Is low digit ratio linked with late menarche? Evidence from the BBC internet study

American Journal of Human Biology

Volumn 23, Issue 4, 2011, Pages 527-533

  Manning, John T ^a   Fink, Bernhard ^b  

^a SWANSEA UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AGE; ARTICLE; CHILD; FEMALE; FINGER; HEALTH STATUS; HISTOLOGY; HUMAN; INTERNET; MENARCHE; MULTIVARIATE ANALYSIS; PREGNANCY; REFERENCE VALUE; SELF EVALUATION; STATISTICS; TIME; WOMEN'S HEALTH;

AGE FACTORS; CHILD; FEMALE; FINGERS; HEALTH STATUS; HUMANS; INTERNET; MENARCHE; MULTIVARIATE ANALYSIS; PREGNANCY; REFERENCE VALUES; SELF-ASSESSMENT; STATISTICS AS TOPIC; TIME FACTORS; WOMEN'S HEALTH;

HELLE;

EID: 79958082714     PISSN: 10420533     EISSN: 15206300     Source Type: Journal    
DOI: 10.1002/ajhb.21186     Document Type: Article

References (49)

1. Barker DJP. 1992. Fetal and infant origins of adult disease. London: BMJ Publishing.
2. Barut C, Tan U, Dogan A. 2008. Association of height and weight with second to fourth digit ratio (2D:4D) and sex differences. Percept Mot Skills 106: 627-632.
3. Berenbaum SA, Bryk KK, Nowak N, Quigley CA, Moffat S. 2009. Fingers as a marker of prenatal androgen exposure. Endocrinology 150: 5119-5124.
4. Brabin L, Roberts SA, Farzaneh F, Fairbrother E, Kitchener HC. 2008. The second to fourth digit ratio (2D:4D) in women with and without human papillomavirus and cervical dysplasia. Am J Hum Biol 20: 337-341.
5. Brown WM, Hines M, Fane BA, Breedlove SM. 2002. Masculinized finger length patterns in human males and females with congenital adrenal hyperplasia. Horm Behav 42: 380-386.
6. Buck JJ, Williams RM, Hughes IA, Acerini CL. 2003. In-utero androgen exposure and 2nd to 4th digit length ratio-comparisons between healthy controls and females with classical adrenal hyperplasia. Hum Reprod 18: 976-979.
7. Caswell N, Manning JT. 2009. A comparison of finger 2D:4D by self-report direct measurement and experimenter measurement from photocopy: methodological issues. Arch Sex Behav 38: 143-148.
8. Cattrall FR, Vollenhoven BJ, Weston GC. 2005. Anatomical evidence for in utero androgen exposure in women with polycystic ovary syndrome. Fertil Steril 84: 1689-1692.
9. Ciumas C, Linden Hirschberg A, Savic I. 2009. High fetal testosterone and sexually dimorphic cerebral networks in females. Cereb Cortex 19: 1167-1174.
10. Dumesic DA, Abbott DH, Padmanabhan V. 2007. Polycystic ovary syndrome and its developmental origins. Rev Endocr Metab Disord 8: 127-141.
11. Ellison PT. 2001. On fertile ground. A natural history of human reproduction. Cambridge, MA: Harvard University Press.
12. Ellison PT. 2005. Evolutionary perspectives on the fetal origins hypothesis. Am J Hum Biol 17: 113-118.
13. Fink B, Neave N, Manning JT. 2003. Second to fourth digit ratio, body mass index, waist-to-hip ratio, and waist-to-chest ratio: their relationships in heterosexual men and women. Ann Hum Biol 30: 728-738.
14. He C, Kraft P, Chen C, Buring JE, Paré G, Hankinson SE, Chanock SJ, Ridker PM, Hunter DJ, Chasman DI. 2009. Genome-wide association studies identify loci associated with age at menarche and age at natural menopause. Nat Genet 41: 724-728.
15. Helle S. 2010a. Does second-to-fourth digit length ratio (2D:4D) predict age at menarche in women? Am J Hum Biol 22: 418-420.
16. Helle S. 2010b. Digit length ratio (2D:4D) and variation in key life-history traits and fitness in contemporary Finnish women. Behav Ecol 21: 1061-1066.
17. Helm P, Münster K, Schmidt L. 1995. Recalled menarche in relation to infertility and adult weight and height. Acta Obstet Gynecol Scand 74: 718-722.
18. Himes JH, Roche AF. 1982. Reported versus measured adult statures. Am J Phys Anthropol 58: 335-341.
19. Hoenekopp J, Watson S. 2010. Meta-analysis of digit ratio 2D:4D shows greater sex difference in the right hand. Am J Hum Biol 22: 619-630.
20. Karapanou O, Papadimitriou A. 2010. Determinants of menarche. Rep Biol Endocrinol 8: 115.
21. Lujan ME, Bloski TG, Chizen DR, Lehotay DC, Pierson RA. 2010. Digit ratios do not serve as anatomical evidence of prenatal androgen exposure in clinical phenotypes of polycystic ovary syndrome. Hum Reprod 25: 204-211.
22. Lutchmaya S, Baron-Cohen S, Raggatt P, Knickmeyer R, Manning JT. 2004. 2nd to 4th digit ratios, fetal testosterone and estradiol. Early Hum Dev 77: 23-28.
23. Manning JT. 2002. Digit ratio: a pointer to fertility, behavior, and health. New Brunswick, NJ: Rutgers University Press.
24. Manning JT, Baron-Cohen S, Wheelwright S, Fink B. 2010. Is digit ratio related to systemizing and empathizing? Evidence from direct finger measurements reported in the BBC internet survey. Pers Indiv Diff 48: 767-771.
25. Manning JT, Bundred PE, Newton DJ, Flanagan BF. 2003. The second to the fourth digit ratio and variation in the androgen receptor gene. Evol Hum Behav 24: 399-405.
26. Manning JT, Churchill AJG, Peters M. 2007. The effects of sex, ethnicity and Sexual orientation on self-measured digit ratio (2D:4D). Arch Sex Behav 36: 223-233.
27. Manning JT, Fink B. 2008. Digit ratio (2D:4D), dominance, reproductive success, asymmetry, and sociosexuality in the BBC Internet Study. Am J Hum Biol 20: 451-461.
28. Manning JT, Fink B. 2011. Digit ratio, nicotine and alcohol intake and national rates of smoking and alcohol consumption. Pers Indiv Diff 50: 344-348.
29. Manning JT, Fink B. Digit ratio (2D:4D) and aggregate personality scores across nations: data from the BBC internet study. Pers Indiv Diff (in press).
30. Manning JT, Leinster S. 2001. Second to fourth digit ratio and age at presentation of breast cancer. The Breast 10: 355-357.
31. Manning JT, Scutt D, Wilson J, Lewis-Jones DI. 1998. The ratio of 2nd to 4th digit length: a predictor of sperm numbers and concentrations of testosterone, luteinizing hormone and oestrogen. Hum Reprod 13: 3000-3004.
32. Matchock RL. 2008. Low digit ratio (2D:4D) is associated with delayed menarche. Am J Hum Biol 20: 487-489.
33. Medland SE, Zayats T, Glaser B, Nyholt DR, Gordon SD, Wright MJ, Montgomery GW, Campbell MJ, Henders AK, Timpson NJ, Peltonen L, Wolke D, Ring SM, Deloukas P, Martin NG, Smith GD, Evans DM. 2010. A variant in LIN28B is associated with 2D:4D finger-length ratio, a putative retrospective biomarker of prenatal testosterone exposure. Am J Hum Genet 86: 519-525.
34. New MI. 2004. An update of congenital adrenal hyperplasia. Ann N Y Acad Sci 1038: 14-43.
35. O'Brien RM. 2007. A caution regarding rules of thumb for variance inflation factors. Qual Quant 41: 673-690.
36. Okten A, Kalyonku M, Yaris N. 2002. The ratio of second- and fourth digit lengths and congenital adrenal hyperplasia due to 21-hydroxylase deficiency. Early Hum Dev 70: 47-54.
37. Onland-Moret NC, Peeters PH, van Gils CH, Clavel-Chapelon F, Key T, Tjønneland A, Trichopoulou A, Kaaks R, Manjer J, Panico S, Palli D, Tehard B, Stoikidou M, Bueno-De-Mesquita HB, Boeing H, Overvad K, Lenner P, Quirós JR, Chirlaque MD, Miller AB, Khaw KT, Riboli E. 2005. Age at menarche in relation to adult height: the EPIC Study. Am J Epidemiol 162: 623-632.
38. Osuch JR, Karmaus W, Hoekman P, Mudd L, Zhang J, Haan P, Mikucki D. 2010. Association of age at menarche with adult leg length and trunk height: speculations in relation to breast cancer risk. Ann Hum Biol 37: 76-85.
39. Perry JR, Stolk L, Franceschini N, Lunetta KL, Zhai G. 2009. Meta-analysis of genome- wide association data identifies two loci influencing age at menarche. Nat Genet 41: 648-650.
40. Reimers S. 2007. The BBC internet study: general methodology. Arch Sex Behav 36: 147-161.
41. Ruder EH, Dorgan JF, Kranz S, Kris-Etherton PM, Hartman TJ. 2008. Examining breast cancer growth and lifestyle risk factors: early life, childhood, and adolescence. Clin Breast Cancer 8: 334-342.
42. Sadrzadeh S, Klip WA, Broekmans FJ, Schats R, Willemsen WN, Burger CW, Van Leeuwen FE, Lambalk CB. 2003. Birth weight and age at menarche in patients with polycystic ovary syndrome or diminished ovarian reserve, in a retrospective cohort. Hum Reprod 18: 2225-2230.
43. Sharma K, Talwar I, Sharma N. 1988. Age at menarche in relation to adult body size and physique. Ann Hum Biol 15: 431-434.
44. Steiner E, Klubert D, Knutson D. 2008. Assessing breast cancer risk in women. Am Fam Physician 78: 1361-1366.
45. Sulem P, Gudbjartsson DF, Rafnar T, Holm H, Olafsdottir EJ, Olafsdottir GH, Jonsson T, Alexandersen P, Feenstra B, Boyd HA, Aben KK, Verbeek AL, Roeleveld N, Jonasdottir A, Styrkarsdottir U, Steinthorsdottir V, Karason A, Stacey SN, Gudmundsson J, Jakobsdottir M, Thorleifsson G, Hardarson G, Gulcher J, Kong A, Kiemeney LA, Melbye M, Christiansen C, Tryggvadottir L, Thorsteinsdottir U, Stefansson K. 2009. Genome-wide association study identifies sequence variants on 6q21 associated with age at menarche. Nat Genet 41: 734-738.
46. van Noord PA, Kaaks R. 1991. The effect of wartime conditions and the 1944-45 'Dutch famine' on recalled menarcheal age in participants of the DOM breast cancer screening project. Ann Hum Biol 18: 57-70.
47. Velie EM, Nechuta S, Osuch JR. 2005. Lifetime reproductive and anthropometric risk factors for breast cancer in postmenopausal women. Breast Dis 24: 17-35.
48. Viswanathan SR, Powers JT, Einhorn W, Hoshida Y, Ng TL, Toffanin S, O'Sullivan M, Lu J, Phillips LA, Lockhart VL, Shah SP, Tanwar PS, Mermel CH, Beroukhim R, Azam M, Teixeira J, Meyerson M, Hughes TP, Llovet JM, Radich J, Mullighan CG, Golub TR, Sorensen PH, Daley GQ. 2009. LIN28B promotes transformation and is associated with advanced human malignancies. Nat Genet 41: 843-848.
49. Widén E, Ripatti S, Cousminer DL, Surakka I, Lappalainen T, Järvelin MR, Eriksson JG, Raitakari O, Salomaa V, Sovio U, Hartikainen AL, Pouta A, McCarthy MI, Osmond C, Kajantie E, Lehtimäki T, Viikari J, Kähönen M, Tyler-Smith C, Freimer N, Hirschhorn JN, Peltonen L, Palotie A. 2010. Distinct variants in LIN28B influence growth in height from birth to adulthood. Am J Hum Genet 86: 773-782.