Antibiotic-releasing porous polymethylmethacrylate/gelatin/antibiotic constructs for craniofacial tissue engineering

Journal of Controlled Release

Volumn 152, Issue 1, 2011, Pages 196-205

  Shi, Meng ^a   Kretlow, James D ^a   Spicer, Patrick P ^a   Tabata, Yasuhiko ^b   Demian, Nagi ^c   Wong, Mark E ^c   Kasper, F Kurtis ^a   Mikos, Antonios G ^a  

^a Rice University   (United States)

^b KYOTO UNIVERSITY   (Japan)

^c UNIVERSITY OF TEXAS   (United States)

Author keywords

Antibiotic delivery; Bone tissue engineering; Colistin; Gelatin microparticles; Polymethylmethacrylate; Scaffolds

Indexed keywords

BONE TISSUE ENGINEERING; COLISTIN; CRANIOFACIAL; DRUG CONTENT; DRUG RELEASE KINETICS; DRUG SOLUTIONS; FABRICATION PARAMETERS; FUNCTIONAL SPACES; GELATIN MICROPARTICLES; IN-VITRO; LOCAL INFECTION; MATERIAL COMPOSITIONS; METHYL METHACRYLATES; REGENERATIVE MEDICINE; RELEASE KINETICS; RELEASE RATE; SEQUENTIAL ASSEMBLY; TISSUE CONSTRUCTS; TISSUE DEFECTS; TISSUE HEALING; TWO STAGE; WOUND SITE;

ANTIBIOTICS; BONE; BONE CEMENT; POLYESTERS; POROSITY; TISSUE;

TISSUE ENGINEERING;

ANTIBIOTIC AGENT; BONE CEMENT; COLISTIN; GELATIN; NANOPARTICLE; POLY(METHYL METHACRYLATE);

ANIMAL TISSUE; ARTICLE; BONE TISSUE; COMPOSITE MATERIAL; CRANIOFACIAL MORPHOLOGY; CROSS LINKING; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG SOLUTION; IN VITRO STUDY; KINETICS; MANDIBLE; NONHUMAN; PARTICLE SIZE; POROSITY; PRIORITY JOURNAL; RABBIT; REGENERATIVE MEDICINE; TISSUE ENGINEERING;

ANTI-BACTERIAL AGENTS; COLISTIN; FACIAL BONES; GELATIN; POLYMETHYL METHACRYLATE; POROSITY; SKULL; SOLUBILITY; TISSUE ENGINEERING;

EID: 79958088325     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.01.029     Document Type: Article

References (50)

1. J.D. Kretlow, S. Young, L. Klouda, M. Wong, and A.G. Mikos Injectable biomaterials for regenerating complex craniofacial tissues Adv. Mater. Deerfield 21 2009 3368 3393
2. E.D. Rodriguez, M. Martin, R. Bluebond-Langner, and P.N. Manson Multiplanar distraction osteogenesis of fibula free flaps used for secondary reconstruction of traumatic maxillary defects J. Craniofac. Surg. 17 2006 883 888 (Pubitemid 44470167)
3. T. Kihtir, R.R. Ivatury, R.J. Simon, Z. Nassoura, and S. Leban Early management of civilian gunshot wounds to the face J. Trauma 35 1993 569 575 discussion 575-7
4. F. Akhlaghi, and F. Aframian-Farnad Management of maxillofacial injuries in the Iran-Iraq War J. Oral Maxillofac. Surg. 55 1997 927 930 discussion 930-1
5. J.D. Kretlow, M. Shi, S. Young, P.P. Spicer, N. Demian, J.A. Jansen, M.E. Wong, F.K. Kasper, and A.G. Mikos Evaluation of soft tissue coverage over porous polymethylmethacrylate space maintainers within nonhealing alveolar bone defects Tissue Eng. C Meth. 16 2010 1427 1438
6. N.M. Goodger, J. Wang, G.W. Smagalski, and B. Hepworth Methylmethacrylate as a space maintainer in mandibular reconstruction J. Oral Maxillofac. Surg. 63 2005 1048 1051 (Pubitemid 40897766)
7. M. Shi, J.D. Kretlow, A. Nguyen, S. Young, L. Scott Baggett, M.E. Wong, F.K. Kasper, and A.G. Mikos Antibiotic-releasing porous polymethylmethacrylate constructs for osseous space maintenance and infection control Biomaterials 31 2010 4146 4156
8. P.J. van Mullem, J.R. de Wijn, and J.M. Vaandrager Porous acrylic cement: evaluation of a novel implant material Ann. Plast. Surg. 21 1988 576 582 (Pubitemid 19011341)
9. JR De Wijn Poly(methyl methacrylate)-aqueous phase blends: in situ curing porous materials J. Biomed. Mater. Res. 10 1976 625 635
10. S.A. Hacking, J.D. Bobyn, K. Toh, M. Tanzer, and J.J. Krygier Fibrous tissue ingrowth and attachment to porous tantalum J. Biomed. Mater. Res. 52 2000 631 638
11. J.M. Vaandrager, P.J. van Mullem, and J.R. de Wijn Porous acrylic cement for the correction of craniofacial deformities and repair of defects, animal experimentation and two years of clinical application Biomaterials 4 1983 128 130 (Pubitemid 13105631)
12. J.D. Bobyn, G.J. Wilson, D.C. MacGregor, R.M. Pilliar, and G.C. Weatherly Effect of pore size on the peel strength of attachment of fibrous tissue to porous-surfaced implants J. Biomed. Mater. Res. 16 1982 571 584 (Pubitemid 12009635)
13. J. Siepmann, and F. Siepmann Mathematical modeling of drug delivery Int. J. Pharm. 364 2008 328 343
14. D.R. Hospenthal, and H.K. Crouch Infection control challenges in deployed US military treatment facilities J. Trauma 66 2009 S120 S128
15. P.J. Sebeny, M.S. Riddle, and K. Petersen Acinetobacter baumannii skin and soft-tissue infection associated with war trauma Clin. Infect. Dis. 47 2008 444 449
16. H.C. Yun, J.G. Branstetter, and C.K. Murray Osteomyelitis in military personnel wounded in Iraq and Afghanistan J. Trauma 64 2008 S163 S168 discussion S168
17. D. Olsen, C. Yang, M. Bodo, R. Chang, S. Leigh, J. Baez, D. Carmichael, M. Perälä, E.R. Hämäläinen, M. Jarvinen, and J. Polarek Recombinant collagen and gelatin for drug delivery Adv. Drug Deliv. Rev. 55 2003 1547 1567 (Pubitemid 37412593)
18. S. Young, M. Wong, Y. Tabata, and A.G. Mikos Gelatin as a delivery vehicle for the controlled release of bioactive molecules J. Control. Release 109 2005 256 274 (Pubitemid 41737269)
19. Y. Ikada, and Y. Tabata Protein release from gelatin matrices Adv. Drug Deliv. Rev. 31 1998 287 301 (Pubitemid 28191870)
20. M. Sutter, J. Siepmann, W.E. Hennink, and W. Jiskoot Recombinant gelatin hydrogels for the sustained release of proteins J. Control. Release 119 2007 301 312 (Pubitemid 46783840)
21. U.S. Food and Drug Administration, Center for Devices and Radiologic Health Cranioplastic K071791 approval letter, July 30, 2007 Retrieved January 12, 2011, from http://www.accessdata.fda.gov/cdrh-docs/pdf7/K071791.pdf
22. U.S. Food and Drug Administration, Center for Devices and Radiologic Health SmartSet HV Bone Cement K023012 approval letter, February 13, 2003 Retrieved January 12, 2011, from http://www.accessdata.fda.gov/cdrh-docs/pdf2/ K023012.pdf
23. U.S. Food and Drug Administration, Center for Devices and Radiologic Health Gel-Sponge ENT, Absorbable Gelatin Sponge, USP approval letter, December 9, 2008 Retrieved January 12, 2011, from http://www.accessdata.fda.gov/cdrh- docs/pdf8/K080022.pdf
24. U.S. Food and Drug Administration, Center for Devices and Radiologic Health SURGIFOAM Absorbable Gelatin Sponge, USP approval letter, September 30, 1999 Retrieved January 12, 2011, from http://www.accessdata.fda.gov/cdrh-docs/ pdf/P990004A.pdf
25. J. Li, R.L. Nation, J.D. Turnidge, R.W. Milne, K. Coulthard, C.R. Rayner, and D.L. Paterson Colistin: the re-emerging antibiotic for multidrug-resistant Gram-negative bacterial infections Lancet Infect. Dis. 6 2006 589 601
26. D.E. Karageorgopoulos, and M.E. Falagas Current control and treatment of multidrug-resistant Acinetobacter baumannii infections Lancet Infect. Dis. 8 2008 751 762
27. P. Scott, G. Deye, A. Srinivasan, C. Murray, K. Moran, E. Hulten, J. Fishbain, D. Craft, S. Riddell, L. Lindler, J. Mancuso, E. Milstrey, C.T. Bautista, J. Patel, A. Ewell, T. Hamilton, C. Gaddy, M. Tenney, G. Christopher, K. Petersen, T. Endy, and B. Petruccelli An outbreak of multidrug-resistant Acinetobacter baumannii-calcoaceticus complex infection in the US military health care system associated with military operations in Iraq Clin. Infect. Dis. 44 2007 1577 1584 (Pubitemid 46871504)
28. D.P. Crane, K. Gromov, D. Li, K. Søballe, C. Wahnes, H. Büchner, M.J. Hilton, R.J. O'Keefe, C.K. Murray, and E.M. Schwarz Efficacy of colistin-impregnated beads to prevent multidrug-resistant A. baumannii implant-associated osteomyelitis J. Orthop. Res. 27 2009 1008 1015
29. Z.S. Patel, M. Yamamoto, H. Ueda, Y. Tabata, and A.G. Mikos Biodegradable gelatin microparticles as delivery systems for the controlled release of bone morphogenetic protein-2 Acta Biomater. 4 2008 1126 1138
30. International Standard (ISO5833) implants for surgery-acrylic resin cements 2002
31. S. Young, A.G. Bashoura, T. Borden, L.S. Baggett, J.A. Jansen, M. Wong, and A.G. Mikos Development and characterization of a rabbit alveolar bone nonhealing defect model J. Biomed. Mater. Res. A 86 2008 182 194 (Pubitemid 351799499)
32. M.A. Haralson, and J.R. Hassell Extracellular Matrix: A Practical Approach 1995 Oxford University Press New York
33. Y. Yoshihara, H. Nakamura, K. Obata, H. Yamada, T. Hayakawa, K. Fujikawa, and Y. Okada Matrix metalloproteinases and tissue inhibitors of metalloproteinases in synovial fluids from patients with rheumatoid arthritis or osteoarthritis Ann. Rheum. Dis. 59 2000 455 461 (Pubitemid 30395603)
34. D. Taakiran, E. Taakiran, H. Ozsoy, and V. Lok Effects of surgical trauma on articular cartilage Tr. J. Med. Sci. 29 1999 177 180
35. T.A. Holland, J.K.A. Tessmar, Y. Tabata, and A.G. Mikos Transforming growth factor-ß1 release from oligo(poly(ethylene glycol) fumarate) hydrogels in conditions that model the cartilage wound healing environment J. Control. Release 94 2004 101 114 (Pubitemid 37542381)
36. J. Siepmann, and N.A. Peppas Modeling of drug release from delivery systems based on hydroxypropyl methylcellulose (HPMC) Adv. Drug Deliv. Rev. 48 2001 139 157 (Pubitemid 32434400)
37. L. Serra, J. Domenech, and N.A. Peppas Drug transport mechanisms and release kinetics from molecularly designed poly(acrylic acid-g-ethylene glycol) hydrogels Biomaterials 27 2006 5440 5451 (Pubitemid 44109896)
38. P.J. van Mullem, J.M. Vaandrager, J.P. Nicolai, and J.R. de Wijn Implantation of porous acrylic cement in soft tissues: an animal and human biopsy histological study Biomaterials 11 1990 299 304 (Pubitemid 20372075)
39. M.R. Virto, P. Frutos, S. Torrado, and G. Frutos Gentamicin release from modified acrylic bone cements with lactose and hydroxypropylmethylcellulose Biomaterials 24 2003 79 87 (Pubitemid 35300206)
40. D. Corry, and J. Moran Assessment of acrylic bone cement as a local delivery vehicle for the application of non-steroidal anti-inflammatory drugs Biomaterials 19 1998 1295 1301 (Pubitemid 28391476)
41. P. Frutos Cabanillas, E. Diez Pena, J.M. Barrales-Rienda, and G. Frutos Validation and in vitro characterization of antibiotic-loaded bone cement release Int. J. Pharm. 209 2000 15 26
42. H. van de Belt, D. Neut, D.R. Uges, W. Schenk, J.R. van Horn, H.C. van der Mei, and H.J. Busscher Surface roughness, porosity and wettability of gentamicin-loaded bone cements and their antibiotic release Biomaterials 21 2000 1981 1987 (Pubitemid 30433826)
43. J.C. Webb, and R.F. Spencer The role of polymethylmethacrylate bone cement in modern orthopaedic surgery J. Bone Joint Surg. Br. 89 2007 851 857 (Pubitemid 47322779)
44. J. Li, R.W. Milne, R.L. Nation, J.D. Turnidge, and K. Coulthard Stability of colistin and colistin methanesulfonate in aqueous media and plasma as determined by high-performance liquid chromatography Antimicrob. Agents Chemother. 47 2003 1364 1370 (Pubitemid 36368598)
45. P. Perez-Lozano, E. Garcia-Montoya, A. Orriols, M. Minarro, J.R. Tico, and J.M. Sune-Negre Application of a validated method in the stability study of colistin sulfate and methylparaben in a veterinary suspension formulation by high-performance liquid chromatography with a diode array detector J. AOAC Int. 90 2007 706 714 (Pubitemid 46945137)
46. R.V. Dudhani, R.L. Nation, and J. Li Evaluating the stability of colistin and colistin methanesulphonate in human plasma under different conditions of storage J. Antimicrob. Chemother. 65 2010 1412 1415
47. I. Galani, F. Kontopidou, M. Souli, P.D. Rekatsina, E. Koratzanis, J. Deliolanis, and H. Giamarellou Colistin susceptibility testing by Etest and disk diffusion methods Int. J. Antimicrob. Agents 31 2008 434 439
48. Z.S. Patel, H. Ueda, M. Yamamoto, Y. Tabata, and A.G. Mikos In vitro and in vivo release of vascular endothelial growth factor from gelatin microparticles and biodegradable composite scaffolds Pharm. Res. 25 2008 2370 2378
49. H. Park, J.S. Temenoff, T.A. Holland, Y. Tabata, and A.G. Mikos Delivery of TGF-beta1 and chondrocytes via injectable, biodegradable hydrogels for cartilage tissue engineering applications Biomaterials 26 2005 7095 7103 (Pubitemid 41095531)
50. T.A. Holland, Y. Tabata, and A.G. Mikos In vitro release of transforming growth factor-beta 1 from gelatin microparticles encapsulated in biodegradable, injectable oligo(poly(ethylene glycol) fumarate) hydrogels J. Control. Release 91 2003 299 313 (Pubitemid 36976762)