Single impact trauma in human early-stage osteoarthritic cartilage: Implication of prostaglandin D2 but no additive effect of IL-1β on cell survival

International Journal of Molecular Medicine

Volumn 28, Issue 2, 2011, Pages 271-277

  Joos, Helga ^a   Hogrefe, Cathrin ^a   Rieger, Lucia ^a   Dürselen, Lutz ^a   Ignatius, Anita ^a   Brenner, Rolf E ^a  

^a UNIVERSITY OF ULM   (Germany)

Author keywords

Cartilage; Cell death; IL 1 ; p38MAPK; Prostaglandin D2; Prostaglandin E2; Trauma

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; INTERLEUKIN 1BETA; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; PROSTAGLANDIN D2; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CARTILAGE INJURY; CELL METABOLISM; CELL SURVIVAL; CELL VIABILITY; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME INHIBITION; EXPLANT; GENE EXPRESSION; HUMAN; HUMAN TISSUE; INFLAMMATION; MOLECULAR INTERACTION; OSTEOARTHRITIS; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; SIGNAL TRANSDUCTION; SYNTHESIS; TIME; UPREGULATION;

AGED; AGED, 80 AND OVER; CARTILAGE, ARTICULAR; CELL SURVIVAL; CHONDROCYTES; CYTOKINES; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; HUMANS; IMIDAZOLES; INFLAMMATION MEDIATORS; INTERLEUKIN-1BETA; MIDDLE AGED; NITRIC OXIDE SYNTHASE TYPE II; OSTEOARTHRITIS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROSTAGLANDIN D2; PYRIDINES; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 79958077821     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2011.694     Document Type: Article

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