Evaluating the stability of colistin and colistin methanesulphonate in human plasma under different conditions of storage

Journal of Antimicrobial Chemotherapy

Volumn 65, Issue 7, 2010, Pages 1412-1415

  Dudhani, Rajesh V ^a   Nation, Roger L ^a   Li, Jian ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

HPLC; Pharmacokinetics pharmacodynamics; Polymyxins

Indexed keywords

COLISTIMETHATE; COLISTIN; ANTIINFECTIVE AGENT;

ARTICLE; DRUG BLOOD LEVEL; DRUG STABILITY; HUMAN; PHARMACODYNAMICS; STORAGE TEMPERATURE; TIME; ANALOGS AND DERIVATIVES; CHEMISTRY; FREEZING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LABORATORY DIAGNOSIS; PLASMA; PROCEDURES;

ANTI-BACTERIAL AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COLISTIN; DRUG STABILITY; FREEZING; HUMANS; PLASMA; SPECIMEN HANDLING; TIME FACTORS;

EID: 77954199174     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkq134     Document Type: Article

References (10)

1. Li J, Nation RL, Turnidge JD et al. Colistin: the re-emerging antibiotic for multidrug-resistant Gram-negative bacterial infections. Lancet Infect Dis 2006; 6: 589-601.
2. Aoki N, Tateda K, Kikuchi Y et al. Efficacy of colistin combination therapy in a mouse model of pneumonia caused by multidrug-resistant Pseudomonas aeruginosa. J Antimicrob Chemother 2009; 63: 534-42.
3. Li J, Rayner CR, Nation RL et al. Pharmacokinetics of colistin methanesulfonate and colistin in a critically ill patient receiving continuous venovenous hemodiafiltration. Antimicrob Agents Chemother 2005; 49: 4814-5.
4. Ma Z, Wang J, Gerber JP et al. Determination of colistin in human plasma, urine and other biological samples using LC-MS/MS. J Chromatogr B Analyt Technol Biomed Life Sci 2008; 862: 205-12.
5. Plachouras D, Karvanen M, Friberg LE et al. Population pharmacokinetic analysis of colistin methanesulfonate and colistin after intravenous administration in critically ill patients with infections caused by gram negative bacteria. Antimicrob Agents Chemother 2009; 53:3430-6.
6. Li J, Milne RW, Nation RL et al. Stability of colistin and colistin methanesulfonate in aqueous media and plasma as determined by high-performance liquid chromatography. Antimicrob Agents Chemother 2003; 47: 1364-70.
7. Wallace SJ, Li J, Rayner CR et al. Stability of colistin methanesulfonate in pharmaceutical products and solutions for administration to patients. Antimicrob Agents Chemother 2008; 52: 3047-51.
8. Li J, Coulthard K, Milne R et al. Steady-state pharmacokinetics of intravenous colistin methanesulphonate in patients with cystic fibrosis. J Antimicrob Chemother 2003; 52: 987-92.
9. Li J. Optimizing and preserving the activity of colistin. In: Abstracts of the Forty-ninth Interscience Conference on Antimicrobial Agents and Chemotherapy, San Francisco, CA, 2009. Abstract 1205, p. 82. American Society for Microbiology, Washington, DC, USA.
10. Cao G, Ali FEA, Chiu F et al. Development and validation of a reversed-phase high-performance liquid chromatography assay for polymyxin B in human plasma. J Antimicrob Chemother 2008; 62: 1009-14.