Inhaled nitric oxide for acute respiratory distress syndrome and acute lung injury in adults and children: A systematic review with meta-analysis and trial sequential analysis

Anesthesia and Analgesia

Volumn 112, Issue 6, 2011, Pages 1411-1421

  Afshari, Arash ^a,b   Brok, Jesper ^c,d   Møller, Ann M ^a,b   Wetterslev, Jørn ^d  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b Mental Health Services CPH   (Denmark)

^c HVIDOVRE HOSPITAL   (Denmark)

^d Rigshospitalet   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID; METHEMOGLOBIN; NITRIC OXIDE; NITROGEN DIOXIDE; OXYGEN; PLACEBO;

ACUTE LUNG INJURY; ADULT RESPIRATORY DISTRESS SYNDROME; ARTIFICIAL VENTILATION; BLEEDING; BODY POSTURE; CHILDHOOD DISEASE; CHILDHOOD RESPIRATORY DISTRESS SYNDROME; CORTICOSTEROID THERAPY; COST BENEFIT ANALYSIS; DRUG DOSE TITRATION; DRUG EFFICACY; DRUG SAFETY; HUMAN; INTENSIVE CARE UNIT; KIDNEY DYSFUNCTION; LENGTH OF STAY; META ANALYSIS; MORTALITY; MULTIPLE ORGAN FAILURE; OXYGEN TENSION; OXYGEN THERAPY; PRIORITY JOURNAL; QUALITY OF LIFE; RESPIRATORY DISTRESS SYNDROME; REVIEW; SIDE EFFECT; SYSTEMATIC REVIEW; TREATMENT DURATION; UNSPECIFIED SIDE EFFECT;

EID: 79958078281     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/ANE.0b013e31820bd185     Document Type: Article

References (45)

1. Jain R, DalNogare A. Pharmacological therapy for acute respiratory distress syndrome. Mayo Clin Proc 2006;8:205-12 (Pubitemid 43205775)
2. Dahlem P, van Aalderen WM, Bos AP. Pediatric acute lung injury. Paediatr Respir Rev 2007;8:348-62 (Pubitemid 350102999)
3. Dellinger RP, Zimmerman JL, Taylor RW, Straube RC, Hauser DL, Criner GJ, Davis K Jr, Hyers TM, Papadakos P. Effects of inhaled nitric oxide in patients with acute respiratory distress syndrome: results of a randomized phase II trial. Inhaled Nitric Oxide in ARDS Study group. Crit Care Med 1998;26:15-23 (Pubitemid 28028435)
4. Sokol J, Jacobs SE, Bohn D. Inhaled nitric oxide for acute hypoxic respiratory failure in children and adults: a meta-analysis. Anesth Analg 2003;97:989-98 (Pubitemid 37158678)
5. McAndrew J, Patel RP, Jo H, Cornwell T, Lincoln T, Moellering D, White CR, Matalon S, Darley-Usmar V. The interplay of nitric oxide and peroxynitrite with signal transduction pathways: implications for disease. Semin Perinatol 1997;21:351-66 (Pubitemid 27459485)
6. Prodhan P, Noviski N. Pediatric acute hypoxemic respiratory failure: management of oxygenation. J Intensive Care Med 2004;19:140-53 (Pubitemid 44544705)
7. Adhikari NK, Burns KE, Friedrich JO, Granton JT, Cook DJ, Meade MO. Effect of nitric oxide on oxygenation and mortality in acute lung injury: systematic review and meta-analysis. BMJ 2007;334:779
8. Sokol J, Jacobs SE, Bohn D. Inhaled nitric oxide for acute hypoxemic respiratory failure in children and adults. Cochrane Database Syst Rev 2003;1:CD002787
9. Higgins JPT, Green S. Cochrane handbook for systematic reviews of interventions, Version 5.0.2. In: Higgins JPT, Green S, eds. The Cochrane Collaboration. Oxford, UK: Wiley, 2009
10. Wetterslev J, Thorlund K, Brok J, Gluud C. Trial sequential analysis may establish when firm evidence is reached in cumulative meta-analysis. J Clin Epidemiol 2008;61:64-75 (Pubitemid 350245732)
11. Atkins D, Best D, Briss PA, Eccles M, Falck-Ytter Y, Flottorp S, Guyatt GH, Harbour RT, Haugh MC, Henry D, Hill S, Jaeschke R, Leng G, Liberati A, Magrini N, Mason J, Middleton P, Mrukowicz J, O'Connell D, Oxman AD, Phillips B, Schünemann HJ, Edejer TT, Varonen H, Vist GE, Williams JW Jr, Zaza S; GRADE Working Group. Grading quality of evidence and strength of recommendations. BMJ 2004;328:1490
12. Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. J Clin Epidemiol 2009;62:1006-12
13. Afshari A, Brok J, Møller AM, Wetterslev J. Inhaled nitric oxide for acute respiratory distress syndrome (ARDS) and acute lung injury in children and adults. Cochrane Database Syst Rev 2010;7:CD002787
14. DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials 1986;7:177-88 (Pubitemid 17189972)
15. Demets DL. Methods for combining randomized clinical trials: strengths and limitations. Stat Med 1987;6:341-50
16. The Nordic Cochrane Centre. ReviewManager (RevMan). Version 5.0 ed. Copenhagen: The Cochrane Collaboration, 2008
17. Altman DG, Bland JM. Interaction revisited: the difference between two estimates. BMJ 2003;326:219 (Pubitemid 36143396)
18. Ibrahim TS, El-Mohamady HS. Inhaled nitric oxide and prone position: how far they can improve oxygenation in pediatric patients with acute respiratory distress syndrome? J Med Sci 2007;7:390-5 (Pubitemid 46860789)
19. Park KJ, Lee YJ, Oh YJ, Lee KS, Sheen SS, Hwang SC. Combined effects of inhaled nitric oxide and a recruitment maneuver in patients with acute respiratory distress syndrome. Yonsei Med J 2003;44:219-26 (Pubitemid 36592183)
20. Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ 1997;315:629-34 (Pubitemid 27387172)
21. Brok J, Thorlund K, Wetterslev J, Gluud C. Apparently conclusive meta-analyses may be inconclusive\trial sequential analysis adjustment of random error risk due to repetitive testing of accumulating data in apparently conclusive neonatal meta-analyses. Int J Epidemiol 2009;38:287-98
22. Thorlund K, Devereaux PJ, Wetterslev J, Guyatt G, Ioannidis JP, Thabane L, Gluud LL, Als-Nielsen B, Gluud C. Can trial sequential monitoring boundaries reduce spurious inferences from meta-analyses? Int J Epidemiol 2009;38:276-86
23. Pogue J, Yusuf S. Overcoming the limitations of current meta-analysis of randomised controlled trials. Lancet 1998;351:47-52 (Pubitemid 28020173)
24. Pogue JM, Yusuf S. Cumulating evidence from randomized trials: utilizing sequential monitoring boundaries for cumulative meta-analysis. Control Clin Trials 1997;18:580-93 (Pubitemid 27520846)
25. Wetterslev J, Thorlund K, Brok J, Gluud C. Estimating required information size by quantifying diversity in random-effects model meta-analyses. BMC Med Res Methodol 2009;9:86
26. Brozek J, Oxman A, Schunemann H. GRADEpro for Windows. 3.2 ed. 2008
27. Cuthbertson BH, Galley HF, Webster NR. Effect of inhaled nitric oxide on key mediators of the inflammatory response in patients with acute lung injury. Crit Care Med 2000;28:1736-41 (Pubitemid 30428721)
28. Day RW, Allen EM, Witte MK. A randomized, controlled study of the 1-hour and 24-hour effects of inhaled nitric oxide therapy in children with acute hypoxemic respiratory failure. Chest 1997;112:1324-31 (Pubitemid 27497867)
29. Mehta S, Simms HH, Levy MM, Hill NS, Schwartz W, Nelson D, Short K, Klinger JR. Inhaled nitric oxide improves oxygen-ation acutely but not chronically in acute respiratory distress syndrome: a randomized, controlled trial. J Appl Res Clin Exp Ther 2001;1:73-84
30. Payen D, Vallet B, group d'étude du NO dans l'ARDS. Results of the French prospective multicentric randomized double-blind placebo-controlled trial on inhaled nitric oxide (NO) in ARDS. Intensive Care Med 1999;25(Suppl 1):166
31. Taylor RW, Zimmerman JL, Dellinger RP, Straube RC, Criner GJ, Davis K Jr, Kelly KM, Smith TC, Small RJ. Inhaled nitric oxide in ARDS Study group. Low-dose inhaled nitric oxide in patients with acute lung injury: a randomized controlled trial. JAMA 2004;291:1603-9 (Pubitemid 38552433)
32. Troncy E, Collet JP, Shapiro S, Guimond JG, Blair L, Ducruet T, Francoeur M, Charbonneau M, Blaise G. Inhaled nitric oxide in acute respiratory distress syndrome: a pilot randomized controlled study. Am J Respir Crit Care Med 1998;157:1483-8
33. Dobyns EL, Cornfield DN, Anas NG, Fortenberry JD, Tasker RC, Lynch A, Liu P, Eells PL, Griebel J, Baier M, Kinsella JP, Abman SH. Multicenter randomized controlled trial of the effects of inhaled nitric oxide therapy on gas exchange in children with acute hypoxemic respiratory failure. J Pediatr 1999;134:406-12 (Pubitemid 30180620)
34. Lundin S, Mang H, Smithies M, Stenqvist O, Frostell C. Inhalation of nitric oxide in acute lung injury: results of a European multicentre study. The European Study Group of Inhaled Nitric Oxide. Intensive Care Med 1999;25:911-9 (Pubitemid 29452535)
35. Schwebel C, Beuret P, Perdrix JP, Jospe R, Duperret S, Fogliani J. Early inhaled nitric oxide inhalation in acute lung injury: results of a double-blind randomized study. Intens Care Med 1997;23(Suppl 1):2
36. Angus DC, Clermont G, Linde-Zwirble WT, Musthafa AA, Dremsizov TT, Lidicker J, Lave JR, NO-06 Investigators. Healthcare costs and long-term outcomes after acute respiratory distress syndrome: a phase III trial of inhaled nitric oxide. Crit Care Med 2006;34:2883-90 (Pubitemid 44808728)
37. Dobyns EL, Anas NG, Fortenberry JD, Deshpande J, Cornfield DN, Tasker RC, Liu P, Eells PL, Griebel J, Kinsella JP, Abman SH. Interactive effects of high-frequency oscillatory ventilation and inhaled nitric oxide in acute hypoxemic respiratory failure in pediatrics. Crit Care Med 2002;30:2425-9 (Pubitemid 35351858)
38. Michael JR, Barton RG, Saffle JR, Mone M, Markewitz BA, Hillier K, Elstad MR, Campbell EJ, Troyer BE, Whatley RE, Liou TG, Samuelson WM, Carveth HJ, Hinson DM, Morris SE, Davis BL, Day RW. Inhaled nitric oxide versus conventional therapy: effect on oxygenation in ARDS. Am J Respir Crit Care Med 1998;157:1372-80
39. Gerlach H, Keh D, Semmerow A, Busch T, Lewandowski K, Pappert DM, Rossaint R, Falke KJ. Dose-response characteristics during long-term inhalation of nitric oxide in patients with severe acute respiratory distress syndrome: a prospective, randomized, controlled study. Am J Respir Crit Care Med 2003;167:1008-15 (Pubitemid 36408167)
40. Petrucci N, Iacovelli W. Lung protective ventilation strategy for the acute respiratory distress syndrome. Cochrane Database Syst Rev 2007;3:CD003844
41. Briel M, Meade M, Mercat A, Brower RG, Talmor D, Walter SD, Slutsky AS, Pullenayegum E, Zhou Q, Cook D, Brochard L, Richard JC, Lamontagne F, Bhatnagar N, Stewart TE, Guyatt G. Higher vs lower positive end-expiratory pressure in patients with acute lung injury and acute respiratory distress syndrome: systematic review and meta-analysis. JAMA 2010; 303:865-73
42. Kass LJ, Apkon M. Inhaled nitric oxide in the treatment of hypoxemic respiratory failure. Curr Opin Pediatr 1998; 10:284-90 (Pubitemid 28419809)
43. The Acute Respiratory Distress Syndrome Network. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. NEJM 2000;342:1301-8
44. Petrucci N, Iacovelli W. Lung protective ventilation strategy for the acute respiratory distress syndrome. Cochrane Database Syst Rev 2007;3:CD003844
45. Valdivielso JM, Blantz RC. Acute renal failure: is nitric oxide the bad guy? Antioxid Redox Signal 2002;4:925-34 (Pubitemid 36042468)