-
1
-
-
0032085075
-
Epidemiology of low back pain
-
Anderson GB. Epidemiology of low back pain. Acta Orthop Scand 1998;281:28-31.
-
(1998)
Acta Orthop Scand
, vol.281
, pp. 28-31
-
-
Anderson, G.B.1
-
2
-
-
0342514575
-
Low back pain in relation to lumbar degeneration
-
Luoma K, Riihimaki H, Luukkonen R et al. Low back pain in relation to lumbar degeneration. Spine 2000;25:487-492.
-
(2000)
Spine
, vol.25
, pp. 487-492
-
-
Luoma, K.1
Riihimaki, H.2
Luukkonen, R.3
-
3
-
-
0036400315
-
The economic burden of low back pain: a review of studies published between 1996 and 2001
-
Maetzel A, Li L. The economic burden of low back pain: a review of studies published between 1996 and 2001. Best Pract Res Clin Rheumatol 2002;16:23-30.
-
(2002)
Best Pract Res Clin Rheumatol
, vol.16
, pp. 23-30
-
-
Maetzel, A.1
Li, L.2
-
4
-
-
2942536282
-
Intervertebral disc cell therapy for regeneration: mesenchymal stem cell implantation in rat intervertebral discs
-
Crevensten G, Walsh AJ, Ananthakrishnan D et al. Intervertebral disc cell therapy for regeneration: mesenchymal stem cell implantation in rat intervertebral discs. Ann Biomed Eng 2004;32:430-434.
-
(2004)
Ann Biomed Eng
, vol.32
, pp. 430-434
-
-
Crevensten, G.1
Walsh, A.J.2
Ananthakrishnan, D.3
-
5
-
-
0346847531
-
Biologic strategies for the therapy of intervertebral disc degeneration
-
Gruber HE, Hanley EN Jr. Biologic strategies for the therapy of intervertebral disc degeneration. Expert Opin Biol Ther 2003;3:1209-1214.
-
(2003)
Expert Opin Biol Ther
, vol.3
, pp. 1209-1214
-
-
Gruber, H.E.1
Hanley Jr, E.N.2
-
7
-
-
33747355707
-
What is intervertebral disc degeneration, and what causes it
-
Adams MA, Roughley PJ. What is intervertebral disc degeneration, and what causes it? Spine 2006;31: 2151- 2161.
-
(2006)
Spine
, vol.31
, pp. 2151-2161
-
-
Adams, M.A.1
Roughley, P.J.2
-
8
-
-
0035343467
-
Biochemistry of intervertebral disc degeneration and the potential for gene therapy applications
-
Cassinelli EH, Hall RA, Kang JD. Biochemistry of intervertebral disc degeneration and the potential for gene therapy applications. Spine J 2001;1:205-214.
-
(2001)
Spine J
, vol.1
, pp. 205-214
-
-
Cassinelli, E.H.1
Hall, R.A.2
Kang, J.D.3
-
9
-
-
0036204872
-
Current understanding of cellular and molecular events in intervertebral disc degeneration: implications for therapy
-
Freemont AJ, Watkins A, Le Maitre C, Jeziorska M, Hoyland JA. Current understanding of cellular and molecular events in intervertebral disc degeneration: implications for therapy. J Pathol 2002;196:374-379.
-
(2002)
J Pathol
, vol.196
, pp. 374-379
-
-
Freemont, A.J.1
Watkins, A.2
Le Maitre, C.3
Jeziorska, M.4
Hoyland, J.A.5
-
10
-
-
33645558156
-
Lumbar disc degeneration: epidemiology and genetics
-
Battié MC, Videman T. Lumbar disc degeneration: epidemiology and genetics. J Bone Joint Surg Am 2006;88:3-9.
-
(2006)
J Bone Joint Surg Am
, vol.88
, pp. 3-9
-
-
Battié, M.C.1
Videman, T.2
-
11
-
-
84876428320
-
Genetic influence on intervertebral disc degeneration
-
Froes N, Nunes F, Negrelli W. Genetic influence on intervertebral disc degeneration. Acta Ortop Bras 2005;13:255-257.
-
(2005)
Acta Ortop Bras
, vol.13
, pp. 255-257
-
-
Froes, N.1
Nunes, F.2
Negrelli, W.3
-
12
-
-
0033575339
-
An allele of COL9A2 associated with intervertebral disc disease
-
Annunen S, Paassilta P, Lohiniva J et al. An allele of COL9A2 associated with intervertebral disc disease. Science 1999;285:409-412.
-
(1999)
Science
, vol.285
, pp. 409-412
-
-
Annunen, S.1
Paassilta, P.2
Lohiniva, J.3
-
13
-
-
29444444139
-
The TRP2 allele of COL9A2 is an age-dependent risk factor for the development and severity of intervertebral disc degeneration
-
Jim JJ, Noponen-Hietala N, Cheung KM et al. The TRP2 allele of COL9A2 is an age-dependent risk factor for the development and severity of intervertebral disc degeneration. Spine 2005;30:2735-2742.
-
(2005)
Spine
, vol.30
, pp. 2735-2742
-
-
Jim, J.J.1
Noponen-Hietala, N.2
Cheung, K.M.3
-
14
-
-
0037439062
-
Recent advances in disc cell biology
-
Gruber HE, Hanley EN Jr. Recent advances in disc cell biology. Spine 2003;28:186-193.
-
(2003)
Spine
, vol.28
, pp. 186-193
-
-
Gruber, H.E.1
Hanley Jr, E.N.2
-
15
-
-
6344254760
-
Gene therapy in clinical medicine
-
Selkirk SM. Gene therapy in clinical medicine. Postgrad Med J 2004;80:560-570.
-
(2004)
Postgrad Med J
, vol.80
, pp. 560-570
-
-
Selkirk, S.M.1
-
16
-
-
0036204872
-
Current understanding of cellular and molecular events in intervertebral disc degeneration: implications of therapy
-
Freemont AJ, Watkins A, Le Maitre C et al. Current understanding of cellular and molecular events in intervertebral disc degeneration: implications of therapy. J Pathol 2002;196:374-379.
-
(2002)
J Pathol
, vol.196
, pp. 374-379
-
-
Freemont, A.J.1
Watkins, A.2
Le Maitre, C.3
-
17
-
-
0031005786
-
Transfer of genes to chondrocytic cells of the lumbar spine Proposal for a treatment strategy of spinal disorders by local gene therapy
-
Wehling P, Schulitz KP, Robbins PD, Evans CH, Reinecke JA. Transfer of genes to chondrocytic cells of the lumbar spine. Proposal for a treatment strategy of spinal disorders by local gene therapy. Spine 1997;22:1092-1097.
-
(1997)
Spine
, vol.22
, pp. 1092-1097
-
-
Wehling, P.1
Schulitz, K.P.2
Robbins, P.D.3
Evans, C.H.4
Reinecke, J.A.5
-
18
-
-
0032533617
-
Adenovirus-mediated gene transfer to nucleus pulposus cells Implications for the treatment of intervertebral disc degeneration
-
Nishida K, Kang JD, Suh JK, Robbins PD, Evans CH, Gilbertson LG. Adenovirus-mediated gene transfer to nucleus pulposus cells. Implications for the treatment of intervertebral disc degeneration. Spine 1998;15;23:2437-2442.
-
(1998)
Spine
, vol.15
, Issue.23
, pp. 2437-2442
-
-
Nishida, K.1
Kang, J.D.2
Suh, J.K.3
Robbins, P.D.4
Evans, C.H.5
Gilbertson, L.G.6
-
19
-
-
33645772699
-
Efficient and stable gene expression in rabbit intervertebral disc cells transduced with a recombinant baculovirus vector
-
Liu X, Li K, Song J, Liang C, Wang X, Chen X. Efficient and stable gene expression in rabbit intervertebral disc cells transduced with a recombinant baculovirus vector. Spine 2006;31:732-735.
-
(2006)
Spine
, vol.31
, pp. 732-735
-
-
Liu, X.1
Li, K.2
Song, J.3
Liang, C.4
Wang, X.5
Chen, X.6
-
20
-
-
0033404813
-
Modulation of the biologic activity of the rabbit intervertebral disc by gene therapy: an in vivo study of adenovirus-mediated transfer of the human transforming growth factor beta 1 encoding gene
-
Nishida K, Kang JD, Gilbertson LG et al. Modulation of the biologic activity of the rabbit intervertebral disc by gene therapy: an in vivo study of adenovirus-mediated transfer of the human transforming growth factor beta 1 encoding gene. Spine 1999;24:2419-2425.
-
(1999)
Spine
, vol.24
, pp. 2419-2425
-
-
Nishida, K.1
Kang, J.D.2
Gilbertson, L.G.3
-
21
-
-
0034667326
-
Human intervertebral disc cells are genetically modifiable by adenovirus-mediated gene transfer: implications for the clinical management of intervertebral disc disorders
-
Moon SH, Gilbertson LG, Nishida K et al. Human intervertebral disc cells are genetically modifiable by adenovirus-mediated gene transfer: implications for the clinical management of intervertebral disc disorders. Spine 2000;15;25:2573-2579.
-
(2000)
Spine
, vol.15
, Issue.25
, pp. 2573-2579
-
-
Moon, S.H.1
Gilbertson, L.G.2
Nishida, K.3
-
22
-
-
33644619565
-
Safety assessment of intradiscal gene transfer: a pilot study
-
Wallach CJ, Kim JS, Sobajima S et al. Safety assessment of intradiscal gene transfer: a pilot study. Spine J 2006;6:107-112.
-
(2006)
Spine J
, vol.6
, pp. 107-112
-
-
Wallach, C.J.1
Kim, J.S.2
Sobajima, S.3
-
23
-
-
33644951210
-
A preliminary in vitro study into the use of IL-1Ra gene therapy for the inhibition of intervertebral disc degeneration
-
Le Maitre CL, Freemont AJ, Hoyland JA. A preliminary in vitro study into the use of IL-1Ra gene therapy for the inhibition of intervertebral disc degeneration. IntJ Exp Pathol 2006;87:17-28.
-
(2006)
IntJ Exp Pathol
, vol.87
, pp. 17-28
-
-
Le Maitre, C.L.1
Freemont, A.J.2
Hoyland, J.A.3
-
24
-
-
34848893110
-
Interleukin-1 receptor antagonist delivered directly and by gene therapy inhibits matrix degradation in the intact degenerate human intervertebral disc: an in situ zymographic and gene therapy study
-
Le Maitre CL, Hoyland JA, Freemont AJ. Interleukin-1 receptor antagonist delivered directly and by gene therapy inhibits matrix degradation in the intact degenerate human intervertebral disc: an in situ zymographic and gene therapy study. Arthritis Res Ther 2007;9:R83.
-
(2007)
Arthritis Res Ther
, vol.9
-
-
Le Maitre, C.L.1
Hoyland, J.A.2
Freemont, A.J.3
-
25
-
-
12444273295
-
Potential use of Sox9 gene therapy for intervertebral degenerative disc disease
-
Paul R, Haydon RC, Cheng H et al. Potential use of Sox9 gene therapy for intervertebral degenerative disc disease. Spine 2003;28:755-763.
-
(2003)
Spine
, vol.28
, pp. 755-763
-
-
Paul, R.1
Haydon, R.C.2
Cheng, H.3
-
26
-
-
43749083304
-
Mouse growth and differentiation factor-5 protein and ADN therapy potentiates intervertebral disc cell aggregation and chondrogenic gene expression
-
Cui M, Wan Y, Anderson DG et al. Mouse growth and differentiation factor-5 protein and ADN therapy potentiates intervertebral disc cell aggregation and chondrogenic gene expression. Spine J 2008;8:287--295.
-
(2008)
Spine J
, vol.8
, pp. 287-295
-
-
Cui, M.1
Wan, Y.2
Anderson, D.G.3
-
27
-
-
33644619565
-
Safety assessment of intradiscal gene transfer: a pilot study
-
Wallach CJ, Kim JS, Sobajima S et al. Safety assessment of intradiscal gene transfer: a pilot study. Spine J 2006;6:107-112.
-
(2006)
Spine J
, vol.6
, pp. 107-112
-
-
Wallach, C.J.1
Kim, J.S.2
Sobajima, S.3
-
28
-
-
34249908639
-
Regulation of transgene expression using an inducible system for improved safety of intervertebral disc gene therapy
-
Vadalà G, Sowa GA, Smith L et al. Regulation of transgene expression using an inducible system for improved safety of intervertebral disc gene therapy. Spine 2007;32:1381-1387.
-
(2007)
Spine
, vol.32
, pp. 1381-1387
-
-
Vadalà, G.1
Sowa, G.A.2
Smith, L.3
-
29
-
-
33745111263
-
Sustained transgene expression in intervertebral disc cells in vivo mediated by microbubble-enhanced ultrasound gene therapy
-
Nishida K, Doita M, Takada T et al. Sustained transgene expression in intervertebral disc cells in vivo mediated by microbubble-enhanced ultrasound gene therapy. Spine 2006;31:1415-1419.
-
(2006)
Spine
, vol.31
, pp. 1415-1419
-
-
Nishida, K.1
Doita, M.2
Takada, T.3
-
30
-
-
34248326042
-
Nucleus pulposus cellular longevity by telomerase gene therapy
-
Chung SA, Wei AQ, Connor DE et al. Nucleus pulposus cellular longevity by telomerase gene therapy. Spine 2007;32:1188-1196.
-
(2007)
Spine
, vol.32
, pp. 1188-1196
-
-
Chung, S.A.1
Wei, A.Q.2
Connor, D.E.3
-
31
-
-
0036668306
-
Autologous intervertebral disc cell implantation: a model using Psammomys obesus, the sand rat
-
Gruber HE, Johnson TL, Leslie K et al. Autologous intervertebral disc cell implantation: a model using Psammomys obesus, the sand rat. Spine 2002;27: 1626-1633
-
(2002)
Spine
, vol.27
, pp. 1626-1633
-
-
Gruber, H.E.1
Johnson, T.L.2
Leslie, K.3
-
32
-
-
3242681459
-
Upregulation of the viability of nucleus pulposus cells by boné marrow-derived stromal cells: significance of direct cellto-cell contact in coculture system
-
Yamamoto Y, Mochida J, Sakai D et al. Upregulation of the viability of nucleus pulposus cells by boné marrow-derived stromal cells: significance of direct cellto-cell contact in coculture system. Spine 2004:1508--1514.
-
(2004)
Spine
, pp. 1508-1514
-
-
Yamamoto, Y.1
Mochida, J.2
Sakai, D.3
-
33
-
-
0346486744
-
Biochemical injection treatment for discogenic low back pain: a pilot study
-
Klein RG, Eek BC, O'Neill CW et al. Biochemical injection treatment for discogenic low back pain: a pilot study. Spine J 2003;3:220-226.
-
(2003)
Spine J
, vol.3
, pp. 220-226
-
-
Klein, R.G.1
Eek, B.C.2
O'Neill, C.W.3
-
34
-
-
0036894339
-
New in vivo animal model to create intervertebral disc degeneration and to investigate the effects of therapeutic strategies to stimulate disc regeneration
-
Kroeber MW, Unglaub F, Wang H et al. New in vivo animal model to create intervertebral disc degeneration and to investigate the effects of therapeutic strategies to stimulate disc regeneration. Spine 2002;27:2684-2690.
-
(2002)
Spine
, vol.27
, pp. 2684-2690
-
-
Kroeber, M.W.1
Unglaub, F.2
Wang, H.3
-
35
-
-
14044269226
-
Differentiation of mesenchymal stem cells towards a nucleus pulposus-like phenotype in vitro: implications for cell-based transplantation therapy
-
Risbud MV, Albert TJ, Guttapalli A et al. Differentiation of mesenchymal stem cells towards a nucleus pulposus-like phenotype in vitro: implications for cell-based transplantation therapy. Spine 2004;29: 2627-2632.
-
(2004)
Spine
, vol.29
, pp. 2627-2632
-
-
Risbud, M.V.1
Albert, T.J.2
Guttapalli, A.3
-
36
-
-
4644349216
-
Stem cell regeneration of the nucleus pulposus
-
Risbud MV, Shapiro IM, Vaccaro AR et al. Stem cell regeneration of the nucleus pulposus. Spine J 2004;4:348-353
-
(2004)
Spine J
, vol.4
, pp. 348-353
-
-
Risbud, M.V.1
Shapiro, I.M.2
Vaccaro, A.R.3
-
37
-
-
15544381999
-
Induction of intervertebral disc-like cells from adult mesenchymal tem cells
-
Steck E, Bertram H, Abel R et al. Induction of intervertebral disc-like cells from adult mesenchymal tem cells. Stem Cells 2005;23:403-411.
-
(2005)
Stem Cells
, vol.23
, pp. 403-411
-
-
Steck, E.1
Bertram, H.2
Abel, R.3
-
38
-
-
11844266479
-
Bone mesenchymal stem cells transplanted into rabbit intervertebral discs can increase proteoglycans
-
Zhang YG, Guo X, Xu P et al. Bone mesenchymal stem cells transplanted into rabbit intervertebral discs can increase proteoglycans. Clin Orthop Relat Res 2005;430:219-226.
-
(2005)
Clin Orthop Relat Res
, vol.430
, pp. 219-226
-
-
Zhang, Y.G.1
Guo, X.2
Xu, P.3
-
39
-
-
0037708391
-
Transplantation of mesenchymal stem cells embedded in Atelocollagen gel to the intervertebral disc: a potencial therapeutic model for disc degeneration
-
Sakai D, Mochida J, Yamamoto Y et al. Transplantation of mesenchymal stem cells embedded in Atelocollagen gel to the intervertebral disc: a potencial therapeutic model for disc degeneration. Biomaterials 2003,24:3531-3541.
-
(2003)
Biomaterials
, vol.24
, pp. 3531-3541
-
-
Sakai, D.1
Mochida, J.2
Yamamoto, Y.3
-
40
-
-
0036184589
-
Human autologous culture expanded boné marrow mesenchymal cell transplantation for repair of cartilage defects in osteoarthritic knees
-
Wakitani S, Imoto K, Yamamoto T et al. Human autologous culture expanded boné marrow mesenchymal cell transplantation for repair of cartilage defects in osteoarthritic knees. Osteoarthritic Cartilage 2002;10:199-206.
-
(2002)
Osteoarthritic Cartilage
, vol.10
, pp. 199-206
-
-
Wakitani, S.1
Imoto, K.2
Yamamoto, T.3
-
41
-
-
1642579717
-
In vivo growth factor treatment of degenerated intervertebral discs
-
Walsh AJ, Bradford DS, Lotz JC. In vivo growth factor treatment of degenerated intervertebral discs. Spine 2004;29:156-163.
-
(2004)
Spine
, vol.29
, pp. 156-163
-
-
Walsh, A.J.1
Bradford, D.S.2
Lotz, J.C.3
|