultured human keratinocytes. J Photochem Photobiol B 60: 120-128.
23. Singh M, Ariatti M (2003) Targeted gene delivery into HepG2 cells using complexes containing DNA, canonized asialoorosomucoid and activated cationic liposomes. J Control Release 92: 383-394.
24. Sun X, Wu Y, Hu HY, Zhang ZR (2005) Targeted gene delivery to hepatoma cells using galactosylated liposome-polycation-DNA complexes (LPD). J Drug Target 13: 121-128.
25. Wang SL, Cheng LH, Yu FB, Pan WS, Zhang JH (2006a) Delivery of different length poly(l-lysine)-conjugated ODN to HepG2 cells using N- stearyllactobionamide-modified liposomes and their enhanced cellular biological effects. Inter J Pharm 311: 82-88.
26. Wang SN, Deng YH, Xu H, Wu HB, Qiu YK, Chen DW (2006b) Synthesis of a novel galactosylated lipid and its application to the hepatocyte-selective targeting of liposomal doxorubicin. Eur J Pharm Biopharm 62: 32-38.
27. Weyermann J, Lochmann D, Zimmer A (2004) Comparison of antisense oligonucleotide drug delivery systems. J Control Release 100: 411-423.
28. Wu GY, Wu CH (1987) Receptor-mediated in vitro gene transformation by a soluble DNA carrier system. J Biol Chem 262: 4429-4432.